2024 (5)

• Aldehoff, A.S., Karkossa, I., Goerdeler, C., Krieg, L., Schor, J., Engelmann, B., Wabitsch, M., Landgraf, K., Hackermüller, J., Körner, A., Rolle-Kampczyk, U., Schubert, K., von Bergen, M. (2024):
  Unveiling the dynamics of acetylation and phosphorylation in SGBS and 3T3-L1 adipogenesis
  iScience 27 (6), art. 109711 10.1016/j.isci.2024.109711
• Monikh, F.A., Lehtonen, Š., Kekäläinen, J., Karkossa, I., Auriola, S., Schubert, K., Zanut, A., Peltonen, S., Niskanen, J., Bandekar, M., von Bergen, M., Leskinen, J.T.T., Koistinen, A., Bogialli, S., Guo, Z., Kukkonen, J.V.K., Chen, C., Lynch, I. (2024):
  Biotransformation of nanoplastics in human plasma and their permeation through a model in vitro blood-brain barrier: An in-depth quantitative analysis
  Nano Today 59 , art. 102466 10.1016/j.nantod.2024.102466
• Patt, M., Karkossa, I., Krieg, L., Massier, L., Makki, K., Tabei, S., Karlas, T., Dietrich, A., Gericke, M., Stumvoll, M., Blüher, M., von Bergen, M., Schubert, K., Kovacs, P., Chakaroun, R.M. (2024):
  FGF21 and its underlying adipose tissue-liver axis inform cardiometabolic burden and improvement in obesity after metabolic surgery
  EBioMedicine 110 , art. 105458 10.1101/2024.05.31.24307065
• Radushev, V., Karkossa, I., Berg, J., von Bergen, M., Engelmann, B., Rolle-Kampczyk, U.E., Blüher, M., Wagner, U., Schubert, K., Rossol, M. (2024):
  Dysregulated cytokine and oxidative response in hyper-glycolytic monocytes in obesity
  Front. Immunol. 15 , art. 1416543 10.3389/fimmu.2024.1416543
• Raps, S., Bahr, L., Karkossa, I., Rossol, M., von Bergen, M., Schubert, K. (2024):
  Triclosan and its alternatives, especially chlorhexidine, modulate macrophage immune response with distinct modes of action
  Sci. Total Environ. 941 , art. 169650 10.1016/j.scitotenv.2023.169650

2023 (11)

