Prof. Dr. Rolf Altenburger

Prof. Dr. Rolf Altenburger

Adresse:
Permoserstr. 15
04318 Leipzig

Gebäude: 6.0
Raum: 317
Telefon: +49 341 235 1522

Dr. Rolf Altenburger

Curriculum Vitae

Rolf Altenburger is Head of the Department Bioanalytical Ecotoxicology since 2005. He holds a professorship at the RWTH Aachen University, Institute for Environmental Research. His professional activities comprise the Editorial Board of Environmental Pollution, Membership in advisory groups, e.g. on the German plant protection action plan or being speaker of the HGF programme topic Chemicals in the Environment (CITE).

Rolf Altenburger received his Doctor of Science from the University of Bremen. Previous to his appointment at the RWTH Aachen he held a venia legendi at the University of Bremen and the TU Bergakademie Freiberg. His professional training as a biologist included studies at the Universities of Marburg, Freiburg, and Bremen, Germany, and St.Andrews, Scotland. He obtained research fellowships to Shabat Alam Malaysia, Penang, Malaysa; Visaya State College of Agriculture, Leyte, The Philippines; Roswell Park Cancer Institute, Buffalo, NY, USA; and the National Research Centre for Environmental Toxicology (ENTOX), Brisbane, Australia.

Rolf Altenburger’s research interests focus on

  • Mixture toxicity assessment for complex environmental exposure;
  • Bioassays for toxicant identification at multiple contaminated sites;
  • Mode-of-action analysis for toxicants;
  • Pharmacokinetic-pharmacodynamic (PKPD) models to mechanistically describe concentration and time dependent toxicity.

Traditional chemicals risk assessment considers chemicals one by one while organisms in the environment typically are confronted with exposure to multiple substances. For more than a decade, we have been investigating mixture effects to improve environmental risk assessment. Milestones in our work comprise answers to the following questions: Can we establish bioassays that allow detection of combination effects? For several ecotoxicity assays from subcellular to community level we could successfully demonstrate this. Secondly, can we predict mixture toxicity based on the information about the components biological activities? For apical effects and an array of mixtures of environmental contaminants we could support the notion that extrapolative modelling is indeed possible. The more precise the prediction is needed, the more mechanism-based information is required. Currently, want to extend our knowledge in two directions: namely the understanding of mixture interactions at a molecular level (Exposome) and the combined effects under conditions of multiple stress.

Publikationen

2017 (11)

  • Altenburger, R., Gündel, U., Rotter, S., Vogs, C., Faust, M., Backhaus, T., (2017):
    Establishment of a concept for comparative risk assessment of plant protection products with special focus on the risks to the environment. Project No. (FKZ) 3712 67 406. Report No. (UBA-FB) 002256/ENG
    Texte Umweltbundesamt 47/2017
    Umweltbundesamt, Dessau-Roßlau, 215 pp.
    Volltext (URL)
  • Brack, W., Dulio, V., Ågerstrand, M., Allan, I., Altenburger, R., Brinkmann, M., Bunke, D., Burgess, R.M., Cousins, I., Escher, B.I., Hernández, F.J., Hewitt, L.M., Hilscherová, K., Hollender, J., Hollert, H., Kase, R., Klauer, B., Lindim, C., López Herráez, D., Miège, C., Munthe, J., O'Toole, S., Posthuma, L., Rüdel, H., Schäfer, R.B., Sengl, M., Smedes, F., van de Meent, D., van den Brink, P., van Gils, J., van Wezel, A.P., Dick Vethaak, A., Vermeirssen, E., von der Ohe, P.C., Vrana, B., (2017):
    Towards the review of the European Union Water Framework Directive: Recommendations for more efficient assessment and management of chemical contamination in European surface water resources
    Sci. Total Environ. 576 , 720 - 737
    Volltext (URL)
  • Diamond, J., Altenburger, R., Coors, A., Dyer, S., Focazio, M., Kidd, K., Koelmans, A.A., Leung, K.M.Y., Servos, M., Snape, J., Tolls, J., Zhang, X., (2017):
    Use of prospective and retrospective risk assessment methods that simplify chemical mixtures associated with treated domestic wastewater discharges
    Environ. Toxicol. Chem.
    Volltext (URL)
  • Escher, B.I., Hackermüller, J., Polte, T., Scholz, S., Aigner, A., Altenburger, R., Böhme, A., Bopp, S.K., Brack, W., Busch, W., Chadeau-Hyam, M., Covaci, A., Eisenträger, A., Galligan, J.J., Garcia-Reyero, N., Hartung, T., Hein, M., Herberth, G., Jahnke, A., Kleinjans, J., Klüver, N., Krauss, M., Lamoree, M., Lehmann, I., Luckenbach, T., Miller, G.W., Müller, A., Phillips, D.H., Reemtsma, T., Rolle-Kampczyk, U., Schüürmann, G., Schwikowski, B., Tan, Y.-M., Trump, S., Walter-Rohde, S., Wambaugh, J.F., (2017):
    From the exposome to mechanistic understanding of chemical-induced adverse effects
    Environ. Int. 99 , 97 - 106
    Volltext (URL)
  • Jakob, L., Bedulina, D.S., Axenov-Gribanov, D.V., Ginzburg, M., Shatilina, Z.M., Lubyaga, Y.A., Madyarova, E.V., Gurkov, A.N., Timofeyev, M.A., Portner, H.-O., Sartoris, F.J., Altenburger, R., Luckenbach, T., (2017):
    Uptake kinetics and subcellular compartmentalization explain lethal but not sublethal effects of cadmium in two closely related amphipod species
    Environ. Sci. Technol. 51 (12), 7208 - 7218
    Volltext (URL)
  • Kühnert, A., Vogs, C., Seiwert, B., Aulhorn, S., Altenburger, R., Hollert, H., Küster, E., Busch, W., (2017):
    Biotransformation in the zebrafish embryo – temporal gene transcription changes of cytochrome P450 enzymes and internal exposure dynamics of the AhR binding xenobiotic benz[a]anthracene
    Environ. Pollut. 230 , 1 - 11
    Volltext (URL)
  • Munthe, J., Brorström-Lundén, E., Rahmberg, M., Posthuma, L., Altenburger, R., Brack, W., Bunke, D., Engelen, G., Gawlik, B.M., van Gils, J., López Herráez, D., Rydberg, T., Slobodnik, J., van Wezel, A., (2017):
    An expanded conceptual framework for solution-focused management of chemical pollution in European waters
    Environmental Sciences Europe 29 , art. 13
    Volltext (URL)
  • Neale, P.A., Altenburger, R., Aït-Aïssa, S., Brion, F., Busch, W., De Aragão Umbuzeiro, G., Denison, M.S., Du Pasquier, D., Hilscherová, K., Hollert, H., Morales, D.A., Novák, J., Schlichting, R., Seiler, T.-B., Serra, H., Shao, Y., Tindall, A.J., Tollefsen, K.E., Williams, T.D., Escher, B.I., (2017):
    Development of a bioanalytical test battery for water quality monitoring: Fingerprinting identified micropollutants and their contribution to effects in surface water
    Water Res. 123 , 734 - 750
    Volltext (URL)
  • Neale, P.A., Munz, N.A., Aїt-Aїssa, S., Altenburger, R., Brion, F., Busch, W., Escher, B.I., Hilscherová, K., Kienle, C., Novák, J., Seiler, T.-B., Shao, Y., Stamm, C., Hollender, J., (2017):
    Integrating chemical analysis and bioanalysis to evaluate the contribution of wastewater effluent on the micropollutant burden in small streams
    Sci. Total Environ. 576 , 785 - 795
    Volltext (URL)
  • Schmidt, S., Altenburger, R., Kühnel, D., (2017):
    From the air to the water phase: implication for toxicity testing of combustion-derived particles
    Biomass Conversion and Biorefinery
    Volltext (URL)
  • Schüttler, A., Reiche, K., Altenburger, R., Busch, W., (2017):
    The transcriptome of the zebrafish embryo after chemical exposure: a meta-analysis
    Toxicol. Sci. 157 (2), 291 - 304
    Volltext (URL)

