Dr. Andrea Müller

Scientific Assistent
Biologist for Toxicology and Environment

Contakt

Helmholtz Centre for Environmental Research-UFZ, Leipzig
Department Molecular Systems Biology
Permoserstr. 15
04318 Leipzig

Phone +49 341 235 1541
Persönliche Bild

Scientific network


Actual projects

Risk assessment of fine particulate matter under changing climatic conditions
DAAD-DST India
DAAD-COLCIENCIAS Columbia

Air quality and associated effects in urban area is a major issue in both developed and developing countries. Recent studies showed correlation between respiratory problems, mortality rate and premature death with air pollution levels, especially fine paticulate matter (PM).
Actual projects are focused on risk assessment of air contaminants in megacities in Asia and Latin America. We intended to characterize the size, morphology, composition and toxicity of PM in contrasting environments of urban area. Additionally the exposure to volatile compounds (VOC, NO, O3, SO2) will be determined.

Air particulate matter will be collected on different exposed places the content of polycyclic aromatic hydrocarbons (PAHs) and their derivatives will be analyzed. Using a new developed method 65 PAHs can be analysed simultaneously which is important for a better risk assessment. The biological impact on human cells lines will be investigated. Different bioassays will be used to acquire more information about the underlying mechanism of particle associated health effects.

Using specific statistical models the spatiotemporal distribution and expansion of air contaminants as well as their health risk will be estimated under changing climatic conditions.

further information: Uwe Schlink ; IP Urban Transformation


Research Interest

  • Health Risk assessment of environmental indoor and outdoor contaminants
  • Development of methods for analyses of PAHs in particulate matter
  • Impact of environmental pollutant compounds on cell systems
  • Analysis of chemical compounds bound on air particles
  • Statistical analysis of association between exposure and health outcome


Curriculum vitae

since 2016 Scientific Assistant, Department Molecular Systems Biology, Helmholtz Centre for Environmental Research-UFZ, Leipzig
2012 PhD (Dr. rer.med.), University of Leipzig, Faculty of Medicine, Health impact of indoor mould exposure
2009-2015 Scientific Assistant, Head of the microbiological laboratory, Department Proteomic, Helmholtz Centre for Environmental Research-UFZ, Leipzig
2007-2009 post graduate study „Toxicology and Environment“, University of Leipzig, degree: Biologist for Toxicology
1992-2008 Scientific Assistant, Head of the microbiological laboratory,
Department Exposure Research and Epidemiology, Helmholtz Centre for Environmental Research-UFZ, Leipzig
1984-1992 Scientific Assistant,  Institute for Biotechnology, Leipzig
1979-1984 Friedrich-Schiller University of Jena, Diplom Biology, Specialization: Microbiology

Cooperations

International Projects
since DAAD-DST Indien, IIT Madras, Chennai
Toxicity and exposure assessment of fine particulate matter under changing climatic conditions
2016-2017 Indo-German Centre for Sustainability “Air Quality Management System to study the vulnerability and health risk due to air pollution and climate change in urban areas”
2015-2016 DAAD-COLCIENCIAS, Columbia, National University Columbia, Medellin; Risk Assessment of airborne particulate matter
2007-2008 BMBF - MINCYT, Argentine, National University Argentine, La Plata
Children's environmental health: Combined VOC and mould exposure as risk factor for respiratory diseases and allergies
2005-2008 EU-Project NOMIRACLE - Novel Methods for Integrated Risk Assessment of Cumulative Stressors in Europe
1999-2004 BMBF - MINCYT, Argentine, National University Argentine, La Plata
Airborne particles as risk factor for environmental diseases
National Projects
2007-2016 LINA-Lifestile and Environmental factors and their impact on newborne allergy risk
2002-2008 LISA - Influences of Lifestyle-Related Factors on the Immune System and the Development of Allergies in Childhood study
2004-2006 Esterspega Analysis in Environmental Medicine in Erfurt
1999-2008 LEIPI – Study of indoor mold in Leipzig

Publications

2019 (1)

2017 (1)

  • Escher, B.I., Hackermüller, J., Polte, T., Scholz, S., Aigner, A., Altenburger, R., Böhme, A., Bopp, S.K., Brack, W., Busch, W., Chadeau-Hyam, M., Covaci, A., Eisenträger, A., Galligan, J.J., Garcia-Reyero, N., Hartung, T., Hein, M., Herberth, G., Jahnke, A., Kleinjans, J., Klüver, N., Krauss, M., Lamoree, M., Lehmann, I., Luckenbach, T., Miller, G.W., Müller, A., Phillips, D.H., Reemtsma, T., Rolle-Kampczyk, U., Schüürmann, G., Schwikowski, B., Tan, Y.-M., Trump, S., Walter-Rohde, S., Wambaugh, J.F., (2017):
    From the exposome to mechanistic understanding of chemical-induced adverse effects
    Environ. Int. 99 , 97 - 106
    full text (doi)

2016 (2)

2015 (2)

2014 (1)

2013 (1)

2012 (1)

2011 (7)

2010 (1)

2009 (6)

2008 (5)

2007 (3)

2006 (4)

2005 (3)

2004 (1)

2003 (3)

2002 (5)

2001 (11)

2000 (11)

1999 (8)

1998 (4)

1997 (3)