Prof. Dr. Rolf Altenburger
Adresse:
Permoserstr. 15
04318 Leipzig
Gebäude: 6.0
Raum: 317
Telefon: +49 341 235 1285
Dr. Rolf Altenburger
Curriculum Vitae
Rolf Altenburger is Head of the Department Bioanalytical Ecotoxicology since 2005. He holds a professorship at the RWTH Aachen University, Institute for Environmental Research. His professional activities comprise the Editorial Board of Environmental Pollution, Membership in advisory groups, e.g. on the German plant protection action plan or being speaker of the HGF programme topic Chemicals in the Environment (CITE).
Rolf Altenburger received his Doctor of Science from the University of Bremen. Previous to his appointment at the RWTH Aachen he held a venia legendi at the University of Bremen and the TU Bergakademie Freiberg. His professional training as a biologist included studies at the Universities of Marburg, Freiburg, and Bremen, Germany, and St.Andrews, Scotland. He obtained research fellowships to Shabat Alam Malaysia, Penang, Malaysa; Visaya State College of Agriculture, Leyte, The Philippines; Roswell Park Cancer Institute, Buffalo, NY, USA; and the National Research Centre for Environmental Toxicology (ENTOX), Brisbane, Australia.
Rolf Altenburger’s research interests focus on
- Mixture toxicity assessment for complex environmental exposure;
- Bioassays for toxicant identification at multiple contaminated sites;
- Mode-of-action analysis for toxicants;
- Pharmacokinetic-pharmacodynamic (PKPD) models to mechanistically describe concentration and time dependent toxicity.
Traditional chemicals risk assessment considers chemicals one by one while organisms in the environment typically are confronted with exposure to multiple substances. For more than a decade, we have been investigating mixture effects to improve environmental risk assessment. Milestones in our work comprise answers to the following questions: Can we establish bioassays that allow detection of combination effects? For several ecotoxicity assays from subcellular to community level we could successfully demonstrate this. Secondly, can we predict mixture toxicity based on the information about the components biological activities? For apical effects and an array of mixtures of environmental contaminants we could support the notion that extrapolative modelling is indeed possible. The more precise the prediction is needed, the more mechanism-based information is required. Currently, want to extend our knowledge in two directions: namely the understanding of mixture interactions at a molecular level (Exposome) and the combined effects under conditions of multiple stress.
Publikationen
2019 (15)
- Altenburger, R., Brack, W., Burgess, R.M., Busch, W., Escher, B.I., Focks, A., Hewitt, L.M., Jacobsen, B.N., López de Alda, M., Ait-Aissa, S., Backhaus, T., Ginebreda, A., Hilscherová, K., Hollender, J., Hollert, H., Neale, P.A., Schulze, T., Schymanski, E.L., Teodorovic, I., Tindall, A.J., De Aragão Umbuzeiro, G., Vrana, B., Zonja, B., Krauss, M., (2019):
Future water quality monitoring: improving the balance between exposure and toxicity assessments of real-world pollutant mixtures
Environ. Sci. Eur. 31 , art. 12
Volltext (DOI) - Brack, W., Ait-Aissa, S., Altenburger, R., Cousins, I., Dulio, V., Escher, B., Focks, A., Ginebreda, A., Hering, D., Hilscherová, K., Hollender, J., Hollert, H., Kortenkamp, A., López de Alda, M., Posthuma, L., Schymanski, E., Segner, H., Slobodnik, J., (2019):
Let us empower the WFD to prevent risks of chemical pollution in European rivers and lakes
Environ. Sci. Eur. 31 , art. 47
Volltext (DOI) - Brack, W., Ait‑Aissa, S., Backhaus, T., Birk, S., Barceló, D., Burgess, R., Cousins, I., Dulio, V., Escher, B.I., Focks, A., van Gils, J., Ginebreda, A., Hering, D., Hewitt, L.M., Hilscherová, K., Hollender, J., Hollert, H., Köck, M., Kortenkamp, A., López de Alda, M., Müller, C., Posthuma, L., Schüürmann, G., Schymanski, E., Segner, H., Sleeuwaert, F., Slobodnik, J., Teodorovic, I., Umbuzeiro, G., Voulvoulis, N., van Wezel, A., Altenburger, R., (2019):
Strengthen the European collaborative environmental research to meet European policy goals for achieving a sustainable, non‑toxic environment
Environ. Sci. Eur. 31 , art. 63
Volltext (DOI) - Brack, W., Ait-Aissa, S., Backhaus, T., Dulio, V., Escher, B.I., Faust, M., Hilscherova, K., Hollender, J., Hollert, H., Müller, C., Munthe, J., Posthuma, L., Seiler, T.-B., Slobodnik, J., Teodorovic, I., Tindall, A.J., De Aragão Umbuzeiro, G., Zhang, X., Altenburger, R., (2019):
Effect‑based methods are key. The European Collaborative Project SOLUTIONS recommends integrating effect‑based methods for diagnosis and monitoring of water quality
Environ. Sci. Eur. 31 , art. 10
Volltext (DOI) - Brack, W., Altenburger, R., (2019):
Projekt Solutions: Mikroschadstoffe in europäischen Gewässern
Wasserwirtschaft, Wassertechnik : wwt (4), 15 - 20 - Faust, M., Backhaus, T., Altenburger, R., Dulio, V., van Gils, J., Ginebreda, A., Kortenkamp, A., Munthe, J., Posthuma, L., Slobodnik, J., Tollefsen, K.E., van Wezel, A., Brack, W., (2019):
Prioritisation of water pollutants: the EU Project SOLUTIONS proposes a methodological framework for the integration of mixture risk assessments into prioritisation procedures under the European Water Framework Directive
Environ. Sci. Eur. 31 , art. 66
Volltext (DOI) - Kortenkamp, A., Faust, M., Backhaus, T., Altenburger, R., Scholze, M., Müller, C., Ermler, S., Posthuma, L., Brack, W., (2019):
Mixture risks threaten water quality: the European Collaborative Project SOLUTIONS recommends changes to the WFD and better coordination across all pieces of European chemicals legislation to improve protection from exposure of the aquatic environment to multiple pollutants
Environ. Sci. Eur. 31 , art. 96
Volltext (DOI) - Leuthold, D., Klüver, N., Altenburger, R., Busch, W., (2019):
Can environmentally relevant neuroactive chemicals specifically be detected with the locomotor response test in zebrafish embryos?
