Prof. Dr. Rolf Altenburger

Address:
Permoserstr. 15
04318 Leipzig
Germany

Building: 6.0
Room: 317
Phone: +49 341 235 1285

Dr. Rolf Altenburger

Curriculum Vitae

Rolf Altenburger is Head of the Department Bioanalytical Ecotoxicology since 2005. He holds a professorship at the RWTH Aachen University, Institute for Environmental Research. His professional activities comprise the Editorial Board of Environmental Pollution, Membership in advisory groups, e.g. on the German plant protection action plan or being speaker of the HGF programme topic Chemicals in the Environment (CITE).

Rolf Altenburger received his Doctor of Science from the University of Bremen. Previous to his appointment at the RWTH Aachen he held a venia legendi at the University of Bremen and the TU Bergakademie Freiberg. His professional training as a biologist included studies at the Universities of Marburg, Freiburg, and Bremen, Germany, and St.Andrews, Scotland. He obtained research fellowships to Shabat Alam Malaysia, Penang, Malaysa; Visaya State College of Agriculture, Leyte, The Philippines; Roswell Park Cancer Institute, Buffalo, NY, USA; and the National Research Centre for Environmental Toxicology (ENTOX), Brisbane, Australia.

Rolf Altenburger’s research interests focus on

Mixture toxicity assessment for complex environmental exposure;

Bioassays for toxicant identification at multiple contaminated sites;

Mode-of-action analysis for toxicants;

Pharmacokinetic-pharmacodynamic (PKPD) models to mechanistically describe concentration and time dependent toxicity.

Traditional chemicals risk assessment considers chemicals one by one while organisms in the environment typically are confronted with exposure to multiple substances. For more than a decade, we have been investigating mixture effects to improve environmental risk assessment. Milestones in our work comprise answers to the following questions: Can we establish bioassays that allow detection of combination effects? For several ecotoxicity assays from subcellular to community level we could successfully demonstrate this. Secondly, can we predict mixture toxicity based on the information about the components biological activities? For apical effects and an array of mixtures of environmental contaminants we could support the notion that extrapolative modelling is indeed possible. The more precise the prediction is needed, the more mechanism-based information is required. Currently, want to extend our knowledge in two directions: namely the understanding of mixture interactions at a molecular level (Exposome) and the combined effects under conditions of multiple stress.

Publications

2011 - today

2019 (9)

Altenburger, R., Brack, W., Burgess, R.M., Busch, W., Escher, B.I., Focks, A., Hewitt, L.M., Jacobsen, B.N., López de Alda, M., Ait-Aissa, S., Backhaus, T., Ginebreda, A., Hilscherová, K., Hollender, J., Hollert, H., Neale, P.A., Schulze, T., Schymanski, E.L., Teodorovic, I., Tindall, A.J., De Aragão Umbuzeiro, G., Vrana, B., Zonja, B., Krauss, M., (2019):
Future water quality monitoring: improving the balance between exposure and toxicity assessments of real-world pollutant mixtures
Environ. Sci. Eur. 31 , art. 12
full text (url)
Brack, W., Ait-Aissa, S., Altenburger, R., Cousins, I., Dulio, V., Escher, B., Focks, A., Ginebreda, A., Hering, D., Hilscherová, K., Hollender, J., Hollert, H., Kortenkamp, A., López de Alda, M., Posthuma, L., Schymanski, E., Segner, H., Slobodnik, J., (2019):
Let us empower the WFD to prevent risks of chemical pollution in European rivers and lakes
Environ. Sci. Eur. 47 , art. 47
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Brack, W., Ait-Aissa, S., Backhaus, T., Dulio, V., Escher, B.I., Faust, M., Hilscherova, K., Hollender, J., Hollert, H., Müller, C., Munthe, J., Posthuma, L., Seiler, T.-B., Slobodnik, J., Teodorovic, I., Tindall, A.J., De Aragão Umbuzeiro, G., Zhang, X., Altenburger, R., (2019):
Effect‑based methods are key. The European Collaborative Project SOLUTIONS recommends integrating effect‑based methods for diagnosis and monitoring of water quality
Environ. Sci. Eur. 31 , art. 10
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Brack, W., Altenburger, R., (2019):
Projekt Solutions: Mikroschadstoffe in europäischen Gewässern
Wasserwirtschaft, Wassertechnik : wwt (4), 15 - 20
Leuthold, D., Klüver, N., Altenburger, R., Busch, W., (2019):
Can environmentally relevant neuroactive chemicals specifically be detected with the locomotor response test in zebrafish embryos?
Environ. Sci. Technol. 53 (1), 482 - 493
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Schäfer, R.B., Liess, M., Altenburger, R., Filser, J., Hollert, H., Roß-Nickoll, M., Schäffer, A., Scheringer, M., (2019):
Future pesticide risk assessment: narrowing the gap between intention and reality
Environ. Sci. Eur. 31 , art. 21
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Schmidt, S., Altenburger, R., Kühnel, D., (2019):
From the air to the water phase: implication for toxicity testing of combustion-derived particles
Biomass Convers. Biorefinery 9 (1), 213 - 225
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Schüttler, A., Altenburger, R., Ammar, M., Bader-Blukott, M., Jakobs, G., Knapp, J., Krüger, J., Reiche, K., Wu, G.-M., Busch, W., (2019):
Map and model—moving from observation to prediction in toxicogenomics
GigaScience 8 (6), giz057
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Serra, H., Scholze, M., Altenburger, R., Busch, W., Budzinski, H., Brion, F., Aït-Aïssa, S., (2019):
Combined effects of environmental xeno-estrogens within multi-component mixtures: Comparison of in vitro human- and zebrafish-based estrogenicity bioassays
Chemosphere 227 , 334 - 344
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2018 (5)

Altenburger, R., Scholze, M., Busch, W., Escher, B.I., Jakobs, G., Krauss, M., Krüger, J., Neale, P.A., Ait-Aissa, S., Almeida, A.C., Seiler, T.-B., Brion, F., Hilscherová, K., Hollert, H., Novák, J., Schlichting, R., Serra, H., Shao, Y., Tindall, A., Tolefsen, K.-E., Umbuzeiro, G., Williams, T.D., Kortenkamp, A., (2018):
Mixture effects in samples of multiple contaminants – An inter-laboratory study with manifold bioassays
Environ. Int. 114 , 95 - 106
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Diamond, J., Altenburger, R., Coors, A., Dyer, S.D., Focazio, M., Kidd, K., Koelmans, A.A., Leung, K.M.Y., Servos, M.R., Snape, J., Tolls, J., Zhang, X., (2018):
Use of prospective and retrospective risk assessment methods that simplify chemical mixtures associated with treated domestic wastewater discharges
Environ. Toxicol. Chem. 37 (3), 690 - 702
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Naasz, S., Altenburger, R., Kühnel, D., (2018):
Environmental mixtures of nanomaterials and chemicals: The Trojan-horse phenomenon and its relevance for ecotoxicity
Sci. Total Environ. 635 , 1170 - 1181
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Scholz, S., Schreiber, R., Armitage, J., Mayer, P., Escher, B.I., Lidzba, A., Léonard, M., Altenburger, R., (2018):
Meta‐analysis of fish early life stage tests—Association of toxic ratios and acute‐to‐chronic ratios with modes of action
Environ. Toxicol. Chem. 37 (4), 955 - 969
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Whalley, C., Mohaupt, V., Busch, W., van den Roovaart, J., van Dujnhoven, N., Kirst, I., Schmedtje, U., Altenburger, R., Sommer, L., (2018):
Chemicals in European waters : knowledge developments
EEA Report 18/2018
Office for Official Publications of the European Communities, Luxembourg, 76 pp.
full text (url)

2017 (11)

