Dr. Irina Lehmann

Contact

Dr. Irina Lehmann

Head of the Department

Department of Environmental Immunology and Core Facility Studies
Helmholtz Centre for Environmental Research – UFZ
Permoserstr. 15
04318 Leipzig
Germany

Phone: +49 341 235-1216
Fax: +49 341 235-1787

Dr. Irina Lehmann

Research Interests

Research at the Lehmann group is focused on the impact of environmental exposure, in particular exposure to environmental chemicals, on immune regulatory pathways and resulting consequences for disease risk. We use prospective birth cohort studies to investigate the impact of environmental exposure on the development of the immune system in the fetal and early postnatal period and the consequences for disease risk later in children’s life. By considering the whole chain of events from individual exposure to effects on cellular and molecular level we try to obtain a mechanistic understanding on the impact of lifestyle & environmental factors on disease pathology. The identification of the key molecular events responsible for perturbation of regulatory pathways by environmental/chemical exposure gives us the opportunity to identify marker signatures suitable for early diagnostics and identification of risk groups for specific individual prevention measures as well as potential targets for specific therapeutic intervention.


Curriculum vitae / Scientific career

1982 - 1987

Biology, University of Leipzig (Diploma, first class)

09/1987 - 08/1991

Ph.D. study at University of Leipzig, Faculty of Biosciences; Specialization: Human physiology and immunology (Ph.D. in Immunology, first class; Dr. rer. nat.)

09/1991 - 05/1996

Research Associate Institute for Clinical Immunology and Transfusion Medicine, University of Leipzig

05/1996 - 03/2000

Assistant Professor, University of Leipzig

01/2000

Certificate “Consultant Immunologist” (with additional qualification for immunodiagnostics) of the DGfI (German Society for Immunology)

04/2000 - 10/2003

Head of Junior Scientist Group of Environmental Immunology

since 10/2003

Head of the Department of Environmental Immunology and Core Facility Studies, Helmholtz Centre for Environmental Research - UFZ, Leipzig

Personal Qualifications

2006 - 2013

Coordinator of the Research Network “From contaminant molecules to cellular response – systems quantification and predictive model development” in the Helmholtz Alliance of Systems Biology

since 2006

Principle Investigator (PI) of the LINA study (LINA – Impact of prenatal lifestyle factors and environmental exposure on newborns allergy risk; prospective mother-child-cohort)

since 2008

Coordinator of the UFZ Health research program

since 2009

Principle Investigator (PI) in the LISA cohort study (Multicenter prospective German cohort on lifestyle factors, immune system development and allergy)

Selected Publications

Bauer T, Trump S, Ishaque N, Thürmann L, Gu L, Bauer M, Bieg M, Gu Z, Weichenhan D, Mallm JP, Röder S, Herberth G, Takada E, Mücke O, Winter M, Junge KM, Grützmann K, Rolle-Kampczyk U, Wang Q, Lawerenz C, Borte M, Polte T, Schlesner M, Schanne M, Wiemann S, Geörg C, Stunnenberg HG, Plass C, Rippe K, Mizuguchi J, Herrmann C, Eils R@, Lehmann I@: Environment-induced epigenetic reprogramming in genomic regulatory elements in smoking mothers and their children. Molecular Systems Biology 12, 2016; doi: 10.15252/msb.20156520

Junge KM, Bauer T, Geissler S, Hirche F, Thürmann L, Bauer M, Trump S, Bieg M, Weichenhan D, Gu L, Mallm JP, Ishaque N, Mücke O, Röder S, Herberth G, Diez U, Borte M, Rippe K, Plass C, Hermann C, Stangl GI, Eils R, Lehmann I. Increased vitamin D levels at birth and in early infancy increase offspring allergy risk-evidence for involvement of epigenetic mechanisms. J Allergy Clin Immunol. 2015 Aug 15., pii: S0091-6749(15)00941-0. doi: 10.1016/j.jaci.2015.06.040

Polte T, Petzold S, Bertrand J, Schütze N, Hinz D, Simon JC, Lehmann I, Echtermeyer F, Pap T, and Averbeck M. Critical role for syndecan-4 in dendritic cell migration during development of allergic airway inflammation. Nature Communications 2015 Jul 13; 6:7554. doi: 10.1038/ncomms8554

Herberth G, Offenberg K, Rolle-Kampczyk U, Bauer M, Otto W, Röder S, Grützmann K, Sack U, Simon JC, Borte M, von Bergen M, Lehmann I, for the LINA study group. The inflammasome activity in newborns and infants depends on the metabolic state and is linked to respiratory diseases. J Allergy Clin Immunol 2015 Mar 7. pii: S0091-6749(15)00112-8. doi: 10.1016/j

Herberth G, Bauer M, Gasch M, Hinz D, Röder S, Olek S, Kohajda T, Rolle-Kampczyk U, von Bergen-Tomm M, Sack U, Borte M, Lehmann I, for the LINA study group. Maternal and cord blood miR-223 expression associates with prenatal tobacco smoke exposure and low Treg numbers. J Allergy Clin Immunol. 2014 Feb;133(2):543-550.e4. doi: 10.1016/j.jaci.2013.06.036

Jäger N, Schlesner M, Jones DTW, …,Lehmann I,.. Eils R: Hypermutation of the inactive X chromosome is a frequent event in cancer. Cell 2013, 155 1-15, 201. doi: 10.1016/j.cell.2013.09.042

Opitz CA, Litzenburger UM, Sahms F, Otti M, Tritschler I, Trump S, Schumacher T, Jestaed L, Schrenk D, Weller M, Jugold M, Guillemin GJ, Miller CL, Lutz C, Radlwimmer B, Lehmann I, von Deimling A, Wick1 W, Platten M. An endogenous ligand of the human aryl hydrocarbon receptor promotes tumor formation. Nature 2011 Oct 5;478(7368):197-203

Herberth G, Hinz D, Röder S, Schlink U, Sack U, Diez U, Borte M, Lehmann I. Maternal immune status in pregnancy is related to offspring's immune responses and atopy risk. Allergy 2011 66(8) 1065-1074

Romanos M, Tiesler CM, Koletzko S, Berdel D, von Berg A, Hoffmann B, Schaaf B, Herbarth O, Lehmann I, Bauer CP, Stach B, Gerlach M, Schulte-Körne G, Heinrich J. No cross-sectional and longitudinal association of ferritin and symptoms of attention-deficit-/hyperactivity disorder in a large population-based sample of children: results from the GINIplus and LISAplus studies. Atten Defic Hyperact Disord. 2013 Apr 13

Kohlboeck G, Sausenthaler S, Standl M, Koletzko S, Bauer CP, von Berg A, Berdel D, Krämer U, Schaaf B, Lehmann I, Herbarth O, Heinrich J. Food Intake, Diet Quality and Behavioral Problems in Children: Results from the GINI-plus/LISA-plus Studies. Ann Nutr Metab. 2012 Jun 1; 60(4):247-256

Kohlboeck G, Glaser C, Tiesler C, Demmelmair H, Standl M, Romanos M, Koletzko B, Lehmann I, Heinrich J; LISAplus Study Group. Effect of fatty acid status in cord blood serum on children's behavioral difficulties at 10 y of age: results from the LISAplus Study. Am J Clin Nutr. 2011 Dec; 94(6):1592-9

(@=senior authorship)


Publications

Index:

2014 (14)
2013 (18)
2012 (29)
2011 (23)
2010 (17)
2009 (10)
2008 (11)
2007 (12)
2006 (4)
2005 (3)
2004 (10)
2003 (5)
2002 (16)
2001 (19)
2000 (17)

You could use our publication index for further requests.

2014 (14)

  • Brüske, I., Standl, M., Weidinger, S., Klümper, C., Hoffmann, B., Schaaf, B., Herbarth, O., Lehmann, I., von Berg, A., Berdel, D., Bauer, C.P., Koletzko, S., Heinrich, J., (2014):
    Epidemiology of urticaria in infants and young children in Germany – Results from the German LISAplus and GINIplus Birth Cohort Studies
    Pediatr. Allergy Immunol. 25 (1), 36 - 42
    full text (url)
  • Franck, U., Weller, A., Röder, S.W., Herberth, G., Junge, K.M., Kohajda, T., von Bergen, M., Rolle-Kampczyk, U., Diez, U., Borte, M., Lehmann, I., (2014):
    Prenatal VOC exposure and redecoration are related to wheezing in early infancy
    Environ. Int. 73 , 393 - 401
    full text (url)
  • Gasch, M., Goroll, T., Bauer, M., Hinz, D., Schütze, N., Polte, T., Kesper, D., Simon, J.-C., Hackermüller, J., Lehmann, I., Herberth, G., (2014):
    Generation of IL-8 and IL-9 producing CD4+ T cells is affected by Th17 polarizing conditions and AHR ligands
    Mediat. Inflamm. , 182549
    full text (url)
  • Herberth, G., Bauer, M., Gasch, M., Hinz, D., Röder, S., Olek, S., Kohajda, T., Rolle-Kampczyk, U., von Bergen, M., Sack, U., Borte, M., Lehmann, I., (2014):
    Maternal and cord blood miR-223 expression associates with prenatal tobacco smoke exposure and low regulatory T-cell numbers
    J. Allergy Clin. Immunol. 133 (2), 543 - 550.e4
    full text (url)
  • Junge, K.M., Hörnig, F., Herberth, G., Röder, S., Kohajda, T., Rolle-Kampczyk, U., von Bergen, M., Borte, M., Simon, J.-C., Heroux, D., Denburg, J.A., Lehmann, I., (2014):
    The LINA cohort: cord blood eosinophil/basophil progenitors predict respiratory outcomes in early infancy
    Clin. Immunol. 152 (1-2), 68 - 76
    full text (url)
  • Kluemper, C., Kraemer, U., Roeder, S., Lehmann, I., Bauer, C.P., Berdel, D., von Berg, A., Borte, M., Filipiak-Pittroff, B., Heinrich, J., Herbarth, O., Hoffmann, U., Koletzko, S., Link, E., Schaaf, B., Hoffmann, B., (2014):
    Longitudinal and cross sectional assessment of allergic diseases and social influences differ: results from GINIplus and LISAplus
    Allergy 68 (Suppl. 99), 93 - 93
    full text (url)
  • Kohlboeck, G., Romanos, M., Teuner, C.M., Holle, R., Tiesler, C.M.T., Hoffmann, B., Schaaf, B., Lehmann, I., Herbarth, O., Koletzko, S., Bauer, C.-P., von Berg, A., Berdel, D., Heinrich, J., (2014):
    Healthcare use and costs associated with children’s behavior problems
    Eur. Child Adolesc. Psych. 23 (8), 701 - 714
    full text (url)
  • Kohlboeck, G., Romanos, M., Tiesler, C., Koletzko, S., Kratzsch, J., Thiery, J., Bauer, C.-P., von Berg, A., Berdel, D., Hoffmann, B., Schaaf, B., Lehmann, I., Herbarth, O., Heinrich, J., (2014):
    Peer problems are associated with elevated serum leptin levels in children
    Psychol. Med. 44 (2), 255 - 265
    full text (url)
  • Litzenburger, U.M., Opitz, C.A., Sahm, F., Rauschenbach, K.J., Trump, S., Winter, M., Ott, M., Ochs, K., Lutz, C., Liu, X., Anastasov, N., Lehmann, I., Höfer, T., von Deimling, A., Wick, W., Platten, M., (2014):
    Constitutive IDO expression in human cancer is sustained by an autocrine signaling loop involving IL-6, STAT3 and the AHR
    Oncotarget 5 (4), 1038 - 1051
  • Pei, Z., Flexeder, C., Fuertes, E., Standl, M., Buyken, A., Berdel, D., von Berg, A., Lehmann, I., Schaaf, B., Heinrich, J., (2014):
    Food intake and overweight in school-aged children in Germany: Results of the GINIplus and LISAplus studies
    Ann. Nutr. Metab. 64 (1), 60 - 70
    full text (url)
  • Pei, Z., Heinrich, J., Fuertes, E., Flexeder, C., Hoffmann, B., Lehmann, I., Schaaf, B., von Berg, A., Koletzko, S., (2014):
    Cesarean delivery and risk of childhood obesity
    J. Pediatr. 164 (5), 1068 - 1073.e2
    full text (url)
  • Petzold, S., Averbeck, M., Simon, J.C., Lehmann, I., Polte, T., (2014):
    Lifetime-dependent effects of bisphenol A on asthma development in an experimental mouse model
    PLOS One 9 (6), e100468
    full text (url)
  • Tischer, C., Lehmann, I., Schaaf, B., von Berg, A., Heinrich, J., (2014):
    Sleeping on animal skin in the first 3 months of life and development of asthma and allergy in later childhood
    Allergy 68 (Suppl. 99), 326 - 327
    full text (url)
  • Wawro, N., Heinrich, J., Thiering, E., Kratzsch, J., Schaaf, B., Hoffmann, B., Lehmann, I., Bauer, C.-P., Koletzko, S., von Berg, A., Berdel, D., Linseisen, J., (2014):
    Serum 25(OH)D concentrations and atopic diseases at age 10: results from the GINIplus and LISAplus birth cohort studies
    BMC Pediatr. 14 , art. 286
    full text (url)
to index