2016 (7)

  • Busch, W., Schmidt, S., Kühne, R., Schulze, T., Krauss, M., Altenburger, R., (2016):
    Micropollutants in European rivers: A mode of action survey to support the development of effect-based tools for water monitoring
    Environ. Toxicol. Chem. 35 (8), 1887 - 1899
    Volltext (URL)
  • Faria, M., Pavlichenko, V.V., Burkhardt-Medicke, K., Soares, A.M.V.M., Altenburger, R., Barata, C., Luckenbach, T., (2016):
    Corrigendum to "Use of a combined effect model approach for discriminating between ABCB1- and ABCC1-type efflux activities in native bivalve gill tissue" [Toxicol. Appl. Pharmacol. (2016) 56–67]
    Toxicol. Appl. Pharmacol. 303 , 110
    Volltext (URL)
  • Faria, M., Pavlichenko, V.V., Burkhardt-Medicke, K., Soares, A.M.V.M., Altenburger, R., Barata, C., Luckenbach, T., (2016):
    Use of a combined effect model approach for discriminating between ABCB1- and ABCC1-type efflux activities in native bivalve gill tissue
    Toxicol. Appl. Pharmacol. 297 , 56 - 67
    Volltext (URL)
  • Klüver, N., Vogs, C., Altenburger, R., Escher, B.I., Scholz, S., (2016):
    Development of a general baseline toxicity QSAR model for the fish embryo acute toxicity test
    Chemosphere 164 , 164 - 173
    Volltext (URL)
  • Rose, S., Altenburger, R., Sturm, A., (2016):
    Mixture toxicity effects of sea louse control agents in Daphnia magna
    Chemosphere 144 , 599 - 606
    Volltext (URL)
  • Schmidt, S., Busch, W., Altenburger, R., Küster, E., (2016):
    Mixture toxicity of water contaminants-effect analysis using the zebrafish embryo assay (Danio rerio)
    Chemosphere 152 , 503 - 512
    Volltext (URL)
  • Vogs, C., Altenburger, R., (2016):
    Time-dependent effects in algae for chemicals with different adverse outcome pathways: a novel approach
    Environ. Sci. Technol. 50 (14), 7770 - 7780
    Volltext (URL)

2015 (9)

  • Altenburger, R., Ait-Aissa, S., Antczak, P., Backhaus, T., Barceló, D., Seiler, T.-B., Brion, F., Busch, W., Chipman, K., López de Alda, M., De Aragão Umbuzeiro, G., Escher, B.I., Falciani, F., Faust, M., Focks, A., Hilscherova, K., Hollender, J., Hollert, H., Jäger, F., Jahnke, A., Kortenkamp, A., Krauss, M., Lemkine, G.F., Munthe, J., Neumann, S., Schymanski, E.L., Scrimshaw, M., Segner, H., Slobodnik, J., Smedes, F., Kughathas, S., Teodorovic, I., Tindall, A.J., Tollefsen, K.E., Walz, K.-H., Williams, T.D., van den Brink, P.J., van Gils, J., Vrana, B., Zhang, X., Brack, W., (2015):
    Future water quality monitoring — Adapting tools to deal with mixtures of pollutants in water resource management
    Sci. Total Environ. 512-513 , 540 - 551
    Volltext (URL)
  • Brack, W., Altenburger, R., Schüürmann, G., Krauss, M., López Herráez, D., van Gils, J., Slobodnik, J., Munthe, J., Gawlik, B.M., van Wezel, A., Schriks, M., Hollender, J., Tollefsen, K.E., Mekenyan, O., Dimitrov, S., Bunke, D., Cousins, I., Posthuma, L., van den Brink, P.J., López de Alda, M., Barceló, D., Faust, M., Kortenkamp, A., Scrimshaw, M., Ignatova, S.N., Engelen, G., Massmann, G., Lemkine, G., Teodorovic, I., Walz, K.-H., Dulio, V., Jonker, M.T.O., Jäger, F., Chipman, K., Falciani, F., Liska, I., Rooke, D., Zhang, X., Hollert, H., Vrana, B., Hilscherova, K., Kramer, K., Neumann, S., Hammerbacher, R., Backhaus, T., Mack, J., Segner, H., Escher, B., De Aragão Umbuzeiro, G., (2015):
    The SOLUTIONS project: challenges and responses for present and future emerging pollutants in land and water resources management
    Sci. Total Environ. 503-504 , 22 - 31
    Volltext (URL)
  • Fetter, E., Smetanová, S., Baldauf, L., Lidzba, A., Altenburger, R., Schüttler, A., Scholz, S., (2015):
    Identification and characterization of androgen-responsive genes in zebrafish embryos
    Environ. Sci. Technol. 49 (19), 11789 - 11798
    Volltext (URL)
  • Luckenbach, T., Küster, E., Busch, W., Scholz, S., Altenburger, R., (2015):
    What determines chemical uptake by the zebrafish embryo model?
    Toxicol. Lett. 238 (2, Suppl.), S54
    Volltext (URL)
  • Massei, R., Vogs, C., Renner, P., Altenburger, R., Scholz, S., (2015):
    Differential sensitivity in embryonic stages of the zebrafish (Danio rerio): The role of toxicokinetics for stage-specific susceptibility for azinphos-methyl lethal effects
    Aquat. Toxicol. 166 , 36 - 41
    Volltext (URL)
  • Riedl, J., Schreiber, R., Otto, M., Heilmeier, H., Altenburger, R., Schmitt-Jansen, M., (2015):
    Metabolic effect level index links multivariate metabolic fingerprints to ecotoxicological effect assessment
    Environ. Sci. Technol. 49 (13), 8096 - 8104
    Volltext (URL)
  • Rotter, S., Gunold, R., Mothes, S., Paschke, A., Brack, W., Altenburger, R., Schmitt-Jansen, M., (2015):
    Pollution-induced community tolerance to diagnose hazardous chemicals in multiple contaminated aquatic systems
    Environ. Sci. Technol. 49 (16), 10048 - 10056
    Volltext (URL)
  • Smetanová, S., Riedl, J., Zitzkat, D.P., Altenburger, R., Busch, W., (2015):
    High-throughput concentration–response analysis for omics datasets
    Environ. Toxicol. Chem. 34 (9), 2167 - 2180
    Volltext (URL)
  • Vogs, C., Kühnert, A., Hug, C., Küster, E., Altenburger, R., (2015):
    A toxicokinetic study of specifically acting and reactive organic chemicals for the prediction of internal effect concentrations in Scenedesmus vacuolatus
    Environ. Toxicol. Chem. 34 (1), 100 - 111
    Volltext (URL)

2014 (5)

  • Altenburger, R., Arrhenius, A., Backhaus, T., Coors, A., Faust, M., Zitzkat, D.P., (2014):
    Ecotoxicological combined effects from chemical mixtures. Part 1: Relevance and adequate consideration in environmental risk assessment of plant protection products and biocides
    Texte Umweltbundesamt 92/2013
    Umweltbundesamt, Dessau-Roßlau, 203 pp.
    Volltext (URL)
  • Campos, B., Altenburger, R., Gómez, C., Lacorte, S., Piña, B., Barata, C., Luckenbach, T., (2014):
    First evidence for toxic defense based on the multixenobiotic resistance (MXR) mechanism in Daphnia magna
    Aquat. Toxicol. 148 , 139 - 151
    Volltext (URL)
  • Escher, B.I., Allinson, M., Altenburger, R., Bain, P.A., Balaguer, P., Busch, W., Crago, J., Denslow, N.D., Dopp, E., Hilscherova, K., Humpage, A.R., Kumar, A., Grimaldi, M., Jayasinghe, B.S., Jarosova, B., Jia, A., Makarov, S., Maruya, K.A., Medvedev, A., Mehinto, A.C., Mendez, J.E., Poulsen, A., Prochazka, E., Richard, J., Schifferli, A., Schlenk, D., Scholz, S., Shiraishi, F., Snyder, S., Su, G., Tang, J.Y.M., van der Burg, B., van der Linden, S.C., Werner, I., Westerheide, S.D., Wong, C.K.C., Yang, M., Yeung, B.H.Y., Zhang, X., Leusch, F.D.L., (2014):
    Benchmarking organic micropollutants in wastewater, recycled water and drinking water with in vitro bioassays
    Environ. Sci. Technol. 48 (3), 1940 - 1956
    Volltext (URL)
  • Faust, M., Vogs, C., Rotter, S., Wöltjen, J., Höllrigl-Rosta, A., Backhaus, T., Altenburger, R., (2014):
    Comparative assessment of plant protection products: how many cases will regulatory authorities have to answer?
    Environmental Sciences Europe 26 , art. 11
    Volltext (URL)
  • Pannier, A., Soltmann, U., Soltmann, B., Altenburger, R., Schmitt-Jansen, M., (2014):
    Alginate/silica hybrid materials for immobilization of green microalgae Chlorella vulgaris for cell-based sensor arrays
    J. Mat. Chem. B 45 (2), 7896 - 7909
    Volltext (URL)