Altenburger, R., Gündel, U., Rotter, S., Vogs, C., Faust, M., Backhaus, T., (2017):
Establishment of a concept for comparative risk assessment of plant protection products with special focus on the risks to the environment. Project No. (FKZ) 3712 67 406. Report No. (UBA-FB) 002256/ENG
Texte Umweltbundesamt 47/2017
Umweltbundesamt, Dessau-Roßlau, 215 pp.
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Brack, W., Dulio, V., Ågerstrand, M., Allan, I., Altenburger, R., Brinkmann, M., Bunke, D., Burgess, R.M., Cousins, I., Escher, B.I., Hernández, F.J., Hewitt, L.M., Hilscherová, K., Hollender, J., Hollert, H., Kase, R., Klauer, B., Lindim, C., López Herráez, D., Miège, C., Munthe, J., O'Toole, S., Posthuma, L., Rüdel, H., Schäfer, R.B., Sengl, M., Smedes, F., van de Meent, D., van den Brink, P., van Gils, J., van Wezel, A.P., Dick Vethaak, A., Vermeirssen, E., von der Ohe, P.C., Vrana, B., (2017):
Towards the review of the European Union Water Framework Directive: Recommendations for more efficient assessment and management of chemical contamination in European surface water resources
Sci. Total Environ. 576 , 720 - 737
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Crawford, S.E., Brüll, C., Aumeier, B., Brinkmann, M., Classen, E., Esser, V., Ganal, C., Kaip, E., Häussling, R., Lehmkuhl, F., Letmathe, P., Müller, A.-K., Rabinovitch, I., Reicherter, K., Schwarzbauer, J., Schmitt, M., Stauch, G., Wessling, M., Yüce, S., Hecker, M., Kidd, K.A., Altenburger, R., Brack, W., Schüttrumpf, H., Hollert, H., (2017):
Project house water: a novel interdisciplinary framework to assess the environmental and socioeconomic consequences of flood-related impacts
Environ. Sci. Eur. 29 , art. 23
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Escher, B.I., Hackermüller, J., Polte, T., Scholz, S., Aigner, A., Altenburger, R., Böhme, A., Bopp, S.K., Brack, W., Busch, W., Chadeau-Hyam, M., Covaci, A., Eisenträger, A., Galligan, J.J., Garcia-Reyero, N., Hartung, T., Hein, M., Herberth, G., Jahnke, A., Kleinjans, J., Klüver, N., Krauss, M., Lamoree, M., Lehmann, I., Luckenbach, T., Miller, G.W., Müller, A., Phillips, D.H., Reemtsma, T., Rolle-Kampczyk, U., Schüürmann, G., Schwikowski, B., Tan, Y.-M., Trump, S., Walter-Rohde, S., Wambaugh, J.F., (2017):
From the exposome to mechanistic understanding of chemical-induced adverse effects
Environ. Int. 99 , 97 - 106
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Jakob, L., Bedulina, D.S., Axenov-Gribanov, D.V., Ginzburg, M., Shatilina, Z.M., Lubyaga, Y.A., Madyarova, E.V., Gurkov, A.N., Timofeyev, M.A., Portner, H.-O., Sartoris, F.J., Altenburger, R., Luckenbach, T., (2017):
Uptake kinetics and subcellular compartmentalization explain lethal but not sublethal effects of cadmium in two closely related amphipod species
Environ. Sci. Technol. 51 (12), 7208 - 7218
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Kühnert, A., Vogs, C., Seiwert, B., Aulhorn, S., Altenburger, R., Hollert, H., Küster, E., Busch, W., (2017):
Biotransformation in the zebrafish embryo – temporal gene transcription changes of cytochrome P450 enzymes and internal exposure dynamics of the AhR binding xenobiotic benz[a]anthracene
Environ. Pollut. 230 , 1 - 11
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Munthe, J., Brorström-Lundén, E., Rahmberg, M., Posthuma, L., Altenburger, R., Brack, W., Bunke, D., Engelen, G., Gawlik, B.M., van Gils, J., López Herráez, D., Rydberg, T., Slobodnik, J., van Wezel, A., (2017):
An expanded conceptual framework for solution-focused management of chemical pollution in European waters
Environ. Sci. Eur. 29 , art. 13
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Neale, P.A., Altenburger, R., Aït-Aïssa, S., Brion, F., Busch, W., De Aragão Umbuzeiro, G., Denison, M.S., Du Pasquier, D., Hilscherová, K., Hollert, H., Morales, D.A., Novák, J., Schlichting, R., Seiler, T.-B., Serra, H., Shao, Y., Tindall, A.J., Tollefsen, K.E., Williams, T.D., Escher, B.I., (2017):
Development of a bioanalytical test battery for water quality monitoring: Fingerprinting identified micropollutants and their contribution to effects in surface water
Water Res. 123 , 734 - 750
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Neale, P.A., Munz, N.A., Aїt-Aїssa, S., Altenburger, R., Brion, F., Busch, W., Escher, B.I., Hilscherová, K., Kienle, C., Novák, J., Seiler, T.-B., Shao, Y., Stamm, C., Hollender, J., (2017):
Integrating chemical analysis and bioanalysis to evaluate the contribution of wastewater effluent on the micropollutant burden in small streams
Sci. Total Environ. 576 , 785 - 795
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Schmidt, S., Busch, W., Altenburger, R., (2017):
Biotestverfahren zur Abschätzung von Wirkpotenzialen in der aquatischen Umwelt : Vorschlag einer modularen Biotestbatterie für das aquatische Umweltmonitoring als Ergebnis einer systematischen Literaturrecherche und Bewertung
LUBW Landesanstalt für Umwelt Baden-Württemberg, Karlsruhe, 98 S.
Schüttler, A., Reiche, K., Altenburger, R., Busch, W., (2017):
The transcriptome of the zebrafish embryo after chemical exposure: a meta-analysis
Toxicol. Sci. 157 (2), 291 - 304
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2016 (7)

Busch, W., Schmidt, S., Kühne, R., Schulze, T., Krauss, M., Altenburger, R., (2016):
Micropollutants in European rivers: A mode of action survey to support the development of effect-based tools for water monitoring
Environ. Toxicol. Chem. 35 (8), 1887 - 1899
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Faria, M., Pavlichenko, V.V., Burkhardt-Medicke, K., Soares, A.M.V.M., Altenburger, R., Barata, C., Luckenbach, T., (2016):
Use of a combined effect model approach for discriminating between ABCB1- and ABCC1-type efflux activities in native bivalve gill tissue
Toxicol. Appl. Pharmacol. 297 , 56 - 67
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Faria, M., Pavlichenko, V.V., Burkhardt-Medicke, K., Soares, A.M.V.M., Altenburger, R., Barata, C., Luckenbach, T., (2016):
Corrigendum to "Use of a combined effect model approach for discriminating between ABCB1- and ABCC1-type efflux activities in native bivalve gill tissue" [Toxicol. Appl. Pharmacol. (2016) 56–67]
Toxicol. Appl. Pharmacol. 303 , 110
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Klüver, N., Vogs, C., Altenburger, R., Escher, B.I., Scholz, S., (2016):
Development of a general baseline toxicity QSAR model for the fish embryo acute toxicity test
Chemosphere 164 , 164 - 173
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Rose, S., Altenburger, R., Sturm, A., (2016):
Mixture toxicity effects of sea louse control agents in Daphnia magna
Chemosphere 144 , 599 - 606
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Schmidt, S., Busch, W., Altenburger, R., Küster, E., (2016):
Mixture toxicity of water contaminants-effect analysis using the zebrafish embryo assay (Danio rerio)
Chemosphere 152 , 503 - 512
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Vogs, C., Altenburger, R., (2016):
Time-dependent effects in algae for chemicals with different adverse outcome pathways: a novel approach
Environ. Sci. Technol. 50 (14), 7770 - 7780
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2015 (9)