Environ. Sci. Technol. 53 (1), 482 - 493
Volltext (DOI) - Munthe, J., Lexén, J., Skårman, T., Posthuma, L., Brack, W., Altenburger, R., Brorström‑Lundén, E., Bunke, D., Faust, M., Rahmberg, M., Sleeuwaert, F., Slobodnik, J., van Gils, J., van Wezel, A., (2019):
Increase coherence, cooperation and cross‑compliance of regulations on chemicals and water quality
Environ. Sci. Eur. 31 , art. 64
Volltext (DOI) - Posthuma, L., Altenburger, R., Backhaus, T., Kortenkamp, A., Müller, C., Focks, A., de Zwart, D., Brack, W., (2019):
Improved component‑based methods for mixture risk assessment are key to characterize complex chemical pollution in surface waters
Environ. Sci. Eur. 31 , art. 70
Volltext (DOI) - Posthuma, L., Munthe, J., van Gils, J., Altenburger, R., Müller, C., Slobodnik, J., Brack, W., (2019):
A holistic approach is key to protect water quality and monitor, assess and manage chemical pollution of European surface waters
Environ. Sci. Eur. 31 , art. 67
Volltext (DOI) - Schäfer, R.B., Liess, M., Altenburger, R., Filser, J., Hollert, H., Roß-Nickoll, M., Schäffer, A., Scheringer, M., (2019):
Future pesticide risk assessment: narrowing the gap between intention and reality
Environ. Sci. Eur. 31 , art. 21
Volltext (DOI) - Schmidt, S., Altenburger, R., Kühnel, D., (2019):
From the air to the water phase: implication for toxicity testing of combustion-derived particles
Biomass Convers. Biorefinery 9 (1), 213 - 225
Volltext (DOI) - Schüttler, A., Altenburger, R., Ammar, M., Bader-Blukott, M., Jakobs, G., Knapp, J., Krüger, J., Reiche, K., Wu, G.-M., Busch, W., (2019):
Map and model—moving from observation to prediction in toxicogenomics
GigaScience 8 (6), giz057
Volltext (DOI) - Serra, H., Scholze, M., Altenburger, R., Busch, W., Budzinski, H., Brion, F., Aït-Aïssa, S., (2019):
Combined effects of environmental xeno-estrogens within multi-component mixtures: Comparison of in vitro human- and zebrafish-based estrogenicity bioassays
Chemosphere 227 , 334 - 344
Volltext (DOI)
2018 (5)
- Altenburger, R., Scholze, M., Busch, W., Escher, B.I., Jakobs, G., Krauss, M., Krüger, J., Neale, P.A., Ait-Aissa, S., Almeida, A.C., Seiler, T.-B., Brion, F., Hilscherová, K., Hollert, H., Novák, J., Schlichting, R., Serra, H., Shao, Y., Tindall, A., Tolefsen, K.-E., Umbuzeiro, G., Williams, T.D., Kortenkamp, A., (2018):
Mixture effects in samples of multiple contaminants – An inter-laboratory study with manifold bioassays
Environ. Int. 114 , 95 - 106
Volltext (DOI) - Diamond, J., Altenburger, R., Coors, A., Dyer, S.D., Focazio, M., Kidd, K., Koelmans, A.A., Leung, K.M.Y., Servos, M.R., Snape, J., Tolls, J., Zhang, X., (2018):
Use of prospective and retrospective risk assessment methods that simplify chemical mixtures associated with treated domestic wastewater discharges
Environ. Toxicol. Chem. 37 (3), 690 - 702
Volltext (DOI) - Naasz, S., Altenburger, R., Kühnel, D., (2018):
Environmental mixtures of nanomaterials and chemicals: The Trojan-horse phenomenon and its relevance for ecotoxicity
Sci. Total Environ. 635 , 1170 - 1181
Volltext (DOI) - Scholz, S., Schreiber, R., Armitage, J., Mayer, P., Escher, B.I., Lidzba, A., Léonard, M., Altenburger, R., (2018):
Meta‐analysis of fish early life stage tests—Association of toxic ratios and acute‐to‐chronic ratios with modes of action
Environ. Toxicol. Chem. 37 (4), 955 - 969
Volltext (DOI) - Whalley, C., Mohaupt, V., Busch, W., van den Roovaart, J., van Dujnhoven, N., Kirst, I., Schmedtje, U., Altenburger, R., Sommer, L., (2018):
Chemicals in European waters : knowledge developments
EEA Report 18/2018
Office for Official Publications of the European Communities, Luxembourg, 76 pp.
Volltext (URL)
2017 (11)
- Altenburger, R., Gündel, U., Rotter, S., Vogs, C., Faust, M., Backhaus, T., (2017):
Establishment of a concept for comparative risk assessment of plant protection products with special focus on the risks to the environment. Project No. (FKZ) 3712 67 406. Report No. (UBA-FB) 002256/ENG
Texte Umweltbundesamt 47/2017
Umweltbundesamt, Dessau-Roßlau, 215 pp.
Volltext (URL) - Brack, W., Dulio, V., Ågerstrand, M., Allan, I., Altenburger, R., Brinkmann, M., Bunke, D., Burgess, R.M., Cousins, I., Escher, B.I., Hernández, F.J., Hewitt, L.M., Hilscherová, K., Hollender, J., Hollert, H., Kase, R., Klauer, B., Lindim, C., López Herráez, D., Miège, C., Munthe, J., O'Toole, S., Posthuma, L., Rüdel, H., Schäfer, R.B., Sengl, M., Smedes, F., van de Meent, D., van den Brink, P., van Gils, J., van Wezel, A.P., Dick Vethaak, A., Vermeirssen, E., von der Ohe, P.C., Vrana, B., (2017):
Towards the review of the European Union Water Framework Directive: Recommendations for more efficient assessment and management of chemical contamination in European surface water resources
Sci. Total Environ. 576 , 720 - 737
Volltext (DOI) - Crawford, S.E., Brüll, C., Aumeier, B., Brinkmann, M., Classen, E., Esser, V., Ganal, C., Kaip, E., Häussling, R., Lehmkuhl, F., Letmathe, P., Müller, A.-K., Rabinovitch, I., Reicherter, K., Schwarzbauer, J., Schmitt, M., Stauch, G., Wessling, M., Yüce, S., Hecker, M., Kidd, K.A., Altenburger, R., Brack, W., Schüttrumpf, H., Hollert, H., (2017):
Project house water: a novel interdisciplinary framework to assess the environmental and socioeconomic consequences of flood-related impacts
Environ. Sci. Eur. 29 , art. 23
Volltext (DOI) - Escher, B.I., Hackermüller, J., Polte, T., Scholz, S., Aigner, A., Altenburger, R., Böhme, A., Bopp, S.K., Brack, W., Busch, W., Chadeau-Hyam, M., Covaci, A., Eisenträger, A., Galligan, J.J., Garcia-Reyero, N., Hartung, T., Hein, M., Herberth, G., Jahnke, A., Kleinjans, J., Klüver, N., Krauss, M., Lamoree, M., Lehmann, I., Luckenbach, T., Miller, G.W., Müller, A., Phillips, D.H., Reemtsma, T., Rolle-Kampczyk, U., Schüürmann, G., Schwikowski, B., Tan, Y.-M., Trump, S., Walter-Rohde, S., Wambaugh, J.F., (2017):
From the exposome to mechanistic understanding of chemical-induced adverse effects
Environ. Int. 99 , 97 - 106
Volltext (DOI) - Jakob, L., Bedulina, D.S., Axenov-Gribanov, D.V., Ginzburg, M., Shatilina, Z.M., Lubyaga, Y.A., Madyarova, E.V., Gurkov, A.N., Timofeyev, M.A., Portner, H.-O., Sartoris, F.J., Altenburger, R., Luckenbach, T., (2017):
