Chapter 4
Modes of action and toxicity pathways
What are “toxicokinetic phase” and “toxicodynamic phase”?
What is the main purpose of xenobiotic metabolism and what are its three major steps?
Explain the terms “molecular initiating event (MIE)” and “key events (KE)”. Give an example for each.
What is the difference between agonism and antagonism?
What is the difference between nonspecific and specific toxicity?
What is the role of adaptive stress response?