Altenburger, R., Ait-Aissa, S., Antczak, P., Backhaus, T., Barceló, D., Seiler, T.-B., Brion, F., Busch, W., Chipman, K., López de Alda, M., De Aragão Umbuzeiro, G., Escher, B.I., Falciani, F., Faust, M., Focks, A., Hilscherova, K., Hollender, J., Hollert, H., Jäger, F., Jahnke, A., Kortenkamp, A., Krauss, M., Lemkine, G.F., Munthe, J., Neumann, S., Schymanski, E.L., Scrimshaw, M., Segner, H., Slobodnik, J., Smedes, F., Kughathas, S., Teodorovic, I., Tindall, A.J., Tollefsen, K.E., Walz, K.-H., Williams, T.D., van den Brink, P.J., van Gils, J., Vrana, B., Zhang, X., Brack, W., (2015):
Future water quality monitoring — Adapting tools to deal with mixtures of pollutants in water resource management
Sci. Total Environ. 512-513 , 540 - 551
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Brack, W., Altenburger, R., Schüürmann, G., Krauss, M., López Herráez, D., van Gils, J., Slobodnik, J., Munthe, J., Gawlik, B.M., van Wezel, A., Schriks, M., Hollender, J., Tollefsen, K.E., Mekenyan, O., Dimitrov, S., Bunke, D., Cousins, I., Posthuma, L., van den Brink, P.J., López de Alda, M., Barceló, D., Faust, M., Kortenkamp, A., Scrimshaw, M., Ignatova, S.N., Engelen, G., Massmann, G., Lemkine, G., Teodorovic, I., Walz, K.-H., Dulio, V., Jonker, M.T.O., Jäger, F., Chipman, K., Falciani, F., Liska, I., Rooke, D., Zhang, X., Hollert, H., Vrana, B., Hilscherova, K., Kramer, K., Neumann, S., Hammerbacher, R., Backhaus, T., Mack, J., Segner, H., Escher, B., De Aragão Umbuzeiro, G., (2015):
The SOLUTIONS project: challenges and responses for present and future emerging pollutants in land and water resources management
Sci. Total Environ. 503-504 , 22 - 31
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Fetter, E., Smetanová, S., Baldauf, L., Lidzba, A., Altenburger, R., Schüttler, A., Scholz, S., (2015):
Identification and characterization of androgen-responsive genes in zebrafish embryos
Environ. Sci. Technol. 49 (19), 11789 - 11798
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Luckenbach, T., Küster, E., Busch, W., Scholz, S., Altenburger, R., (2015):
What determines chemical uptake by the zebrafish embryo model?
Toxicol. Lett. 238 (2, Suppl.), S54
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Massei, R., Vogs, C., Renner, P., Altenburger, R., Scholz, S., (2015):
Differential sensitivity in embryonic stages of the zebrafish (Danio rerio): The role of toxicokinetics for stage-specific susceptibility for azinphos-methyl lethal effects
Aquat. Toxicol. 166 , 36 - 41
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Riedl, J., Schreiber, R., Otto, M., Heilmeier, H., Altenburger, R., Schmitt-Jansen, M., (2015):
Metabolic effect level index links multivariate metabolic fingerprints to ecotoxicological effect assessment
Environ. Sci. Technol. 49 (13), 8096 - 8104
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Rotter, S., Gunold, R., Mothes, S., Paschke, A., Brack, W., Altenburger, R., Schmitt-Jansen, M., (2015):
Pollution-induced community tolerance to diagnose hazardous chemicals in multiple contaminated aquatic systems
Environ. Sci. Technol. 49 (16), 10048 - 10056
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Smetanová, S., Riedl, J., Zitzkat, D.P., Altenburger, R., Busch, W., (2015):
High-throughput concentration–response analysis for omics datasets
Environ. Toxicol. Chem. 34 (9), 2167 - 2180
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Vogs, C., Kühnert, A., Hug, C., Küster, E., Altenburger, R., (2015):
A toxicokinetic study of specifically acting and reactive organic chemicals for the prediction of internal effect concentrations in Scenedesmus vacuolatus
Environ. Toxicol. Chem. 34 (1), 100 - 111
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2014 (5)

Altenburger, R., Arrhenius, A., Backhaus, T., Coors, A., Faust, M., Zitzkat, D.P., (2014):
Ecotoxicological combined effects from chemical mixtures. Part 1: Relevance and adequate consideration in environmental risk assessment of plant protection products and biocides
Texte Umweltbundesamt 92/2013
Umweltbundesamt, Dessau-Roßlau, 203 pp.
full text (url)
Campos, B., Altenburger, R., Gómez, C., Lacorte, S., Piña, B., Barata, C., Luckenbach, T., (2014):
First evidence for toxic defense based on the multixenobiotic resistance (MXR) mechanism in Daphnia magna
Aquat. Toxicol. 148 , 139 - 151
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Escher, B.I., Allinson, M., Altenburger, R., Bain, P.A., Balaguer, P., Busch, W., Crago, J., Denslow, N.D., Dopp, E., Hilscherova, K., Humpage, A.R., Kumar, A., Grimaldi, M., Jayasinghe, B.S., Jarosova, B., Jia, A., Makarov, S., Maruya, K.A., Medvedev, A., Mehinto, A.C., Mendez, J.E., Poulsen, A., Prochazka, E., Richard, J., Schifferli, A., Schlenk, D., Scholz, S., Shiraishi, F., Snyder, S., Su, G., Tang, J.Y.M., van der Burg, B., van der Linden, S.C., Werner, I., Westerheide, S.D., Wong, C.K.C., Yang, M., Yeung, B.H.Y., Zhang, X., Leusch, F.D.L., (2014):
Benchmarking organic micropollutants in wastewater, recycled water and drinking water with in vitro bioassays
Environ. Sci. Technol. 48 (3), 1940 - 1956
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Faust, M., Vogs, C., Rotter, S., Wöltjen, J., Höllrigl-Rosta, A., Backhaus, T., Altenburger, R., (2014):
Comparative assessment of plant protection products: how many cases will regulatory authorities have to answer?
Environ. Sci. Eur. 26 , art. 11
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Pannier, A., Soltmann, U., Soltmann, B., Altenburger, R., Schmitt-Jansen, M., (2014):
Alginate/silica hybrid materials for immobilization of green microalgae Chlorella vulgaris for cell-based sensor arrays
J. Mat. Chem. B 45 (2), 7896 - 7909
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2013 (7)

Altenburger, R., Backhaus, T., Boedeker, W., Faust, M., Scholze, M., (2013):
Simplifying complexity : mixture toxicity assessment in the last 20 years
Environ. Toxicol. Chem. 32 (8), 1685 - 1687
full text (url)
Backhaus, T., Altenburger, R., Faust, M., Frein, D., Frische, T., Johansson, P., Kehrer, A., Porsbring, T., (2013):
Proposal for environmental mixture risk assessment in the context of the biocidal product authorization in the EU
Environ. Sci. Eur. 25 , art. 4
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Escher, B.I., van Daele, C., Dutt, M., Tang, J.Y.M., Altenburger, R., (2013):
Most oxidative stress response in water samples comes from unknown chemicals: the need for effect-based water quality trigger values
Environ. Sci. Technol. 47 (13), 7002 - 7011
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Kühnert, A., Vogs, C., Altenburger, R., Küster, E., (2013):
The internal concentration of organic substances in fish embryos - a toxicokinetic approach
Environ. Toxicol. Chem. 32 (8), 1819 - 1827
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Riedl, J., Rotter, S., Faetsch, S., Schmitt-Jansen, M., Altenburger, R., (2013):
Proposal for applying a component-based mixture approach for ecotoxicological assessment of fracturing fluids
Environ. Earth Sci. 70 (8), 3907 - 3920
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Rotter, S., Heilmeier, H., Altenburger, R., Schmitt-Jansen, M., (2013):
Multiple stressors in periphyton – comparison of observed and predicted tolerance responses to high ionic loads and herbicide exposure
J. Appl. Ecol. 50 (6), 1459 - 1468
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Vogs, C., Bandow, N., Altenburger, R., (2013):
Effect propagation in a toxicokinetic/toxicodynamic model explains delayed effects on the growth of unicellular green algae Scenedesmus vacuolatus
Environ. Toxicol. Chem. 32 (5), 1161 - 1172
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2012 (5)

Altenburger, R., Scholz, S., Schmitt-Jansen, M., Busch, W., Escher, B.I., (2012):
Mixture toxicity revisited from a toxicogenomic perspective
Environ. Sci. Technol. 46 (5), 2508 - 2522
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Frimmel, F.H., Ewers, U., Schmitt-Jansen, M., Gordalla, B., Altenburger, R., (2012):
Toxikologische Bewertung von Fracking-Fluiden
Wasser und Abfall 14 (6), 22 - 29
Gündel, U., Kalkhof, S., Zitzkat, D.P., von Bergen, M., Altenburger, R., Küster, E., (2012):
Concentration-response concept in ecotoxicoproteomics: effects of different phenanthrene concentrations to the zebrafish (Danio rerio) embryo proteome
Ecotox. Environ. Safe. 76 (1), 11 - 22
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Riedl, J., Kluender, C., Sans-Piché, F., Heilmeier, H., Altenburger, R., Schmitt-Jansen, M., (2012):
Spatial and temporal variation in metabolic fingerprints of field-growing Myriophyllum spicatum
Aquat. Bot. 102 , 34 - 43
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van Dam, J.W., Negri, A.P., Mueller, J.F., Altenburger, R., Uthicke, S., (2012):
Additive pressures of elevated sea surface temperatures and herbicides on symbiont-bearing foraminifera
PLoS One 7 (3), e33900
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2011 (7)