• Aldehoff, A.S., Karkossa, I., Engelmann, B., Rolle-Kampczyk, U., von Bergen, M., Schubert, K. (2023):
  Exploring the regulatory effects of lysine acetylation and phosphorylation in adipocyte differentiation and their exposure to emerging plastic additives
  Toxicol. Lett. 384 (Suppl. 1), S133 - S133 10.1016/S0378-4274(23)00578-7
• Bifari, F., Dolci, S., Mannino, L., Campanelli, A., Bottani, E., Karkossa, I., Setten, E., Gianoli, S., Di Chio, M., Ciarpella, F., Busetto, G., Pezzotta, A., Castagna, A., Pruonto, G., Binaschi, L., Amenta, A., Scupoli, M., Cavallini, C., Boschi, F., Doherty, A., Malpeli, G., Rossi, E., Martinelli, N., Ferretti, S., Malik, Z., Sandri, M., Pistocchi, A., Schubert, K., Endrizzi, M., Bossolasco, P., Fumagalli, G., Locati, M., Decimo, I. (2023):
  Adoptive transfer of tumor-educated macrophages promote neural tissue regeneration and motor recovery following severe spinal cord injury
  Cytotherapy 25 (6, Suppl.), E8 - E9 10.1016/S1465-3249(23)00711-9
• Gurbuz, B., Guldiken, N., Reuken, P., Fu, L., Remih, K., Preisinger, C., Brůha, R., Leníček, M., Petrtýl, J., Reissing, J., Aly, M., Fromme, M., Zhou, B., Karkossa, I., Schubert, K., von Bergen, M., Stallmach, A., Bruns, T., Strnad, P. (2023):
  Biomarkers of hepatocellular synthesis in patients with decompensated cirrhosis
  Hepatol. Int. 17 (3), 698 - 708 10.1007/s12072-022-10473-x
• Höper, T., Karkossa, I., Dumit, V.I., von Bergen, M., Schubert, K., Haase, A. (2023):
  A comparative proteomics analysis of four contact allergens in THP-1 cells shows distinct alterations in key metabolic pathways
  Toxicol. Appl. Pharmacol. 475 , art. 116650 10.1016/j.taap.2023.116650
• Karkossa, I., Fürst, S., Großkopf, H., von Bergen, M., Schubert, K. (2023):
  Oxidation is an underappreciated post-translational modification in the regulation of immune responses associated with changes in phosphorylation
  Front. Immunol. 14 , art. 1244431 10.3389/fimmu.2023.1244431
• Lipaeva, P., Karkossa, I., Bedulina, D., Schubert, K., Luckenbach, T. (2023):
  Cold-adapted amphipod species upon heat stress: Proteomic responses and their correlation with transcriptomic responses
  Comp. Biochem. Physiol. D-Genomics Proteomics 45 , art. 101048 10.1016/j.cbd.2022.101048
• Remih, K., Hufnagel, F., Durkalski-Mauldin, V., Lee, W.M., Su, C., Rule, J., Krieg, L., Karkossa, I., Schubert, K., von Bergen, M., Fontana, R., Strnad, P. (2023):
  Serum proteomics in American adults with acute liver failure
  J. Hepatol. 78 (Suppl. 1), S136 - S138 10.1016/S0168-8278(23)00638-4
• Remih, K., Hufnagel, F.-M., Durkalski-Mauldin, V., Lee, W., Su, Z., Rule, J., Krieg, L., Karkossa, I., Schubert, K., von Bergen, M., Fontana, R., Strnad, P. (2023):
  Serum proteomics in adults with Acute Liver Failure
  Z. Gastroent. 61 (08), e460 - e461 10.1055/s-0043-1771831
• Schubert, K., Karkossa, I. (2023):
  Effects of high molecular weight phthalates on LPS-stimulated THP-1 macrophages - redoxome
  PRoteomics IDEntifications Database (PRIDE) 10.6019/PXD043139
• Schubert, K., Karkossa, I. (2023):
  Effects of high molecular weight phthalates on LPS-stimulated THP-1 macrophages - proteome
  PRoteomics IDEntifications Database (PRIDE) 10.6019/PXD043025
• Schubert, K., Karkossa, I. (2023):
  Effects of high molecular weight phthalates on LPS-stimulated THP-1 macrophages - phosphoproteome
  PRoteomics IDEntifications Database (PRIDE) 10.6019/PXD042912

2022 (5)

• Krieg, L., Didt, K., Karkossa, I., Bernhart, S.H., Kehr, S., Subramanian, N., Lindhorst, A., Schaudinn, A., Tabei, S., Keller, M., Stumvoll, M., Dietrich, A., von Bergen, M., Stadler, P.F., Laurencikiene, J., Krüger, M., Blüher, M., Gericke, M., Schubert, K., Kovacs, P., Chakaroun, R., Massier, L. (2022):
  Multiomics reveal unique signatures of human epiploic adipose tissue related to systemic insulin resistance
  Gut 71 (11), 2179 - 2193 10.1136/gutjnl-2021-324603
• Lentz, L.S., Stutz, A.J., Meyer, N., Schubert, K., Karkossa, I., von Bergen, M., Zenclussen, A.C., Schumacher, A. (2022):
  Human chorionic gonadotropin promotes murine Treg cells and restricts pregnancy-harmful proinflammatory Th17 responses
  Front. Immunol. 13 , art. 989247 10.3389/fimmu.2022.989247
• Murthy, S., Karkossa, I., Schmidt, C., Hoffmann, A., Hagemann, T., Rothe, K., Seifert, O., Anderegg, U., von Bergen, M., Schubert, K., Rossol, M. (2022):
  Danger signal extracellular calcium initiates differentiation of monocytes into SPP1/osteopontin-producing macrophages
  Cell Death Dis. 13 , art. 53 10.1038/s41419-022-04507-3
• Schaffert, A., Karkossa, I., Ueberham, E., Schlichting, R., Walter, K., Arnold, J., Blüher, M., Heiker, J.T., Lehmann, J., Wabitsch, M., Escher, B.I., von Bergen, M., Schubert, K. (2022):
  Di-(2-ethylhexyl) phthalate substitutes accelerate human adipogenesis through PPARγ activation and cause oxidative stress and impaired metabolic homeostasis in mature adipocytes
  Environ. Int. 164 , art. 107279 10.1016/j.envint.2022.107279
• Schubert, K., Karkossa, I. (2022):
  Proteomic characterization of calcium macrophages
  PRoteomics IDEntifications Database (PRIDE) 10.6019/PXD026888

2021 (11)