Uptake kinetics and subcellular compartmentalization explain lethal but not sublethal effects of cadmium in two closely related amphipod species
Environ. Sci. Technol. 51 (12), 7208 - 7218
Volltext (DOI) - Kühnert, A., Vogs, C., Seiwert, B., Aulhorn, S., Altenburger, R., Hollert, H., Küster, E., Busch, W., (2017):
Biotransformation in the zebrafish embryo – temporal gene transcription changes of cytochrome P450 enzymes and internal exposure dynamics of the AhR binding xenobiotic benz[a]anthracene
Environ. Pollut. 230 , 1 - 11
Volltext (DOI) - Munthe, J., Brorström-Lundén, E., Rahmberg, M., Posthuma, L., Altenburger, R., Brack, W., Bunke, D., Engelen, G., Gawlik, B.M., van Gils, J., López Herráez, D., Rydberg, T., Slobodnik, J., van Wezel, A., (2017):
An expanded conceptual framework for solution-focused management of chemical pollution in European waters
Environ. Sci. Eur. 29 , art. 13
Volltext (DOI) - Neale, P.A., Altenburger, R., Aït-Aïssa, S., Brion, F., Busch, W., De Aragão Umbuzeiro, G., Denison, M.S., Du Pasquier, D., Hilscherová, K., Hollert, H., Morales, D.A., Novák, J., Schlichting, R., Seiler, T.-B., Serra, H., Shao, Y., Tindall, A.J., Tollefsen, K.E., Williams, T.D., Escher, B.I., (2017):
Development of a bioanalytical test battery for water quality monitoring: Fingerprinting identified micropollutants and their contribution to effects in surface water
Water Res. 123 , 734 - 750
Volltext (DOI) - Neale, P.A., Munz, N.A., Aїt-Aїssa, S., Altenburger, R., Brion, F., Busch, W., Escher, B.I., Hilscherová, K., Kienle, C., Novák, J., Seiler, T.-B., Shao, Y., Stamm, C., Hollender, J., (2017):
Integrating chemical analysis and bioanalysis to evaluate the contribution of wastewater effluent on the micropollutant burden in small streams
Sci. Total Environ. 576 , 785 - 795
Volltext (DOI) - Schmidt, S., Busch, W., Altenburger, R., (2017):
Biotestverfahren zur Abschätzung von Wirkpotenzialen in der aquatischen Umwelt : Vorschlag einer modularen Biotestbatterie für das aquatische Umweltmonitoring als Ergebnis einer systematischen Literaturrecherche und Bewertung
LUBW Landesanstalt für Umwelt Baden-Württemberg, Karlsruhe, 98 S. - Schüttler, A., Reiche, K., Altenburger, R., Busch, W., (2017):
The transcriptome of the zebrafish embryo after chemical exposure: a meta-analysis
Toxicol. Sci. 157 (2), 291 - 304
Volltext (DOI)
2016 (7)
- Busch, W., Schmidt, S., Kühne, R., Schulze, T., Krauss, M., Altenburger, R., (2016):
Micropollutants in European rivers: A mode of action survey to support the development of effect-based tools for water monitoring
Environ. Toxicol. Chem. 35 (8), 1887 - 1899
Volltext (DOI) - Faria, M., Pavlichenko, V.V., Burkhardt-Medicke, K., Soares, A.M.V.M., Altenburger, R., Barata, C., Luckenbach, T., (2016):
Corrigendum to "Use of a combined effect model approach for discriminating between ABCB1- and ABCC1-type efflux activities in native bivalve gill tissue" [Toxicol. Appl. Pharmacol. (2016) 56–67]
Toxicol. Appl. Pharmacol. 303 , 110
Volltext (DOI) - Faria, M., Pavlichenko, V.V., Burkhardt-Medicke, K., Soares, A.M.V.M., Altenburger, R., Barata, C., Luckenbach, T., (2016):
Use of a combined effect model approach for discriminating between ABCB1- and ABCC1-type efflux activities in native bivalve gill tissue
Toxicol. Appl. Pharmacol. 297 , 56 - 67
Volltext (DOI) - Klüver, N., Vogs, C., Altenburger, R., Escher, B.I., Scholz, S., (2016):
Development of a general baseline toxicity QSAR model for the fish embryo acute toxicity test
Chemosphere 164 , 164 - 173
Volltext (DOI) - Rose, S., Altenburger, R., Sturm, A., (2016):
Mixture toxicity effects of sea louse control agents in Daphnia magna
Chemosphere 144 , 599 - 606
Volltext (DOI) - Schmidt, S., Busch, W., Altenburger, R., Küster, E., (2016):
Mixture toxicity of water contaminants-effect analysis using the zebrafish embryo assay (Danio rerio)
Chemosphere 152 , 503 - 512
Volltext (DOI) - Vogs, C., Altenburger, R., (2016):
Time-dependent effects in algae for chemicals with different adverse outcome pathways: a novel approach
Environ. Sci. Technol. 50 (14), 7770 - 7780
Volltext (DOI)
2015 (9)
- Altenburger, R., Ait-Aissa, S., Antczak, P., Backhaus, T., Barceló, D., Seiler, T.-B., Brion, F., Busch, W., Chipman, K., López de Alda, M., De Aragão Umbuzeiro, G., Escher, B.I., Falciani, F., Faust, M., Focks, A., Hilscherova, K., Hollender, J., Hollert, H., Jäger, F., Jahnke, A., Kortenkamp, A., Krauss, M., Lemkine, G.F., Munthe, J., Neumann, S., Schymanski, E.L., Scrimshaw, M., Segner, H., Slobodnik, J., Smedes, F., Kughathas, S., Teodorovic, I., Tindall, A.J., Tollefsen, K.E., Walz, K.-H., Williams, T.D., van den Brink, P.J., van Gils, J., Vrana, B., Zhang, X., Brack, W., (2015):
Future water quality monitoring — Adapting tools to deal with mixtures of pollutants in water resource management
Sci. Total Environ. 512-513 , 540 - 551
Volltext (DOI) - Brack, W., Altenburger, R., Schüürmann, G., Krauss, M., López Herráez, D., van Gils, J., Slobodnik, J., Munthe, J., Gawlik, B.M., van Wezel, A., Schriks, M., Hollender, J., Tollefsen, K.E., Mekenyan, O., Dimitrov, S., Bunke, D., Cousins, I., Posthuma, L., van den Brink, P.J., López de Alda, M., Barceló, D., Faust, M., Kortenkamp, A., Scrimshaw, M., Ignatova, S.N., Engelen, G., Massmann, G., Lemkine, G., Teodorovic, I., Walz, K.-H., Dulio, V., Jonker, M.T.O., Jäger, F., Chipman, K., Falciani, F., Liska, I., Rooke, D., Zhang, X., Hollert, H., Vrana, B., Hilscherova, K., Kramer, K., Neumann, S., Hammerbacher, R., Backhaus, T., Mack, J., Segner, H., Escher, B., De Aragão Umbuzeiro, G., (2015):
The SOLUTIONS project: challenges and responses for present and future emerging pollutants in land and water resources management
Sci. Total Environ. 503-504 , 22 - 31
Volltext (DOI) - Fetter, E., Smetanová, S., Baldauf, L., Lidzba, A., Altenburger, R., Schüttler, A., Scholz, S., (2015):
Identification and characterization of androgen-responsive genes in zebrafish embryos
Environ. Sci. Technol. 49 (19), 11789 - 11798
Volltext (DOI) - Luckenbach, T., Küster, E., Busch, W., Scholz, S., Altenburger, R., (2015):
What determines chemical uptake by the zebrafish embryo model?