2013 (18)

  • Casas, L., Tiesler, C., Thiering, E., Brüske, I., Koletzko, S., Bauer, C.P., Wichmann, H.-E., von Berg, A., Berdel, D., Krämer, U., Schaaf, B., Lehmann, I., Herbarth, O., Sunyer, J., Heinrich, J., (2013):
    Indoor factors and behavioural problems in children: the GINIplus and LISAplus birth cohort studies
    Int. J. Hyg. Environ. Health. 216 (2), 146 - 154
    full text (url)
  • Czamara, D., Tiesler, C.M.T., Kohlböck, G., Berdel, D., Hoffmann, B., Bauer, C.-P., Koletzko, S., Schaaf, B., Lehmann, I., Herbarth, O., von Berg, A., Müller-Myhsok, B., Schulte-Körne, G., Heinrich, J., (2013):
    Children with ADHD Symptoms Have a Higher Risk for Reading, Spelling and Math Difficulties in the GINIplus and LISAplus Cohort Studies
    PLOS One 8 (5), e63859
    full text (url)
  • Fuertes, E., Standl, M., Cyrys, J., Berdel, D., von Berg, A., Bauer, C.-P., Krämer, U., Sugiri, D., Lehmann, I., Koletzko, S., Carlsten, C., Brauer, M., Heinrich, J., (2013):
    A longitudinal analysis of associations between traffic-related air pollution with asthma, allergies and sensitization in the GINIplus and LISAplus birth cohorts
    PeerJ 1 , e193
    full text (url)
  • Herberth, G., Bauer, M., Gasch, M., Hinz, D., Röder, S., Olek, S., Kohajda, T., Rolle-Kampczyk, U., von Bergen-Tomm, M., Sack, U., Borte, M., Lehmann, I., (2013):
    Maternal and cord blood miR-223 expression associates with prenatal tobacco smoke exposure and with low Treg numbers
    Allergy 68 (Suppl. 97), 628 - 628
    full text (url)
  • Herberth, G., Herzog, T., Hinz, D., Röder, S., Schilde, M., Sack, U., Diez, U., Borte, M., Lehmann, I., (2013):
    Renovation activities during pregnancy induce a Th2 shift in fetal but not in maternal immune system
    Int. J. Hyg. Environ. Health. 216 (3), 309 - 316
    full text (url)
  • Jäger, N., Schlesner, M., Jones, D.T.W., Raffel, S., Mallm, J.-P., Junge, K.M., Weichenhan, D., Bauer, T., Ishaque, N., Kool, M., Northcott, P.A., Korshunov, A., Drews, R.M., Koster, J., Versteeg, R., Richter, J., Hummel, M., Mack, S.C., Taylor, M.D., Witt, H., Swartman, B., Schulte-Bockholt, D., Sultan, M., Yaspo, M.-L., Lehrach, H., Hutter, B., Brors, B., Wolf, S., Plass, C., Siebert, R., Trumpp, A., Rippe, K., Lehmann, I., Lichter, P., Pfister, S.M., Eils, R., (2013):
    Hypermutation of the inactive X chromosome is a frequent event in cancer
    Cell 155 (3), 567 - 581
    full text (url)
  • Junge, K.M., Lehmann, I., Borte, M., (2013):
    Can vitamin D intake during pregnancy affect the risk of allergy in children?
    Expert Rev. Clin. Immunol. 9 (8), 699 - 701
    full text (url)
  • Kohlboeck, G., Koletzko, S., Bauer, C.-P., von Berg, A., Berdel, D., Krämer, U., Schaaf, B., Lehmann, I., Herbarth, O., Heinrich, J., (2013):
    Association of atopic and non-atopic asthma with emotional symptoms in school children
    Pediatr. Allergy Immunol. 24 (3), 230 - 236
    full text (url)
  • Mai, J., Trump, S., Lehmann, I., Attinger, S., (2013):
    Parameter importance in FRAP acquisition and analysis: a simulation approach
    Biophys. J. 104 (9), 2089 - 2097
    full text (url)
  • Murugaiyan, J., Rockstroh, M., Wagner, J., Baumann, S., Schorsch, K., Trump, S., Lehmann, I., von Bergen, M., Tomm, J.M., (2013):
    Benzo[a]pyrene affects Jurkat T cells in the activated state via the antioxidant response element dependent Nrf2 pathway leading to decreased IL-2 secretion and redirecting glutamine metabolism
    Toxicol. Appl. Pharmacol. 269 (3), 307 - 316
    full text (url)
  • Ortlieb, S., Schneider, G., Koletzko, S., Berdel, D., von Berg, A., Bauer, C.-P., Schaaf, B., Herbarth, O., Lehmann, I., Hoffmann, B., Heinrich, J., Schulz, H., (2013):
    Physical activity and its correlates in children: a cross-sectional study (the GINIplus & LISAplus studies)
    BMC Public Health 13 , art. 349
    full text (url)
  • Pei, Z., Flexeder, C., Fuertes, E., Thiering, E., Koletzko, B., Cramer, C., Berdel, D., Lehmann, I., Bauer, C.-P., Heinrich, J., (2013):
    Early life risk factors of being overweight at 10 years of age: results of the German birth cohorts GINIplus and LISAplus
    Eur. J. Clin. Nutr. 67 (8), 855 - 862
    full text (url)
  • Petzold, S., Averbeck, M., Simon, J.-C., Lehmann, I., Polte, T., (2013):
    Phthalates and bisphenol A may increase asthma severity in mice depending on the exposure period
    Allergy 68 (Suppl. 97), 176 - 176
    full text (url)
  • Querfeld, U., Keil, T., Beyer, K., Stock, P., Pilz, S., März, W., Weisse, K., Lehmann, I., (2013):
    Vitamin D in early life: good or bad for food allergies?
    Allergy 68 (8), 1081 - 1083
    full text (url)
  • Reiprich, M., Rudzok, S., Schütze, N., Simon, J.C., Lehmann, I., Trump, S., Polte, T., (2013):
    Inhibition of endotoxin-induced perinatal asthma protection by pollutants in an experimental mouse model
    Allergy 68 (4), 481 - 489
    full text (url)
  • Romanos, M., Tiesler, C.M.T., Koletzko, S., Berdel, D., von Berg, A., Hoffmann, B., Schaaf, B., Herbarth, O., Lehmann, I., Bauer, C.-P., Stach, B., Gerlach, M., Schulte-Körne, G., Heinrich, J., (2013):
    No cross-sectional and longitudinal association of ferritin and symptoms of attention-deficit-/hyperactivity disorder in a large population-based sample of children: results from the GINIplus and LISAplus studies
    ADHD Attention Deficit and Hyperactivity Disorders 5 (3), 313 - 320
    full text (url)
  • Weisse, K., Herberth, G., Röder, S., Borte, M., Heroux, D., Denburg, J., Lehmann, I., (2013):
    Eosinophil/basophil (Eo/B) progenitors in cord blood (CB) predict respiratory outcomes in early infancy
    Allergy 68 (Suppl. 97), 53 - 53
    full text (url)
  • Weisse, K., Winkler, S., Hirche, F., Herberth, G., Hinz, D., Bauer, M., Röder, S., Rolle-Kampczyk, U., von Bergen, M., Olek, S., Richter, T., Diez, U., Borte, M., Stangl, G.I., Lehmann, I., (2013):
    Maternal and newborn vitamin D status and its impact on food allergy development in the German LINA cohort study
    Allergy 68 (2), 220 - 228
    full text (url)
to index

2012 (29)