Altenburger, R., (2011):
Understanding combined effects for metal co-exposure in ecotoxicology
In: Sigel, A., Sigel, H., Sigel, R.K.O., (eds.)
Metal ions in toxicology: effects, interactions, interdependencies
Metal Ions in Life Sciences 8
Royal Society of Chemistry (RSC), Cambridge, p. 1 - 26
full text (url)
Kortenkamp, A., Altenburger, R., (2011):
Toxicity from combined exposure to chemicals
In: van Gestel, C.A.M., Jonker, M.J., Kammenga, J.E., Laskowski, R., Svendsen, C., (eds.)
Mixture toxicity: linking approaches from ecotoxicology and human toxicology
CRC Press, Boca Raton, FL, p. 95 - 120
Küster, A., Altenburger, R., (2011):
Characeen als Objekte ökotoxikologischer Untersuchungen
Ber. Bot. Arbeitsgem. Südwestdeutschland (Beiheft 3), 31 - 36
Rotter, S., Sans-Piché, F., Streck, G., Altenburger, R., Schmitt-Jansen, M., (2011):
Active bio-monitoring of contamination in aquatic systems - an in situ translocation experiment applying the PICT concept
Aquat. Toxicol. 101 (1), 228 - 236
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Schreiber, R., Gündel, U., Franz, S., Küster, A., Rechenberg, B., Altenburger, R., (2011):
Using the fish plasma model for comparative hazard identification for pharmaceuticals in the environment by extrapolation from human therapeutic data
Regul. Toxicol. Pharmacol. 61 (3), 261 - 275
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Schreiber, R., Küster, A., Feiler, U., Grote, M., Altenburger, R., (2011):
A non-invasive observation parameter to complement sediment bioassays using Myriophyllum aquaticum
J. Soils Sediments 11 (8), 1419 - 1431
full text (url)
Siegert, F., Erdmann, F., Schwan, G., Scholz, S., Briel, D., Altenburger, R., Nieber, K., (2011):
Pharmacological and cytotoxic effects of new selective PDE10A ligands
Naunyn-Schmiedebergs Arch. Pharmacol. 383 (Suppl. 1), 21 - 21
full text (url)

2001 - 2010

2010 (10)

Altenburger, R., Berns, A.E., Bittens, M., Brack, W., Burauel, P., Centler, F., Daus, B., Goss, K.-U., Harms, H., Kopinke, F.-D., Kühnel, D., Liess, M., Mackenzie, K., Miltner, A., Thullner, M., Wennrich, R., Wick, L.Y., (2010):
Chemicals in the environment (CITE). Report of the First Annual Conference of the Helmholtz research topic CITE
UWSF 22 (4), 502 - 506
full text (url)
Altenburger, R., Krüger, A., Eisenträger, A., (2010):
Proposing a pH stabilised nutrient medium for algal growth bioassays
Chemosphere 78 (7), 864 - 870
full text (url)
Bandow, N., Altenburger, R., Brack, W., (2010):
Application of nd-SPME to determine freely dissolved concentrations in the presence of green algae and algae-water partition coefficients
Chemosphere 79 (11), 1070 - 1076
full text (url)
Daus, B., Weiß, H., Altenburger, R., (2010):
Uptake and toxicity of hexafluoroarsenate in aquatic organisms
Chemosphere 78 (3), 307 - 312
full text (url)
Daus, B., Weiß, H., Wennrich, R., Altenburger, R., (2010):
Are fluorine containing arsenic species an environmental problem?
In: Jean, J.-S., Bundschuh, J., Bhattacharya, P., (eds.)
Arsenic in geosphere and human diseases; Arsenic 2010: Proceedings of the Third International Congress on Arsenic in the Environment
Taylor & Francis, London, p. 376 - 377
Gündel, U., Kalkhof, S., von Bergen, M., Altenburger, R., Küster, E., (2010):
Concentration-response concept in ecotoxicoproteomics: an optimised design for the detection of robust chemical stress associated protein markers: Effects of different concentrations of phenanthren to the proteome of Danio rerio embryos
Comp. Biochem. Physiol. A-Mol. Integr. Physiol. 157 (Suppl. 1), S42 - S43
full text (url)
Hanisch, K., Küster, E., Altenburger, R., Gündel, U., (2010):
Proteomic signatures of the zebrafish (Danio rerio) embryo: sensitivity and specificity in toxicity assessment of chemicals
International Journal of Proteomics 2010 , Article ID 630134 - 13
full text (url)
Sans-Piché, F., Kluender, C., Altenburger, R., Schmitt-Jansen, M., (2010):
Anchoring metabolic changes to phenotypic effects in the chlorophyte Scenedesmus vacuolatus under chemical exposure
Mar. Environ. Res. 69 (Suppl. 1), 528 - 530
full text (url)
Scholz, S., Schirmer, K., Altenburger, R., (2010):
Pharmaceutical contaminants in urban water cycles - a discussion of novel concepts for environmental risk assessment
In: Fata-Kassinos, D., Bester, K., Kümmerer, K., (eds.)
Xenobiotics in the urban water cycle: mass flows, environmental processes and mitigation strategies
Environ. Pollut. 16
Springer, Heidelberg, p. 227 - 244
full text (url)
Schulze, T., Weiss, S., Schymanski, E., von der Ohe, P.C., Schmitt-Jansen, M., Altenburger, R., Streck, G., Brack, W., (2010):
Identification of a phytotoxic photo-transformation product of diclofenac using effect-directed analysis
Environ. Pollut. 158 (5), 1461 - 1466
full text (url)

2009 (8)

Altenburger, R., Greco, W.R., (2009):
Extrapolation concepts for dealing with multiple contamination in environmental risk assessment
Integr. Environ. Assess. Manag. 5 (1), 62 - 68
full text (url)
Altenburger, R., Gündel, U., Ali-Aycheh, M., Hanisch, K., Küster, A., Rechenberg, B., Schreiber, R., (2009):
Models for extrapolation of long-term effects of pharmaceuticals in the environment using therapeutic information
Toxicol. Lett. 189 (Suppl. 1), S191 - S192
full text (url)
Bandow, N., Altenburger, R., Lübcke-von Varel, U., Paschke, A., Streck, G., Brack, W., (2009):
Partitioning-based dosing: an approach to include bioavailability in the effect-directed analysis of contaminated sediment samples
Environ. Sci. Technol. 43 (10), 3891 - 3896
full text (url)
Bandow, N., Altenburger, R., Streck, G., Brack, W., (2009):
Effect-directed analysis of contaminated sediments with partition-based dosing using green algae cell multiplication inhibition
Environ. Sci. Technol. 43 (19), 7343 - 7349
full text (url)
Kluender, C., Sans-Piché, F., Riedl, J., Altenburger, R., Härtig, C., Laue, G., Schmitt-Jansen, M., (2009):
A metabolomics approach to assessing phytotoxic effects on the green alga Scenedesmus vacuolatus
Metabolomics 5 (1), 59 - 71
full text (url)
Rodil, R., Moeder, M., Altenburger, R., Schmitt-Jansen, M., (2009):
Photostability and phytotoxicity of selected sunscreen agents and their degradation mixtures in water
Anal. Bioanal. Chem. 395 (5), 1513 - 1524
full text (url)
Schreiber, R., Altenburger, R., Paschke, A., Schüürmann, G., Küster, E., (2009):
A novel in vitro system for the determination of bioconcentration factors and the internal dose in zebrafish (Danio rerio) eggs
Chemosphere 77 (7), 928 - 933
full text (url)
Schwab, K., Altenburger, R., Lübcke-von Varel, U., Streck, G., Brack, W., (2009):
Effect-directed analysis of sediment-associated algal toxicants at selected hot spots in the river Elbe basin with a special focus on bioaccessibility
Environ. Toxicol. Chem. 28 (7), 1506 - 1517
full text (url)

2008 (9)

