Dr. Florian Centler


Dr. Florian Centler

Department of Environmental Microbiology
Working Group Systems Biology of Microbial Communities
Helmholtz Centre for
Environmental Research - UFZ
Permoserstr. 15, 04318 Leipzig, Germany

Phone +49 341 235-1336

Florian Centler

CV / Scientific Career

since 03/2015

Junior research group leader Systems Biology of Microbial Communities, Helmholtz Centre for Environmental Research - UFZ, Department of Environmental Microbiology (UMB), Leipzig


Scientist in the Young Investigators Group GReaT MoDE, Helmholtz Centre for Environmental Research - UFZ, Department of Environmental Microbiology (UMB), Leipzig


PhD student in the Bio Systems Analysis Group, Friedrich-Schiller-University of Jena


Part-time studies in economics, Distance University of Hagen


Studies in Applied Systems Science, University of Osnabrück


  • Bonk, F., Popp, D., Weinrich, S., Sträuber, H., Becker, D., Kleinsteuber, S., Harms, H., Centler, F., (2019):
    Determination of microbial maintenance in acetogenesis and methanogenesis by experimental and modeling techniques
    Front. Microbiol. 10 , art. 166
    Volltext (URL)
  • König, S., Köhnke, M.C., Firle, A.-L., Banitz, T., Centler, F., Frank, K., Thullner, M., (2019):
    Disturbance size can be compensated for by spatial fragmentation in soil microbial ecosystems
    Front. Ecol. Evol. 7 , art. 290
    Volltext (URL)
  • Weinrich, S., Koch, S., Bonk, F., Popp, D., Benndorf, D., Klamt, S., Centler, F., (2019):
    Augmenting biogas process modeling by resolving intracellular metabolic activity
    Front. Microbiol. 10 , art. 1095
    Volltext (URL)
  • Bonk, F., Popp, D., Harms, H., Centler, F., (2018):
    PCR-based quantification of taxa-specific abundances in microbial communities: Quantifying and avoiding common pitfalls
    J. Microbiol. Methods 153 , 139 - 147
    Volltext (URL)
  • Bonk, F., Popp, D., Weinrich, S., Sträuber, H., Kleinsteuber, S., Harms, H., Centler, F., (2018):
    Ammonia inhibition of anaerobic volatile fatty acid degrading microbial communities
    Front. Microbiol. 9 , art. 2921
    Volltext (URL)
  • Bonk, F., Popp, D., Weinrich, S., Sträuber, H., Kleinsteuber, S., Harms, H., Centler, F., (2018):
    Intermittent fasting for microbes: how discontinuous feeding increases functional stability in anaerobic digestion
    Biotechnol. Biofuels 11 , art. 274
    Volltext (URL)
  • Harnisch, F., Blombach, B., Buyel, J., Centler, F., Classen, T., Ebert, B.E., Eyer, C., Dohnt, K., Grünberger, A., Jandt, U., Jung, S., Kara, S., Regestein, L., Schmid, J., Tischler, D., Wierckx, N., (2018):
    Revisionsbedürftig? Rechte und Pflichten akademischer Nachwuchsführungskräfte
    Forschung & Lehre 25 (9), 788 - 789
  • König, S., Worrich, A., Banitz, T., Centler, F., Harms, H., Kästner, M., Miltner, A., Wick, L.Y., Thullner, M., Frank, K., (2018):
    Spatiotemporal disturbance characteristics determine functional stability and collapse risk of simulated microbial ecosystems
    Sci. Rep. 8 , art. 9488
    Volltext (URL)
  • König, S., Worrich, A., Banitz, T., Harms, H., Kästner, M., Miltner, A., Wick, L.Y., Frank, K., Thullner, M., Centler, F., (2018):
    Functional resistance to recurrent spatially heterogeneous disturbances is facilitated by increased activity of surviving bacteria in a virtual ecosystem
    Front. Microbiol. 9 , art. 734
    Volltext (URL)
  • Liu, Z., Cichocki, N., Bonk, F., Günther, S., Schattenberg, F., Harms, H., Centler, F., Müller, S., (2018):