2013 (7)

  • Altenburger, R., Backhaus, T., Boedeker, W., Faust, M., Scholze, M., (2013):
    Simplifying complexity : mixture toxicity assessment in the last 20 years
    Environ. Toxicol. Chem. 32 (8), 1685 - 1687
    Volltext (URL)
  • Backhaus, T., Altenburger, R., Faust, M., Frein, D., Frische, T., Johansson, P., Kehrer, A., Porsbring, T., (2013):
    Proposal for environmental mixture risk assessment in the context of the biocidal product authorization in the EU
    Environmental Sciences Europe 25 , art. 4
    Volltext (URL)
  • Escher, B.I., van Daele, C., Dutt, M., Tang, J.Y.M., Altenburger, R., (2013):
    Most oxidative stress response in water samples comes from unknown chemicals: the need for effect-based water quality trigger values
    Environ. Sci. Technol. 47 (13), 7002 - 7011
    Volltext (URL)
  • Kühnert, A., Vogs, C., Altenburger, R., Küster, E., (2013):
    The internal concentration of organic substances in fish embryos - a toxicokinetic approach
    Environ. Toxicol. Chem. 32 (8), 1819 - 1827
    Volltext (URL)
  • Riedl, J., Rotter, S., Faetsch, S., Schmitt-Jansen, M., Altenburger, R., (2013):
    Proposal for applying a component-based mixture approach for ecotoxicological assessment of fracturing fluids
    Environ. Earth Sci. 70 (8), 3907 - 3920
    Volltext (URL)
  • Rotter, S., Heilmeier, H., Altenburger, R., Schmitt-Jansen, M., (2013):
    Multiple stressors in periphyton – comparison of observed and predicted tolerance responses to high ionic loads and herbicide exposure
    J. Appl. Ecol. 50 (6), 1459 - 1468
    Volltext (URL)
  • Vogs, C., Bandow, N., Altenburger, R., (2013):
    Effect propagation in a toxicokinetic/toxicodynamic model explains delayed effects on the growth of unicellular green algae Scenedesmus vacuolatus
    Environ. Toxicol. Chem. 32 (5), 1161 - 1172
    Volltext (URL)

2012 (5)

  • Altenburger, R., Scholz, S., Schmitt-Jansen, M., Busch, W., Escher, B.I., (2012):
    Mixture toxicity revisited from a toxicogenomic perspective
    Environ. Sci. Technol. 46 (5), 2508 - 2522
    Volltext (URL)
  • Frimmel, F.H., Ewers, U., Schmitt-Jansen, M., Gordalla, B., Altenburger, R., (2012):
    Toxikologische Bewertung von Fracking-Fluiden
    Wasser und Abfall 14 (6), 22 - 29
  • Gündel, U., Kalkhof, S., Zitzkat, D.P., von Bergen, M., Altenburger, R., Küster, E., (2012):
    Concentration-response concept in ecotoxicoproteomics: effects of different phenanthrene concentrations to the zebrafish (Danio rerio) embryo proteome
    Ecotox. Environ. Safe. 76 (1), 11 - 22
    Volltext (URL)
  • Riedl, J., Kluender, C., Sans-Piché, F., Heilmeier, H., Altenburger, R., Schmitt-Jansen, M., (2012):
    Spatial and temporal variation in metabolic fingerprints of field-growing Myriophyllum spicatum
    Aquat. Bot. 102 , 34 - 43
    Volltext (URL)
  • van Dam, J.W., Negri, A.P., Mueller, J.F., Altenburger, R., Uthicke, S., (2012):
    Additive pressures of elevated sea surface temperatures and herbicides on symbiont-bearing foraminifera
    PLoS One 7 (3), e33900
    Volltext (URL)

2011 (7)

  • Altenburger, R., (2011):
    Understanding combined effects for metal co-exposure in ecotoxicology
    In: Sigel, A., Sigel, H., Sigel, R.K.O., (eds.)
    Metal ions in toxicology: effects, interactions, interdependencies
    Metal Ions in Life Sciences 8
    Royal Society of Chemistry (RSC), Cambridge, p. 1 - 26
    Volltext (URL)
  • Kortenkamp, A., Altenburger, R., (2011):
    Toxicity from combined exposure to chemicals
    In: van Gestelt, C.A.M., Jonker, M.J., Kammenga, J.E., (eds.)
    Mixture toxicity: linking approaches from ecotoxicology and human toxicology
    CRC Press, Boca Raton, FL, p. 67 - 85
  • Küster, A., Altenburger, R., (2011):
    Characeen als Objekte ökotoxikologischer Untersuchungen
    Ber. Bot. Arbeitsgem. Südwestdeutschland (Beiheft 3), 31 - 36
  • Rotter, S., Sans-Piché, F., Streck, G., Altenburger, R., Schmitt-Jansen, M., (2011):
    Active bio-monitoring of contamination in aquatic systems - an in situ translocation experiment applying the PICT concept
    Aquat. Toxicol. 101 (1), 228 - 236
    Volltext (URL)
  • Schreiber, R., Gündel, U., Franz, S., Küster, A., Rechenberg, B., Altenburger, R., (2011):
    Using the fish plasma model for comparative hazard identification for pharmaceuticals in the environment by extrapolation from human therapeutic data
    Regul. Toxicol. Pharmacol. 61 (3), 261 - 275
    Volltext (URL)
  • Schreiber, R., Küster, A., Feiler, U., Grote, M., Altenburger, R., (2011):
    A non-invasive observation parameter to complement sediment bioassays using Myriophyllum aquaticum
    J. Soils Sediments 11 (8), 1419 - 1431
    Volltext (URL)
  • Siegert, F., Erdmann, F., Schwan, G., Scholz, S., Briel, D., Altenburger, R., Nieber, K., (2011):
    Pharmacological and cytotoxic effects of new selective PDE10A ligands
    Naunyn-Schmiedebergs Arch. Pharmacol. 383 (Suppl. 1), 21 - 21
    Volltext (URL)

2010 (10)

