Dr. Elisabet Teixido Condomines
Elisabet Teixidó studied Pharmacy at the University of Barcelona. She received the master thesis diploma for her work on the “Evaluation of the zebrafish embryo as an early detection system of aquatic contamination by chemical substances” within the frame of the project: “Technological advances towards the Self-sustainable Urban Water Cycle (SOSTAQUA)”, carried out at the Toxicology Unit of the University of Barcelona and forming a business consortium led by AGBAR (the Barcelona Water Authority).
During her PhD studies at the Toxicology Unit, Health department of the University of Barcelona, she improved the characterization of endpoints related to developmental retardation in the zebrafish embryo test and defined a new scoring system for the teratogenicity assay. Her work also included the developmental toxicity evaluation of several environmental pollutants, e.g. water disinfection by-products and polychlorinated biphenyls in the zebrafish model.
In parallel with her PhD elaboration, she participated in an international network (CORNUCOPIA) that aimed to characterize and evaluate the safety of different bioactive compounds as food ingredients. In this project, the zebrafish embryo test has been introduced as a useful alternative model to test the safety and efficacy of several bioactive compounds. In 2014 she did a postdoc at the Universitat Autònoma de Barcelona at the department of Genetics and Microbiology (Mutagenesis group).
In June 2015 joined the Department of Bioanalytical Ecotoxicology at the UFZ Leipzig and she is involved in the BMBF project “Entwicklung einer Strategie zur Reduzierung von Tierversuchen für die Teratogenitätsprüfung durch Kombination von Säugerversuchen mit dem Zebrabärblingsembryotest (ZFminus1)”. The project aims the application of zebrafish embryo tests and in silico approaches to achieve the same level of predictivity in developmental safety testing when tests are conducted in two mammalian test species (rat and rabbit). A particular focus of the work is on the improvement of the zebrafish embryo test endpoints by developing a toolset for automated quantification of morphological features.