• Großkopf, H., Walter, K., Karkossa, I., von Bergen, M., Schubert, K. (2021):
  Non-genomic AhR-signaling modulates the immune response in endotoxin-activated macrophages after activation by the environmental stressor BaP
  Front. Immunol. 12 , art. 620270 10.3389/fimmu.2021.620270
• Karkossa, I., Bannuscher, A., Hellack, B., Wohlleben, W., Laloy, J., Stan, M.S., Dinischiotu, A., Wiemann, M., Luch, A., Haase, A., von Bergen, M., Schubert, K. (2021):
  Nanomaterials induce different levels of oxidative stress, depending on the used model system: Comparison of in vitro and in vivo effects
  Sci. Total Environ. 801 , art. 149538 10.1016/j.scitotenv.2021.149538
• Karkossa, I., Bannuscher, A., Hellack, B., Wohlleben, W., Laloy, J., Stan, M.S., Dinischiotu, A., Wiemann, M., Luch, A., Haase, A., von Bergen, M., Schubert, K. (2021):
  Omics reveal different oxidative stress levels induced by nanomaterials in vitro and in vivo
  Toxicol. Lett. 350 (Suppl.), S125 10.1016/S0378-4274(21)00541-5
• Monikh, F.A., Chupani, L., Karkossa, I., Gardian, Z., Arenas-Logo, D., von Bergen, M., Schubert, K., Piackova, V., Zuskova, E., Jiskoot, W., Vijver, M.G., Peijnenburg, W.J.G.M. (2021):
  An environmental ecocorona influences the formation and evolution of the biological corona on the surface of single-walled carbon nanotubes
  NanoImpact 22 , art. 100315 10.1016/j.impact.2021.100315
• Schaffert, A., Arnold, J., Karkossa, I., Blüher, M., von Bergen, M., Schubert, K. (2021):
  The emerging plasticizer alternative DINCH and its metabolite MINCH induce oxidative stress and enhance inflammatory responses in human THP-1 macrophages
  Cells 10 (9), art. 2367 10.3390/cells10092367
• Schaffert, A., Krieg, L., Weiner, J., Schlichting, R., Ueberham, E., Karkossa, I., Bauer, M., Landgraf, K., Junge, K.M., Wabitsch, M., Lehmann, J., Escher, B.I., Zenclussen, A.C., Körner, A., Blüher, M., Heiker, J.T., von Bergen, M., Schubert, K. (2021):
  Alternatives for the worse: Molecular insights into adverse effects of bisphenol a and substitutes during human adipocyte differentiation
  Environ. Int. 156 , art. 106730 10.1016/j.envint.2021.106730
• Schaffert, A., Krieg, L., Weinert, J., Schlichting, R., Ueberham, E., Karkossa, I., Bauer, M., Junge, K., Wabitsch, M., Lehmann, J., Escher, B.I., Zenclussen, A.C., Körner, A., Blüher, M., Heiker, J.T., von Bergen, M., Schubert, K. (2021):
  Emerging substitutes of BPA cause inflammation-like state and impaired insulin sensitivity in differentiating human adipocytes
  Toxicol. Lett. 350 (Suppl.), S130 10.1016/S0378-4274(21)00552-X
• Schubert, K., Karkossa, I., Schor, J., Engelmann, B., Steinheuer, L.M., Bruns, T., Rolle-Kampczyk, U., Hackermüller, J., von Bergen, M. (2021):
  A multi-omics analysis of mucosal-associated-invariant T cells reveals key drivers of distinct modes of activation
  Front. Immunol. 12 , art. 616967 10.3389/fimmu.2021.616967
• Streidl, T., Karkossa, I., Segura Muñoz, R.R., Eberl, C., Zaufel, A., Plagge, J., Schmaltz, R., Schubert, K., Basic, M., Schneider, K.M., Afify, M., Trautwein, C., Tolba, R., Stecher, B., Doden, H.L., Ridlon, J.M., Ecker, J., Moustafa, T., von Bergen, M., Ramer-Tait, A.E., Clavel, T. (2021):
  The gut bacterium Extibacter muris produces secondary bile acids and influences liver physiology in gnotobiotic mice
  Gut Microbes 13 (1), 1 - 21 10.1080/19490976.2020.1854008
• Walter, K., Grosskopf, H., Karkossa, I., von Bergen, M., Schubert, K. (2021):
  Proteomic characterization of the cellular effects of AhR activation by microbial tryptophan catabolites in endotoxin-activated human macrophages
  Int. J. Environ. Res. Public Health 18 (19), 10336 10.3390/ijerph181910336
• Wang, Z., Karkossa, I., Großkopf, H., Canzler, S., Rolle-Kampczyk, U., Hackermüller, J., von Bergen, M., Schubert, K. (2021):
  Quantitative proteomics reveal mechanistic insights into direct and indirect drug-induced thyroid toxicity in rats
  Toxicol. Lett. 350 (Suppl.), S129 10.1016/S0378-4274(21)00550-6