  • Altenburger, R., Berns, A.E., Bittens, M., Brack, W., Burauel, P., Centler, F., Daus, B., Goss, K.-U., Harms, H., Kopinke, F.-D., Kühnel, D., Liess, M., Mackenzie, K., Miltner, A., Thullner, M., Wennrich, R., Wick, L.Y., (2010):
    Chemicals in the environment (CITE). Report of the First Annual Conference of the Helmholtz research topic CITE
    UWSF 22 (4), 502 - 506
    Volltext (URL)
  • Altenburger, R., Krüger, A., Eisenträger, A., (2010):
    Proposing a pH stabilised nutrient medium for algal growth bioassays
    Chemosphere 78 (7), 864 - 870
    Volltext (URL)
  • Bandow, N., Altenburger, R., Brack, W., (2010):
    Application of nd-SPME to determine freely dissolved concentrations in the presence of green algae and algae-water partition coefficients
    Chemosphere 79 (11), 1070 - 1076
    Volltext (URL)
  • Daus, B., Weiß, H., Altenburger, R., (2010):
    Uptake and toxicity of hexafluoroarsenate in aquatic organisms
    Chemosphere 78 (3), 307 - 312
    Volltext (URL)
  • Daus, B., Weiß, H., Wennrich, R., Altenburger, R., (2010):
    Are fluorine containing arsenic species an environmental problem?
    In: Jean, J.-S., Bundschuh, J., Bhattacharya, P., (eds.)
    Arsenic in geosphere and human diseases; Arsenic 2010: Proceedings of the Third International Congress on Arsenic in the Environment
    Taylor & Francis, London, p. 376 - 377
  • Gündel, U., Kalkhof, S., von Bergen, M., Altenburger, R., Küster, E., (2010):
    Concentration-response concept in ecotoxicoproteomics: an optimised design for the detection of robust chemical stress associated protein markers: Effects of different concentrations of phenanthren to the proteome of Danio rerio embryos
    Comp. Biochem. Physiol. A-Mol. Integr. Physiol. 157 (Suppl. 1), S42 - S43
    Volltext (URL)
  • Hanisch, K., Küster, E., Altenburger, R., Gündel, U., (2010):
    Proteomic signatures of the zebrafish (Danio rerio) embryo: sensitivity and specificity in toxicity assessment of chemicals
    International Journal of Proteomics 2010 , Article ID 630134 - 13
    Volltext (URL)
  • Sans-Piché, F., Kluender, C., Altenburger, R., Schmitt-Jansen, M., (2010):
    Anchoring metabolic changes to phenotypic effects in the chlorophyte Scenedesmus vacuolatus under chemical exposure
    Mar. Environ. Res. 69 (Suppl. 1), 528 - 530
    Volltext (URL)
  • Scholz, S., Schirmer, K., Altenburger, R., (2010):
    Pharmaceutical contaminants in urban water cycles - a discussion of novel concepts for environmental risk assessment
    In: Fata-Kassinos, D., Bester, K., Kümmerer, K., (eds.)
    Xenobiotics in the urban water cycle: mass flows, environmental processes and mitigation strategies
    Environ. Pollut. 16
    Springer, Heidelberg, p. 227 - 244
    Volltext (URL)
  • Schulze, T., Weiss, S., Schymanski, E., von der Ohe, P.C., Schmitt-Jansen, M., Altenburger, R., Streck, G., Brack, W., (2010):
    Identification of a phytotoxic photo-transformation product of diclofenac using effect-directed analysis
    Environ. Pollut. 158 (5), 1461 - 1466
    Volltext (URL)

2009 (8)

  • Altenburger, R., Greco, W.R., (2009):
    Extrapolation concepts for dealing with multiple contamination in environmental risk assessment
    Integr. Environ. Assess. Manag. 5 (1), 62 - 68
    Volltext (URL)
  • Altenburger, R., Gündel, U., Ali-Aycheh, M., Hanisch, K., Küster, A., Rechenberg, B., Schreiber, R., (2009):
    Models for extrapolation of long-term effects of pharmaceuticals in the environment using therapeutic information
    Toxicol. Lett. 189 (Suppl. 1), S191 - S192
    Volltext (URL)
  • Bandow, N., Altenburger, R., Lübcke-von Varel, U., Paschke, A., Streck, G., Brack, W., (2009):
    Partitioning-based dosing: an approach to include bioavailability in the effect-directed analysis of contaminated sediment samples
    Environ. Sci. Technol. 43 (10), 3891 - 3896
    Volltext (URL)
  • Bandow, N., Altenburger, R., Streck, G., Brack, W., (2009):
    Effect-directed analysis of contaminated sediments with partition-based dosing using green algae cell multiplication inhibition
    Environ. Sci. Technol. 43 (19), 7343 - 7349
    Volltext (URL)
  • Kluender, C., Sans-Piché, F., Riedl, J., Altenburger, R., Härtig, C., Laue, G., Schmitt-Jansen, M., (2009):
    A metabolomics approach to assessing phytotoxic effects on the green alga Scenedesmus vacuolatus
    Metabolomics 5 (1), 59 - 71
    Volltext (URL)
  • Rodil, R., Moeder, M., Altenburger, R., Schmitt-Jansen, M., (2009):
    Photostability and phytotoxicity of selected sunscreen agents and their degradation mixtures in water
    Anal. Bioanal. Chem. 395 (5), 1513 - 1524
    Volltext (URL)
  • Schreiber, R., Altenburger, R., Paschke, A., Schüürmann, G., Küster, E., (2009):
    A novel in vitro system for the determination of bioconcentration factors and the internal dose in zebrafish (Danio rerio) eggs
    Chemosphere 77 (7), 928 - 933
    Volltext (URL)
  • Schwab, K., Altenburger, R., Lübcke-von Varel, U., Streck, G., Brack, W., (2009):
    Effect-directed analysis of sediment-associated algal toxicants at selected hot spots in the river Elbe basin with a special focus on bioaccessibility
    Environ. Toxicol. Chem. 28 (7), 1506 - 1517
    Volltext (URL)

2008 (8)

  • Altenburger, R., Schmitt-Jansen, M., Riedl, J., (2008):
    Bioassays with unicellular algae: deviations from exponential growth and its implications for toxicity test results
    J. Environ. Qual. 37 (1), 16 - 21
    Volltext (URL)
  • Franz, S., Altenburger, R., Heilmeier, H., Schmitt-Jansen, M., (2008):
    What contributes to the sensitivity of microalgae to triclosan?
    Aquat. Toxicol. 90 (2), 102 - 108
    Volltext (URL)
  • Küster, E., Altenburger, R., (2008):
    Oxygen decline in biotesting of environmental samples - Is there a need for consideration in the acute zebrafish embryo assay?
    Environ.Toxicol. 23 (6), 745 - 750
    Volltext (URL)
  • Luckenbach, T., Altenburger, R., Epel, D., (2008):
    Teasing apart activities of different types of ABC efflux pumps in bivalve gills using the concepts of independent action and concentration addition
    Mar. Environ. Res. 66 (1), 75 - 76
    Volltext (URL)
  • McClellan, K., Altenburger, R., Schmitt-Jansen, M., (2008):
    Pollution-induced community tolerance as a measure of species interaction in toxicity assessment
    J. Appl. Ecol. 45 (5), 1514 - 1522
    Volltext (URL)
  • Schmitt-Jansen, M., Altenburger, R., (2008):
    Community-level microalgal toxicity assessment by multiwavelength-excitation PAM fluorometry
    Aquat. Toxicol. 86 (1), 49 - 58
    Volltext (URL)
  • Schmitt-Jansen, M., Veit, U., Dudel, G., Altenburger, R., (2008):
    An ecological perspective in aquatic ecotoxicology: approaches and challenges
    Basic Appl. Ecol. 9 (4), 337 - 345
    Volltext (URL)
  • Schreiber, R., Altenburger, R., Paschke, A., Küster, E., (2008):
    How to deal with lipophilic and volatile organic substances in microtiter plate assays
    Environ. Toxicol. Chem. 27 (8), 1676 - 1682
    Volltext (URL)

2007 (11)