Altenburger, R., Schmitt-Jansen, M., Riedl, J., (2008):
Bioassays with unicellular algae: deviations from exponential growth and its implications for toxicity test results
J. Environ. Qual. 37 (1), 16 - 21
full text (url)
Franz, S., Altenburger, R., Heilmeier, H., Schmitt-Jansen, M., (2008):
What contributes to the sensitivity of microalgae to triclosan?
Aquat. Toxicol. 90 (2), 102 - 108
full text (url)
Küster, E., Altenburger, R., (2008):
Oxygen decline in biotesting of environmental samples - Is there a need for consideration in the acute zebrafish embryo assay?
Environ.Toxicol. 23 (6), 745 - 750
full text (url)
Luckenbach, T., Altenburger, R., Epel, D., (2008):
Teasing apart activities of different types of ABC efflux pumps in bivalve gills using the concepts of independent action and concentration addition
Mar. Environ. Res. 66 (1), 75 - 76
full text (url)
McClellan, K., Altenburger, R., Schmitt-Jansen, M., (2008):
Pollution-induced community tolerance as a measure of species interaction in toxicity assessment
J. Appl. Ecol. 45 (5), 1514 - 1522
full text (url)
Posthuma, L., Richards, S.M., de Zwart, D., Dyer, S.D., Sibley, P.K., Hickey, C.W., Altenburger, R., (2008):
Mixture extrapolation approaches
In: Solomon, K.R., Brock, T.C.M., de Zwart, D., Dyer, S.D., Posthuma, L., Richards, S.M., Sanderson, H., Sibley, P.K., van den Brink, P.J., (eds.)
Extrapolation practice for ecotoxicological effect characterization of chemicals
CRC Press, Boca Raton, FL, p. 135 - 185
Schmitt-Jansen, M., Altenburger, R., (2008):
Community-level microalgal toxicity assessment by multiwavelength-excitation PAM fluorometry
Aquat. Toxicol. 86 (1), 49 - 58
full text (url)
Schmitt-Jansen, M., Veit, U., Dudel, G., Altenburger, R., (2008):
An ecological perspective in aquatic ecotoxicology: approaches and challenges
Basic Appl. Ecol. 9 (4), 337 - 345
full text (url)
Schreiber, R., Altenburger, R., Paschke, A., Küster, E., (2008):
How to deal with lipophilic and volatile organic substances in microtiter plate assays
Environ. Toxicol. Chem. 27 (8), 1676 - 1682
full text (url)

2007 (11)

Adler, N.E., Schmitt-Jansen, M., Altenburger, R., (2007):
Flow cytometry as a tool to study phytotoxic modes of action
Environ. Toxicol. Chem. 26 (2), 297 - 306
full text (url)
Bakker, J.F., Belzunce-Segarra, M.J., Castro, R., van de Heuvel-Greve, M., Klamer, H.J.C., Brack, W., Altenburger, R., Poulsen, V., Thomas, K.V., Leonards, P.E.G., (2007):
Effect directed analysis and toxicity identification evaluation
In: Barceló, D., Petrovic, M., (eds.)
Sediment quality and impact assessment of pollutants
Sustainable Management of Sediment Resources Vol. 1
Elsevier, Amsterdam, p. 163 - 214
full text (url)
Gündel, U., Benndorf, D., von Bergen, M., Altenburger, R., Küster, E., (2007):
Vitellogenin cleavage products as indicators for toxic stress in zebra fish embryos: a proteomic approach
Proteomics 7 (24), 4541 - 4554
full text (url)
Küster, A., Altenburger, R., (2007):
Development and validation of a new fluorescence-based bioassay for aquatic macrophyte species
Chemosphere 67 (1), 194 - 201
full text (url)
Küster, A., Pohl, K., Altenburger, R., (2007):
A fluorescence-based bioassay for aquatic macrophytes and its suitability for effect analysis of non-photosystem II inhibitors
Environ. Sci. Pollut. Res. 14 (6), 377 - 383
full text (url)
Küster, E., Altenburger, R., (2007):
Suborganismic and organismic effects of aldicarb and its metabolite aldicarb-sulfoxide to the zebrafish embryo (Danio rerio)
Chemosphere 68 (4), 751 - 760
full text (url)
Pohl, K., Altenburger, R., Küster, A., (2007):
Entwicklung und Etablierung eines Kurzzeit-Biotestsystems für aquatische Makrophyten
Erweiterte Zusammenfassungen der Jahrestagung 2006 der Deutschen Gesellschaft für Limnologie (DGL) und der deutschen und österreichischen Sektion der Societas Internationalis Limnologiae (SIL). Dresden, 25. - 29.09.2006
Deutsche Gesellschaft für Limnologie, Werder, S. 368 - 372
Riedl, J., Altenburger, R., (2007):
Physicochemical substance properties as indicators for unreliable exposure in microplate-based bioassays
Chemosphere 67 (11), 2210 - 2220
full text (url)
Schmitt-Jansen, M., Altenburger, R., (2007):
The use of pulse-amplitude modulated (PAM) fluorescence-based methods to evaluate effects of herbicides in microalgal systems of different complexity
Toxicol. Environ. Chem. 89 (4), 651 - 667
full text (url)
Schmitt-Jansen, M., Bartels, P., Adler, N., Altenburger, R., (2007):
Phytotoxicity assessment of diclofenac and its phototransformation products
Anal. Bioanal. Chem. 387 (4), 1389 - 1396
full text (url)
Tammer, B., Lehmann, I., Nieber, K., Altenburger, R., (2007):
Combined effects of mycotoxin mixtures on human T cell function
Toxicol. Lett. 170 (2), 124 - 133
full text (url)

2006 (2)

Altenburger, R., Brack, W., Greco, W.R., Grote, M., Jung, K., Ovari, A., Riedl, J., Schwab, K., Küster, E., (2006):
On the mode of action of N-phenyl-2-naphthylamine in plants
Environ. Sci. Technol. 40 (19), 6163 - 6169
full text (url)
Küster, E., Altenburger, R., (2006):
Comparison of cholin- and carboxylesterase enzyme inhibition and visible effects in the zebra fish embryo bioassay under short-term paraoxon-methyl exposure
Biomarkers 11 (4), 341 - 354
full text (url)

2005 (14)

Altenburger, R., Schmitt, H., Schüürmann, G., (2005):
Algal toxicity of nitrobenzenes: combined effect analysis as a pharmacological probe for similar modes of interaction
Environ. Toxicol. Chem. 24 (2), 324 - 333
full text (url)
Grote, M., Altenburger, R., Brack, W., Moschütz, S., Mothes, S., Michael, C., Narten, G.-B., Paschke, A., Schirmer, K., Walter, H.A., Wennrich, R., Wenzel, K.-D., Schüürmann, G., (2005):
Ecotoxicological profiling of transect river Elbe sediments
Acta Hydrochim. Hydrobiol. 33 (5), 555 - 569
full text (url)
Grote, M., Brack, W., Altenburger, R., (2005):
Identification of toxicants from marine sediment using effect-directed analysis
Environ.Toxicol. 20 (5), 475 - 486
full text (url)
Grote, M., Brack, W., Walter, H.A., Altenburger, R., (2005):
Confirmation of cause-effect relationships using effect-directed analysis for complex environmental samples
Environ. Toxicol. Chem. 24 (6), 1420 - 1427
full text (url)
Grote, M., Brack, W., Walter, H.A., Altenburger, R., (2005):
Light as a confounding factor for toxicity assessment of complex contaminated sediments
Environ. Toxicol. Chem. 24 (12), 3143 - 3152
full text (url)
Grote, M., Schüürmann, G., Altenburger, R., (2005):
Modeling photoinduced algal toxicity of polycyclic aromatic hydrocarbons
Environ. Sci. Technol. 39 (11), 4141 - 4149
full text (url)
Küster, E., Dorusch, F., Altenburger, R., (2005):
Toxizität von Schwefelwasserstoff (H₂S) auf die Biotestorganismen Vibrio fischeri und Daphnia magna
Tagungsbericht 2004 der Deutschen Gesellschaft für Limnologie e.V. (DGL) und der Deutschsprachigen Sektion der Societas Internationalis Limnologiae (SIL). Potsdam, 20. - 24.09.2004
Deutsche Gesellschaft für Limnologie, Berlin, S. 561 - 565
Küster, E., Dorusch, F., Altenburger, R., (2005):
Effects of hydrogen sulfide to Vibrio fischeri, Scenedesmus vacuolatus, and Daphnia magna
Environ. Toxicol. Chem. 24 (10), 2621 - 2629
full text (url)
Olajire, A.A., Altenburger, R., Küster, E., Brack, W., (2005):
Chemical and ecotoxicological assessment of polycyclic aromatic hydrocarbon-contaminated sediments of the Niger Delta, Southern Nigeria
Sci. Total Environ. 340 (1-3), 123 - 136
full text (url)
Schmitt-Jansen, M., Altenburger, R., (2005):
Lassen sich Ergebnisse aus ökotoxikologischen Einzelartentests auf aquatische Lebensgemeinschaften extrapolieren?
Tagungsbericht 2004 der Deutschen Gesellschaft für Limnologie e.V. (DGL) und der Deutschsprachigen Sektion der Societas Internationalis Limnologiae (SIL). Potsdam, 20. - 24.09.2004
Deutsche Gesellschaft für Limnologie, Berlin, S. 556 - 560
Schmitt-Jansen, M., Altenburger, R., (2005):
Predicting and observing responses of algal communities to photosystem II-herbicide exposure using pollution-induced community tolerance and species-sensitivity distributions
Environ. Toxicol. Chem. 24 (2), 304 - 312
full text (url)
Schmitt-Jansen, M., Altenburger, R., (2005):
Toxic effects of isoproturon on periphyton communities - a microcosm study
Estuar. Coast. Shelf Sci. 62 (3), 539 - 545
full text (url)
von der Ohe, P.C., Kühne, R., Ebert, R.U., Altenburger, R., Liess, M., Schüürmann, G., (2005):
Structural alerts - a new classification model to discriminate excess toxicity from narcotic effect levels of organic compounds in the acute daphnid assay
Chem. Res. Toxicol. 18 (3), 536 - 555
full text (url)
Wollin, K.M., Altenburger, R., Altmayer, M., Dieter, H.H., Moll, B., Six, E., von der Trenck, K.T., (2005):
(ECO)toxicological insignificance thresholds for risk assessment of polluted groundwater
Naunyn-Schmiedebergs Arch. Pharmacol. 371 (Suppl. 1), R133 - R134