    Ecological stability properties of microbial communities assessed by flow cytometry
    mSphere 3 (1), e00564-17
    Volltext (URL)
  • König, S., Worrich, A., Centler, F., Wick, L.Y., Miltner, A., Kästner, M., Thullner, M., Frank, K., Banitz, T., (2017):
    Modelling functional resilience of microbial ecosystems: Analysis of governing processes
    Environ. Modell. Softw. 89 , 31 - 39
    Volltext (URL)
  • Worrich, A., Stryhanyuk, H., Musat, N., König, S., Banitz, T., Centler, F., Frank, K., Thullner, M., Harms, H., Richnow, H.-H., Miltner, A., Kästner, M., Wick, L.Y., (2017):
    Mycelium-mediated transfer of water and nutrients stimulates bacterial activity in dry and oligotrophic environments
    Nat. Commun. 8 , art. 15472
    Volltext (URL)
  • Alvarez-Zaldívar, P., Centler, F., Maier, U., Thullner, M., Imfeld, G., (2016):
    Biogeochemical modelling of in situ biodegradation and stable isotope fractionation of intermediate chloroethenes in a horizontal subsurface flow wetland
    Ecol. Eng. 90 , 170 - 179
    Volltext (URL)
  • Berthold, T., Centler, F., Hübschmann, T., Remer, R., Thullner, M., Harms, H., Wick, L.Y., (2016):
    Mycelia as a focal point for horizontal gene transfer among soil bacteria
    Sci. Rep. 6 , art. 36390
    Volltext (URL)
  • Coban, H., Miltner, A., Centler, F., Kästner, M., (2016):
    Effects of compost, biochar and manure on carbon mineralization of biogas residues applied to soil
    Eur. J. Soil Sci. 67 (2), 217 - 225
    Volltext (URL)
  • Wintsche, B., Glaser, K., Sträuber, H., Centler, F., Liebetrau, J., Harms, H., Kleinsteuber, S., (2016):
    Trace elements induce predominance among methanogenic activity in anaerobic digestion
    Front. Microbiol. 7 , art. 2034
    Volltext (URL)
  • Worrich, A., König, S., Banitz, T., Centler, F., Frank, K., Thullner, M., Harms, H., Miltner, A., Wick, L.Y., Kaestner, M., (2016):
    Bacterial dispersal promotes biodegradation in heterogeneous systems exposed to osmotic stress
    Front. Microbiol. 7 , art. 1214
    Volltext (URL)
  • Worrich, A., König, S., Miltner, A., Banitz, T., Centler, F., Frank, K., Thullner, M., Harms, H., Kästner, M., Wick, L.Y., (2016):
    Mycelium-like networks increase bacterial dispersal, growth, and biodegradation in a model ecosystem at various water potentials
    Appl. Environ. Microb. 82 (10), 2902 - 2908
    Volltext (URL)
  • Centler, F., Thullner, M., (2015):
    Chemotactic preferences govern competition and pattern formation in simulated two-strain microbial communities
    Front. Microbiol. 6 , art. 40
    Volltext (URL)
  • Gharasoo, M., Centler, F., van Cappellen, P., Wick, L.Y., Thullner, M., (2015):
    Kinetics of substrate biodegradation under the cumulative effects of bioavailability and self-inhibition
    Environ. Sci. Technol. 49 (9), 5529 - 5537
    Volltext (URL)
  • Richter, S., Fetzer, I., Thullner, M., Centler, F., Dittrich, P., (2015):
    Towards rule-based metabolic databases: a requirement analysis based on KEGG
    Int. J. Data Min. Bioinform. 13 (3), 289 - 319
    Volltext (URL)
  • Gharasoo, M., Centler, F., Fetzer, I., Thullner, M., (2014):
    How the chemotactic characteristics of bacteria can determine their population patterns
    Soil Biol. Biochem. 69 , 346 - 358
    Volltext (URL)
  • Centler, F., Heße, F., Thullner, M., (2013):