  • Batscheider, A., Zakrzewska, S., Heinrich, J., Teuner, C.M., Menn, P., Bauer, C.P., Hoffmann, U., Koletzko, S., Lehmann, I., Herbarth, O., von Berg, A., Berdel, D., Krämer, U., Schaaf, B., Wichmann, H.-E., Leidl, R., (2012):
    Exposure to second-hand smoke and direct healthcare costs in children – results from two German birth cohorts, GINIplus and LISAplus
    BMC Health Serv. Res. 12 , art 344
    full text (url)
  • Bauer, M., Gräbsch, C., Schlink, U., Klopp, N., Illig, T., Krämer, U., von Berg, A., Schaaf, B., Borte, M., Heinrich, J., Herbarth, O., Lehmann, I., Röder, S., (2012):
    Genetic association between obstructive bronchitis and enzymes of oxidative stress
    Metab.-Clin. Exp. 61 (12), 1771 - 1779
    full text (url)
  • Bönisch, U., Böhme, A., Kohajda, T., Mögel, I., Schütze, N., von Bergen, M., Simon, J.C., Lehmann, I., Polte, T., (2012):
    Volatile organic compounds enhance allergic airway inflammation in an experimental mouse model
    PLoS One 7 (7), e39817
    full text (url)
  • Casas, L., Tischer, C., Tiesler, C., Brüske, I., Koletzko, S., Bauer, C.P., Wichmann, H.-E., von Berg, A., Berdel, D., Krämer, U., Schaaf, B., Lehmann, I., Herbarth, O., Heinrich, J., (2012):
    Association of gas cooking with children's respiratory health: results from GINIplus and LISAplus birth cohort studies
    Indoor Air 22 (6), 476 - 482
    full text (url)
  • Cramer, C., Link, E., Koletzko, S., Lehmann, I., Heinrich, J., Wichmann, H.-E., Bauer, C.P., von Berg, A., Berdel, D., Herbarth, O., Schaaf, B., Borte, M., Behrendt, H., Krämer, U., (2012):
    The hygiene hypothesis does not apply to atopic eczema in childhood
    In: Ring, J., Darsow, U., Behrendt, H., (eds.)
    New trends in allergy and atopic eczema
    Chemical Immunology and Allergy 96
    Karger, Basel, p. 15 - 23
    full text (url)
  • Filipiak-Pittroff, B., Schnopp, C., Rodriguez, E., Berdel, D., Naumann, A., Sedlmeier, S., Onken, A.T., Foelster-Holst, R., Baurecht, H., Ollert, M., Ring, J., Cramer, C., von Berg, A., Bauer, C.-P., Herbarth, O., Lehmann, I., Schaaf, B., Koletzko, S., Wichmann, H.E., Heinrich, J., Weidinger, S., (2012):
    Predictive value of food sensitization and filaggrin mutations in children with eczema
    Exp. Dermatol. 21 (3), e21
    full text (url)
  • Flexeder, C., Thiering, E., Brüske, I., Koletzko, S., Bauer, C.P., Wichmann, H.-E., Mansmann, U., von Berg, A., Berdel, D., Krämer, U., Schaaf, B., Lehmann, I., Herbarth, O., Heinrich, J., (2012):
    Growth velocity during infancy and onset of asthma in school-aged children
    Allergy 67 (2), 257 - 264
    full text (url)
  • Franck, U., Krüger, M., Schwarz, N., Großmann, K., Lehmann, I., Röder, S., Schlink, U., (2012):
    Heat stress in urban areas: indoor and outdoor temperatures in different types of housing areas in the city of Leipzig and subjectively reported well-being
    In: Raabe, A., (Hrsg.)
    METTOOLS VIII - Tagungsband : 20.03.2012 - 22.03.2012 ; [an der Universität Leipzig ; eine Tagung des Fachausschusses Umweltmeteorologie FAUMET der Deutschen Meteorologischen Gesellschaft DMG e.V.]
    Wissenschaftliche Mitteilungen aus dem Institut für Meteorologie der Universität Leipzig 49
    Universität Leipzig, Institut für Meteorologie, Leipzig, S. 107 - 108
  • Franck, U., Röder, S., Schlink, U., Borte, M., Herbarth, O., Lehmann, I., (2012):
    Most relevant sources of indoor particles in children’s rooms and respiratory health effects of size-segregated particles
    In: Longhurst, J.W.S., Brebbia, C.A., (eds.)
    Air pollution XX
    WIT Transactions on Ecology and the Environment 157
    WIT Press, Southampton, p. 457 - 468
    full text (url)
  • Heinrich, J., Brueske, I., Cramer, C., Hoffmann, U., Schnappinger, M., Schaaf, B., von Berg, A., Berdel, D., Kraemer, U., Lehmann, I., Herbarth, O., Borte, M., Grübl, A., Bauer, C., Beckmann, C., Behrendt, H., Ring, J., Koletzko, S., (2012):
    GINIplus und LISAplus. Design und ausgewählte Ergebnisse zweier deutscher Geburtskohorten zum natürlichen Verlauf atopischer Erkrankungen sowie deren Determinanten. GINIplus and LISAplus. Design and selected results of two German birth cohorts about natural course of atopic diseases and its determinants
    Allergologie 35 (1), 20 - 31
    full text (url)
  • Heinrich, J., Brüske, I., Schnappinger, M., Standl, M., Flexeder, C., Thiering, E., Tischer, C., Tiesler, C.M.T., Wenig, C.M., Bauer, C.P., Schaaf, B., von Berg, A., Berdel, D., Krämer, U., Cramer, C., Lehmann, I., Herbarth, O., Behrendt, H., Ring, J., Kühnisch, J., Koletzko, S., (2012):
    Die zwei deutschen Geburtskohorten GINIplus und LISAplus. Two German Birth Cohorts: GINIplus and LISAplus
    Bundesgesundheitsblatt-Gesund. 55 (6-7), 864 - 874
    full text (url)
  • Herberth, G., Hinz, D., Bauer, M., Röder, S., Olek, S., Huehn, J., Sack, U., Borte, M., Simon, J., Lehmann, I., (2012):
    Exposures during pregnancy modulate foetal regulatory T-cell development with consequences for the allergy risk of the child
    Allergy 67 (Suppl. 96), 65 - 65
    full text (url)
  • Herberth, G., Hinz, D., Bauer, M., Röder, S., Olek, S., Hühn, J., Sack, U., Borte, M., Simon, J.C., Lehmann, I., (2012):
    Environmental exposure during pregnancy modulates fetal Treg development with consequences for the allergy risk of the child
    J. Immunol. 188 (Suppl.), 175.10
  • Herberth, G., Hinz, D., Bauer, M., Röder, S., Olek, S., Hühn, J., Sack, U., Borte, M., Simon, J.C., Lehmann, I., (2012):
    Environmental exposure during pregnancy modulates fetal Treg development with consequences for the allergy risk of the child
    J. Reprod. Immunol. 94 (1), 54 - 54
    full text (url)
  • Hinz, D., Bauer, M., Röder, S., Olek, S., Huehn, J., Sack, U., Borte, M., Simon, J.C., Herberth, G., Lehmann, I., (2012):
    Lower treg number in cord blood is associated with significant increased risk against atopic dermatitis up to the second year of life
    Eur. J. Epidemiol. 27 (Suppl. 1), S104
    full text (url)
  • Hinz, D., Bauer, M., Röder, S., Olek, S., Huehn, J., Sack, U., Borte, M., Simon, J.C., Lehmann, I., Herberth, G., (2012):
    Cord blood Tregs with stable FOXP3 expression are influenced by prenatal environment and associated with atopic dermatitis at the age of one year
    Allergy 67 (3), 380 - 389
    full text (url)
  • Hörnig, F., Weisse, K., Röder, S., Kohajda, T., von Bergen-Tomm, M., Borte, M., Diez, U., Simon, J., Denburg, J., Lehmann, I., (2012):
    Infantile eosinophil/basophil progenitors are more sensitive to indoor chemical exposures compared to their mothers
    Allergy 67 (Suppl. 96), 574 - 574
    full text (url)
  • Italia, S., Batscheider, A., Heinrich, J., Wenig, C., Bauer, C.P., Koletzko, S., Lehmann, I., Herbarth, O., von Berg, A., Berdel, D., Hoffmann, B., Schaaf, B., Wolfenstetter, S.B., (2012):
    Utilization and costs of conventional and alternative pharmaceuticals in children: results from the German GINIplus and LISAplus birth cohort studies
    Pharmacoepidemiol. Drug Saf. 21 (10), 1102 - 1111
    full text (url)
  • Kohlboeck, G., Sausenthaler, S., Standl, M., Koletzko, S., Bauer, C.-P., von Berg, A., Berdel, D., Krämer, U., Schaaf, B., Lehmann, I., Herbarth, O., Heinrich, J., (2012):
    Food intake, diet quality and behavioral problems in children: results from the GINI-plus/LISA-plus studies
    Ann. Nutr. Metab. 60 (4), 247 - 256
    full text (url)
  • Lehmann, I., Herberth, G., (2012):
    Cord blood immune status: predicting health or allergy?
    Allergy 67 (4), 445 - 448
    full text (url)
  • Lehmann, I., Weiße, K., (2012):
    Rauchen beeinflusst allergierelevante Stammzellen
    Pneumologie 66 (12), 702
  • Leitte, A.M., Schlink, U., Wiedensohler, A., Pan, X.C., Hu, M., Wehner, B., Breitner, S., Peters, A., Herbarth, O., Wichmann, E., Lehmann, I., Franck, U., (2012):
    Size-segregated airborne particles and respiratory mortality in Beijing, China
    In: Singh, V., Price, H., Bartzis, J., Sokhi, R.S., (eds.)
    Proceedings 8th International Conference on Air Quality Science and Application, Athens, 19-23 March 2012
    University of Hertfordshire, Hatfield, p. 44
  • Rösch, C., Schlink, U., Röder, S., Kohajda, T., Franck, U., Thiem, A., Lehmann, I., (2012):
    VOC-Muster in Leipziger Innenräumen
    In: Raabe, A., (Hrsg.)
    METTOOLS VIII - Tagungsband : 20.03.2012 - 22.03.2012 ; [an der Universität Leipzig ; eine Tagung des Fachausschusses Umweltmeteorologie FAUMET der Deutschen Meteorologischen Gesellschaft DMG e.V.]
    Wissenschaftliche Mitteilungen aus dem Institut für Meteorologie der Universität Leipzig 49
    Universität Leipzig, Institut für Meteorologie, Leipzig, S. 50 - 51
  • Schlink, U., Röder, S., Takacs, S., Kohajda, T., Franck, U., Thiem, A., Rösch, C., Lehmann, I., (2012):
    Volatile Organic Compounds in the indoor air of occupied apartments
    In: Raabe, A., (ed.)
    METTOOLS VIII - Tagungsband : 20.03.2012 - 22.03.2012 ; [an der Universität Leipzig ; eine Tagung des Fachausschusses Umweltmeteorologie FAUMET der Deutschen Meteorologischen Gesellschaft DMG e.V.]
    Wissenschaftliche Mitteilungen aus dem Institut für Meteorologie der Universität Leipzig 49
    Universität Leipzig, Institut für Meteorologie, Leipzig, p. 37 - 38
  • Standl, M., Sausenthaler, S., Lattka, E., Koletzko, S., Bauer, C.P., Wichmann, H.-E., von Berg, A., Berdel, D., Krämer, U., Schaaf, B., Lehmann, I., Herbarth, O., Klopp, N., Koletzko, B., Heinrich, J., (2012):
    FADS gene cluster modulates the effect of breastfeeding on asthma. Results from the GINIplus and LISAplus studies
    Allergy 67 (1), 83 - 90
    full text (url)
  • Weisse, K., Herberth, G., Roeder, S., Borte, M., Heroux, D., Denburg, J.A., Lehmann, I., (2012):
    Cord blood (CB) eosinophil/basophil (Eo/B) progenitors predict respiratory outcomes until the age of two
    J. Allergy Clin. Immunol. 129 (2, Suppl.), AB118 - AB118
    full text (url)
  • Weisse, K., Lehmann, I., Heroux, D., Kohajda, T., Herberth, G., Röder, S., von Bergen, M., Borte, M., Denburg, J., (2012):
    The LINA cohort: indoor chemical exposure, circulating eosinophil/basophil (Eo/B) progenitors and early life skin manifestations
    Clin. Exp. Allergy 42 (9), 1337 - 1346
    full text (url)
  • Weisse, K., Winkler, S., Stangl, G., Hirche, F., Herberth, G., Hinz, D., Röder, S., Borte, M., Richter, T., Lehmann, I., (2012):
    Maternal and newborn vitamin D status and its impact on atopy development in the German LINA cohort study
    Allergy 67 (Suppl. 96), 201 - 201
    full text (url)
  • Weisse, K., Winkler, S., Stangl, G.I., Hirche, F., Herberth, G., Hinz, D., Bauer, M., Röder, S., Rolle-Kampczyk, U., von Bergen-Tomm, M., Olek, S., Sack, U., Borte, M., Richter, T., Lehmann, I., (2012):
    Maternal and newborn vitamin D status and its impact on fetal regulatory T cell development and children's atopy risk in the German LINA cohort study
    J. Reprod. Immunol. 94 (1), 53 - 54
    full text (url)
to index

