Bioanalytical Tools

Regarding more complicated environmental matrices like sediment, soil, particles, biota and tissues, we need to separate the chemicals from matrices before further analysis and bioassays. For risk assessment of chemical mixtures in environmental samples, it is crucial to ensure that the extraction method will not alter the original concentrations and compositions of chemicals in samples. Please list several valid methods for the isolation and clean-up of solid samples and describe what kind of samples they are typically applied for.

What methods can be used to assess the immediate risk and total hazard potential of sediment?

Will the coextracted materials like lipids impact on the accuracy of risk assessment? Why? How to avoid this influence?