Dr. Loreen Thürmann

Kontakt

Dr. Loreen Thürmann

Gastwissenschaftlerin

Department Umweltimmunologie
Helmholtz-Zentrum für Umweltforschung – UFZ
Permoserstr. 15
04318 Leipzig


Tel.: +49 341 235-1544
Fax: +49 341 235-1787

Dr. Loreen Thürmann
Foto: Sebastian Wiedling/UFZ

Research Interests

• Epigenetic perturbations related to environmental exposures
• Early DNA-methylations patterns and their relation to the development of allergic
  diseases


Curriculum vitae / Scientific career

08/2009

B.Sc. Biochemistry, University of Leipzig

11/2010 - 01/2011 

Internship at the Max Planck Institute of Molecular Cell Biology and Genetics (Dresden, Prof. Dr. Karla M. Neugebauer)

02/2011 - 01/2012

Research stay and study abroad semester at the University of Queensland, Brisbane/Australia (Institute for Molecular Bioscience, Prof. Dr. John Mattick)

03/2012

M.Sc. Biochemistry, University of Leipzig
Master thesis: “Characterization of the long non-coding RNA HAR1A“ (Prof. Dr. Friedemann Horn, Prof. Dr. John Mattick)

10/2012 - 10/2015

PhD student at the Helmholtz Centre for Environmental Research - UFZ
Department of Environmental Immunology (Dr. Irina Lehmann, Dr. Saskia Trump)
Doctoral study at the University of Heidelberg, Faculty of Biosciences (Prof. Dr. Roland Eils)
Thesis: “Prenatal environment-associated epigenetic perturbations and their link to adverse phenotype development in early childhood” (magna cum laude)
Defense in 11/2016

11/2015 - 12/2017

Research Fellow at the Helmholtz Centre for Environmental Research - UFZ
Department of Environmental Immunology (Dr. Irina Lehmann)

since 01/2018

Guest Scientist at the Department of Environmental Immunology

since 01/2018

Postdoc Scientist in Molecular Epidemiology at Berlin Institut of Health

Grants

03/2011 - 11/2011

German Academic Exchange Service (DAAD) grant for graduates


Publications

Inhalt:

2018 (2)
2017 (3)
2016 (4)

Weiterführende Recherchen können Sie in unserem Publikationsverzeichnis durchführen.

2018 (2)

  • Jahreis, S., Trump, S., Bauer, M., Bauer, T., Thürmann, L., Feltens, R., Wang, Q., Gu, L., Grützmann, K., Röder, S., Averbeck, M., Weichenhan, D., Plass, C., Sack, U., Borte, M., Dubourg, V., Schüürmann, G., Simon, J.C., von Bergen, M., Hackermüller, J., Eils, R., Lehmann, I., Polte, T., (2018):
    Maternal phthalate exposure promotes allergic airway inflammation over 2 generations through epigenetic modifications
    J. Allergy Clin. Immunol. 141 (2), 741 - 753
    Volltext (URL)
  • Thürmann, L., Grützmann, K., Klos, M., Bieg, M., Winter, M., Polte, T., Bauer, T., Schick, M., Bewerunge-Hudler, M., Roeder, S., Bauer, M., Wissenbach, D.K., Sack, U., Weichenhan, D., Mücke, O., Plass, C., Borte, M., von Bergen, M., Lehmann, I., Eils, R., Trump, S., (2018):
    Early-onset childhood atopic dermatitis is related to NLRP2 repression
    J. Allergy Clin. Immunol.
    Volltext (URL)
zum Inhalt

2017 (3)

  • Dewi, D.L., Mohapatra, S.R., Cabañes, S.B., Adam, I., Patterson, L.F.S., Berdel, B., Kahloon, M., Thürmann, L., Loth, S., Heilmann, K., Weichenhan, D., Mücke, O., Heiland, I., Wimberger, P., Kuhlmann, J.D., Kellner, K.-H., Schott, S., Plass, C., Platten, M., Gerhäuser, C., Trump, S., Opitz, C.A., (2017):
    Suppression of indoleamine-2,3-dioxygenase 1 expression by promoter hypermethylation in ER-positive breast cancer
    Oncoimmunology 6 (2), e1274477
    Volltext (URL)
  • Trump, S., Klos, M., Gu, L., Bauer, T., Ishaque, N., Thurmann, L., Bieg, M., Bauer, M., Gu, Z., Borte, M., Mallm, J.-P., Roder, S., Herrmann, C., Rippe, K., Lehmann, I., Eils, R., (2017):
    Asthma development in early childhood is associated with enhancer reprogramming
    Am. J. Respir. Crit. Care Med. 195 , A4910
    Volltext (URL)
  • Winter, M., Thürmann, L., Gu, Z., Schüürmann, G., Herberth, G., Hinz, D., von Bergen, M., Harms, H., Olek, S., Röder, S., Borte, M., Eils, R., Lehmann, I., Trump, S., (2017):
    The benzene metabolite 1,4-benzoquinone reduces regulatory T-cell function: A potential mechanism for tobacco smoke–associated atopic dermatitis
    J. Allergy Clin. Immunol. 140 (2), 603 - 605
    Volltext (URL)
zum Inhalt

2016 (4)

  • Bauer, M., Fink, B., Thürmann, L., Eszlinger, M., Herberth, G., Lehmann, I., (2016):
    Tobacco smoking differently influences cell types of the innate and adaptive immune system—indications from CpG site methylation
    Clin. Epigenetics 8 , art. 83
    Volltext (URL)
  • Bauer, T., Trump, S., Ishaque, N., Thürmann, L., Gu, L., Bauer, M., Bieg, M., Gu, Z., Weichenhan, D., Mallm, J.-P., Röder, S., Herberth, G., Takada, E., Mücke, O., Winter, M., Junge, K.M., Grützmann, K., Rolle-Kampczyk, U., Wang, Q., Lawerenz, C., Borte, M., Polte, T., Schlesner, M., Schanne, M., Wiemann, S., Geörg, C., Stunnenberg, H.G., Plass, C., Rippe, K., Mizuguchi, J., Herrmann, C., Eils, R., Lehmann, I., (2016):
    Environment-induced epigenetic reprogramming in genomic regulatory elements in smoking mothers and their children
    Mol. Syst. Biol. 12 (3), art. 861
    Volltext (URL)
  • Junge, K.M., Bauer, T., Geissler, S., Hirche, F., Thürmann, L., Bauer, M., Trump, S., Bieg, M., Weichenhan, D., Gu, L., Mallm, J.-P., Ishaque, N., Mücke, O., Röder, S., Herberth, G., Diez, U., Borte, M., Rippe, K., Plass, C., Hermann, C., Stangl, G.I., Eils, R., Lehmann, I., (2016):
    Increased vitamin D levels at birth and in early infancy increase offspring allergy risk—evidence for involvement of epigenetic mechanisms. Letter to the editor
    J. Allergy Clin. Immunol. 137 (2), 610 - 613
    Volltext (URL)
  • Trump, S., Bieg, M., Gu, Z., Thürmann, L., Bauer, T., Bauer, M., Ishaque, N., Röder, S., Gu, L., Herberth, G., Lawerenz, C., Borte, M., Schlesner, M., Plass, C., Diessl, N., Eszlinger, M., Mücke, O., Elvers, H.-D., Wissenbach, D.K., von Bergen, M., Herrmann, C., Weichenhan, D., Wright, R.J., Lehmann, I., Eils, R., (2016):
    Prenatal maternal stress and wheeze in children: novel insights into epigenetic regulation
    Sci. Rep. 6 , art. 28616
    Volltext (URL)
zum Inhalt