2011 (23)

  • Busch, W., Bastian, S., Trahorsch, U., Iwe, M., Kühnel, D., Meißner, T., Springer, A., Gelinsky, M., Richter, V., Ikonomidou, C., Potthoff, A., Lehmann, I., Schirmer, K., (2011):
    Internalisation of engineered nanoparticles into mammalian cells in vitro: influence of cell type and particle properties
    J. Nanopart. Res. 13 (1), 293 - 310
    full text (url)
  • Cramer, C., Link, E., Bauer, C.P., Hoffmann, U., von Berg, A., Lehmann, I., Herbarth, O., Borte, M., Schaaf, B., Sausenthaler, S., Wichmann, H.-E., Heinrich, J., Krämer, U., (2011):
    Association between attendance of day care centres and increased prevalence of eczema in the German birth cohort study LISAplus
    Allergy 66 (1), 68 - 75
    full text (url)
  • Dautel, F., Kalkhof, S., Trump, S., Lehmann, I., Beyer, A., von Bergen, M., (2011):
    Large-scale 2-D DIGE studies - guidelines to overcome pitfalls and challenges along the experimental procedure
    Journal of Integrated OMICS 1 (1), 170 - 179
    full text (url)
  • Dautel, F., Kalkhof, S., Trump, S., Michaelson, J., Beyer, A., Lehmann, I., von Bergen, M., (2011):
    DIGE-based protein expression analysis of B[a]P-exposed hepatoma cells reveals a complex stress response including alterations in oxidative stress, cell cycle control, and cytoskeleton motility at toxic and subacute concentrations
    J. Proteome Res. 10 (2), 379 - 393
    full text (url)
  • Filipiak-Pittroff, B., Schnopp, C., Berdel, D., Naumann, A., Sedlmeier, S., Onken, A., Rodriguez, E., Foelster-Holst, R., Baurecht, H., Ollert, M., Ring, J., Cramer, C., von Berg, A., Bauer, C.P., Herbarth, O., Lehmann, I., Schaaf, B., Koletzko, S., Wichmann, H.-E., Heinrich, J., Weidinger, S., (2011):
    Predictive value of food sensitization and filaggrin mutations in children with eczema
    J. Allergy Clin. Immunol. 128 (6), 1235 - 1241.e5
    full text (url)
  • Franck, U., Herbarth, O., Röder, S., Schlink, U., Borte, M., Diez, U., Krämer, U., Lehmann, I., (2011):
    Respiratory effects of indoor particles in young children are size dependent
    Sci. Total Environ. 409 (9), 1621 - 1631
    full text (url)
  • Goodman, V., Müller, A., Gröger-Arndt, H., Schlosser, D., Jehmlich, N., Treudler, R., Lehmann, I., Simon, J.-C., von Bergen, M., (2011):
    Identification of spore specific allergen candidates from Penicillium chrysogenum
    Journal of Integrated OMICS 1 (2), 272 - 279
    full text (url)
  • Herberth, G., Hinz, D., Röder, S., Schlink, U., Sack, U., Diez, U., Borte, M., Lehmann, I., (2011):
    Maternal immune status in pregnancy: relation to offspring's immunity and allergy risk
    Allergy 66 (S94), 187 - 1074
    full text (url)
  • Herberth, G., Hinz, D., Röder, S., Schlink, U., Sack, U., Diez, U., Borte, M., Lehmann, I., (2011):
    Maternal immune status in pregnancy is related to offspring's immune responses and atopy risk
    Allergy 66 (8), 1065 - 1074
    full text (url)
  • Kohlboeck, G., Glaser, C., Tiesler, C., Demmelmair, H., Standl, M., Romanos, M., Koletzko, B., Lehmann, I., Heinrich, J., (2011):
    Effect of fatty acid status in cord blood serum on children's behavioral difficulties at 10 y of age: results from the LISAplus Study
    Am. J. Clin. Nutr. 94 (6), 1592 - 1599
    full text (url)
  • Kruber, P., Trump, S., Behrens, J., Lehmann, I., (2011):
    T-2 toxin is a cytochrome P450 1A1 inducer and leads to MAPK/p38- but not aryl hydrocarbon receptor-dependent interleukin-8 secretion in the human intestinal epithelial cell line Caco-2
    Toxicology 284 (1-3), 34 - 41
    full text (url)
  • Lehmann, I., Sack, U., Lehmann, J., (2011):
    Metal ions affecting the immune system
    In: Sigel, A., Sigel, H., Sigel, R.K.O., (eds.)
    Metal ions in toxicology: effects, interactions, interdependencies
    Metal Ions in Life Sciences 8
    Royal Society of Chemistry (RSC), Cambridge, p. 157 - 186
    full text (url)
  • Mai, J., Trump, S., Ali, R., Schiltz, R.L., Hager, G., Hanke, T., Lehmann, I., Attinger, S., (2011):
    Are assumptions about the model type necessary in reaction-diffusion modeling? A FRAP application
    Biophys. J. 100 (5), 1178 - 1188
    full text (url)
  • Michaelson, J., Trump, S., Rudzok, S., Gräbsch, C., Madureira, D.J., Dautel, F., Mai, J., Attinger, S., Schirmer, K., von Bergen, M., Lehmann, I., Beyer, A., (2011):
    Transcriptional signatures of regulatory and toxic responses to benzo-[a]-pyrene exposure
    BMC Genomics 12 , art. 502
    full text (url)
  • Mögel, I., Baumann, S., Böhme, A., Kohajda, T., von Bergen, M., Simon, J.-C., Lehmann, I., (2011):
    The aromatic volatile organic compounds toluene, benzene and styrene induce COX-2 and prostaglandins in human lung epithelial cells via oxidative stress and p38 MAPK activation
    Toxicology 289 (1), 28 - 37
    full text (url)
  • Mörbt, N., Feltens, R., Tomm, J., Kalkhof, S., Mögel, I., Vogt, C., Lehmann, I., von Bergen, M., (2011):
    Chlorinated benzenes cause concomitantly oxidative stress and induction of apoptotic markers in lung epithelial cells (A549) at non-acute toxic concentrations
    J. Proteome Res. 10 (2), 363 - 378
    full text (url)
  • Opitz, C.A., Litzenburger, U.M., Sahm, F., Ott, M., Tritschler, I., Trump, S., Schumacher, T., Jestaedt, L., Schrenk, D., Weller, M., Jugold, M., Guillemin, G.J., Miller, C.L., Lutz, C., Radlwimmer, B., Lehmann, I., von Deimling, A., Wick, W., Platten, M., (2011):
    An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor
    Nature 478 (7368), 197 - 203
    full text (url)
  • Sausenthaler, S., Standl, M., Buyken, A., Rzehak, P., Koletzko, S., Bauer, C.P., Schaaf, B., von Berg, A., Berdel, D., Borte, M., Herbarth, O., Lehmann, I., Krämer, U., Wichmann, H.-E., Heinrich, J., (2011):
    Regional and socio-economic differences in food, nutrient and supplement intake in school-age children in Germany: results from the GINIplus and the LISAplus studies
    Public Health Nutr. 14 (10), 1724 - 1735
    full text (url)
  • Schmitt, J., Chen, C.M., Apfelbacher, C., Romanos, M., Lehmann, I., Herbarth, O., Schaaf, B., Kraemer, U., von Bergen, M., Wichmann, H.-E., Heinrich, J., (2011):
    Infant eczema, infant sleeping problems, and mental health at 10 years of age: the prospective birth-cohort study LISAplus
    Allergy 66 (3), 404 - 411
    full text (url)
  • Thiering, E., Brüske, I., Kratzsch, J., Thiery, J., Sausenthaler, S., Meisinger, C., Koletzko, S., Bauer, C.P., Schaaf, B., von Berg, A., Berdel, D., Lehmann, I., Herbarth, O., Krämer, U., Wichmann, H.-E., Heinrich, J., (2011):
    Prenatal and postnatal tobacco smoke exposure and development of insulin resistance in 10 year old children
    Int.J.Hyg.Environ.Health 214 (5), 361 - 368
    full text (url)
  • Tiesler, C.M.T., Chen, C.-M., Sausenthaler, S., Herbarth, O., Lehmann, I., Schaaf, B., Krämer, U., von Berg, A., von Kries, R., Wichmann, H.-E., Heinrich, J., (2011):
    Passive smoking and behavioural problems in children: Results from the LISAplus prospective birth cohort study
    Environ. Res. 111 (8), 1173 - 1179
    full text (url)
  • Tischer, C., Gehring, U., Chen, C.M., Kerkhof, M., Koppelman, G., Sausenthaler, S., Herbarth, O., Schaaf, B., Lehmann, I., Krämer, U., Berdel, D., von Berg, A., Bauer, C.P., Koletzko, S., Wichmann, H.-E., Brunekreef, B., Heinrich, J., (2011):
    Respiratory health in children, and indoor exposure to (1,3)-β-D-glucan, EPS mould components and endotoxin
    Eur. Resp. J. 37 (5), 1050 - 1059
    full text (url)
  • Weisse, K., Lehmann, I., Herberth, G., Kohajda, T., Röder, S., Borte, M., Heroux, A., Denburg, J., (2011):
    Circulating eosinophil/basophil (Eo/B) progenitors at one year of age positively correlate with atopic eczema and indoor chemical exposure in the LINA Study
    J. Allergy Clin. Immunol. 127 (2), AB146 - AB146
    full text (url)
to index

2010 (17)