Toxicol. Lett. 238 (2, Suppl.), S54
Volltext (DOI) - Massei, R., Vogs, C., Renner, P., Altenburger, R., Scholz, S., (2015):
Differential sensitivity in embryonic stages of the zebrafish (Danio rerio): The role of toxicokinetics for stage-specific susceptibility for azinphos-methyl lethal effects
Aquat. Toxicol. 166 , 36 - 41
Volltext (DOI) - Riedl, J., Schreiber, R., Otto, M., Heilmeier, H., Altenburger, R., Schmitt-Jansen, M., (2015):
Metabolic effect level index links multivariate metabolic fingerprints to ecotoxicological effect assessment
Environ. Sci. Technol. 49 (13), 8096 - 8104
Volltext (DOI) - Rotter, S., Gunold, R., Mothes, S., Paschke, A., Brack, W., Altenburger, R., Schmitt-Jansen, M., (2015):
Pollution-induced community tolerance to diagnose hazardous chemicals in multiple contaminated aquatic systems
Environ. Sci. Technol. 49 (16), 10048 - 10056
Volltext (DOI) - Smetanová, S., Riedl, J., Zitzkat, D.P., Altenburger, R., Busch, W., (2015):
High-throughput concentration–response analysis for omics datasets
Environ. Toxicol. Chem. 34 (9), 2167 - 2180
Volltext (DOI) - Vogs, C., Kühnert, A., Hug, C., Küster, E., Altenburger, R., (2015):
A toxicokinetic study of specifically acting and reactive organic chemicals for the prediction of internal effect concentrations in Scenedesmus vacuolatus
Environ. Toxicol. Chem. 34 (1), 100 - 111
Volltext (DOI)
2014 (5)
- Altenburger, R., Arrhenius, A., Backhaus, T., Coors, A., Faust, M., Zitzkat, D.P., (2014):
Ecotoxicological combined effects from chemical mixtures. Part 1: Relevance and adequate consideration in environmental risk assessment of plant protection products and biocides
Texte Umweltbundesamt 92/2013
Umweltbundesamt, Dessau-Roßlau, 203 pp.
Volltext (URL) - Campos, B., Altenburger, R., Gómez, C., Lacorte, S., Piña, B., Barata, C., Luckenbach, T., (2014):
First evidence for toxic defense based on the multixenobiotic resistance (MXR) mechanism in Daphnia magna
Aquat. Toxicol. 148 , 139 - 151
Volltext (DOI) - Escher, B.I., Allinson, M., Altenburger, R., Bain, P.A., Balaguer, P., Busch, W., Crago, J., Denslow, N.D., Dopp, E., Hilscherova, K., Humpage, A.R., Kumar, A., Grimaldi, M., Jayasinghe, B.S., Jarosova, B., Jia, A., Makarov, S., Maruya, K.A., Medvedev, A., Mehinto, A.C., Mendez, J.E., Poulsen, A., Prochazka, E., Richard, J., Schifferli, A., Schlenk, D., Scholz, S., Shiraishi, F., Snyder, S., Su, G., Tang, J.Y.M., van der Burg, B., van der Linden, S.C., Werner, I., Westerheide, S.D., Wong, C.K.C., Yang, M., Yeung, B.H.Y., Zhang, X., Leusch, F.D.L., (2014):
Benchmarking organic micropollutants in wastewater, recycled water and drinking water with in vitro bioassays
Environ. Sci. Technol. 48 (3), 1940 - 1956
Volltext (DOI) - Faust, M., Vogs, C., Rotter, S., Wöltjen, J., Höllrigl-Rosta, A., Backhaus, T., Altenburger, R., (2014):
Comparative assessment of plant protection products: how many cases will regulatory authorities have to answer?
Environ. Sci. Eur. 26 , art. 11
Volltext (DOI) - Pannier, A., Soltmann, U., Soltmann, B., Altenburger, R., Schmitt-Jansen, M., (2014):
Alginate/silica hybrid materials for immobilization of green microalgae Chlorella vulgaris for cell-based sensor arrays
J. Mat. Chem. B 45 (2), 7896 - 7909
Volltext (DOI)
2013 (7)
- Altenburger, R., Backhaus, T., Boedeker, W., Faust, M., Scholze, M., (2013):
Simplifying complexity : mixture toxicity assessment in the last 20 years
Environ. Toxicol. Chem. 32 (8), 1685 - 1687
Volltext (DOI) - Backhaus, T., Altenburger, R., Faust, M., Frein, D., Frische, T., Johansson, P., Kehrer, A., Porsbring, T., (2013):
Proposal for environmental mixture risk assessment in the context of the biocidal product authorization in the EU
Environ. Sci. Eur. 25 , art. 4
Volltext (DOI) - Escher, B.I., van Daele, C., Dutt, M., Tang, J.Y.M., Altenburger, R., (2013):
Most oxidative stress response in water samples comes from unknown chemicals: the need for effect-based water quality trigger values
Environ. Sci. Technol. 47 (13), 7002 - 7011
Volltext (DOI) - Kühnert, A., Vogs, C., Altenburger, R., Küster, E., (2013):
The internal concentration of organic substances in fish embryos - a toxicokinetic approach
Environ. Toxicol. Chem. 32 (8), 1819 - 1827
Volltext (DOI) - Riedl, J., Rotter, S., Faetsch, S., Schmitt-Jansen, M., Altenburger, R., (2013):
Proposal for applying a component-based mixture approach for ecotoxicological assessment of fracturing fluids
Environ. Earth Sci. 70 (8), 3907 - 3920
Volltext (DOI) - Rotter, S., Heilmeier, H., Altenburger, R., Schmitt-Jansen, M., (2013):
Multiple stressors in periphyton – comparison of observed and predicted tolerance responses to high ionic loads and herbicide exposure
J. Appl. Ecol. 50 (6), 1459 - 1468
Volltext (DOI) - Vogs, C., Bandow, N., Altenburger, R., (2013):
Effect propagation in a toxicokinetic/toxicodynamic model explains delayed effects on the growth of unicellular green algae Scenedesmus vacuolatus
Environ. Toxicol. Chem. 32 (5), 1161 - 1172
Volltext (DOI)
2012 (5)
- Altenburger, R., Scholz, S., Schmitt-Jansen, M., Busch, W., Escher, B.I., (2012):
Mixture toxicity revisited from a toxicogenomic perspective
Environ. Sci. Technol. 46 (5), 2508 - 2522
Volltext (DOI) - Frimmel, F.H., Ewers, U., Schmitt-Jansen, M., Gordalla, B., Altenburger, R., (2012):
Toxikologische Bewertung von Fracking-Fluiden
Wasser und Abfall 14 (6), 22 - 29 - Gündel, U., Kalkhof, S., Zitzkat, D.P., von Bergen, M., Altenburger, R., Küster, E., (2012):
Concentration-response concept in ecotoxicoproteomics: effects of different phenanthrene concentrations to the zebrafish (Danio rerio) embryo proteome
Ecotox. Environ. Safe. 76 (1), 11 - 22
Volltext (DOI) - Riedl, J., Kluender, C., Sans-Piché, F., Heilmeier, H., Altenburger, R., Schmitt-Jansen, M., (2012):
Spatial and temporal variation in metabolic fingerprints of field-growing Myriophyllum spicatum
Aquat. Bot. 102 , 34 - 43
Volltext (DOI) - van Dam, J.W., Negri, A.P., Mueller, J.F., Altenburger, R., Uthicke, S., (2012):
Additive pressures of elevated sea surface temperatures and herbicides on symbiont-bearing foraminifera
PLoS One 7 (3), e33900
Volltext (DOI)
2011 (7)
- Altenburger, R., (2011):
Understanding combined effects for metal co-exposure in ecotoxicology
In: Sigel, A., Sigel, H., Sigel, R.K.O., (eds.)