2004 (9)

Altenburger, R., Walter, H., Grote, M., (2004):
What contributes to the combined effect of a complex mixture?
Environ. Sci. Technol. 38 (23), 6353 - 6362
full text (url)
Bopp, S., Schirmer, M., Russold, S., Altenburger, R., Schirmer, K., (2004):
Combined chemical/biological monitoring as part of assessing natural attenuation at a BTEX-contaminated megasite
In: Magar, V.S., Kelley, M.E., (eds.)
7th International In Situ and On-Site Bioremediation Symposium, Orlando/USA, 2.-5.6.2003
Battelle Press, Columbus, OH, p. Paper H32
Grote, M., Altenburger, R., Brack, W., Möckel, C., Moschütz, S., Mothes, S., Michael, C., Narten, G.-B., Paschke, A., Schirmer, K., Walter, H., Wennrich, R., Wenzel, K.-D., Schüürmann, G., (2004):
Identifizierung und Analyse des ökotoxischen Potentials von Flusssedimenten als Folge der durch Hochwasser mobilisierten Kontamination
In: Geller, W., Ockenfeld, K., Böhme, M., Knöchel, A., (Hrsg.)
Schadstoffbelastung nach dem Elbe-Hochwasser 2002. Endbericht des Ad-hoc-Verbundprojekts
UFZ Leipzig-Halle GmbH, Magdeburg, S. 314 - 329
Grote, M., Walter, H., Altenburger, R., (2004):
Toxizitätsuntersuchungen von Elbsedimenten in Kontakttesten mit Lemna minor und Danio rerio
Statusseminar Sedimentskontakttests : 24./25. März 2004 in Koblenz
Veranstaltungen / BfG 5/2004
Bundesanstalt für Gewässerkunde, Koblenz, S. 25 - 35
Krumm, B., Altenburger, R., Nieber, K., Lehmann, I., (2004):
Low concentration of mycotoxins with weak effects as single compounds mediate strong inhibition of IFN-gamma release when exposed together
Immunobiology 209 (4-6), 470
full text (url)
Küster, E., Dorusch, F., Altenburger, R., (2004):
Ökotoxikologische Verfahren der Wirkungsanalyse für das Management von Grundwasser-Kontaminationen: Fallbeispiel quartärer Grundwasserleiter in Bitterfeld-Süd
In: Weiß, H., Teutsch, G., Daus, B., (Hrsg.)
SAFIRA (Sanierungsforschung in regional kontaminierten Aquiferen)
UFZ-Bericht 13/2004
UFZ Leipzig-Halle GmbH, Leipzig, S. 287 - 316
full text (pdf)
Küster, E., Dorusch, F., Vogt, C., Weiß, H., Altenburger, R., (2004):
On line biomonitors used as a tool for toxicity reduction evaluation of in situ groundwater remediation techniques
Biosens. Bioelectron. 19 (12), 1711 - 1722
full text (url)
Schmitt-Jansen, M., Küster, A., Altenburger, R., (2004):
Untersuchung schadstofftoleranter Aufwuchsgemeinschaften als ein Instrument zur Bewertung von Schadstoffen in Gewässern
Tagungsbericht 2002 der Deutschen Gesellschaft für Limnologie (DGL) und der deutschen und österreichischen Sektion der Societas Internationionalis Limnologiae (SIL). Band II, Braunschweig, 30.9.-4.10.2002
Deutsche Gesellschaft für Limnologie, Werder, p. 621 - 626
Schmitt-Jansen, M., Reiners, S., Altenburger, R., (2004):
Biozönotische Testverfahren (PICT-Konzept). Analyse von Schadstoff-induzierten Effekten in Gewässern mit autotrophen Aufwuchszönosen
UWSF 16 (2), 85 - 91
full text (url)

2003 (12)

Altenburger, R., Brack, W., Grote, M., Moschütz, S., Paschke, A., Schirmer, K., Walter, H., Wenzel, K., Schüürmann, G., (2003):
Identifizierung und Analyse des ökotoxikologischen Potentials von Flußsedimenten als Folge der durch Hochwasser mobilisierten Kontaminationen
Schadstoffbelastung im Mulde- und Elbe-Einzugsgebiet nach dem Augusthochwasser 2002,
Ergebnisse und Forschungsbedarf, Tagungsband. Statusseminar des BMBF-Ad-hoc-Verbundprojektes, Freiberg, 27.-29. August 2003
UFZ Leipzig-Halle GmbH, Magdeburg, p. 9 - 12
Altenburger, R., Nendza, M., Schüürmann, G., (2003):
Mixture toxicity and its modeling by quantitative structure-activity relationships
Environ. Toxicol. Chem. 22 (8), 1900 - 1915
full text (url)
Altenburger, R., Schmitt-Jansen, M., (2003):
Predicting toxic effects of contaminants in ecosystems using single species investigations
In: Breure, A.M., Markert, B.A., Zechmeister, H.G., (eds.)
Bioindicators & biomonitors. Principles, concepts and applications
Trace Metals and other Contaminants in the Environment 6
Elsevier, Amsterdam, p. 153 - 198
full text (url)
Altenburger, R., Segner, H., van der Oost, R., (2003):
Biomarkers and PAHs - prospects for the assessment of exposure and effects in aquatic systems
In: Douben, P.E.T., (ed.)
PAHs: an ecotoxicological perspective
Ecological and Environmental Toxicology Series
Wiley, Chichester, p. 297 - 328
Backhaus, T., Altenburger, R., Arrhenius, A., Blanck, H., Faust, M., Finizio, A., Gramatica, P., Grote, M., Junghans, M., Meyer, W., Pavan, M., Porsbring, T., Scholze, M., Todeschini, R., Vighi, M., Walter, H., Grimme, L.H., (2003):
The BEAM-project: prediction and assessment of mixture toxicities in the aquatic environment
Cont. Shelf Res 23 (17-19), 1757 - 1769
full text (url)
Brack, W., Altenburger, R., Küster, E., Meissner, B., Wenzel, K.-D., Schüürmann, G., (2003):
Identification of toxic products of anthracene photomodification in simulated sunlight
Environ. Toxicol. Chem. 22 (10), 2228 - 2237
full text (url)
Faust, M., Altenburger, R., Backhaus, T., Blanck, H., Boedeker, W., Gramatica, P., Hamer, V., Scholze, M., Vighi, M., Grimme, L.H., (2003):
Joint algal toxicity of 16 dissimilarly acting chemicals is predictable by the concept of independent action
Aquat. Toxicol. 63 (1), 43 - 63
full text (url)
Küster, E., Dorusch, F., Meißner, B., Weiß, H., Schüürmann, G., Altenburger, R., (2003):
Toxizitätsreduktion durch (Grundwasser-) Sanierung? Erfolgskontrolle von In-situ-Grundwasser- Sanierungsverfahren mithilfe von kontinuierlichen und diskontinuierlichen Biotests
Grundwasser 8 (1), 32 - 40
full text (url)
Küster, E., Dorusch, F., Weiß, H., Altenburger, R., (2003):
Controlling (groundwater-) remediation success via on line biomonitoring or how toxic is remediated groundwater?
ConSoil 2003 : proceedings of the 8th International FZK/TNO Conference on Contaminated Soil, ICC Gent, Belgium, 12 - 16 May 2003
F&U confirm, Leipzig, p. 3305 - 3314
Küster, E., Dorusch, F., Weiß, H., Schüürmann, G., Altenburger, R., (2003):
Beurteilung der Entgiftung von Grundwasser durch Sanierungsverfahren mittels kontinuierlicher biologischer Überwachung
In: Foth, H., (Hrsg.)
Risk assessment and management of large contamination sites. Gefahrenabschätzung und Handhabung großflächiger Kontaminationen. Proceedingsband zum Kongress an der Martin-Luther-Universität Halle-Wittenberg, 22. - 24. Februar 2002
S. 41 - 45
Schirmer, K., Altenburger, R., Bopp, S., Weiß, H., (2003):
Toxikologische Überwachung beim Einsatz von "Natural Attenuation" als Sanierungsoption
In: Foth, H., (Hrsg.)
Risk assessment and management of large contamination sites. Gefahrenabschätzung und Handhabung großflächiger Kontaminationen. Proceedingsband zum Kongress an der Martin-Luther-Universität Halle-Wittenberg, 22. - 24. Februar 2002
S. 33 - 36
Vighi, M., Altenburger, R., Arrhenius, A., Backhaus, T., Bödeker, W., Blanck, H., Consolaro, F., Faust, M., Finizio, A., Froehner, K., Gramatica, P., Grimme, L.H., Grönvall, F., Hamer, V., Scholze, M., Walter, H., (2003):
Water quality objectives for mixtures of toxic chemicals: problems and perspectives
Ecotox. Environ. Safe. 54 (2), 139 - 150
full text (url)

