Dr. phil. Gudrun Liebscher

Postdoc in the Functional Genomics group


Department Molecular Systems Biology (MOLSYB)
Helmholtz-Zentrum für Umweltforschung - UFZ
Permoser Str. 15
04318 Leipzig

Tel: +49 341 235 1078    


scientific network

Research interests

  • Proteomics
  • Proteomic analysis of the effects of plasticisers on adipocyte differentiation and function


Nov 2021 - today

Helmholtz-Zentrum für Umweltforschung, Leipzig

2015 - 2021

Cell Biology, Biocenter, Medical Universität of Innsbruck
The LAMTOR complex is necessary for adipose tissue homeostasis


Research stay
Institute for Biochemistry and Molecular cell biology, UKE Hamburg-Eppendorf


Research stay
Institute for Molecular biology and Biochemistry, Medical University Graz


M.Sc. in Biochemistry
Martin-Luther-Universität Halle-Wittenberg
Testing of new antitumour agents on primary equine tumour cells and contributions to the elucidation of the mechanism of action


Erasmus internship
Institute of Molecular Pharmacology, University of Copenhagen
Pharmacological testing of new N-benzylphenethylamines as serotonine receptor 2A - agonists

2009 - 2012

B.Sc. in Biochemistry
Martin-Luther-Universität Halle-Wittenberg
Investigation of the in vivo import of plastidic precursor proteins via EGFP fusion and BN-PAGE



Cattelani C, Lesiak D, Liebscher G, Singer II, Stasyk T, Wallnöfer MH, Heberle AM, Corti C, Hess MW, Pfaller K, Kwiatkowski M, Pramstaller PP, Hicks AA, Thedieck K, Müller T, Huber LA, de Araujo MEG. The SZT2 interactome unravels new functions of the KICSTOR complex. Cells. 10 (10), 2711.


Jensen AA, Halberstadt AL, Märcher-Rørsted E, Odland AU, Chatha M, Speth N, Liebscher G, Hansen M, Bräuner-Osborne H, Palner M, Andreasen JT, Kristensen JL. The selective 5-HT2A receptor agonist 25CN-NBOH: Structure-activity relationship, in vivo pharmacology, and in vitro and ex vivo binding characteristics of [3H]25CN-NBOH. Biochem Pharmacol. 177:113979.

de Araújo MEG, Liebscher G, Hess MW, Huber LA. Lysosomal size matters. Traffic. 21(1):60–75.


Yordanov TE, Hipolito VEB, Liebscher G, Vogel GF, Stasyk T, Herrmann C, Geley S, Teis D, Botelho RJ, Hess MW, Huber LA. Biogenesis of lysosome-related organelles complex-1 (BORC) regulates late endosomal/lysosomal size through PIKfyve-dependent phosphatidylinositol-3,5-bisphosphate. Traffic. 20(9):674–96.


Heine M, Fischer AW, Schlein C, Jung C, Straub LG, Gottschling K, Mangels N, Yuan Y, Nilsson SK, Liebscher G, Chen O, Schreiber R, Zechner R, Scheja L, Heeren J. Lipolysis Triggers a Systemic Insulin Response Essential for Efficient Energy Replenishment of Activated Brown Adipose Tissue in Mice. Cell Metabolism. 2018, 28(4):1-12.

Jensen AA, McCorvy JD, Leth-Petersen S, Bundgaard C, Liebscher G, Kenakin TP, Brauner-Osborne H, Kehler J, Kristensen JL. Detailed Characterization of the In Vitro Pharmacological and Pharmacokinetic Properties of N-(2-Hydroxybenzyl)-2,5-Dimethoxy-4-Cyanophenylethylamine (25CN-NBOH), a Highly Selective and Brain-Penetrant 5-HT2A Receptor Agonist. J Pharmacol Exp Ther. 361:441-53.


Liebscher G, Vanchangiri K, Mueller T, Feige K, Cavalleri JM, Paschke R. In vitro anticancer activity of Betulinic acid and derivatives thereof on equine melanoma cell lines from grey horses and in vivo safety assessment of the compound NVX-207 in two horses. Chem Biol Interact. 246:20-9.

Hansen M, Jacobsen SE, Plunkett S, Liebscher G, McCorvy JD, Brauner-Osborne H, Kristensen JL. Synthesis and pharmacological evaluation of N-benzyl substituted 4-bromo-2,5-dimethoxyphenethylamines as 5-HT2A/2C partial agonists. Bioorg Med Chem. 23:3933-7.