  • Adler, N.E., Schmitt-Jansen, M., Altenburger, R., (2007):
    Flow cytometry as a tool to study phytotoxic modes of action
    Environ. Toxicol. Chem. 26 (2), 297 - 306
    Volltext (URL)
  • Bakker, J.F., Belzunce-Segarra, M.J., Castro, R., van de Heuvel-Greve, M., Klamer, H.J.C., Brack, W., Altenburger, R., Poulsen, V., Thomas, K.V., Leonards, P.E.G., (2007):
    Effect directed analysis and toxicity identification evaluation
    In: Barceló, D., Petrovic, M., (eds.)
    Sediment quality and impact assessment of pollutants
    Sustainable Management of Sediment Resources Vol. 1
    Elsevier, Amsterdam, p. 163 - 214
  • Gündel, U., Benndorf, D., von Bergen, M., Altenburger, R., Küster, E., (2007):
    Vitellogenin cleavage products as indicators for toxic stress in zebra fish embryos: a proteomic approach
    Proteomics 7 (24), 4541 - 4554
    Volltext (URL)
  • Küster, A., Altenburger, R., (2007):
    Development and validation of a new fluorescence-based bioassay for aquatic macrophyte species
    Chemosphere 67 (1), 194 - 201
    Volltext (URL)
  • Küster, A., Pohl, K., Altenburger, R., (2007):
    A fluorescence-based bioassay for aquatic macrophytes and its suitability for effect analysis of non-photosystem II inhibitors
    Environ. Sci. Pollut. Res. 14 (6), 377 - 383
    Volltext (URL)
  • Küster, E., Altenburger, R., (2007):
    Suborganismic and organismic effects of aldicarb and its metabolite aldicarb-sulfoxide to the zebrafish embryo (Danio rerio)
    Chemosphere 68 (4), 751 - 760
    Volltext (URL)
  • Pohl, K., Altenburger, R., Küster, A., (2007):
    Entwicklung und Etablierung eines Kurzzeit-Biotestsystems für aquatische Makrophyten
    Erweiterte Zusammenfassungen der Jahrestagung 2006 der Deutschen Gesellschaft für Limnologie (DGL) und der deutschen und österreichischen Sektion der Societas Internationalis Limnologiae (SIL). Dresden, 25. - 29.09.2006
    Deutsche Gesellschaft für Limnologie, Werder, S. 368 - 372
  • Riedl, J., Altenburger, R., (2007):
    Physicochemical substance properties as indicators for unreliable exposure in microplate-based bioassays
    Chemosphere 67 (11), 2210 - 2220
    Volltext (URL)
  • Schmitt-Jansen, M., Altenburger, R., (2007):
    The use of pulse-amplitude modulated (PAM) fluorescence-based methods to evaluate effects of herbicides in microalgal systems of different complexity
    Toxicol. Environ. Chem. 89 (4), 651 - 667
    Volltext (URL)
  • Schmitt-Jansen, M., Bartels, P., Adler, N., Altenburger, R., (2007):
    Phytotoxicity assessment of diclofenac and its phototransformation products
    Anal. Bioanal. Chem. 387 (4), 1389 - 1396
    Volltext (URL)
  • Tammer, B., Lehmann, I., Nieber, K., Altenburger, R., (2007):
    Combined effects of mycotoxin mixtures on human T cell function
    Toxicol. Lett. 170 (2), 124 - 133
    Volltext (URL)

2006 (2)

  • Altenburger, R., Brack, W., Greco, W.R., Grote, M., Jung, K., Ovari, A., Riedl, J., Schwab, K., Küster, E., (2006):
    On the mode of action of N-phenyl-2-naphthylamine in plants
    Environ. Sci. Technol. 40 (19), 6163 - 6169
    Volltext (URL)
  • Küster, E., Altenburger, R., (2006):
    Comparison of cholin- and carboxylesterase enzyme inhibition and visible effects in the zebra fish embryo bioassay under short-term paraoxon-methyl exposure
    Biomarkers 11 (4), 341 - 354
    Volltext (URL)

2005 (14)

  • Altenburger, R., Schmitt, H., Schüürmann, G., (2005):
    Algal toxicity of nitrobenzenes: combined effect analysis as a pharmacological probe for similar modes of interaction
    Environ. Toxicol. Chem. 24 (2), 324 - 333
    Volltext (URL)
  • Grote, M., Altenburger, R., Brack, W., Moschütz, S., Mothes, S., Michael, C., Narten, G.-B., Paschke, A., Schirmer, K., Walter, H.A., Wennrich, R., Wenzel, K.-D., Schüürmann, G., (2005):
    Ecotoxicological profiling of transect river Elbe sediments
    Acta Hydrochim. Hydrobiol. 33 (5), 555 - 569
    Volltext (URL)
  • Grote, M., Brack, W., Altenburger, R., (2005):
    Identification of toxicants from marine sediment using effect-directed analysis
    Environ.Toxicol. 20 (5), 475 - 486
    Volltext (URL)
  • Grote, M., Brack, W., Walter, H.A., Altenburger, R., (2005):
    Confirmation of cause-effect relationships using effect-directed analysis for complex environmental samples
    Environ. Toxicol. Chem. 24 (6), 1420 - 1427
    Volltext (URL)
  • Grote, M., Brack, W., Walter, H.A., Altenburger, R., (2005):
    Light as a confounding factor for toxicity assessment of complex contaminated sediments
    Environ. Toxicol. Chem. 24 (12), 3143 - 3152
    Volltext (URL)
  • Grote, M., Schüürmann, G., Altenburger, R., (2005):
    Modeling photoinduced algal toxicity of polycyclic aromatic hydrocarbons
    Environ. Sci. Technol. 39 (11), 4141 - 4149
    Volltext (URL)
  • Küster, E., Dorusch, F., Altenburger, R., (2005):
    Toxizität von Schwefelwasserstoff (H2S) auf die Biotestorganismen Vibrio fischeri und Daphnia magna
    Tagungsbericht 2004 der Deutschen Gesellschaft für Limnologie e.V. (DGL) und der Deutschsprachigen Sektion der Societas Internationalis Limnologiae (SIL). Potsdam, 20. - 24.09.2004
    Deutsche Gesellschaft für Limnologie, Berlin, S. 561 - 565
  • Küster, E., Dorusch, F., Altenburger, R., (2005):
    Effects of hydrogen sulfide to Vibrio fischeri, Scenedesmus vacuolatus, and Daphnia magna
    Environ. Toxicol. Chem. 24 (10), 2621 - 2629
    Volltext (URL)
  • Olajire, A.A., Altenburger, R., Küster, E., Brack, W., (2005):
    Chemical and ecotoxicological assessment of polycyclic aromatic hydrocarbon-contaminated sediments of the Niger Delta, Southern Nigeria
    Sci. Total Environ. 340 (1-3), 123 - 136
    Volltext (URL)
  • Schmitt-Jansen, M., Altenburger, R., (2005):
    Predicting and observing responses of algal communities to photosystem II-herbicide exposure using pollution-induced community tolerance and species-sensitivity distributions
    Environ. Toxicol. Chem. 24 (2), 304 - 312
    Volltext (URL)
  • Schmitt-Jansen, M., Altenburger, R., (2005):
    Lassen sich Ergebnisse aus ökotoxikologischen Einzelartentests auf aquatische Lebensgemeinschaften extrapolieren?
    Tagungsbericht 2004 der Deutschen Gesellschaft für Limnologie e.V. (DGL) und der Deutschsprachigen Sektion der Societas Internationalis Limnologiae (SIL). Potsdam, 20. - 24.09.2004
    Deutsche Gesellschaft für Limnologie, Berlin, S. 556 - 560
  • Schmitt-Jansen, M., Altenburger, R., (2005):
    Toxic effects of isoproturon on periphyton communities - a microcosm study
    Estuar. Coast. Shelf Sci. 62 (3), 539 - 545
    Volltext (URL)
  • von der Ohe, P.C., Kühne, R., Ebert, R.U., Altenburger, R., Liess, M., Schüürmann, G., (2005):
    Structural alerts - a new classification model to discriminate excess toxicity from narcotic effect levels of organic compounds in the acute daphnid assay
    Chem. Res. Toxicol. 18 (3), 536 - 555
    Volltext (URL)
  • Wollin, K.M., Altenburger, R., Altmayer, M., Dieter, H.H., Moll, B., Six, E., von der Trenck, K.T., (2005):
    (ECO)toxicological insignificance thresholds for risk assessment of polluted groundwater
    Naunyn-Schmiedebergs Arch. Pharmacol. 371 (Suppl. 1), R133 - R134

2004 (9)