2020 (5)

• Bannuscher, A., Karkossa, I., Buhs, S., Nollau, P., Kettler, K., Balas, M., Dinischiotu, A., Hellack, B., Wiemann, M., Luch, A., von Bergen, M., Haase, A., Schubert, K. (2020):
  A multi-omics approach reveals mechanisms of nanomaterial toxicity and structure–activity relationships in alveolar macrophages
  Nanotoxicology 14 (2), 181 - 195 10.1080/17435390.2019.1684592
• Hsu, M.-J., Karkossa, I., Schäfer, I., Christ, M., Kühne, H., Schubert, K., Rolle-Kampczyk, U.E., Kalkhof, S., Nickel, S., Seibel, P., von Bergen, M., Christ, B. (2020):
  Mitochondrial transfer by human mesenchymal stromal cells ameliorates hepatocyte lipid load in a mouse model of NASH
  Biomedicines 8 (9), art. 350 10.3390/biomedicines8090350
• Karkossa, I., Raps, S., von Bergen, M., Schubert, K. (2020):
  Systematic review of multi-omics approaches to investigate toxicological effects in macrophages
  Int. J. Mol. Sci. 21 (24), art. 9371 10.3390/ijms21249371
• Leppert, B., Strunz, S., Seiwert, B., Schlittenbauer, L., Schlichting, R., Pfeifer, C., Röder, S., Bauer, M., Borte, M., Stangl, G.I., Schöneberg, T., Schulz, A., Karkossa, I., Rolle-Kampczyk, U.E., Thürmann, L., von Bergen, M., Escher, B.I., Junge, K.M., Reemtsma, T., Lehmann, I., Polte, T. (2020):
  Maternal paraben exposure triggers childhood overweight development
  Nat. Commun. 11 , art. 561 10.1038/s41467-019-14202-1
• Wang, Z., Karkossa, I., Großkopf, H., Rolle-Kampczyk, U., Hackermüller, J., von Bergen, M., Schubert, K. (2020):
  Comparison of quantitation methods in proteomics to define relevant toxicological information on AhR activation of HepG2 cells by BaP
  Toxicology 448 , art. 152652 10.1016/j.tox.2020.152652

2019 (4)

• Karkossa, I., Bannuscher, A., Hellack, B., Bahl, A., Buhs, S., Nollau, P., Luch, A., Schubert, K., von Bergen, M., Haase, A. (2019):
  An in-depth multi-omics analysis in RLE-6TN rat alveolar epithelial cells allows for nanomaterial categorization
  Part. Fibre Toxicol. 16 (1), art. 38 10.1186/s12989-019-0321-5
• Kratochvil, I., Bannuscher, A., Hellack, B., von Bergen, M., Haase, A., Schubert, K. (2019):
  Nanomaterials affect oxidative phosphorylation and phagocytosis in alveolar macrophages
  Eur. J. Immunol. 49 (Suppl. 1), 232 10.1002/eji.201970300
• Kratochvil, I., Hofmann, T., Rother, S., Schlichting, R., Moretti, R., Scharnweber, D., Hintze, V., Escher, B.I., Meiler, J., Kalkhof, S., von Bergen, M. (2019):
  Mono(2‐ethylhexyl) phthalate (MEHP) and mono(2‐ethyl‐5‐oxohexyl) phthalate (MEOHP) but not di(2‐ethylhexyl) phthalate (DEHP) bind productively to the peroxisome proliferator‐activated receptor γ
  Rapid Commun. Mass Spectrom. 33 (S1), 75 - 85 10.1002/rcm.8258
• Schubert, K., Schor, J., Kratochvil, I., Hackermüller, J., von Bergen, M. (2019):
  Multi-omics profiling of MAIT cells reveals specific patterns of antigen-dependent and -independent activation
  Eur. J. Immunol. 49 (Suppl. 1), 141 10.1002/eji.201970300

2018 (1)

• May, J.C., Jurneczko, E., Stow, S.M., Kratochvil, I., Kalkhof, S., McLean, J.A. (2018):
  Conformational landscapes of ubiquitin, cytochrome c, and myoglobin: Uniform field ion mobility measurements in helium and nitrogen drift gas
  Int. J. Mass Spectrom. 427 , 79 - 90 10.1016/j.ijms.2017.09.014