Metal ions in toxicology: effects, interactions, interdependencies
Metal Ions in Life Sciences 8
Royal Society of Chemistry (RSC), Cambridge, p. 1 - 26
Volltext (DOI) - Kortenkamp, A., Altenburger, R., (2011):
Toxicity from combined exposure to chemicals
In: van Gestel, C.A.M., Jonker, M.J., Kammenga, J.E., Laskowski, R., Svendsen, C., (eds.)
Mixture toxicity: linking approaches from ecotoxicology and human toxicology
CRC Press, Boca Raton, FL, p. 95 - 120 - Küster, A., Altenburger, R., (2011):
Characeen als Objekte ökotoxikologischer Untersuchungen
Ber. Bot. Arbeitsgem. Südwestdeutschland (Beiheft 3), 31 - 36 - Rotter, S., Sans-Piché, F., Streck, G., Altenburger, R., Schmitt-Jansen, M., (2011):
Active bio-monitoring of contamination in aquatic systems - an in situ translocation experiment applying the PICT concept
Aquat. Toxicol. 101 (1), 228 - 236
Volltext (DOI) - Schreiber, R., Gündel, U., Franz, S., Küster, A., Rechenberg, B., Altenburger, R., (2011):
Using the fish plasma model for comparative hazard identification for pharmaceuticals in the environment by extrapolation from human therapeutic data
Regul. Toxicol. Pharmacol. 61 (3), 261 - 275
Volltext (DOI) - Schreiber, R., Küster, A., Feiler, U., Grote, M., Altenburger, R., (2011):
A non-invasive observation parameter to complement sediment bioassays using Myriophyllum aquaticum
J. Soils Sediments 11 (8), 1419 - 1431
Volltext (DOI) - Siegert, F., Erdmann, F., Schwan, G., Scholz, S., Briel, D., Altenburger, R., Nieber, K., (2011):
Pharmacological and cytotoxic effects of new selective PDE10A ligands
Naunyn-Schmiedebergs Arch. Pharmacol. 383 (Suppl. 1), 21 - 21
Volltext (DOI)
2010 (10)
- Altenburger, R., Berns, A.E., Bittens, M., Brack, W., Burauel, P., Centler, F., Daus, B., Goss, K.-U., Harms, H., Kopinke, F.-D., Kühnel, D., Liess, M., Mackenzie, K., Miltner, A., Thullner, M., Wennrich, R., Wick, L.Y., (2010):
Chemicals in the environment (CITE). Report of the First Annual Conference of the Helmholtz research topic CITE
UWSF 22 (4), 502 - 506
Volltext (DOI) - Altenburger, R., Krüger, A., Eisenträger, A., (2010):
Proposing a pH stabilised nutrient medium for algal growth bioassays
Chemosphere 78 (7), 864 - 870
Volltext (DOI) - Bandow, N., Altenburger, R., Brack, W., (2010):
Application of nd-SPME to determine freely dissolved concentrations in the presence of green algae and algae-water partition coefficients
Chemosphere 79 (11), 1070 - 1076
Volltext (DOI) - Daus, B., Weiß, H., Altenburger, R., (2010):
Uptake and toxicity of hexafluoroarsenate in aquatic organisms
Chemosphere 78 (3), 307 - 312
Volltext (DOI) - Daus, B., Weiß, H., Wennrich, R., Altenburger, R., (2010):
Are fluorine containing arsenic species an environmental problem?
In: Jean, J.-S., Bundschuh, J., Bhattacharya, P., (eds.)
Arsenic in geosphere and human diseases; Arsenic 2010: Proceedings of the Third International Congress on Arsenic in the Environment
Taylor & Francis, London, p. 376 - 377 - Gündel, U., Kalkhof, S., von Bergen, M., Altenburger, R., Küster, E., (2010):
Concentration-response concept in ecotoxicoproteomics: an optimised design for the detection of robust chemical stress associated protein markers: Effects of different concentrations of phenanthren to the proteome of Danio rerio embryos
Comp. Biochem. Physiol. A-Mol. Integr. Physiol. 157 (Suppl. 1), S42 - S43
Volltext (DOI) - Hanisch, K., Küster, E., Altenburger, R., Gündel, U., (2010):
Proteomic signatures of the zebrafish (Danio rerio) embryo: sensitivity and specificity in toxicity assessment of chemicals
International Journal of Proteomics 2010 , Article ID 630134 - 13
Volltext (DOI) - Sans-Piché, F., Kluender, C., Altenburger, R., Schmitt-Jansen, M., (2010):
Anchoring metabolic changes to phenotypic effects in the chlorophyte Scenedesmus vacuolatus under chemical exposure
Mar. Environ. Res. 69 (Suppl. 1), 528 - 530
Volltext (DOI) - Scholz, S., Schirmer, K., Altenburger, R., (2010):
Pharmaceutical contaminants in urban water cycles - a discussion of novel concepts for environmental risk assessment
In: Fata-Kassinos, D., Bester, K., Kümmerer, K., (eds.)