  • Bönisch, U., Lehmann, I., Kohajda, T., Simon, J., Polte, T., (2010):
    Volatile organic compounds enhance airway inflammation and IgE levels in a murine asthma model
    Allergy 65 (S92), 85 - 86
    full text (url)
  • Cramer, C., Link, E., Horster, M., Koletzko, S., Bauer, C., Berdel, D., von Berg, A., Lehmann, I., Herbarth, O., Borte, M., Schaaf, B., Behrendt, H., Chen, C., Sausenthaler, S., Illig, T., Wichmann, H., Heinrich, J., Ursula, K., (2010):
    Limits of the hygiene-hypothesis: elder siblings enhance the effect of filaggrin mutations on childhood eczema - results from the LISAplus and GINIplus study
    Allergy 65 (S92), 47 - 48
    full text (url)
  • Cramer, C., Link, E., Horster, M., Koletzko, S., Bauer, C.P., Berdel, D., von Berg, A., Lehmann, I., Herbarth, O., Borte, M., Schaaf, B., Behrendt, H., Chen, C.-M., Sausenthaler, S., Illig, T., Wichmann, H.-E., Heinrich, J., Krämer, U., (2010):
    Elder siblings enhance the effect of filaggrin mutations on childhood eczema: results from the 2 birth cohort studies LISAplus and GINIplus
    J. Allergy Clin. Immunol. 125 (6), 1254 - 1260
    full text (url)
  • Feltens, R., Mögel, I., Röder-Stolinski, C., Simon, J.-C., Herberth, G., Lehmann, I., (2010):
    Chlorobenzene induces oxidative stress in human lung epithelial cells in vitro
    Toxicol. Appl. Pharmacol. 242 (1), 100 - 108
    full text (url)
  • Herberth, G., Daegelmann, C., Röder, S., Behrendt, H., Krämer, U., Borte, M., Heinrich, J., Herbarth, O., Lehmann, I., (2010):
    IL-17E but not IL-17A is associated with allergic sensitization: results from the LISA study
    Pediatr. Allergy Immunol. 21 (7), 1086 - 1090
    full text (url)
  • Herberth, G., Heinrich, J., Röder, S., Figl, A., Weiss, M., Diez, U., Borte, M., Herbarth, O., Lehmann, I., (2010):
    Reduced IFN-y- and enhanced IL-4-producing CD4+ cord blood T cells are associated with a higher risk for atopic dermatitis during the first 2 yr of life
    Pediatr. Allergy Immunol. 21 (1, Part-I), 5 - 13
    full text (url)
  • Herberth, G., Hinz, D., Roeder, S., Schlink, U., Diez, U., Borte, M., Lehmann, I., (2010):
    Innate versus adaptive immune response in newborns and their mothers: results from the LINA birth cohort study
    Allergy 65 (S92), 645 - 646
    full text (url)
  • Herberth, G., Röder, S., Bockelbrink, T., Schäfer, T., Borte, M., Herbarth, O., Krämer, U., Behrendt, H., Sausenthaler, S., Heinrich, J., Lehmann, I., (2010):
    Psychosozialer Stress im Kindesalter und allergische Sensibilisierung. Stressful life events in childhood and allergic sensitisation
    Allergologie 33 (2), 55 - 65
    full text (url)
  • Hinz, D., Simon, J.C., Maier-Simon, C., Milkova, L., Röder, S., Sack, U., Borte, M., Lehmann, I., Herberth, G., (2010):
    Reduced maternal regulatory T cell numbers and increased T helper type 2 cytokine production are associated with elevated levels of immunoglobulin E in cord blood
    Clin. Exp. Allergy 40 (3), 419 - 426
    full text (url)
  • Hinz, D., Simon, J., Maier-Simon, C., Milkova, L., Roeder, S., Sack, U., Borte, M., Lehmann, I., Herberth, G., (2010):
    The impact of maternal CD4+CD25high T cell numbers and Th2 cytokine production during pregnancy on IgE in cord blood
    Allergy 65 (S92), 315 - 315
    full text (url)
  • Lehmann, I., Herzog, T., Hinz, D., Roeder, S., Sack, U., Diez, U., Borte, M., Herberth, G., (2010):
    Renovation activities during pregnancy induce a Th2 shift in the fetal but not in the maternal immune system
    Allergy 65 (S92), 306 - 307
    full text (url)
  • Mögel, I., Feltens, R., Simon, J., Röder-Stolinski, C., Herberth, G., Lehmann, I., (2010):
    The chlorobenzene induced inflammatory response in lung epithelial cells can be prevented by antioxidants
    Allergy 65 (S92), 86 - 87
    full text (url)
  • Rzehak, P., Scherag, A., Grallert, H., Sausenthaler, S., Koletzko, S., Bauer, C.P., Schaaf, B., von Berg, A., Berdel, D., Borte, M., Herbarth, O., Krämer, U., Illig, T., Wichmann, H.-E., Hebebrand, J., Heinrich, J., Schoetzau, A., Popescu, M., Mosetter, M., Schindler, J., Franke, K., Laubereau, B., Thaqi, A., Zirngibl, A., Zutavern, A., Filipiak, B., Gehring, U., Albrecht, B., Baumgart, A., Bollrath, C., Büttner, S., Diekamp, S., Gross, I., Jakob, T., Klemke, K.K., Kurpiun, K.S., Möllermann, M., Neusüss, J., Varhelyi, A., Zorn, C., Reinhard, D., Weigand, H., Antonie, I., Bäumler-Merl, B., Tasch, C., Göhlert, R., Sönnichsen, C., Grübl, A., Bartels, P., Brockow, I., Hoffmann, U., Lötzbeyer, F., Mayrl, R., Negele, K., Schill, E.M., Wolf, B., Link, E., Sugiri, D., Ranft, U., Bolte, G., Belcredi, P., Jacob, B., Höhnke, A., Schulz, R., Sierig, G., Mirow, K., Gebauer, C., Schulze, B., Hainich, J., Sack, U., Emmrich, F., Scholten, C., Diez, U., Rehwagen, M., Schlink, U., Franck, U., Jorks, A., Röder, S., Lehmann, I., Herberth, G., Daegelmann, C., Weiss, M., Albert, M., Fahlbusch, B., Bischof, W., Koch, A., Schins, R., Ring, J., Grosch, J., Weidinger, S., (2010):
    Associations between BMI and the FTO gene are age dependent: results from the GINI and LISA birth cohort studies up to age 6 years
    Obes. Facts 3 (3), 173 - 180
    full text (url)
  • Rzehak, P., Thijs, C., Standl, M., Mommers, M., Glaeser, C., Jansen, E., Klopp, N., Koppelman, G.H., Singmann, P., Postma, D.S., Sausenthaler, S., Dagnelie, P.C., van den Brandt, P.A., Koletzko, B., Heinrich, J., Wichmann, H.-E., Schoetzau, A., Franke, K., Laubereau, B., Schaaf, B., Borte, M., Schulz, R., Sierig, G., Sack, U., Emmrich, F., von Berg, A., Bollrath, C., Herbarth, O., Diez, U., Lehmann, I., Herberth, G., (2010):
    Variants of the FADS1 FADS2 gene cluster, blood levels of polyunsaturated fatty acids and eczema in children within the first 2 years of life
    PLoS One 5 (10), e13261
    full text (url)
  • Schnabel, E., Heinrich, J., Wichmann, H.-E., Sausenthaler, S., Chen, C.M., Schnappinger, M., Borte, M., Diez, U., von Berg, A., Beckmann, C., Gross, I., Schaaf, B., Lehmann, I., Bauer, M., Röder, S., Herbarth, O., Link, E., Cramer, C., Bauer, C.P., Hoffmann, U., Behrendt, H., (2010):
    Respiratory tract infections and not paracetamol medication during infancy are associated with asthma development in childhood
    J. Allergy Clin. Immunol. 126 (5), 1071 - 1073
    full text (url)
  • Schnabel, E., Sausenthaler, S., Schaaf, B., Schäfer, T., Lehmann, I., Behrendt, H., Herbarth, O., Borte, M., Krämer, U., von Berg, A., Wichmann, H.-E., Heinrich, J., (2010):
    Prospective association between food sensitization and food allergy: results of the LISA birth cohort study
    Clin. Exp. Allergy 40 (3), 450 - 457
    full text (url)
  • Schütze, N., Lehmann, I., Bönisch, U., Simon, J.-C., Polte, T., (2010):
    Exposure to mycotoxins increases the allergic immune response in a murine asthma model
    Am. J. Respir. Crit. Care Med. 181 (11), 1188 - 1199
    full text (url)
to index

2009 (10)

  • Chen, C.M., Weidinger, S., Klopp, N., Sausenthaler, S., Bischof, W., Herbarth, O., Bauer, M., Borte, M., Schaaf, B., Lehmann, I., Behrendt, H., Krämer, U., Berdel, D., von Berg, A., Bauer, C.P., Koletzko, S., Illig, T., Wichmann, H.-E., Heinrich, J., LISA Study Group, , GINI Study Group, , (2009):
    Common variants in FCER1A influence total serum IgE levels from cord blood up to six years of life
    Allergy 64 (9), 1327 - 1332
    full text (url)
  • Cramer, C., Link, E., Sugiri, D., Wichmann, H., Heinrich, J., Sausenthaler, S., Lehmann, I., Herbarth, O., Borte, M., Behrendt, H., von Berg, A., Schaaf, B., Krämer, U., (2009):
    Day care attendance and eczema in East and West Germany - results from the LISA birth cohort study
    Allergy 64 (Suppl. 90), 100 - 100
    full text (url)
  • Herberth, G., Daegelmann, C., Röder, S., Behrendt, H., Kraemer, U., Borte, M., Heinrich, J., Herbarth, O., Lehmann, I., (2009):
    IL-17E but not IL-17A is associated with allergic sensitisation: results from the LISA study
    Allergy 64 (Suppl. 90), 50 - 50
    full text (url)
  • Herberth, G., Gubelt, R., Röder, S., Krämer, U., Schins, R., Diez, U., Borte, M., Heinrich, J., Wichmann, H.-E., Herbarth, O., Lehmann, I., (2009):
    Increase of inflammatory markers after indoor renovation activities: The LISA birth cohort study.
    Pediatr. Allergy Immunol. 20 (6), 563 - 570
    full text (url)
  • Herberth, G., Hinz, D., Röder, S., Diez, U., Borte, M., Lehmann, I., (2009):
    Innate versus adaptive immune response in pregnant women and corresponding cord bloods
    Cytom. Part A 75A (8), 717 - 718
    full text (url)
  • Lehmann, I., Lehmann, J., (2009):
    Flow-cytometric analysis of intracellularly stained cytokines, phosphoproteins, and microbial antigens
    In: Sack, U., Tarnok, A., Rothe, G., (eds.)
    Cellular diagnostics. Basic principles, methods and clinical applications of flow cytometry
    Karger, Basel, p. 459 - 475
  • Mörbt, N., Mögel, I., Kalkhof, S., Feltens, R., Röder-Stolinski, C., Zheng, J., Vogt, C., Lehmann, I., von Bergen, M., (2009):
    Proteome changes in human bronchoalveolar cells following styrene exposure indicate involvement of oxidative stress in the molecular-response mechanism
    Proteomics 9 (21), 4909 - 4933
    full text (url)
  • Oostingh, G.J., Wichmann, G., Schmittner, M., Lehmann, I., Duschl, A., (2009):
    The cytotoxic effects of the organophosphates chlorpyrifos and diazinon differ from their immunomodulating effects
    J. Immunotoxicol. 6 (2), 136 - 145
    full text (url)
  • Polte, T., Schütze, N., Lehmann, I., Simon, J., (2009):
    Mycotoxins exacerbate the allergic immune response in a murine asthma model
    Allergy 64 (Suppl. 90), 162
    full text (url)
  • Schnabel, E., Sausenthaler, S., Schaaf, B., Schaefer, T., Lehmann, I., Behrendt, H., Herbarth, O., Borte, M., Krämer, U., von Berg, A., Wichmann, H., Heinrich, J., (2009):
    Prospective association between food sensitisation and food allergy. Results of the LISA birth cohort study
    Allergy 64 (90), 163
    full text (url)
to index

2008 (11)

