Matthias Klös

Contact

Matthias Klös

Guest Scientist

Department of Environmental Immunology
Helmholtz Centre for Environmental Research – UFZ
Permoserstr. 15
04318 Leipzig
Germany

Tel: +49 341 235-1542
Fax: +49 341 235-1787

Matthias Klös
Photo: Sebastian Wiedling/UFZ

Research Interests

  • Epigenetic mechanisms of asthma development in early childhood
  • Environmental influences on methylation patterns in lung diseases

Curriculum vitae / Scientific career

10/2008 - 09/2011

Student of Nutrition and Food Sciences, Friedrich-Wilhelm University, Bonn, Bachelor of Science

10/2011 - 10/2014

Student of Nutritional Sciences, Martin-Luther-University Halle-Wittenberg, Faculty of Natural Sciences III, Institute for Agricultural and Nutritional Sciences, Halle, Master of Science

Master thesis, JRG Functional Genetics (Dr. Y. Böttcher), Integrated Research and Treatment Center (IFB) AdiposityDiseases, Leipzig:

“Differential Methylation of the candidate gene SSPN in human subcutaneous and visceral adipose tissue”

02/2013 - 04/2013

Research internship (MS Pro), Integrated Research and Treatment Center (IFB) Adiposity Diseases, Leipzig

02/2014 - 05/2014

Research assistant, Leipzig University, Integrated Research and Treatment Center (IFB) AdiposityDiseases, Leipzig

11/2014 - 01/2018

PhD student at the Department of Environmental Immunology at the Helmholtz Centre for Environmental Research - UFZ, Leipzig, Germany

Thesis: “Role of epigenetic mechanisms of asthma development and other lung diseases in early childhood and identification of biomarkers for the diagnostic investigation”


Publications

Rohde K, Keller M, Klös M, Schleinitz D, Dietrich A, Schön MR, Gärtner D, Lohmann T, Dreßler M, Stumvoll M, Kovacs P, Blüher M, Böttcher Y (2014). "Adipose tissue depot specific promoter methylation of TMEM18." J Mol Med (Berl) 92(8): 881-888

Index:

2018 (2)
2017 (1)

You could use our publication index for further requests.

2018 (2)

  • Keller, M., Klös, M., Rohde, K., Krüger, J., Kurze, T., Dietrich, A., Schön, M.R., Gärtner, D., Lohmann, T., Dreßler, M., Stumvoll, M., Blüher, M., Kovacs, P., Böttcher, Y., (2018):
    DNA methylation of SSPN is linked to adipose tissue distribution and glucose metabolism
    Faseb J. 32 (12), 6898 - 6910
    full text (url)
  • Thürmann, L., Grützmann, K., Klös, M., Bieg, M., Winter, M., Polte, T., Bauer, T., Schick, M., Bewerunge-Hudler, M., Röder, S., Bauer, M., Wissenbach, D.K., Sack, U., Weichenhan, D., Mücke, O., Plass, C., Borte, M., von Bergen, M., Lehmann, I., Eils, R., Trump, S., (2018):
    Early-onset childhood atopic dermatitis is related to NLRP2 repression
    J. Allergy Clin. Immunol. 141 (4), 1482 - 1485.e16
    full text (url)
to index

2017 (1)

  • Trump, S., Klos, M., Gu, L., Bauer, T., Ishaque, N., Thurmann, L., Bieg, M., Bauer, M., Gu, Z., Borte, M., Mallm, J.-P., Roder, S., Herrmann, C., Rippe, K., Lehmann, I., Eils, R., (2017):
    Asthma development in early childhood is associated with enhancer reprogramming
    Am. J. Respir. Crit. Care Med. 195 , A4910
    full text (url)
to index