    Estimating pathway-specific contributions to biodegradation in aquifers based on dual isotope analysis: theoretical analysis and reactive transport simulations
    J. Contam. Hydrol. 152 , 97 - 116
    Volltext (URL)
  • Leibeling, S., Maeß, M.B., Centler, F., Kleinsteuber, S., von Bergen, M., Thullner, M., Harms, H., Müller, R.H., (2013):
    Posttranslational oxidative modification of (R)-2-(2,4-dichlorophenoxy)propionate/α-ketoglutarate-dependent dioxygenases (RdpA) leads to improved degradation of 2,4-dichlorophenoxyacetate (2,4-D)
    Eng. Life Sci. 13 (3), 278 - 291
    Volltext (URL)
  • Nick, H.M., Raoof, A., Centler, F., Thullner, M., Regnier, P., (2013):
    Reactive dispersive contaminant transport in coastal aquifers: Numerical simulation of a reactive Henry problem
    J. Contam. Hydrol. 145 , 90 - 104
    Volltext (URL)
  • Gharasoo, M., Centler, F., Regnier, P., Harms, H., Thullner, M., (2012):
    A reactive transport modeling approach to simulate biogeochemical processes in pore structures with pore-scale heterogeneities
    Environ. Modell. Softw. 30 (1), 102 - 114
    Volltext (URL)
  • Kalbacher, T., Delfs, J.-O., Shao, H., Wang, W., Walther, M., Samaniego, L., Schneider, C., Kumar, R., Musolff, A., Centler, F., Sun, F., Hildebrandt, A., Liedl, R., Borchardt, D., Krebs, P., Kolditz, O., (2012):
    The IWAS-ToolBox: software coupling for an integrated water resources management
    Environ. Earth Sci. 65 (5), 1367 - 1380
    Volltext (URL)
  • Thullner, M., Centler, F., Richnow, H.-H., Fischer, A., (2012):
    Quantification of organic pollutant degradation in contaminated aquifers using compound specific stable isotope analysis – Review of recent developments
    Org. Geochem. 42 (12), 1440 - 1460
    Volltext (URL)
  • Centler, F., Fetzer, I., Thullner, M., (2011):
    Modeling population patterns of chemotactic bacteria in homogenous porous media
    J. Theor. Biol. 287 , 82 - 91
    Volltext (URL)
  • Altenburger, R., Berns, A.E., Bittens, M., Brack, W., Burauel, P., Centler, F., Daus, B., Goss, K.-U., Harms, H., Kopinke, F.-D., Kühnel, D., Liess, M., Mackenzie, K., Miltner, A., Thullner, M., Wennrich, R., Wick, L.Y., (2010):
    Chemicals in the environment (CITE). Report of the First Annual Conference of the Helmholtz research topic CITE
    UWSF 22 (4), 502 - 506
    Volltext (URL)
  • Centler, F., Kaleta, C., Speroni di Fenizio, P., Dittrich, P., (2010):
    A parallel algorithm to compute chemical organizations in biological networks
    Bioinformatics 26 (14), 1788 - 1789
    Volltext (URL)
  • Centler, F., Shao, H., De Biase, C., Park, C.-H., Regnier, P., Kolditz, O., Thullner, M., (2010):
    GeoSysBRNS-A flexible multidimensional reactive transport model for simulating biogeochemical subsurface processes
    Comput. Geosci. 36 (3), 397 - 405
    Volltext (URL)
  • Benkö, G., Centler, F., Dittrich, P., Flamm, C., Stadler, B.M.R., Stadler, P.F., (2009):
    A topological approach to chemical organizations
    Artif. Life 15 (1), 71 - 88
    Volltext (URL)
  • Centler, F., Fetzer, I., Thullner, M., (2009):
    Modelling bacterial metapopulations
    8th German Workshop on Artifical Life - GWAL-8, Leipzig, 3.7.-1.8.2008
    p. 73 - 77
  • Shao, H., Centler, F., De Biase, C., Thullner, M., Kolditz, O., (2009):
    Comments on "Two-dimensional concentration distribution for mixing-controlled bioreactive transport in steady-state" by O.A. Cirpka and A.J. Valocchi
    Adv. Water Resour. 32 (2), 293 - 297
    Volltext (URL)