Xenobiotics in the urban water cycle: mass flows, environmental processes and mitigation strategies
Environ. Pollut. 16
Springer, Heidelberg, p. 227 - 244
Volltext (DOI) - Schulze, T., Weiss, S., Schymanski, E., von der Ohe, P.C., Schmitt-Jansen, M., Altenburger, R., Streck, G., Brack, W., (2010):
Identification of a phytotoxic photo-transformation product of diclofenac using effect-directed analysis
Environ. Pollut. 158 (5), 1461 - 1466
Volltext (DOI)
2009 (8)
- Altenburger, R., Greco, W.R., (2009):
Extrapolation concepts for dealing with multiple contamination in environmental risk assessment
Integr. Environ. Assess. Manag. 5 (1), 62 - 68
Volltext (DOI) - Altenburger, R., Gündel, U., Ali-Aycheh, M., Hanisch, K., Küster, A., Rechenberg, B., Schreiber, R., (2009):
Models for extrapolation of long-term effects of pharmaceuticals in the environment using therapeutic information
Toxicol. Lett. 189 (Suppl. 1), S191 - S192
Volltext (DOI) - Bandow, N., Altenburger, R., Lübcke-von Varel, U., Paschke, A., Streck, G., Brack, W., (2009):
Partitioning-based dosing: an approach to include bioavailability in the effect-directed analysis of contaminated sediment samples
Environ. Sci. Technol. 43 (10), 3891 - 3896
Volltext (DOI) - Bandow, N., Altenburger, R., Streck, G., Brack, W., (2009):
Effect-directed analysis of contaminated sediments with partition-based dosing using green algae cell multiplication inhibition
Environ. Sci. Technol. 43 (19), 7343 - 7349
Volltext (DOI) - Kluender, C., Sans-Piché, F., Riedl, J., Altenburger, R., Härtig, C., Laue, G., Schmitt-Jansen, M., (2009):
A metabolomics approach to assessing phytotoxic effects on the green alga Scenedesmus vacuolatus
Metabolomics 5 (1), 59 - 71
Volltext (DOI) - Rodil, R., Moeder, M., Altenburger, R., Schmitt-Jansen, M., (2009):
Photostability and phytotoxicity of selected sunscreen agents and their degradation mixtures in water
Anal. Bioanal. Chem. 395 (5), 1513 - 1524
Volltext (DOI) - Schreiber, R., Altenburger, R., Paschke, A., Schüürmann, G., Küster, E., (2009):
A novel in vitro system for the determination of bioconcentration factors and the internal dose in zebrafish (Danio rerio) eggs
Chemosphere 77 (7), 928 - 933
Volltext (DOI) - Schwab, K., Altenburger, R., Lübcke-von Varel, U., Streck, G., Brack, W., (2009):
Effect-directed analysis of sediment-associated algal toxicants at selected hot spots in the river Elbe basin with a special focus on bioaccessibility
Environ. Toxicol. Chem. 28 (7), 1506 - 1517
Volltext (DOI)
2008 (9)
- Altenburger, R., Schmitt-Jansen, M., Riedl, J., (2008):
Bioassays with unicellular algae: deviations from exponential growth and its implications for toxicity test results
J. Environ. Qual. 37 (1), 16 - 21
Volltext (DOI) - Franz, S., Altenburger, R., Heilmeier, H., Schmitt-Jansen, M., (2008):
What contributes to the sensitivity of microalgae to triclosan?
Aquat. Toxicol. 90 (2), 102 - 108
Volltext (DOI) - Küster, E., Altenburger, R., (2008):
Oxygen decline in biotesting of environmental samples - Is there a need for consideration in the acute zebrafish embryo assay?
Environ.Toxicol. 23 (6), 745 - 750
Volltext (DOI) - Luckenbach, T., Altenburger, R., Epel, D., (2008):
Teasing apart activities of different types of ABC efflux pumps in bivalve gills using the concepts of independent action and concentration addition
Mar. Environ. Res. 66 (1), 75 - 76
Volltext (DOI) - McClellan, K., Altenburger, R., Schmitt-Jansen, M., (2008):
Pollution-induced community tolerance as a measure of species interaction in toxicity assessment
J. Appl. Ecol. 45 (5), 1514 - 1522
Volltext (DOI) - Posthuma, L., Richards, S.M., de Zwart, D., Dyer, S.D., Sibley, P.K., Hickey, C.W., Altenburger, R., (2008):
Mixture extrapolation approaches
In: Solomon, K.R., Brock, T.C.M., de Zwart, D., Dyer, S.D., Posthuma, L., Richards, S.M., Sanderson, H., Sibley, P.K., van den Brink, P.J., (eds.)
Extrapolation practice for ecotoxicological effect characterization of chemicals
CRC Press, Boca Raton, FL, p. 135 - 185 - Schmitt-Jansen, M., Altenburger, R., (2008):
Community-level microalgal toxicity assessment by multiwavelength-excitation PAM fluorometry
Aquat. Toxicol. 86 (1), 49 - 58
Volltext (DOI) - Schmitt-Jansen, M., Veit, U., Dudel, G., Altenburger, R., (2008):
An ecological perspective in aquatic ecotoxicology: approaches and challenges
Basic Appl. Ecol. 9 (4), 337 - 345
Volltext (DOI) - Schreiber, R., Altenburger, R., Paschke, A., Küster, E., (2008):
How to deal with lipophilic and volatile organic substances in microtiter plate assays
Environ. Toxicol. Chem. 27 (8), 1676 - 1682
Volltext (DOI)
2007 (11)
- Adler, N.E., Schmitt-Jansen, M., Altenburger, R., (2007):
Flow cytometry as a tool to study phytotoxic modes of action
Environ. Toxicol. Chem. 26 (2), 297 - 306
Volltext (DOI) - Bakker, J.F., Belzunce-Segarra, M.J., Castro, R., van de Heuvel-Greve, M., Klamer, H.J.C., Brack, W., Altenburger, R., Poulsen, V., Thomas, K.V., Leonards, P.E.G., (2007):
Effect directed analysis and toxicity identification evaluation
In: Barceló, D., Petrovic, M., (eds.)
Sediment quality and impact assessment of pollutants
Sustainable Management of Sediment Resources Vol. 1
Elsevier, Amsterdam, p. 163 - 214
Volltext (DOI) - Gündel, U., Benndorf, D., von Bergen, M., Altenburger, R., Küster, E., (2007):
Vitellogenin cleavage products as indicators for toxic stress in zebra fish embryos: a proteomic approach
Proteomics 7 (24), 4541 - 4554
Volltext (DOI) - Küster, A., Altenburger, R., (2007):
Development and validation of a new fluorescence-based bioassay for aquatic macrophyte species
Chemosphere 67 (1), 194 - 201
Volltext (DOI) - Küster, A., Pohl, K., Altenburger, R., (2007):
A fluorescence-based bioassay for aquatic macrophytes and its suitability for effect analysis of non-photosystem II inhibitors
Environ. Sci. Pollut. Res. 14 (6), 377 - 383
Volltext (DOI) - Küster, E., Altenburger, R., (2007):
Suborganismic and organismic effects of aldicarb and its metabolite aldicarb-sulfoxide to the zebrafish embryo (Danio rerio)
Chemosphere 68 (4), 751 - 760
Volltext (DOI) - Pohl, K., Altenburger, R., Küster, A., (2007):
Entwicklung und Etablierung eines Kurzzeit-Biotestsystems für aquatische Makrophyten
Erweiterte Zusammenfassungen der Jahrestagung 2006 der Deutschen Gesellschaft für Limnologie (DGL) und der deutschen und österreichischen Sektion der Societas Internationalis Limnologiae (SIL). Dresden, 25. - 29.09.2006
Deutsche Gesellschaft für Limnologie, Werder, S. 368 - 372 - Riedl, J., Altenburger, R., (2007):
Physicochemical substance properties as indicators for unreliable exposure in microplate-based bioassays