  • Brockow, I., Zutavern, A., Franke, K., Schaaf, B., von Berg, A., Krämer, U., Lehmann, I., Herbarth, O., Borte, M., Grübl, A., Bauer, C.P., Wichmann, H.E., Heinrich, J., (2008):
    Einfluss von Lebensbedingungen und Verhaltensweisen auf die Entwicklung von Immunsystem und Allergien im Ost-West-Vergleich (LISA). Design und bisherige Ergebnisse einer prospektiven Geburtskohortenstudie in Deutschland (Influences of lifestyle-related factors on the immune system and the development of allergies in childhood (LISA). Design and results to date of a prospective birth cohort study)
    Mon.schr. Kinderheilkd. 156 (3), 249 - 255
    full text (url)
  • Dägelmann, C., Herberth, G., Röder, S., Herbarth, O., Giese, T., Krämer, U., Behrendt, H., Borte, M., Heinrich, J., Emmrich, F., Lehmann, I., (2008):
    Association between suppressors of cytokine signalling, T-helper type 1/T-helper type 2 balance and allergic sensitization in children
    Clin. Exp. Allergy 38 (3), 438 - 448
    full text (url)
  • Fischäder, G., Röder-Stolinski, C., Wichmann, G., Nieber, K., Lehmann, I., (2008):
    Release of MCP-1 and IL-8 from lung epithelial cells exposed to volatile organic compounds
    Toxicol. Vitro 22 (2), 359 - 366
    full text (url)
  • Herberth, G., Gubelt, R., Röder, S., Krämer, U., Schins, R., Diez, U., Borte, M., Heinrich, J., Wichmann, H., Herbarth, O., Lehmann, I., (2008):
    Increase of inflammatory markers after indoor renovation activities: the LISA birth cohort study
    Allergy 63 (Suppl. 88), 471
    full text (url)
  • Herberth, G., Weber, A., Röder, S., Elvers, H.-D., Krämer, U., Schins, R.P.F., Diez, U., Borte, M., Heinrich, J., Schäfer, T., Herbarth, O., Lehmann, I., (2008):
    Relation between stressful life events, neuropeptides and cytokines: results from the LISA birth cohort study
    Pediatr. Allergy Immunol. 19 (8), 722 - 729
    full text (url)
  • Lehmann, I., Gubelt, R., Röder, S., Krämer, U., Schins, R., Borte, M., Diez, U., Heinrich, J., Behrendt, H., Herbarth, O., Herberth, G., (2008):
    Sex-dependent differences in the impact of environmental tobacco smoke to inflammatory response and allergic sensitisation in children - results from the LISAplus study
    Allergy 63 (Suppl. 88), 315
    full text (url)
  • Lehmann, I., Röder-Stolinski, C., Nieber, K., Fischäder, G., (2008):
    In vitro models for the assessment of inflammatory and immuno-modulatory effects of the volatile organic compound chlorobenzene
    Exp. Toxicol. Pathol. 60 (2-3), 185 - 193
    full text (url)
  • Luft, P., Oostingh, G., Gruijthuijsen, Y., Horejs-Hoeck, J., Lehmann, I., Duschl, A., (2008):
    Patulin influences the expression of Th1/Th2 cytokines by activated peripheral blood mononuclear cells and T cells through depletion of intracellular glutathione
    Environ.Toxicol. 23 (1), 84 - 95
    full text (url)
  • Röder-Stolinski, C., Feltens, R., Fischäder, G., Kohse, F., von Bergen, M., Mörbt, N., Oostingh, G., Eder, K., Duschl, A., Lehmann, I., (2008):
    Oxidative stress and NF-kB activation are induced by styrene in human lung epithelial cells
    Allergy 63 (Suppl. 88), 36 - 37
    full text (url)
  • Röder-Stolinski, C., Fischäder, G., Oostingh, G.J., Eder, K., Duschl, A., Lehmann, I., (2008):
    Chlorobenzene induces the NF-kB and p38 MAP kinase pathways in lung epithelial cells
    Inhal. Toxicol. 20 (9), 813 - 820
    full text (url)
  • Röder-Stolinski, C., Fischäder, G., Oostingh, G.J., Feltens, R., Kohse, F., von Bergen, M., Mörbt, N., Eder, K., Duschl, A., Lehmann, I., (2008):
    Styrene induces an inflammatory response in human lung epithelial cells via oxidative stress and NF-κB activation
    Toxicol. Appl. Pharmacol. 231 (2), 241 - 247
    full text (url)
to index

2007 (12)

  • Chen, C.M., Rzehak, P., Zutavern, A., Fahlbusch, B., Bischof, W., Herbarth, O., Borte, M., Lehmann, I., Behrendt, H., Krämer, U., Wichmann, H.-E., Heinrich, J., LISA Study Group, , (2007):
    Longitudinal study on cat allergen exposure and the development of allergy in young children
    J. Allergy Clin. Immunol. 119 (5), 1148 - 1155
    full text (url)
  • Chen, C., Rzehak, P., Zutavern, A., Fahlbusch, B., Bischof, W., Herbarth, O., Borte, M., Lehmann, I., Behrendt, H., Kraemer, U., Wichmann, H., Heinrich, J., (2007):
    Longitudinal study on cat allergen exposure and the development of allergy in young children
    Allergy 62 (Suppl. 83), 66 - 66
    full text (url)
  • Dägelmann, C., Herberth, G., Röder, S., Herbarth, O., Giese, T., Krämer, U., Behrendt, H., Borte, M., Lehmann, I., (2007):
    Association between SOCS1 and SOCS3 expression, T-cell regulation and development of allergic manifestations in children
    Allergy 62 (Suppl. 83), 461 - 462
    full text (url)
  • Fischäder, G., Röder-Stolinski, C., Wichmann, G., Lehmann, I., (2007):
    Chlorobenzene causes an inflammation in lung cells and a th2 polarisation in lymphocytes
    Allergy 62 (Suppl. 83), 474
    full text (url)
  • Hemdan, N.Y.A., Lehmann, I., Wichmann, G., Lehmann, J., Emmrich, F., Sack, U., (2007):
    Immunomodulation by mercuric chloride in vitro: application of different cell activation pathways
    Clin. Exp. Immunol. 148 (2), 325 - 337
    full text (url)
  • Herberth, G., Diez, U., Borte, M., Rehwagen, M., Röder, S., Herbarth, O., Lehmann, I., (2007):
    Priming of the fetal immune system by chemical exposure increases the risk for allergy development later in children's life
    Am. J. Reprod. Immunol. 58 (3), 196 - 197
  • Herberth, G., Weber, A., Lehmann, I., Röder, S., Herbarth, O., Krämer, U., Borte, M., Diez, U., Heinrich, J., (2007):
    Letter to the Editor. The stress of relocation and neuropeptides: an epidemiological study in children
    J. Psychosomat. Res. 63 (4), 451 - 452
    full text (url)
  • Herberth, G., Weber, A., Röder, S., Elvers, H., Krämer, U., Schins, R., Diez, U., Borte, M., Zutavern, A., Schäfer, T., Herbarth, O., Lehmann, I., (2007):
    Relation between stressful life events, expression of neuropeptides and immune regulation in children
    Allergy 62 (Suppl. 83), 404
    full text (url)
  • Lehmann, I., (2007):
    Intrazellulärer Zytokinnachweis
    In: Sack, U., Tarnok, A., Rothe, G., (eds.)
    Zelluläre Diagnostik : Grundlagen, Methoden und klinische Anwendungen der Durchflusszytometrie
    Karger, Basel, p. 647 - 660
  • Röder-Stolinski, C., Fischäder, G., Lehmann, I., (2007):
    Chlorobenzene induces MCP-1 in lung epithelial cells via the NF-kB pathway
    Allergy 62 (Suppl. 83), 474
    full text (url)
  • Sausenthaler, S., Koletzko, S., Schaaf, B., Lehmann, I., Borte, M., Herbarth, O., von Berg, A., Wichmann, H.-E., Heinrich, J., (2007):
    Maternal diet during pregnancy in relation to eczema and allergic sensitization in the offspring at 2 y of age
    Am. J. Clin. Nutr. 85 (2), 530 - 537
  • Tammer, B., Lehmann, I., Nieber, K., Altenburger, R., (2007):
    Combined effects of mycotoxin mixtures on human T cell function
    Toxicol. Lett. 170 (2), 124 - 133
    full text (url)
to index

2006 (4)

  • Hemdan, N.Y.A., Emmrich, F., Lehmann, I., Wichmann, G., Lehmann, J., Sack, U., (2006):
    Do alterations of Th1/Th2 reactivity by heavy metals cause induction of autoimmune diseases?
    Cell Prolif. 39 (5), 377
    full text (url)
  • Hemdan, N.Y.A., Emmrich, F., Sack, U., Wichmann, G., Lehmann, J., Adham, K., Lehmann, I., (2006):
    The in vitro immune modulation by cadmium depends on the way of cell activation
    Toxicology 222 (1-2), 37 - 45
    full text (url)
  • Herberth, G., Dägelmann, C., Weber, A., Röder, S., Giese, T., Krämer, U., Schins, R.P.F., Behrendt, H., Borte, M., Lehmann, I., (2006):
    Association between neuropeptides, Th1/Th2 polarization and allergy risk in children
    Cell Prolif. 39 (5), 365
    full text (url)
  • Herberth, G., Dägelmann, C., Weber, A., Röder, S., Giese, T., Krämer, U., Schins, R.P.F., Behrendt, H., Borte, M., Lehmann, I., (2006):
    Association of neuropeptides with Th1/Th2 balance and allergic sensitization in children
    Clin. Exp. Allergy 36 (11), 1408 - 1416
    full text (url)
to index

2005 (3)

  • Hemdan, N.Y., Emmrich, F., Adham, K., Wichmann, G., Lehmann, I., El-Massry, A., Ghoneim, H., Lehmann, J., Sack, U., (2005):
    Dose-dependent modulation of the in vitro cytokine production of human immune competent cells by lead salts
    Toxicol. Sci. 86 (1), 75 - 83
    full text (url)
  • Lehmann, I., Straub, S., Heinrich, J., Wichmann, H.-E., Herbarth, O., Röder, S., Diez, U., Borte, M., (2005):
    Einfluss von Umweltfaktoren auf die Entwicklung des frühkindlichen Immunsystems und Relevanz für das Allergierisiko
    Mon.schr. Kinderheilkd. 153 (Suppl. 2), K101.05F
  • Wichmann, G., Mühlenberg, J., Fischäder, G., Kulla, C., Rehwagen, M., Herbarth, O., Lehmann, I., (2005):
    An experimental model for the determination of immunomodulating effects by volatile compounds
    Toxicol. Vitro 19 (5), 685 - 693
    full text (url)
to index

2004 (10)