  • Altenburger, R., Walter, H., Grote, M., (2004):
    What contributes to the combined effect of a complex mixture?
    Environ. Sci. Technol. 38 (23), 6353 - 6362
    Volltext (URL)
  • Bopp, S., Schirmer, M., Russold, S., Altenburger, R., Schirmer, K., (2004):
    Combined chemical/biological monitoring as part of assessing natural attenuation at a BTEX-contaminated megasite
    In: Magar, V.S., Kelley, M.E., (eds.)
    7th International In Situ and On-Site Bioremediation Symposium, Orlando/USA, 2.-5.6.2003
    Battelle Press, Columbus, OH, p. Paper H32
  • Grote, M., Altenburger, R., Brack, W., Möckel, C., Moschütz, S., Mothes, S., Michael, C., Narten, G.-B., Paschke, A., Schirmer, K., Walter, H., Wennrich, R., Wenzel, K.-D., Schüürmann, G., (2004):
    Identifizierung und Analyse des ökotoxischen Potentials von Flusssedimenten als Folge der durch Hochwasser mobilisierten Kontamination
    In: Geller, W., Ockenfeld, K., Böhme, M., Knöchel, A., (Hrsg.)
    Schadstoffbelastung nach dem Elbe-Hochwasser 2002. Endbericht des Ad-hoc-Verbundprojekts
    UFZ Leipzig-Halle GmbH, Magdeburg, S. 314 - 329
  • Grote, M., Walter, H., Altenburger, R., (2004):
    Toxizitätsuntersuchungen von Elbsedimenten in Kontakttesten mit Lemna minor und Danio rerio
    Statusseminar Sedimentskontakttests : 24./25. März 2004 in Koblenz
    Veranstaltungen / BfG 5/2004
    Bundesanstalt für Gewässerkunde, Koblenz, S. 25 - 35
  • Krumm, B., Altenburger, R., Nieber, K., Lehmann, I., (2004):
    Low concentration of mycotoxins with weak effects as single compounds mediate strong inhibition of IFN-gamma release when exposed together
    Immunobiology 209 (4-6), 470
    Volltext (URL)
  • Küster, E., Dorusch, F., Altenburger, R., (2004):
    Ökotoxikologische Verfahren der Wirkungsanalyse für das Management von Grundwasser-Kontaminationen: Fallbeispiel quartärer Grundwasserleiter in Bitterfeld-Süd
    In: Weiß, H., Teutsch, G., Daus, B., (Hrsg.)
    SAFIRA (Sanierungsforschung in regional kontaminierten Aquiferen)
    UFZ-Bericht 13/2004
    UFZ Leipzig-Halle GmbH, Leipzig, S. 287 - 316
    Volltext (PDF)
  • Küster, E., Dorusch, F., Vogt, C., Weiß, H., Altenburger, R., (2004):
    On line biomonitors used as a tool for toxicity reduction evaluation of in situ groundwater remediation techniques
    Biosens. Bioelectron. 19 (12), 1711 - 1722
    Volltext (URL)
  • Schmitt-Jansen, M., Küster, A., Altenburger, R., (2004):
    Untersuchung schadstofftoleranter Aufwuchsgemeinschaften als ein Instrument zur Bewertung von Schadstoffen in Gewässern
    Tagungsbericht 2002 der Deutschen Gesellschaft für Limnologie (DGL) und der deutschen und österreichischen Sektion der Societas Internationionalis Limnologiae (SIL). Band II, Braunschweig, 30.9.-4.10.2002
    Deutsche Gesellschaft für Limnologie, Werder, p. 621 - 626
  • Schmitt-Jansen, M., Reiners, S., Altenburger, R., (2004):
    Biozönotische Testverfahren (PICT-Konzept). Analyse von Schadstoff-induzierten Effekten in Gewässern mit autotrophen Aufwuchszönosen
    UWSF 16 (2), 85 - 91
    Volltext (URL)

2003 (12)

  • Altenburger, R., Brack, W., Grote, M., Moschütz, S., Paschke, A., Schirmer, K., Walter, H., Wenzel, K., Schüürmann, G., (2003):
    Identifizierung und Analyse des ökotoxikologischen Potentials von Flußsedimenten als Folge der durch Hochwasser mobilisierten Kontaminationen
    Schadstoffbelastung im Mulde- und Elbe-Einzugsgebiet nach dem Augusthochwasser 2002,
    Ergebnisse und Forschungsbedarf, Tagungsband. Statusseminar des BMBF-Ad-hoc-Verbundprojektes, Freiberg, 27.-29. August 2003

    UFZ Leipzig-Halle GmbH, Magdeburg, p. 9 - 12
  • Altenburger, R., Nendza, M., Schüürmann, G., (2003):
    Mixture toxicity and its modeling by quantitative structure-activity relationships
    Environ. Toxicol. Chem. 22 (8), 1900 - 1915
    Volltext (URL)
  • Altenburger, R., Schmitt-Jansen, M., (2003):
    Predicting toxic effects of contaminants in ecosystems using single species investigations
    In: Breure, A.M., Markert, B.A., Zechmeister, H.G., (eds.)
    Bioindicators & biomonitors. Principles, concepts and applications
    Trace Metals and other Contaminants in the Environment 6
    Elsevier, Amsterdam, p. 153 - 198
  • Altenburger, R., Segner, H., van der Oost, R., (2003):
    Biomarkers and PAHs - prospects for the assessment of exposure and effects in aquatic systems
    In: Douben, P.E.T., (ed.)
    PAHs: an ecotoxicological perspective
    Ecological and Environmental Toxicology Series
    Wiley, Chichester, p. 297 - 328
  • Backhaus, T., Altenburger, R., Arrhenius, A., Blanck, H., Faust, M., Finizio, A., Gramatica, P., Grote, M., Junghans, M., Meyer, W., Pavan, M., Porsbring, T., Scholze, M., Todeschini, R., Vighi, M., Walter, H., Grimme, L.H., (2003):
    The BEAM-project: prediction and assessment of mixture toxicities in the aquatic environment
    Cont. Shelf Res 23 (17-19), 1757 - 1769
    Volltext (URL)
  • Brack, W., Altenburger, R., Küster, E., Meissner, B., Wenzel, K.-D., Schüürmann, G., (2003):
    Identification of toxic products of anthracene photomodification in simulated sunlight
    Environ. Toxicol. Chem. 22 (10), 2228 - 2237
    Volltext (URL)
  • Faust, M., Altenburger, R., Backhaus, T., Blanck, H., Boedeker, W., Gramatica, P., Hamer, V., Scholze, M., Vighi, M., Grimme, L.H., (2003):
    Joint algal toxicity of 16 dissimilarly acting chemicals is predictable by the concept of independent action
    Aquat. Toxicol. 63 (1), 43 - 63
    Volltext (URL)
  • Küster, E., Dorusch, F., Meißner, B., Weiß, H., Schüürmann, G., Altenburger, R., (2003):
    Toxizitätsreduktion durch (Grundwasser-) Sanierung?
    Grundwasser 8 (1), 32 - 40
    Volltext (URL)
  • Küster, E., Dorusch, F., Weiß, H., Altenburger, R., (2003):
    Controlling (groundwater-) remediation success via on line biomonitoring or how toxic is remediated groundwater?
    ConSoil 2003 : proceedings of the 8th International FZK/TNO Conference on Contaminated Soil, ICC Gent, Belgium, 12 - 16 May 2003
    F&U confirm, Leipzig, p. 3305 - 3314
  • Küster, E., Dorusch, F., Weiß, H., Schüürmann, G., Altenburger, R., (2003):
    Beurteilung der Entgiftung von Grundwasser durch Sanierungsverfahren mittels kontinuierlicher biologischer Überwachung
    In: Foth, H., (Hrsg.)
    Risk assessment and management of large contamination sites. Gefahrenabschätzung und Handhabung großflächiger Kontaminationen. Proceedingsband zum Kongress an der Martin-Luther-Universität Halle-Wittenberg, 22. - 24. Februar 2002
    S. 41 - 45
  • Schirmer, K., Altenburger, R., Bopp, S., Weiß, H., (2003):
    Toxikologische Überwachung beim Einsatz von "Natural Attenuation" als Sanierungsoption
    In: Foth, H., (Hrsg.)
    Risk assessment and management of large contamination sites. Gefahrenabschätzung und Handhabung großflächiger Kontaminationen. Proceedingsband zum Kongress an der Martin-Luther-Universität Halle-Wittenberg, 22. - 24. Februar 2002
    S. 33 - 36
  • Vighi, M., Altenburger, R., Arrhenius, A., Backhaus, T., Bödeker, W., Blanck, H., Consolaro, F., Faust, M., Finizio, A., Froehner, K., Gramatica, P., Grimme, L.H., Grönvall, F., Hamer, V., Scholze, M., Walter, H., (2003):
    Water quality objectives for mixtures of toxic chemicals: problems and perspectives
    Ecotox. Environ. Safe. 54 (2), 139 - 150
    Volltext (URL)