2002 (7)

Altenburger, R., (2002):
Predicting toxic effects of contaminants in ecosystems using single species investigations
Habilitation, Universität Bremen, Fachbereich Biologie und Chemie
206 pp.
Brack, W., Altenburger, R., (2002):
Effektorientierte Identifikation toxischer Verbindungen
Mitteilungen der Fachgruppe Umweltchemie und Ökotoxikologie / Gesellschaft Deutscher Chemiker 8 , 6 - 8
Brack, W., Altenburger, R., Dorusch, F., Hubert, A., Möder, M., Morgenstern, P., Moschütz, S., Mothes, S., Schirmer, K., Wennrich, R., Wenzel, K.-D., Schüürmann, G., (2002):
Hochwasser 2002 - Chemische und toxische Belastung überschwemmter Gemeinden im Raum Bitterfeld
UWSF 14 (4), 213 - 220
full text (url)
Cleuvers, M., Altenburger, R., Ratte, H.T., (2002):
Combination effect of light and toxicity in algal tests
J. Environ. Qual. 31 (2), 539 - 547
full text (url)
Meene, R., Schüürmann, G., Altenburger, R., (2002):
pH-abhängige Algentoxizität von Phenolderivaten
Mitteilungen der Fachgruppe Umweltchemie und Ökotoxikologie / Gesellschaft Deutscher Chemiker 8 , 9 - 11
Schirmer, K., Altenburger, R., Bopp, S.K., Weiß, H., (2002):
Toxicological monitoring for the assessment of natural attenuation as a remediation option
International conference on Risk Assessment of Large Contaminated Sites, Halle, Germany, 22.-23.2.2002
Walter, H., Consolaro, F., Gramatica, P., Scholze, M., Altenburger, R., (2002):
Mixture toxicity of priority pollutants at no observed effect concentrations (NOECs)
Ecotoxicology 11 (5), 299 - 310
full text (url)

2001 (5)

Faust, M., Altenburger, R., Backhaus, T., Blanck, H., Bödeker, W., Gramatica, P., Hamer, V., Scholze, M., Vighi, M., Grimme, L.H., (2001):
Predicting the joint algal toxicity of multi-component s-triazine mixtures at low-effect concentrations of individual toxicants
Aquat. Toxicol. 56 (1), 13 - 32
full text (url)
Knops, M., Altenburger, R., Segner, H., (2001):
Alterations of physiological energetics, growth and reproduction of Daphnia magna under toxicant stress
Aquat. Toxicol. 53 (2), 79 - 90
full text (url)
Küster, E., Dorusch, F., Weiß, H., Altenburger, R., (2001):
TRE-Toxicity-Reduction-Evaluation - Approaches for continuous effect monitoring of in situ groundwater remediation techniques
11th Annual Meeting of the Society of Environmental Toxicology and Chemistry (SETAC) Europe, Madrid, Spain, 6-10 May 2001
SETAC Europe, Brussels,
Scholze, M., Boedeker, W., Faust, M., Backhaus, T., Altenburger, R., Grimme, L.H., (2001):
A general best-fit method for concentration-response curves and the estimation of low-effect concentrations
Environ. Toxicol. Chem. 20 (2), 448 - 457
full text (url)
Segner, H., Altenburger, R., Jung, K., Schüürmann, G., (2001):
Ecotoxicity characterization of seepage waters from a Theisenschlamm pond discharging into riverine system
In: Daus, B., Weiß, H., (eds.)
Fine-grained residues from copper smelting and their environmental impacts
UFZ-Bericht 22/2001
UFZ Leipzig-Halle GmbH, Leipzig, p. 59 - 69
full text (pdf)

1997 - 2000

2000 (11)

Altenburger, R., Backhaus, T., Boedeker, W., Faust, M., Scholze, M., Grimme, L.H., (2000):
Predictability of the toxicity of multiple chemical mixtures to Vibrio fischeri: Mixtures composed of similarly acting chemicals
Environ. Toxicol. Chem. 19 (9), 2341 - 2347
full text (url)
Altenburger, R., Backhaus, T., (2000):
Exposition und Toxizität - Der Faktor Zeit in Routinebiotests
In: Mücke, W., Link, M., (Hrsg.)
Biotests in der Praxis - Status und Perspektiven in Methodik und Anwendung
TU München, Institut für Toxikologie und Umwelthygiene; Dr. Bruno Lange GmbH Düsseldorf, S. 61 - 74
Altenburger, R., Segner, H., (2000):
Anwendungen biologischer Testverfahren für ökotoxikologische Wirkungsanalysen
In: Fomin, A., Arndt, U., Elsner, D., Klumpp, A., (Hrsg.)
Bioindikation: Biologische Testverfahren. Beiträge und Diskussion - 2. Hohenheimer Workshop zur Bioindikation am Kraftwerk Altbach-Deizisau, 6.4.1998
Heimbach, Stuttgart, S. 23 - 31
Backhaus, T., Altenburger, R., Boedeker, W., Faust, M., Scholze, M., Grimme, L.H., (2000):
Predictability of the toxicity of multiple chemical mixtures of dissimilarly acting chemicals to Vibrio fischeri
Environ. Toxicol. Chem. 19 (9), 2348 - 2356
full text (url)
Brack, W., Altenburger, R., (2000):
Identifikation giftiger Inhaltsstoffe - ein wichtiger Schritt zur Gefährdungsabschätzung und Sanierung
UFZ-Jahresbericht '98-'99
UFZ Leipzig-Halle GmbH, Leipzig, S. 26 - 34
full text (pdf)
Brack, W., Altenburger, R., Ensenbach, U., Nehls, S., Segner, H., (2000):
Biotestorientierte Identifikation toxischer organischer Sedimentinhaltstoffe - Ein Beitrag zur Risikoanalyse komplexer Kontaminationen am Beispiel des Spittelwassers. Mitteilung Nr. 22. Sedimentbewertung in europäischen Flußgebieten. Beiträge zum internationalen Symposium vom 12.-14. April 1999
"Sedimentbewertung in europäischen Flußgebieten", Koblenz, 12.-14.4.1999
Bundesanstalt für Gewässerkunde, Koblenz, p. 135 - 141
Brack, W., Altenburger, R., Ensenbach, U., Nehls, S., Segner, H., Schüürmann, G., (2000):
Wirkungsorientierte Identifikation toxischer organischer Inhaltsstoffe in Flußsedimenten
In: Friese, K., Witter, B., Miehlich, G., Rode, M., (Hrsg.)
Stoffhaushalt von Auenökosystemen. Böden und Hydrologie, Schadstoffe, Bewertungen
Springer, Berlin, Heidelberg, New York, S. 337 - 346
full text (url)
Faust, M., Altenburger, R., Backhaus, T., Boedeker, W., Scholze, M., Grimme, L.H., (2000):
Predictive assessment of the aquatic toxicity of multiple chemical mixtures
J. Environ. Qual. 29 (4), 1063 - 1068
full text (url)
Grimme, L.H., Altenburger, R., Backhaus, T., Faust, M., Bödeker, W., Scholze, M., (2000):
Kombinationswirkungen von Umweltchemikalien in der Ökotoxikologie. Konzepte für die Vorhersage und ihre experimentelle Prüfung
UWSF 12 , 226 - 234
full text (url)
Hafner, C., Jung, K., Gehre, M., Altenburger, R., Schüürmann, G., (2000):
Isotopenmassenspektrometrische ¹³C/¹⁵N-Traceruntersuchungen zur Wirkung von Chlororganika auf höhere Pflanzen am Beispiel von Pentachlorphenol
In: Fomin, A., Arndt, U., Elsner, D., Klumpp, A., (Hrsg.)
Bioindikation: Biologische Testverfahren. Beiträge und Diskussion - 2. Hohenheimer Workshop zur Bioindikation am Kraftwerk Altbach-Deizisau, 6.4.1998
Heimbach, Stuttgart, S. 199 - 204
Schmitt, H., Altenburger, R., Jastorff, B., Schüürmann, G., (2000):
Quantitative structure-activity analysis of the algae toxicity of nitroaromatic compounds
Chem. Res. Toxicol. 13 (6), 441 - 450
full text (url)

