Dr. Micjel Chávez Morejón
Contact
Dr. Micjel Chávez Morejón
Senior Scientist
Department of Microbial Biotechnology
Electrobiotechnology
Helmholtz Centre for
Environmental Research - UFZ
Permoserstr. 15, 04318 Leipzig, Germany
Phone: +49 341 6025-1315
micjel.chavez-morejon@ufz.de
Scientific Career
since October 2020
Senior Scientist at Department of Environmental Microbiology
Helmholtz Centre for Environmental Research – UFZ, Leipzig, Germany
2018 − 2020
Research Associate & Project Manager – ASM Research Chemicals GmbH
2016 − 2018
Post-doctoral Studies – Leibniz Institute of Plant Biochemistry, IPB, Halle (Saale), Germany
2012 − 2016
PhD Studies (Summa-Cum-Laude) – Leibniz Institute of Plant Biochemistry (IPB), Halle (Saale) and Martin-Luther University Halle-Wittenberg, Germany
Title: New Multicomponent Strategies to Cyclic Lipopeptides
2011 − 2016
Instructor of Organic and Biomolecular Chemistry – Faculty of Chemistry, University of Havana, Cuba
2009 − 2016
Research Associate – Center for Natural Products Research, Faculty of Chemistry, University of Havana, Cuba
2009 − 2011
M.Sc. Studies in Organic Chemistry (Distinction) – Faculty of Chemistry, University of Havana, Cuba
Research topic: Multicomponent synthesis of policationics peptidomimetics hybrids of peptide-peptoid
2006 − 2007
Internship in Biotechnological Industry – Cuban Center for Genetic Engineering and Biotechnology
2004 − 2009
Diploma Studies in Chemistry (Distinction) – Center for Natural Products Research, Faculty of Chemistry, University of Havana, Cuba
Research topic: Synthesis of peptidomimetics with potential antibacterial activity
Research interests
Index:
You could use our publication index for further requests.
2024 (2)
- Dai, S., Harnisch, F., Chávez Morejón, M., Keller, N.S., Korth, B., Vogt, C. (2024):
Microbial electricity-driven anaerobic phenol degradation in bioelectrochemical systems
Environ. Sci. Ecotechnol. 17 , art. 100307 10.1016/j.ese.2023.100307 - Hmedat, A.N., Chávez Morejón, M., Rivera, D.G., Pantelic, N.Đ., Wessjohann, L.A., Kaluđerović, G.N. (2024):
In vitro anticancer studies of a small library of cyclic lipopeptides against the human cervix adenocarcinoma HeLa cells
J. Serb. Chem. Soc. 89 (4), 471 - 484 10.2298/JSC240109018H
2023 (2)
- Chávez Morejón, M., Franz, A., Karande, R., Harnisch, F. (2023):
Integrated electrosynthesis and biosynthesis for the production of adipic acid from lignin-derived phenols
Green Chem. 25 (12), 4662 - 4666 10.1039/D3GC01105D - Chávez Morejón, M., Kurig, N., Tschauder, Y.S., Harnisch, F., Palkovits, R. (2023):
Electrochemical cellobiose valorization: Anodic oxidation to cellobionic acid and cathodic reduction to cellobitol
ChemistrySelect 8 (27), e202301823 10.1002/slct.202301823
2022 (1)
- Neubert, K., Hell, M., Chávez Morejón, M., Harnisch, F. (2022):
Hetero-coupling of bio-based medium chain carboxylic acids by Kolbe electrolysis enables high fuel yield and efficiency
ChemSusChem 15 (21), e202201426 10.1002/cssc.202201426
2021 (1)
- Harnisch, F., Chávez Morejón, M. (2021):
Hydrogen from water is more than a fuel: Hydrogenations and hydrodeoxygenations for a biobased economy
Chem. Rec. 21 (9), 2277 - 2289 10.1002/tcr.202100034
Peer-reviewed Publications
Morejón, M. C.; Puentes, A. R.; Rivera, D. G.; Wessjohann, L. A. Peptide Macrocyclization Assisted by Traceless Turn Inducers Derived from Ugi Peptide Ligation with Cleavable and Resin-Linked Amines. Org. Lett. 2017, 19, 4022–4025. DOI: 10.1021/acs.orglett.7b01761
Morejón, M. C.; Laub, A.; Kaluđerović, G. N.; Puentes, A. R.; Hmedat, A. N.; Otero-González, A. J.; Rivera, D. G.; Wessjohann, L. A. A Multicomponent Macrocyclization Strategy to Natural Product-Like Cyclic Lipopeptides: Synthesis and Anticancer Evaluation of Surfactin and Mycosubtilin Analogues. Org. Biomol. Chem. 2017, 15, 3628–3637. DOI: 10.1039/C7OB00459A
Morejón, M. C.; Laub, A.; Westermann, B.; Rivera, D. G.; Wessjohann, L. A. Solution and Solid-Phase Macrocyclization of Peptides by the Ugi-Smiles Multicomponent Reaction: Synthesis of N-Aryl-Bridged Cyclic Lipopeptides. Org. Lett. 2016, 18 (16), 4096–4099. DOI: 10.1021/acs.orglett.6b02001
Wessjohann, L. A.; Morejón, M. C.; Ojeda, G. M.; Rhoden, C. R. B.; Rivera, D. G. Applications of Convertible Isonitriles in the Ligation and Macrocyclization of Multicomponent Reaction-Derived Peptides and Depsipeptides. J. Org. Chem. 2016, 81 (15), 6535–6545. DOI: 10.1021/acs.joc.6b01150
Neves, R. A. W.; Stark, S.; Morejón, M. C.; Westermann, B.; Wessjohann, L. A. 4-Isocyanopermethylbutane-1,1,3-triol (IPB): a convertible isonitrile for multicomponent reactions. Tetrahedron Letters 2012, 53 (40), 5360-5363. Highlighted in: Chem Inform 2013, 44, 0520. DOI: 10.1016/j.tetlet.2012.07.064
Book Chapters
Wessjohann, L. A.; Neves Filho, R. A.; Puentes, A. R.; Morejón, M. C. Macrocycles from Multicomponent Reactions, In Practical Medicinal Chemistry with Macrocycles: Design, Synthesis, and Case Studies, Eds. Marsault, E.; Peterson, M. L. Wiley-Blackwell, 2017, pp 339.
Wessjohann, L. A.; Neves Filho, R.A.W.; Puentes, A.R.; Morejón, M.C. Macrocycles from Multicomponent Reactions, In Multicomponent Reactions in Organic Synthesis, 1st Edition. Zhu, J.; Wang, Q.; Wang, M. Eds. Wiley-VCH Verlag GmbH & Co. KGaA, 2015, pp 231.
Wessjohann, L. A.; Kaluderovic, G.; Neves Filho, R.A.W.; Morejón, M.C.; Lemanski, G.; Ziegler, T. Ed. Müller T.J.J. Multicomponent reactions 1. In Science of Synthesis, 2013, pp 415.
- Morejón, M.C.; Neves Filho, R.A.W.; Puentes, A.R.; Westermann, B.; Wessjohann, L. A.; PS-IPB as a new resin-immobilized convertible isonitrile for multicomponent reactions. At 6th International Conference on Multi-Component Reactions and Related Chemistry (MCR 2015), Brasilia, Brazil
- Morejón, M.C.; Neves Filho, R.A.W.; Stark, S.; Rivera, D.G.; Westermann, B.; Wessjohann, L. A.; Total synthesis of Spiroidesin a homotyrosine-containing lipopeptide. At 18th European Symposium on Organic Chemistry (ESOC 2013), Marseille, France. Poster presentation