  • Fischäder, G., Wichmann, G., Mühlenberg, J., Kulla, C., Rehwagen, M., Nieber, K., Lehmann, I., (2004):
    An in vitro experimental model for the determination of immunomodulating effects by volatile compounds
    Immunobiology 209 (4-6), 468 - 469
    full text (url)
  • Funke, B., Maerz, H.K., Okorokow, S., Polata, S., Lehmann, I., Sack, U., Wild, P., Geisler, T., Zotz, R.J., (2004):
    Immunological evaluation of the new stable ultrasound contrast agent LK565: a phase one clinical trial
    Cardiovasc. Ultrasound 2 , art. 16
    full text (url)
  • Herbarth, O., Krumbiegel, P., Lehmann, I., Richter, T., Fritz, G.J., (2004):
    Which type of infection protects against allergies?
    Epidemiology 15 (4), S177 - S178
    full text (url)
  • Köller, G., Rolle-Kampczyk, U., Lehmann, I., Popp, P., Herbarth, O., (2004):
    Determination of Ochratoxin A in small volumes of human blood serum
    J. Chromatogr. B 804 (2), 313 - 317
    full text (url)
  • Krumbiegel, P., Lehmann, I., Alfreider, A., Fritz, G.J., Boeckler, D., Rolle-Kampczyk, U., Richter, M., Jorks, S., Müller, L., Richter, M.W., Herbarth, O., (2004):
    Helicobacter pylori determination in non-municipal drinking water and epidemiological findings
    Isot. Environ. Health Stud. 40 (1), 75 - 80
    full text (url)
  • Krumm, B., Altenburger, R., Nieber, K., Lehmann, I., (2004):
    Low concentration of mycotoxins with weak effects as single compounds mediate strong inhibition of IFN-gamma release when exposed together
    Immunobiology 209 (4-6), 470
    full text (url)
  • Negele, K., Heinrich, J., Borte, M., von Berg, A., Schaaf, B., Lehmann, I., Wichmann, H.-E., Bolte, G., (2004):
    Mode of delivery and development of atopic disease during the first 2 years of life
    Pediatr. Allergy Immunol. 15 (1), 48 - 54
    full text (url)
  • Rolle-Kampczyk, U.E., Fritz, G.J., Diez, U., Lehmann, I., Richter, M., Herbarth, O., (2004):
    Well water - one source of Helicobacter pylori colonization
    Int. J. Hyg. Environ. Health. 207 (4), 363 - 368
    full text (url)
  • Rolle-Kampczyk, U.E., Fritz, G.J., Diez, U., Lehmann, I., Richter, M., Herbarth, O., (2004):
    Contaminated well water: a risk factor for Heliobacter pylori infection
    In: Brebbia, C.A., (ed.)
    Risk analysis IV : papers from the 4th international conference on computer simulation in risk analysis and hazard mitigation : 27-29 September 2004, Rhodes, Greece
    Management Information Systems 9
    WIT Press, Southampton, p. 445 - 454
  • Wichmann, G., Dägelmann, C., Herbarth, O., Strauch, G., Schirmer, K., Wöstemeyer, J., Lehmann, I., (2004):
    Inflammatory activity in river-water samples
    Environ.Toxicol. 19 (6), 594 - 602
    full text (url)
to index

2003 (5)

  • Bolte, G., Bischof, W., Borte, M., Lehmann, I., Wichmann, H.-E., Heinrich, J., (2003):
    Early endotoxin exposure and atopy development in infants: results of a birth cohort study
    Clin. Exp. Allergy 33 (6), 770 - 776
    full text (url)
  • Diez, U., Rehwagen, M., Rolle-Kampczyk, U., Wetzig, H., Schulz, R., Richter, M., Lehmann, I., Borte, M., Herbarth, O., (2003):
    Redecoration of apartments promotes obstructive bronchitis in atopy risk infants - results of the LARS study
    Int. J. Hyg. Environ. Health. 206 (3), 173 - 179
    full text (url)
  • Lehmann, I., Müller, A., Diez, U., Richter, M., Wallach, S., Sierig, G., Seiffart, A., Wetzig, H., Borte, M., Herbarth, O., (2003):
    Indoor mould exposure reduces Th1 reactivity in early childhood
    Indoor Built Environ. 12 (4), 231 - 233
    full text (url)
  • Lehmann, I., Spiegl, U., Diez, U., Schulz, R., Borte, M., Herbarth, O., (2003):
    Visit of day nursery and common airway infections contribute to a higher TH1-reactivity in two-years-old children
    Epidemiology 14 (5), S40 - S41
    full text (url)
  • Wichmann, G., Krumm, B., Drößler, K., Herbarth, O., Lehmann, I., (2003):
    The effect of gliotoxin and patulin on human T cell function
    Indoor Built Environ. 12 (4), 255 - 258
    full text (url)
to index

2002 (16)

  • Diez, U., Rehwagen, M., Rolle-Kampczyk, U., Wetzig, H., Schulz, R., Richter, M., Lehmann, I., Borte, M., Herbarth, O., (2002):
    Redecoration of the dwelling and obstructive bronchitis in atopy-risk children
    Allergy 57 (Suppl. 73), 117 - 118
    full text (url)
  • Heinrich, J., Bolte, J., Hölscher, B., Douwes, J., Lehmann, I., Fahlbusch, B., Bischof, W., Weiss, M., Borte, M., Wichmann, H.-E., (2002):
    Allergen and endotoxin on mothers' mattresses and total IgE in cord blood of neonates
    Eur. Resp. J. 20 (3), 617 - 623
    full text (url)
  • Herbarth, O., Diez, U., Borte, M., Lehmann, I., Fritz, G., Kroessner, T., Metzner, G., Rehwagen, M., Richter, M., Schulz, R., Wetzig, H., (2002):
    Effect of indoor chemical exposure on the development of allergies in infancy
    Epidemiology 13 (4), S156 - S157
  • Herbarth, O., Diez, U., Lehmann, I., Müller, A., Rolle-Kampczyk, U., Wichmann, G., (2002):
    Umweltmedizinische Untersuchungen beim Vorliegen einer Schimmelpilzbelastung und Erfassung immunmodulatorischer Effekte
    In: Keller, R., Senkpiel, K., Samson, R.A., Hoekstra, E.S., (Hrsg.)
    Umgebungsanalyse bei gesundheitlichen Beschwerden durch mikrobielle Belastungen im Innenraum : 6. Lübecker Fachtagung für Umwelthygiene
    Schriftenreihe des Instituts für Medizinische Mikrobiologie und Hygiene der Universität zu Lübeck 6
    Schmidt-Römhild, Lübeck, S. 35 - 60
  • Krumm, B., Wichmann, G., Drößler, K., Lehmann, I., (2002):
    The effect of the mycotoxins gliotoxin and patulin on allergen specific T-cell regulation
    Immunobiology 206 (1-3), 213
    full text (url)
  • Lehmann, I., Borte, M., Diez, U., Rehwagen, M., Herbarth, O., (2002):
    Immunomodulating process and atopic diseases - Role of indoor-VOC
    Epidemiology 13 (4), S156
  • Lehmann, I., Diez, U., Rehwagen, M., Richter, M., Seiffart, A., Wetzig, H., Borte, M., Herbarth, O., (2002):
    Exposure to volatile organic compounds (VOC) during the third year of life increases the risk of atopic eczema at 4 - results of LARS
    Allergy 57 (Suppl. 73), 44 - 44
    full text (url)
  • Lehmann, I., Thoelke, A., Rehwagen, M., Rolle-Kampczyk, U., Schlink, U., Schulz, R., Borte, M., Diez, U., Herbarth, O., (2002):
    The influence of maternal exposure to volatile organic compounds on the cytokine secretion profile of neonatal T cells
    Environ.Toxicol. 17 (3), 203 - 210
    full text (url)
  • Lehmann, I., Thoelke, A., Weiss, M., Schlink, U., Schulz, R., Diez, U., Sierig, G., Emmrich, F., Jacob, B., Belcredi, P., Bolte, G., Heinrich, J., Herbarth, O., Wichmann, H.E., Borte, M., (2002):
    T cell reactivity in neonates from an East and a West German city - results of the LISA study
    Allergy 57 (2), 129 - 136
    full text (url)
  • Lehmann, I., Thoelke, A., Weiss, M., Schultz, R., Diez, U., Wichmann, H.-E., Herbarth, O., Borte, M., (2002):
    Reduced TH1 reactivity in cord blood is associated with the development of respiratory diseases and allergic sensitization during infancy
    Epidemiology 13 (4), S156
  • Lohmann, T., Laue, S., Nietzschmann, U., Kapellen, T.M., Lehmann, I., Schroeder, S., Paschke, R., Kiess, W., (2002):
    Reduced expression of Th1-associated chemokine receptors on peripheral blood lymphocytes at diagnosis of type 1 diabetes
    Diabetes 51 (8), 2474 - 2480
    full text (url)
  • Müller, A., Lehmann, I., Seiffart, A., Diez, U., Wetzig, H., Borte, M., Herbarth, O., (2002):
    Increased incidence of allergic sensitisation and respiratory diseases due to mould exposure: Results of the Leipzig Allergy Risk children Study (LARS)
    Int. J. Hyg. Environ. Health. 204 (5-6), 363 - 365
    full text (url)
  • Oertel, M., Sack, U., Kohlhaw, K., Lehmann, I., Emmrich, F., Berr, F., Hauss, J., Schwarz, R., (2002):
    Induction therapy including antithymocyte globulin induces marked alterations in T lymphocyte subpopulations after liver transplantation: results of a long-term study
    Transpl. Int. 15 (9-10), 463 - 471
    full text (url)
  • Reichardt, P., Lehmann, I., Sierig, G., Borte, M., (2002):
    Analysis of T-sell receptor V-beta 2 in peripheral blood lymphocytes as a diagnostic marker for Kawasaki disease
    Infection 30 (6), 360 - 364
    full text (url)
  • Wichmann, G., Herbarth, O., Lehmann, I., (2002):
    The mycotoxins citrinin, gliotoxin, and patulin affect interferon-γ rather than interleukin-4 production in human blood cells
    Environ.Toxicol. 17 (3), 211 - 218
    full text (url)
  • Wichmann, G., Lehmann, I., (2002):
    In vitro Models for the detection of immunomodulating properties of pharmaceuticals
    In: Wohlrab, J., Neubert, R.R.H., Marsch, W.C., (eds.)
    Trends in dermatopharmacy
    Trends in Clinical and Experimental Dermatology 1
    Shaker, Aachen, p. 236 - 246
to index

2001 (19)