1999 (5)

Brack, W., Altenburger, R., Ensenbach, U., Möder, M., Segner, H., Schüürmann, G., (1999):
Bioassay-directed identification of organic toxicants in river sediment in the industrial region of Bitterfeld (Germany) - a contribution to hazard assessment
Arch. Environ. Contam. Toxicol 37 (2), 164 - 174
full text (url)
Brack, W., Altenburger, R., Ensenbach, U., Segner, H., Schüürmann, G., (1999):
Biotest-orientierte Identifikation toxischer Inhaltsstoffe in Sedimenten des Elbeeinzugsgebiets
In: Friese, K., Kirschner, K., Witter, B., (Hrsg.)
Stoffhaushalt von Auenökosystemen der Elbe und ihrer Nebenflüsse : Nähr- und Schadstoffe - Ökotoxikologie - Belastbarkeit von Flußauen. Workshop, 1. bis 3. Februar 1999 im UFZ-Umweltforschungszentrum Leipzig-Halle, Sektion Gewässerforschung Magdeburg
UFZ-Bericht 1/1999
UFZ Leipzig-Halle GmbH, Leipzig, S. 41 - 41
full text (pdf)
Kortenkamp, A., Altenburger, R., (1999):
Approaches to assessing combination effects of oestrogenic environmental pollutants
Sci. Total Environ. 233 (1-3), 131 - 140
full text (url)
Praszczyk, B., Altenburger, R., Oehlmann, J., Markert, B., Schüürmann, G., (1999):
Brauchen wir einen Biotest mit höheren Pflanzen in der aquatischen Toxikologie?
In: Oehlmann, J., Markert, B., (Hrsg.)
Ökotoxikologie: Ökosystemare Ansätze und Methoden
ecomed, Landsberg am Lech, S. 151 - 163
Schüürmann, G., Altenburger, R., Segner, H., Lenoir, D., Metzger, J.O., Schrenk, D., (1999):
Umweltchemie 1998
Nachr. Chem., Tech. Lab. 47 (3), 291 - 302
full text (url)

1998 (5)

Brack, W., Altenburger, R., Ensenbach, U., Nehls, S., Segner, H., Schüürmann, G., (1998):
Identifikation ökotoxikologisch wirksamer Substanzen in Sedimenten des Spittelwassers
In: Geller, W., Punčochář, P., Bornhöft, D., Bouček, J., Feldmann, H., Guhr, H., Mohaupt, V., Simon, M., Smrtˇák, J., Spoustová, J., Uhlmann, O., (Hrsg.)
Gewässerschutz im Einzugsgebiet der Elbe. 8. Magdeburger Gewässerschutzseminar, Oktober 1998, Karlsbad (Tschechien)
B.G. Teubner, Stuttgart, Leipzig, S. 149 - 150
full text (url)
Ensenbach, U., Altenburger, R., Behrens, A., Brack, W., Knops, M., Navas, J.M., Nehls, S., Schrag, B., Segner, H., Sturm, A., Walter, H., Schüürmann, G., (1998):
Ökotoxikologische Analyse komplexer Stoffgemische
Tagungsbericht 1997 der Deutschen Gesellschaft für Limnologie (DGL) und der deutschen und österreichischen Sektion der Societas Internationalis Limnologiae (SIL). Band II, Frankfurt am Main, 22. - 26.9.1997
Deutsche Gesellschaft für Limnologie, Krefeld, p. 882 - 885
Ensenbach, U., Altenburger, R., Brack, W., Paschke, A., Popp, P., Segner, H., Wennrich, R., Schüürmann, G., (1998):
Ökotoxikologische Charakterisierung von Sedimenten der Saale
In: Geller, W., Punčochář, P., Bornhöft, D., Bouček, J., Feldmann, H., Guhr, H., Mohaupt, V., Simon, M., Smrtˇák, J., Spoustová, J., Uhlmann, O., (Hrsg.)
Gewässerschutz im Einzugsgebiet der Elbe. 8. Magdeburger Gewässerschutzseminar, Oktober 1998, Karlsbad (Tschechien)
B.G. Teubner, Stuttgart, Leipzig, S. 151 - 152
full text (url)
Grimme, L.H., Altenburger, R., Backhaus, T., Bödeker, W., Faust, M., Scholze, M., (1998):
Vorhersagbarkeit und Beurteilung der aquatischen Toxizität von Stoffgemischen: Multiple Kombinationen von unähnlich wirkenden Substanzen in niedrigen Konzentrationen
UFZ-Bericht 25/1998
UFZ Leipzig-Halle GmbH, Leipzig, 319 S.
full text (pdf)
Kortenkamp, A., Altenburger, R., (1998):
Synergisms with mixtures of xenoestrogens: A reevaluation using the method of isoboles
Sci. Total Environ. 221 (1), 59 - 73
full text (url)

1997 (5)

Altenburger, R., Ensenbach, U., Jung, K., Knops, M., Popp, P., Segner, H., Weiß, H., Schüürmann, G., (1997):
Ecotoxicity identification for the hazard characterization of groundwater contamination: a fingerprint approach for a contaminated site at Bitterfeld
In: Alef, K., Brandt, J., Fiedler, H., Hauthal, W., Hutzinger, O., Mackay, D., Matthies, M., Morgan, K., Newland, L., Robitaille, H., Schlummer, M., Schüürmann, G., Voigt, K., (eds.)
Information and Communication in Environmental and Health Issues. ECO-INFORMA '97, 6.-9.10.1997, Neuherberg
Eco-Informa Vol. 12
Eco-Informa Press, Bayreuth, p. 452 - 457
Altenburger, R., Ensenbach, U., Jung, K., Knops, M., Segner, H., (1997):
Ökotoxikologische Untersuchungen an Grundwasserproben
In: Weiß, H., Teutsch, G., Daus, B., (Hrsg.)
Sanierungsforschung in regional kontaminierten Aquiferen (SAFIRA): Bericht zur Machbarkeitsstudie für den Modellstandort Bitterfeld
UFZ-Bericht 27/1997
UFZ Leipzig-Halle GmbH, Leipzig, S. 94 - 98
full text (pdf)
Altenburger, R., Schüürmann, G., (1997):
Instrumentarien zur Bewertung möglicher Kombinationswirkungen von Schadstoffen auf die menschliche Gesundheit
Integrierte Bewertung radiologischer und chemisch-toxischer Kontaminanten: Workshop am 24.11.1997
Sächsisches Staatsministerium für Umwelt und Landesentwicklung, Dresden, p. 27 - 35
Backhaus, T., Froehner, K., Altenburger, R., Grimme, L.H., (1997):
Toxicity testing with Vibrio fischeri: A comparison between the long term (24 h) and the short term (30 min) bioassay
Chemosphere 35 (12), 2925 - 2938
full text (url)
Leibfritz, D., Altenburger, R., (1997):
Cell suspensions
In: Grant, D.M., Harris, R.K., (eds.)
Encyclopedia of nuclear magnetic resonance. Vol. 2
Wiley, New York, p. 1197 - 1209