Publication Details

Category Text Publication
Reference Category Book chapters
Title (Primary) Does virulence decline by time in wild boar populations infected by Classical Swine Fever virus (CSFV)?
Title (Secondary) Society for Veterinary Epidemiology and Preventive Medicine: Proceedings of a meeting held in Leipzig, Germany, 23rd-25th March 2011
Author Lange, M.; Kramer-Schadt, S.; Thulke, H.-H. ORCID logo
Publisher Fourichon, C.; Pfeiffer, D.U.
Year 2011
Department OESA
Page From 154
Page To 167
Language englisch
Abstract Classical Swine Fever (CSF) is an endemic viral disease in European wild boar populations causing high economic impact to the pig farming industry. Virulence is a crucial factor determining persistence in local wild boar populations. We considered shift in virulence on the time scale of recent outbreaks using an individual-based spatially-explicit model which represents knowledge on wild boar ecology and CSF virus epidemiology. Two alternative scenarios were supposed as reasonable mechanisms that shift virulence pattern: 1) evolution of pathogen's virulence and 2) selection for host resistance. With both processes we found a possible short term shift to lower virulence. Pathogen evolution, however, resulted in faster decline down to a threshold level, while host selection resulted in slower but continuous decline of virulence. Both mechanisms promoted disease persistence.
Persistent UFZ Identifier https://www.ufz.de/index.php?en=20939&ufzPublicationIdentifier=11017
Lange, M., Kramer-Schadt, S., Thulke, H.-H. (2011):
Does virulence decline by time in wild boar populations infected by Classical Swine Fever virus (CSFV)?
In: Fourichon, C., Pfeiffer, D.U. (eds.)
Society for Veterinary Epidemiology and Preventive Medicine: Proceedings of a meeting held in Leipzig, Germany, 23rd-25th March 2011
Society for Veterinary Epidemiology and Preventive Medicine, p. 154 - 167