Chemosphere 67 (11), 2210 - 2220
Volltext (DOI) - Schmitt-Jansen, M., Altenburger, R., (2007):
The use of pulse-amplitude modulated (PAM) fluorescence-based methods to evaluate effects of herbicides in microalgal systems of different complexity
Toxicol. Environ. Chem. 89 (4), 651 - 667
Volltext (DOI) - Schmitt-Jansen, M., Bartels, P., Adler, N., Altenburger, R., (2007):
Phytotoxicity assessment of diclofenac and its phototransformation products
Anal. Bioanal. Chem. 387 (4), 1389 - 1396
Volltext (DOI) - Tammer, B., Lehmann, I., Nieber, K., Altenburger, R., (2007):
Combined effects of mycotoxin mixtures on human T cell function
Toxicol. Lett. 170 (2), 124 - 133
Volltext (DOI)
2006 (2)
- Altenburger, R., Brack, W., Greco, W.R., Grote, M., Jung, K., Ovari, A., Riedl, J., Schwab, K., Küster, E., (2006):
On the mode of action of N-phenyl-2-naphthylamine in plants
Environ. Sci. Technol. 40 (19), 6163 - 6169
Volltext (DOI) - Küster, E., Altenburger, R., (2006):
Comparison of cholin- and carboxylesterase enzyme inhibition and visible effects in the zebra fish embryo bioassay under short-term paraoxon-methyl exposure
Biomarkers 11 (4), 341 - 354
Volltext (DOI)
2005 (14)
- Altenburger, R., Schmitt, H., Schüürmann, G., (2005):
Algal toxicity of nitrobenzenes: combined effect analysis as a pharmacological probe for similar modes of interaction
Environ. Toxicol. Chem. 24 (2), 324 - 333
Volltext (DOI) - Grote, M., Altenburger, R., Brack, W., Moschütz, S., Mothes, S., Michael, C., Narten, G.-B., Paschke, A., Schirmer, K., Walter, H.A., Wennrich, R., Wenzel, K.-D., Schüürmann, G., (2005):
Ecotoxicological profiling of transect river Elbe sediments
Acta Hydrochim. Hydrobiol. 33 (5), 555 - 569
Volltext (DOI) - Grote, M., Brack, W., Altenburger, R., (2005):
Identification of toxicants from marine sediment using effect-directed analysis
Environ.Toxicol. 20 (5), 475 - 486
Volltext (DOI) - Grote, M., Brack, W., Walter, H.A., Altenburger, R., (2005):
Confirmation of cause-effect relationships using effect-directed analysis for complex environmental samples
Environ. Toxicol. Chem. 24 (6), 1420 - 1427
Volltext (DOI) - Grote, M., Brack, W., Walter, H.A., Altenburger, R., (2005):
Light as a confounding factor for toxicity assessment of complex contaminated sediments
Environ. Toxicol. Chem. 24 (12), 3143 - 3152
Volltext (DOI) - Grote, M., Schüürmann, G., Altenburger, R., (2005):
Modeling photoinduced algal toxicity of polycyclic aromatic hydrocarbons
Environ. Sci. Technol. 39 (11), 4141 - 4149
Volltext (DOI) - Küster, E., Dorusch, F., Altenburger, R., (2005):
Effects of hydrogen sulfide to Vibrio fischeri, Scenedesmus vacuolatus, and Daphnia magna
Environ. Toxicol. Chem. 24 (10), 2621 - 2629
Volltext (DOI) - Küster, E., Dorusch, F., Altenburger, R., (2005):
Toxizität von Schwefelwasserstoff (H2S) auf die Biotestorganismen Vibrio fischeri und Daphnia magna
Tagungsbericht 2004 der Deutschen Gesellschaft für Limnologie e.V. (DGL) und der Deutschsprachigen Sektion der Societas Internationalis Limnologiae (SIL). Potsdam, 20. - 24.09.2004
Deutsche Gesellschaft für Limnologie, Berlin, S. 561 - 565 - Olajire, A.A., Altenburger, R., Küster, E., Brack, W., (2005):
Chemical and ecotoxicological assessment of polycyclic aromatic hydrocarbon-contaminated sediments of the Niger Delta, Southern Nigeria
Sci. Total Environ. 340 (1-3), 123 - 136
Volltext (DOI) - Schmitt-Jansen, M., Altenburger, R., (2005):
Toxic effects of isoproturon on periphyton communities - a microcosm study
Estuar. Coast. Shelf Sci. 62 (3), 539 - 545
Volltext (DOI) - Schmitt-Jansen, M., Altenburger, R., (2005):
Predicting and observing responses of algal communities to photosystem II-herbicide exposure using pollution-induced community tolerance and species-sensitivity distributions
Environ. Toxicol. Chem. 24 (2), 304 - 312
Volltext (DOI) - Schmitt-Jansen, M., Altenburger, R., (2005):
Lassen sich Ergebnisse aus ökotoxikologischen Einzelartentests auf aquatische Lebensgemeinschaften extrapolieren?
Tagungsbericht 2004 der Deutschen Gesellschaft für Limnologie e.V. (DGL) und der Deutschsprachigen Sektion der Societas Internationalis Limnologiae (SIL). Potsdam, 20. - 24.09.2004
Deutsche Gesellschaft für Limnologie, Berlin, S. 556 - 560 - von der Ohe, P.C., Kühne, R., Ebert, R.U., Altenburger, R., Liess, M., Schüürmann, G., (2005):
Structural alerts - a new classification model to discriminate excess toxicity from narcotic effect levels of organic compounds in the acute daphnid assay
Chem. Res. Toxicol. 18 (3), 536 - 555
Volltext (DOI) - Wollin, K.M., Altenburger, R., Altmayer, M., Dieter, H.H., Moll, B., Six, E., von der Trenck, K.T., (2005):
(ECO)toxicological insignificance thresholds for risk assessment of polluted groundwater
Naunyn-Schmiedebergs Arch. Pharmacol. 371 (Suppl. 1), R133 - R134
2004 (9)
- Altenburger, R., Walter, H., Grote, M., (2004):
What contributes to the combined effect of a complex mixture?
Environ. Sci. Technol. 38 (23), 6353 - 6362
Volltext (DOI) - Bopp, S., Schirmer, M., Russold, S., Altenburger, R., Schirmer, K., (2004):
Combined chemical/biological monitoring as part of assessing natural attenuation at a BTEX-contaminated megasite
In: Magar, V.S., Kelley, M.E., (eds.)
7th International In Situ and On-Site Bioremediation Symposium, Orlando/USA, 2.-5.6.2003
Battelle Press, Columbus, OH, p. Paper H32 - Grote, M., Altenburger, R., Brack, W., Möckel, C., Moschütz, S., Mothes, S., Michael, C., Narten, G.-B., Paschke, A., Schirmer, K., Walter, H., Wennrich, R., Wenzel, K.-D., Schüürmann, G., (2004):
Identifizierung und Analyse des ökotoxischen Potentials von Flusssedimenten als Folge der durch Hochwasser mobilisierten Kontamination
In: Geller, W., Ockenfeld, K., Böhme, M., Knöchel, A., (Hrsg.)
Schadstoffbelastung nach dem Elbe-Hochwasser 2002. Endbericht des Ad-hoc-Verbundprojekts
UFZ Leipzig-Halle GmbH, Magdeburg, S. 314 - 329 - Grote, M., Walter, H., Altenburger, R., (2004):
Toxizitätsuntersuchungen von Elbsedimenten in Kontakttesten mit Lemna minor und Danio rerio
Statusseminar Sedimentskontakttests : 24./25. März 2004 in Koblenz
Veranstaltungen / BfG 5/2004
Bundesanstalt für Gewässerkunde, Koblenz, S. 25 - 35 - Krumm, B., Altenburger, R., Nieber, K., Lehmann, I., (2004):
Low concentration of mycotoxins with weak effects as single compounds mediate strong inhibition of IFN-gamma release when exposed together
Immunobiology 209 (4-6), 470
Volltext (DOI) - Küster, E., Dorusch, F., Altenburger, R., (2004):
Ökotoxikologische Verfahren der Wirkungsanalyse für das Management von Grundwasser-Kontaminationen: Fallbeispiel quartärer Grundwasserleiter in Bitterfeld-Süd
In: Weiß, H., Teutsch, G., Daus, B., (Hrsg.)
