Dr. Isabel Karkossa

(Née Kratochvil)

Postdoc in der Functional Genomics Gruppe

Kontakt

Department Molekulare Systembiologie (MOLSYB)
Helmholtz-Zentrum für Umweltforschung - UFZ
Permoser Str. 15
04318 Leipzig

Tel: +49 341 235 1354
isabel.karkossa@ufz.de
ResearchGate
@IKarkossa

IK

Forschungsschwerpunkte

  • Systembiologische Analyse der modes of action von Schadstoffen in Immunzellen
  • Proteomics


Lebenslauf

2019 - heute

Postdoc
Helmholtz-Zentrum für Umweltforschung, Leipzig

2016 - 2019

Doktorarbeit
Helmholtz-Zentrum für Umweltforschung, Leipzig
Proteomics zur Bewertung von Nanomaterialien entsprechend ihrer Wirkung

2015

Forschungsaufenthalt
Vanderbilt University, Nashville, TN, USA
Untersuchung von Biomolekülen mittels Ionenmobilitäts-Massenspektrometrie

2014 - 2016

Masterstudium Biochemie
Universität Leipzig, Schwerpunkt Biomedizin
Untersuchung von Interaktionen des PPARγ mit Phthalaten mittels HDX-MS

2011 - 2014

Bachelorstudium Biochemie
Martin-Luther-Universität Halle-Wittenberg
Evaluierung eines MS/MS-spaltbaren Crosslinkers zur 3D-Strukturvorhersage von Proteinen


Publikationen

2022 (3)

2021 (12)

2020 (5)

2019 (4)

2018 (1)

  • Ihling, C., Falvo, F., Kratochvil, I., Sinz, A., & Schäfer, M. (2015). Dissociation behavior of a bifunctional tempo-active ester reagent for peptide structure analysis by free radical initiated peptide sequencing (FRIPS) mass spectrometry. J Mass Spectrom, 50(2), 396-406

Poster & Talks

Karkossa, I., Bannuscher, A., Hellack, B., Wohlleben, W., Laloy, J., Stan, M.S., Dinischiotu, A., Wiemann, M., Luch, L., Haase, A., von Bergen, M., Schubert, K. (2021). Omics reveal different oxidative stress levels induced by nanomaterials in vitro and in vivo. Poster presented at the Eurotox, virtual meeting.

Karkossa, I., Bannuscher, A., Hellack, B., Haase, A., Schubert, K., von Bergen, M. (2019). Weighted Gene Correlation Network Analysis of multi-omics data highlights effect-inducing properties and biomarker candidates: An application for nanomaterial grouping. Poster presented at the Young Scientists Fall Meeting of the German Society of Mass Spectrometry, Hünfeld, Germany.

Karkossa, I., Bannuscher, A., Hellack, B., von Bergen, M., Haase, A., Schubert, K. (2019). Nanomaterials affect oxidative phosphorylation and phagocytosis in alveolar macrophages. Poster presented at Joint Meeting of the German Society for Immunology and the Italian Society of Immunology, München, Germany.

Kratochvil, I., Bannuscher, A., Hellack, B., Haase A., Schubert, K., von Bergen, M. (2019). Multi-Omics to Develop Nanomaterial Grouping Strategies for Risk Assessment. Poster presented at Proteomic Forum, Potsdam, Germany.

Kratochvil, I., Bannuscher, A., Kettler, K., Haase A., von Bergen, M., Schubert, K. (2018). Weighted Gene Correlation Network Analysis to develop nanomaterial grouping strategies. Talk at 9th International Conference on Nanotoxicology, Neuss, Germany.

Kratochvil, I., Bannuscher, A., Kettler, K., Haase A., Schubert, K., von Bergen, M. (2018). Weighted Gene Correlation Network Analysis as Grouping Strategy for Nanomaterial Risk Assessment in Alveolar Macrophages. Poster presented at European Mass Spectrometry Conference, Saarbrücken, Germany.

Kratochvil, I., Bannuscher, A., Haase A., Schubert K., von Bergen, M. (2018). Weighted Gene Correlation Network Analysis as Grouping Strategy for Nanomaterial Risk Assessment. Poster presented at Research Festival, Leipzig, Germany.

Kratochvil, I., Hofmann, T., Schlichting R., Escher E., Kalkhof, S., von Bergen, M. (2017). MEHP and MEOHP but not DEHP bind and activate the peroxisome proliferator-activated receptor γ. Poster presented at meeting of German Society of Mass Spectrometry, Kiel, Germany.