  • Diez, U., Borte, M., Fritzsch, C., Herbarth, O., Lehmann, I., Metzner, G., Müller, A., Rehwagen, M., Richter, M., Rolle-Kampczyk, U., Schuster, V., Schwenke, A., Thomas, A., (2001):
    Kooperation in der Umweltmedizin in Leipzig - Vorstellung des LEIPI-Programms zur Untersuchung von Patienten mit Schimmelpilzbelastung. Cooperation in environmental medicine - the "LEIPI" program
    Umweltmed. Forsch. Prax. 6 (2), 97 - 100
    full text (url)
  • Diez, U., Borte, M., Rehwagen, M., Kroessner, T., Wetzig, H., Schulz, R., Lehmann, I., Schlink, U., Herbarth, O., (2001):
    Effect of indoor chemical exposure on respiratory infections and atopic sensitisation in young atopy risk children
    Allergy 56 (Suppl. 68), 246
    full text (url)
  • Diez, U., Feyer, A., Wetzig, H., Rehwagen, M., Rolle-Kampczyk, U., Lehmann, I., Schlink, U., Borte, M., Herbarth, O., (2001):
    The effect of redecoration on obstructive bronchitis in 4-year-old atopy risk children - results of the Leipzig allergy risk children study (LARS)
    Int. J. Hyg. Environ. Health. 204 (4), 280
    full text (url)
  • Herbarth, O., Diez, U., Fritz, G.J., Kroessner, T., Krumbiegel, P., Lehmann, I., Metzner, G., Müller, A., Rehwagen, M., Richter, M., Rolle-Kampczyk, U., Schlink, U., Schulz, R., Wetzig, H., Borte, M., (2001):
    Allergieentwicklung im frühen Kindesalter
    In: Ring, J., Darsow, U., (Hrsg.)
    Allergie 2000: Probleme, Strategien und praktische Konsequenzen
    Fortschritte der Allergologie und Immunologie 21
    Dustri-Verlag Dr. Karl Feistle, München, S. 30 - 39
  • Kohlhaw, K., Sack, U., Lehmann, I., Drews, G., Hartwig, T., Tannapfel, A., Berr, F., Oertel, M., Marx, U., Lehmann, M., Hauss, J., Emmrich, F., (2001):
    The monoclonal anti-CD4 antibody RIB5/2 induces donor-specific tolerance in the high-responder liver transplant model in the rat
    Transplant. Proc. 33 (3), 2371 - 2373
    full text (url)
  • Kohlhaw, K., Sack, U., Lehmann, I., Drews, G., Schwarz, R., Hartwig, T., Tannapfel, A., Berr, F., Oertel, M., Marx, U., Lehmann, M., Witterkind, C., Hauss, J., Emmrich, F., (2001):
    Anti-CD4-induced long-term acceptance of rat liver allografts in a high-responder model is not based on pure immunosuppression
    Transplant. Proc. 33 (3), 2173 - 2175
    full text (url)
  • Krumbiegel, P., Lehmann, I., Herbarth, O., Alfreider, A., (2001):
    H. pylori in non-municipal drinking water: epidemiological and microbiological evidence
    11th International Workshop on Campylobacter, Helicobacter & Related Organisms, Freiburg, 1.-5.9.2001
  • Krumbiegel, P., Lehmann, I., Herbarth, O., Alfreider, A., Fritz, G.J., Boeckler, D., Richter, M., Richter, T., (2001):
    Helicobacter pylori in German non-municipal drinking water: epidemiology and microbiology in evidence
    Int. J. Med. Microbiol. 291 (Suppl. 31), 1
  • Laue, S., Nietzschmann, U., Kapellen, T.M., Lehmann, I., Paschke, R., Kiess, W., Lohmann, T., (2001):
    Reduced expression of TH1 associated chemokine receptors on peripheral blood lymphocytes of patients with newly diagnosed type 1 diabetes
    Diabetologia 44 (S1), A74
    full text (url)
  • Lehmann, I., Borte, M., Sack, U., (2001):
    Diagnostik von Immundefekten. Diagnosis of Immunodeficiencies
    LaboratoriumsMedizin 25 , 495 - 511
    full text (url)
  • Lehmann, I., Rehwagen, M., Diez, U., Seiffart, A., Rolle-Kampczyk, U., Richter, M., Wetzig, H., Borte, M., Herbarth, O., (2001):
    Enhanced in vivo IgE production and T cell polarization toward the type 2 phenotype in association with indoor exposure to VOC: results of the LARS study
    Int. J. Hyg. Environ. Health. 204 (4), 211 - 221
    full text (url)
  • Lehmann, I., Rehwagen, M., Diez, U., Seiffart, A., Rolle-Kampczyk, U., Richter, M., Wetzig, H., Borte, M., Herbarth, O., (2001):
    Indoor exposure to volatile organic compounds (VOC) is associated with T cell polarization toward the type 2 phenotype and allergic sensitization to food allergens: results of the LARS study
    Immunobiology 204 (1-2), 281 - 282
    full text (url)
  • Lehmann, I., Thoelke, A., Rehwagen, M., Schlink, U., Schulz, R., Borte, M., Diez, U., Herbarth, O., (2001):
    The cytokine secretion profile of neonatal T cells is influenced by maternal exposure to volatile organic compounds (VOC)
    10th International Symposium on Toxicity Assessment, ISTA, Quebec, Canada, August 26-31, 2001
    p. 12
  • Lehmann, I., Thoelke, A., Rehwagen, M., Schlink, U., Weiss, M., Schulz, R., Borte, M., (2001):
    Influence of maternal exposure to volatile organic compounds (VOC) on T cell reactivity in neonates
    Int. J. Hyg. Environ. Health. 204 (4), 281
    full text (url)
  • Lehmann, I., Wichmann, G., Wallach, S., Sierig, G., Müller, A., Schulz, R., Borte, M., Diez, U., Herbarth, O., (2001):
    TH1 suppression in early childhood following indoor mould exposure - the role of mycotoxins
    Allergy 56 (Suppl. 68), 43 - 44
    full text (url)
  • Müller, A., Lehmann, I., Seiffart, A., Wetzig, H., Diez, U., Borte, M., Herbarth, O., (2001):
    Association of indoor airborne mould spores with respiratory diseases and allergic sensitization
    Allergo J. 10 , 81 - 82
  • Müller, A., Lehmann, I., Wetzig, H., Diez, U., Borte, M., Herbarth, O., (2001):
    Asthma related symptoms and atopic sensibilisation of children by house dust mite exposure
    Allergy 56 (Suppl. 68), 244
    full text (url)
  • Wichmann, G., Herbarth, O., Müller, A., Rolle-Kampczyk, U., Lehmann, I., (2001):
    The mycotoxins citrinin, gliotoxin and patulin affect TH1 rather than TH2 cytokine production in vitro
    10th International Symposium on Toxicity Assessment, ISTA, Quebec, Canada, August 26-31, 2001
  • Wichmann, G., Lehmann, I., (2001):
    The mycotoxins gliotoxin, patulin, and penicillic acid favor Th2 cytokine production
    Immunobiology 204 (1-2), 287
    full text (url)
to index

2000 (17)

  • Borte, M., Diez, U., Herbarth, O., Meusel, S., Müller, A., Müller, D., Rehwagen, M., Lehmann, I., Rolle-Kampczyk, U., Schilde, M., Sierig, G., Springer, A., Wetzig, H., (Hrsg., 2000):
    LARS - Leipziger Allergierisiko-Kinder-Studie. Abschlussbericht für das SMWK zum Projekt 4-7531.50-03-UFZ/701
    Sächsisches Staatsministerium für Wissenschaft und Kunst, Dresden, 222 S.
  • Borte, M., Lehmann, I., Reichardt, P., Sierig, G., Handrick, W., Kiess, W., (2000):
    Die Bedeutung von TCR Vβ2+T-Zellen für die Früherkennung des Kawasaki-Syndroms (KS)
    Sozialpädiatrie 22 (7/8), 338
  • Herbarth, O., Diez, U., Fritz, G.J., Kroessner, T., Krumbiegel, P., Lehmann, I., Metzner, G., Müller, A., Rehwagen, M., Richter, M., Schulz, R., Wetzig, H., Borte, M., (2000):
    Air pollution-dependent changes in the morbidity of children
    In: Longhurst, J.W.S., Brebbia, C.A., Power, H., (eds.)
    Air pollution VIII
    WIT Transactions on Ecology and the Environment 42
    WIT Press, Southampton, p. 775 - 781
    full text (url)
  • Herbarth, O., Diez, U., Fritz, G.J., Rehwagen, M., Kroessner, T., Borte, M., Wetzig, H., Lehmann, I., Müller, A., Metzner, G., Richter, M., Schulz, R., (2000):
    Effect of indoor chemical exposure on the development of allergies in newborns - LARS study
    Proceedings of Healthy Buildings 2000 held in Espoo, Finland, 6-10 August 2000
    Vol. 1
    p. 281 - 286
  • Krumbiegel, P., Boeckler, D., Lehmann, I., Jorks, S., Fritz, G.J., Babel, W., Richter, T., Herbarth, O., (2000):
    Is water a source of H. pylori infection in Central Europe?
    Gut 47 (Suppl. 1), A46
  • Lehmann, I., Brylla, E., Sittig, D., Spanel-Borowski, K., Aust, G., (2000):
    Microvascular endothelial cells differ in their basal and tumour necrosis factor-α-regulated expression of adhesion molecules and cytokines
    J. Vasc. Res. 37 (5), 408 - 416
    full text (url)
  • Lehmann, I., Rehwagen, M., Diez, U., Richter, M., Seiffart, A., Wetzig, H., Borte, M., Herbarth, O., (2000):
    VOC-Belastung im Innenraum ist assoziiert mit einer TH2-lastigen T-Zell-Immunität und allergischen Sensibilisierungen
    VI. Thüringer Umwelthygienesymposium, Jena, 24.11.2000
  • Lehmann, I., Rehwagen, M., Diez, U., Seiffart, A., Rolle-Kampczyk, U., Richter, M., Wetzig, H., Borte, M., Herbarth, O., (2000):
    Enhanced in vivo IgE production and TH2 reactivity resulting from indoor exposure to VOC: results of the LARS study
    4th Annual Meeting of the International Society of Environmental Medicine (ISEM), Hannover, 1.-4.10.2000
  • Lehmann, I., Rehwagen, M., Diez, U., Seiffart, A., Rolle-Kampczyk, U., Richter, M., Wetzig, H., Borte, M., Herbarth, O., (2000):
    Indoor exposure (VOC) dependent in vivo IgE production and TH2 reactivity in young children - LARS study
    International Symposium New Trends in Allergy V, Davos, 15.-17.9.2000
  • Lehmann, I., Thoelke, A., Weiss, M., Schulz, R., Sierig, G., Sack, U., Jacob, B., Schoetzau, A., Bolte, G., Herbarth, O., Wichmann, H.-E., Borte, M., (2000):
    T cell reactivity in neonates from an East and a West German city - results of the LISA study
    Immunobiology 203 (1-3), 272
    full text (url)
  • Lehmann, J., Enssle, K.H., Lehmann, I., Emmendorfer, A., Lohmann-Matthes, M.L., (2000):
    The capacity to produce IFN-gamma rather than the presence of interleukin-4 determines the resistance and the degree of susceptibility to Leishmania donovani infection in mice
    J. Interferon Cytokine Res. 20 (1), 63 - 77
    full text (url)
  • Lehmann, J., Jüngel, A., Lehmann, I., Busse, F., Biskop, M., Saalbach, A., Emmrich, F., Sack, U., (2000):
    Grafting of fibroblasts isolated from the synovial membrane of rheumatoid arthritis (RA) patients induces chronic arthritis in SCID mice - A novel model for studying the arthritogenic role of RA fibroblasts in vivo
    J. Autoimmun. 15 (3), 301 - 313
    full text (url)
  • Müller, A., Lehmann, I., Seiffart, A., Wetzig, H., Diez, U., Borte, M., Herbarth, O., (2000):
    Anstieg von allergischen Sensibilisierungen und Atemwegserkrankungen durch Schimmelpilzexposition
    VI. Thüringer Umwelthygienesymposium, Jena, 24.11.2000
  • Oertel, M., Kohlhaw, K., Lehmann, I., Schwarz, R., Emmrich, F., Hauss, J., Sack, U., (2000):
    Alterations in T lymphocyte subpopulations after liver transplantation
    Immunobiology 203 (1-3), 245
    full text (url)
  • Sierig, G., Lehmann, I., Borte, M., Kiess, W., (2000):
    Entwicklung der humuralen Immunität ehemals untergewichtiger Neugeborener innerhalb der ersten Lebensjahre
    Sozialpädiatrie 22 (9/10), 268
  • Simchen, C., Lehmann, I., Sittig, D., Steinert, M., Aust, G., (2000):
    Expression and regulation of regulated on activation, normal T cells expressed and secreted in thyroid tissue of patients with Graves' disease and thyroid autonomy and in thyroid-derived cell populations
    J. Clin. Endocrinol. Metab. 85 (12), 4758 - 4764
    full text (url)
  • Wichmann, G., Müller, A., Rolle-Kampczyk, U., Herbarth, O., Lehmann, I., (2000):
    Mycotoxins affect Th1 rather than Th2 cytokine production in vitro
    Immunobiology 203 (1-3), 580
    full text (url)
to index