2002 (7)

  • Altenburger, R., (2002):
    Predicting toxic effects of contaminants in ecosystems using single species investigations
    Habilitation, Universität Bremen, Fachbereich Biologie und Chemie
    206 pp.
  • Brack, W., Altenburger, R., (2002):
    Effektorientierte Identifikation toxischer Verbindungen
    Mitteilungen der Fachgruppe Umweltchemie und Ökotoxikologie / Gesellschaft Deutscher Chemiker 8 , 6 - 8
  • Brack, W., Altenburger, R., Dorusch, F., Hubert, A., Möder, M., Morgenstern, P., Moschütz, S., Mothes, S., Schirmer, K., Wennrich, R., Wenzel, K.-D., Schüürmann, G., (2002):
    Hochwasser 2002 - Chemische und toxische Belastung überschwemmter Gemeinden im Raum Bitterfeld
    UWSF 14 (4), 213 - 220
    Volltext (URL)
  • Cleuvers, M., Altenburger, R., Ratte, H.T., (2002):
    Combination effect of light and toxicity in algal tests
    J. Environ. Qual. 31 (2), 539 - 547
    Volltext (URL)
  • Meene, R., Schüürmann, G., Altenburger, R., (2002):
    pH-abhängige Algentoxizität von Phenolderivaten
    Mitteilungen der Fachgruppe Umweltchemie und Ökotoxikologie / Gesellschaft Deutscher Chemiker 8 , 9 - 11
  • Schirmer, K., Altenburger, R., Bopp, S.K., Weiß, H., (2002):
    Toxicological monitoring for the assessment of natural attenuation as a remediation option
    International conference on Risk Assessment of Large Contaminated Sites, Halle, Germany, 22.-23.2.2002
  • Walter, H., Consolaro, F., Gramatica, P., Scholze, M., Altenburger, R., (2002):
    Mixture toxicity of priority pollutants at no observed effect concentrations (NOECs)
    Ecotoxicology 11 (5), 299 - 310
    Volltext (URL)

2001 (5)

  • Faust, M., Altenburger, R., Backhaus, T., Blanck, H., Bödeker, W., Gramatica, P., Hamer, V., Scholze, M., Vighi, M., Grimme, L.H., (2001):
    Predicting the joint algal toxicity of multi-component s-triazine mixtures at low-effect concentrations of individual toxicants
    Aquat. Toxicol. 56 (1), 13 - 32
    Volltext (URL)
  • Knops, M., Altenburger, R., Segner, H., (2001):
    Alterations of physiological energetics, growth and reproduction of Daphnia magna under toxicant stress
    Aquat. Toxicol. 53 (2), 79 - 90
    Volltext (URL)
  • Küster, E., Dorusch, F., Weiß, H., Altenburger, R., (2001):
    TRE-Toxicity-Reduction-Evaluation - Approaches for continuous effect monitoring of in situ groundwater remediation techniques
    11th Annual Meeting of the Society of Environmental Toxicology and Chemistry (SETAC) Europe, Madrid, Spain, 6-10 May 2001
    SETAC Europe, Brussels,
  • Scholze, M., Boedeker, W., Faust, M., Backhaus, T., Altenburger, R., Grimme, L.H., (2001):
    A general best-fit method for concentration-response curves and the estimation of low-effect concentrations
    Environ. Toxicol. Chem. 20 (2), 448 - 457
    Volltext (URL)
  • Segner, H., Altenburger, R., Jung, K., Schüürmann, G., (2001):
    Ecotoxicity characterization of seepage waters from a Theisenschlamm pond discharging into riverine system
    In: Daus, B., Weiß, H., (eds.)
    Fine-grained residues from copper smelting and their environmental impacts
    UFZ-Bericht 22/2001
    UFZ Leipzig-Halle GmbH, Leipzig, p. 59 - 69
    Volltext (PDF)

2000 (11)

  • Altenburger, R., Backhaus, T., Boedeker, W., Faust, M., Scholze, M., Grimme, L.H., (2000):
    Predictability of the toxicity of multiple chemical mixtures to Vibrio fischeri: Mixtures composed of similarly acting chemicals
    Environ. Toxicol. Chem. 19 (9), 2341 - 2347
    Volltext (URL)
  • Altenburger, R., Backhaus, T., (2000):
    Exposition und Toxizität - Der Faktor Zeit in Routinebiotests
    In: Mücke, W., Link, M., (Hrsg.)
    Biotests in der Praxis - Status und Perspektiven in Methodik und Anwendung
    TU München, Institut für Toxikologie und Umwelthygiene; Dr. Bruno Lange GmbH Düsseldorf, S. 61 - 74
  • Altenburger, R., Segner, H., (2000):
    Anwendungen biologischer Testverfahren für ökotoxikologische Wirkungsanalysen
    In: Fomin, A., Arndt, U., Elsner, D., Klumpp, A., (Hrsg.)
    Bioindikation: Biologische Testverfahren. Beiträge und Diskussion - 2. Hohenheimer Workshop zur Bioindikation am Kraftwerk Altbach-Deizisau, 6.4.1998
    Heimbach, Stuttgart, S. 23 - 31
  • Backhaus, T., Altenburger, R., Boedeker, W., Faust, M., Scholze, M., Grimme, L.H., (2000):
    Predictability of the toxicity of multiple chemical mixtures of dissimilarly acting chemicals to Vibrio fischeri
    Environ. Toxicol. Chem. 19 (9), 2348 - 2356
    Volltext (URL)
  • Brack, W., Altenburger, R., (2000):
    Identifikation giftiger Inhaltsstoffe - ein wichtiger Schritt zur Gefährdungsabschätzung und Sanierung
    UFZ-Jahresbericht '98-'99
    UFZ Leipzig-Halle GmbH, Leipzig, S. 26 - 34
    Volltext (PDF)
  • Brack, W., Altenburger, R., Ensenbach, U., Nehls, S., Segner, H., (2000):
    Biotestorientierte Identifikation toxischer organischer Sedimentinhaltstoffe - Ein Beitrag zur Risikoanalyse komplexer Kontaminationen am Beispiel des Spittelwassers. Mitteilung Nr. 22. Sedimentbewertung in europäischen Flußgebieten. Beiträge zum internationalen Symposium vom 12.-14. April 1999
    "Sedimentbewertung in europäischen Flußgebieten", Koblenz, 12.-14.4.1999
    Bundesanstalt für Gewässerkunde, Koblenz, p. 135 - 141
  • Brack, W., Altenburger, R., Ensenbach, U., Nehls, S., Segner, H., Schüürmann, G., (2000):
    Wirkungsorientierte Identifikation toxischer organischer Inhaltsstoffe in Flußsedimenten
    In: Friese, K., Witter, B., Miehlich, G., Rode, M., (Hrsg.)
    Stoffhaushalt von Auenökosystemen. Böden und Hydrologie, Schadstoffe, Bewertungen
    Springer, Berlin, Heidelberg, New York, S. 337 - 346
    Volltext (URL)
  • Faust, M., Altenburger, R., Backhaus, T., Boedeker, W., Scholze, M., Grimme, L.H., (2000):
    Predictive assessment of the aquatic toxicity of multiple chemical mixtures
    J. Environ. Qual. 29 (4), 1063 - 1068
    Volltext (URL)
  • Grimme, L.H., Altenburger, R., Backhaus, T., Faust, M., Bödeker, W., Scholze, M., (2000):
    Kombinationswirkungen von Umweltchemikalien in der Ökotoxikologie. Konzepte für die Vorhersage und ihre experimentelle Prüfung
    UWSF 12 , 226 - 234
    Volltext (URL)
  • Hafner, C., Jung, K., Gehre, M., Altenburger, R., Schüürmann, G., (2000):
    Isotopenmassenspektrometrische 13C/15N-Traceruntersuchungen zur Wirkung von Chlororganika auf höhere Pflanzen am Beispiel von Pentachlorphenol
    In: Fomin, A., Arndt, U., Elsner, D., Klumpp, A., (Hrsg.)
    Bioindikation: Biologische Testverfahren. Beiträge und Diskussion - 2. Hohenheimer Workshop zur Bioindikation am Kraftwerk Altbach-Deizisau, 6.4.1998
    Heimbach, Stuttgart, S. 199 - 204
  • Schmitt, H., Altenburger, R., Jastorff, B., Schüürmann, G., (2000):
    Quantitative structure-activity analysis of the algae toxicity of nitroaromatic compounds
    Chem. Res. Toxicol. 13 (6), 441 - 450
    Volltext (URL)

