Publication Details |
| Category | Text Publication |
| Reference Category | Journals |
| DOI | 10.2307/3455030 |
| Title (Primary) | Helicobacter pylori prevalences and risk factors among school beginners in a German urban center and its rural county |
| Author | Herbarth, O.; Krumbiegel, P.; Fritz, G.J.; Richter, M.; Schlink, U.
; Müller, D.M.; Richter, T. |
| Source Titel | Environmental Health Perspectives |
| Year | 2001 |
| Department | EXPOEPID |
| Volume | 109 |
| Issue | 6 |
| Page From | 573 |
| Page To | 577 |
| Language | englisch |
| Abstract | In 1998, the Helicobacter pylori [<sup>13</sup> C]urea breath test was offered to all school beginners (birth cohort 1991/1992) in the city of Leipzig and in Leipzig County, Germany, to determine the colonization prevalence and potential transmission pathways of the bacterium. A total of 3,347 school beginners participated in the test, and 2,888 parents completed the detailed, self-administered questionnaire. The H. pylori prevalence was 6.5% [95% confidence interval (CI), 5.3-7.6] in the city and 5.7% (CI, 4.2-7.0) in the county. Using cluster analysis (WARD's method, Euclidean distances), we identified different sets of variables (confirmed by multivariate logistic regression analyses [odds ratios (ORs)] that are significantly associated with H. pylori positivity. Among city children, the risk is significantly increased with contact to a pet hamster (OR = 2.4; 95% CI, 1.2-4.7; p < 0.015) and travels to Asian countries (OR = 3.7; 95% CI, 1.6-8.7; p < 0.002). Among county children, H. pylori positivity increased significantly with drinking of water from nonmunicipal sources (OR = 16.4; 95% CI, 3.1-88.5; p < 0.001), more than 3 children living in a household (OR = 4.2; 95% CI, 1.2-14.6; p < 0.02), and contact with pet hamsters (OR = 2.4; 95% CI, 1.0-5.7; p < 0.04). These data suggest that, in a general population sample, indirect fecal-oral transmission and living conditions are important risk factors in the spread of H. pylori infection. However, clinical symptoms do not necessarily indicate H. pylori positivity. |
| Persistent UFZ Identifier | https://www.ufz.de/index.php?en=20939&ufzPublicationIdentifier=6414 |
| Herbarth, O., Krumbiegel, P., Fritz, G.J., Richter, M., Schlink, U., Müller, D.M., Richter, T. (2001): Helicobacter pylori prevalences and risk factors among school beginners in a German urban center and its rural county Environ. Health Perspect. 109 (6), 573 - 577 10.2307/3455030 |
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