1999 (4)

  • Brack, W., Altenburger, R., Ensenbach, U., Möder, M., Segner, H., Schüürmann, G., (1999):
    Bioassay-directed identification of organic toxicants in river sediment in the industrial region of Bitterfeld (Germany) - a contribution to hazard assessment
    Arch. Environ. Contam. Toxicol 37 (2), 164 - 174
    Volltext (URL)
  • Kortenkamp, A., Altenburger, R., (1999):
    Approaches to assessing combination effects of oestrogenic environmental pollutants
    Sci. Total Environ. 233 (1-3), 131 - 140
    Volltext (URL)
  • Praszczyk, B., Altenburger, R., Oehlmann, J., Markert, B., Schüürmann, G., (1999):
    Brauchen wir einen Biotest mit höheren Pflanzen in der aquatischen Toxikologie?
    In: Oehlmann, J., Markert, B., (Hrsg.)
    Ökotoxikologie - Ökosystemare Ansätze und Methoden
    ecomed, Landsberg am Lech, S. 151 - 163
  • Schüürmann, G., Altenburger, R., Segner, H., (1999):
    Trendberichte Ökotoxikologie
    Nachr. Chem., Tech. Lab. 47 (3), 295 - 302
    Volltext (URL)

1998 (5)

  • Brack, W., Altenburger, R., Ensenbach, U., Nehls, S., Segner, H., Schüürmann, G., (1998):
    Identifikation ökotoxikologisch wirksamer Substanzen in Sedimenten des Spittelwassers
    In: Geller, W., Punčochář, P., Bornhöft, D., Bouček, J., Feldmann, H., Guhr, H., Mohaupt, V., Simon, M., Smrtˇák, J., Spoustová, J., Uhlmann, O., (Hrsg.)
    Gewässerschutz im Einzugsgebiet der Elbe. 8. Magdeburger Gewässerschutzseminar, Oktober 1998, Karlsbad (Tschechien)
    B.G. Teubner, Stuttgart, Leipzig, S. 149 - 150
    Volltext (URL)
  • Ensenbach, U., Altenburger, R., Behrens, A., Brack, W., Knops, M., Navas, J.M., Nehls, S., Schrag, B., Segner, H., Sturm, A., Walter, H., Schüürmann, G., (1998):
    Ökotoxikologische Analyse komplexer Stoffgemische
    Tagungsbericht 1997 der Deutschen Gesellschaft für Limnologie (DGL) und der deutschen und österreichischen Sektion der Societas Internationalis Limnologiae (SIL). Band II, Frankfurt am Main, 22. - 26.9.1997
    Deutsche Gesellschaft für Limnologie, Krefeld, p. 882 - 885
  • Ensenbach, U., Altenburger, R., Brack, W., Paschke, A., Popp, P., Segner, H., Wennrich, R., Schüürmann, G., (1998):
    Ökotoxikologische Charakterisierung von Sedimenten der Saale
    In: Geller, W., Punčochář, P., Bornhöft, D., Bouček, J., Feldmann, H., Guhr, H., Mohaupt, V., Simon, M., Smrtˇák, J., Spoustová, J., Uhlmann, O., (Hrsg.)
    Gewässerschutz im Einzugsgebiet der Elbe. 8. Magdeburger Gewässerschutzseminar, Oktober 1998, Karlsbad (Tschechien)
    B.G. Teubner, Stuttgart, Leipzig, S. 151 - 152
    Volltext (URL)
  • Grimme, L.H., Altenburger, R., Backhaus, T., Bödeker, W., Faust, M., Scholze, M., (1998):
    Vorhersagbarkeit und Beurteilung der aquatischen Toxizität von Stoffgemischen - Multiple Kombinationen von unähnlich wirkenden Substanzen in niedrigen Konzentrationen
    UFZ-Bericht 25/1998
    UFZ Leipzig-Halle GmbH, Leipzig, 319 S.
  • Kortenkamp, A., Altenburger, R., (1998):
    Synergisms with mixtures of xenoestrogens: A reevaluation using the method of isoboles
    Sci. Total Environ. 221 (1), 59 - 73
    Volltext (URL)

1997 (5)

  • Altenburger, R., Ensenbach, U., Jung, K., Knops, M., Popp, P., Segner, H., Weiß, H., Schüürmann, G., (1997):
    Ecotoxicity identification for the hazard characterization of groundwater contamination: a fingerprint approach for a contaminated site at Bitterfeld
    In: Alef, K., Brandt, J., Fiedler, H., Hauthal, W., Hutzinger, O., Mackay, D., Matthies, M., Morgan, K., Newland, L., Robitaille, H., Schlummer, M., Schüürmann, G., Voigt, K., (eds.)
    Information and Communication in Environmental and Health Issues. ECO-INFORMA '97, 6.-9.10.1997, Neuherberg
    Eco-Informa Vol. 12
    Eco-Informa Press, Bayreuth, p. 452 - 457
  • Altenburger, R., Ensenbach, U., Jung, K., Knops, M., Segner, H., (1997):
    Ökotoxikologische Untersuchungen an Grundwasserproben
    In: Weiß, H., Teutsch, G., Daus, B., (Hrsg.)
    Sanierungsforschung in regional kontaminierten Aquiferen (SAFIRA): Bericht zur Machbarkeitsstudie für den Modellstandort Bitterfeld
    UFZ-Bericht 27/1997
    UFZ Leipzig-Halle GmbH, Leipzig, S. 94 - 98
    Volltext (PDF)
  • Altenburger, R., Schüürmann, G., (1997):
    Instrumentarien zur Bewertung möglicher Kombinationswirkungen von Schadstoffen auf die menschliche Gesundheit
    Integrierte Bewertung radiologischer und chemisch-toxischer Kontaminanten: Workshop am 24.11.1997
    Sächsisches Staatsministerium für Umwelt und Landesentwicklung, Dresden, p. 27 - 35
  • Backhaus, T., Froehner, K., Altenburger, R., Grimme, L.H., (1997):
    Toxicity testing with Vibrio fischeri: A comparison between the long term (24 h) and the short term (30 min) bioassay
    Chemosphere 35 (12), 2925 - 2938
    Volltext (URL)
  • Leibfritz, D., Altenburger, R., (1997):
    Cell suspensions
    In: Grant, D.M., Harris, R.K., (eds.)
    Encyclopedia of nuclear magnetic resonance. Vol. 2
    Wiley, New York, p. 1197 - 1209