SAFIRA (Sanierungsforschung in regional kontaminierten Aquiferen)
UFZ-Bericht 13/2004
UFZ Leipzig-Halle GmbH, Leipzig, S. 287 - 316 - Küster, E., Dorusch, F., Vogt, C., Weiß, H., Altenburger, R., (2004):
On line biomonitors used as a tool for toxicity reduction evaluation of in situ groundwater remediation techniques
Biosens. Bioelectron. 19 (12), 1711 - 1722
Volltext (DOI) - Schmitt-Jansen, M., Küster, A., Altenburger, R., (2004):
Untersuchung schadstofftoleranter Aufwuchsgemeinschaften als ein Instrument zur Bewertung von Schadstoffen in Gewässern
Tagungsbericht 2002 der Deutschen Gesellschaft für Limnologie (DGL) und der deutschen und österreichischen Sektion der Societas Internationionalis Limnologiae (SIL). Band II, Braunschweig, 30.9.-4.10.2002
Deutsche Gesellschaft für Limnologie, Werder, p. 621 - 626 - Schmitt-Jansen, M., Reiners, S., Altenburger, R., (2004):
Biozönotische Testverfahren (PICT-Konzept). Analyse von Schadstoff-induzierten Effekten in Gewässern mit autotrophen Aufwuchszönosen
UWSF 16 (2), 85 - 91
Volltext (DOI)
2003 (12)
- Altenburger, R., Brack, W., Grote, M., Moschütz, S., Paschke, A., Schirmer, K., Walter, H., Wenzel, K., Schüürmann, G., (2003):
Identifizierung und Analyse des ökotoxikologischen Potentials von Flußsedimenten als Folge der durch Hochwasser mobilisierten Kontaminationen
Schadstoffbelastung im Mulde- und Elbe-Einzugsgebiet nach dem Augusthochwasser 2002,
Ergebnisse und Forschungsbedarf, Tagungsband. Statusseminar des BMBF-Ad-hoc-Verbundprojektes, Freiberg, 27.-29. August 2003
UFZ Leipzig-Halle GmbH, Magdeburg, p. 9 - 12 - Altenburger, R., Nendza, M., Schüürmann, G., (2003):
Mixture toxicity and its modeling by quantitative structure-activity relationships
Environ. Toxicol. Chem. 22 (8), 1900 - 1915
Volltext (DOI) - Altenburger, R., Schmitt-Jansen, M., (2003):
Predicting toxic effects of contaminants in ecosystems using single species investigations
In: Breure, A.M., Markert, B.A., Zechmeister, H.G., (eds.)
Bioindicators & biomonitors. Principles, concepts and applications
Trace Metals and other Contaminants in the Environment 6
Elsevier, Amsterdam, p. 153 - 198
Volltext (DOI) - Altenburger, R., Segner, H., van der Oost, R., (2003):
Biomarkers and PAHs - prospects for the assessment of exposure and effects in aquatic systems
In: Douben, P.E.T., (ed.)
PAHs: an ecotoxicological perspective
Ecological and Environmental Toxicology Series
Wiley, Chichester, p. 297 - 328 - Backhaus, T., Altenburger, R., Arrhenius, A., Blanck, H., Faust, M., Finizio, A., Gramatica, P., Grote, M., Junghans, M., Meyer, W., Pavan, M., Porsbring, T., Scholze, M., Todeschini, R., Vighi, M., Walter, H., Grimme, L.H., (2003):
The BEAM-project: prediction and assessment of mixture toxicities in the aquatic environment
Cont. Shelf Res 23 (17-19), 1757 - 1769
Volltext (DOI) - Brack, W., Altenburger, R., Küster, E., Meissner, B., Wenzel, K.-D., Schüürmann, G., (2003):
Identification of toxic products of anthracene photomodification in simulated sunlight
Environ. Toxicol. Chem. 22 (10), 2228 - 2237
Volltext (DOI) - Faust, M., Altenburger, R., Backhaus, T., Blanck, H., Boedeker, W., Gramatica, P., Hamer, V., Scholze, M., Vighi, M., Grimme, L.H., (2003):
Joint algal toxicity of 16 dissimilarly acting chemicals is predictable by the concept of independent action
Aquat. Toxicol. 63 (1), 43 - 63
Volltext (DOI) - Küster, E., Dorusch, F., Meißner, B., Weiß, H., Schüürmann, G., Altenburger, R., (2003):
Toxizitätsreduktion durch (Grundwasser-) Sanierung? Erfolgskontrolle von In-situ-Grundwasser- Sanierungsverfahren mithilfe von kontinuierlichen und diskontinuierlichen Biotests
Grundwasser 8 (1), 32 - 40
Volltext (DOI) - Küster, E., Dorusch, F., Weiß, H., Altenburger, R., (2003):
Controlling (groundwater-) remediation success via on line biomonitoring or how toxic is remediated groundwater?
ConSoil 2003 : proceedings of the 8th International FZK/TNO Conference on Contaminated Soil, ICC Gent, Belgium, 12 - 16 May 2003
F&U confirm, Leipzig, p. 3305 - 3314 - Küster, E., Dorusch, F., Weiß, H., Schüürmann, G., Altenburger, R., (2003):
Beurteilung der Entgiftung von Grundwasser durch Sanierungsverfahren mittels kontinuierlicher biologischer Überwachung
In: Foth, H., (Hrsg.)
Risk assessment and management of large contamination sites. Gefahrenabschätzung und Handhabung großflächiger Kontaminationen. Proceedingsband zum Kongress an der Martin-Luther-Universität Halle-Wittenberg, 22. - 24. Februar 2002
S. 41 - 45 - Schirmer, K., Altenburger, R., Bopp, S., Weiß, H., (2003):
Toxikologische Überwachung beim Einsatz von "Natural Attenuation" als Sanierungsoption
In: Foth, H., (Hrsg.)
Risk assessment and management of large contamination sites. Gefahrenabschätzung und Handhabung großflächiger Kontaminationen. Proceedingsband zum Kongress an der Martin-Luther-Universität Halle-Wittenberg, 22. - 24. Februar 2002
S. 33 - 36 - Vighi, M., Altenburger, R., Arrhenius, A., Backhaus, T., Bödeker, W., Blanck, H., Consolaro, F., Faust, M., Finizio, A., Froehner, K., Gramatica, P., Grimme, L.H., Grönvall, F., Hamer, V., Scholze, M., Walter, H., (2003):
Water quality objectives for mixtures of toxic chemicals: problems and perspectives
Ecotox. Environ. Safe. 54 (2), 139 - 150
Volltext (DOI)
2002 (7)
- Altenburger, R., (2002):
Predicting toxic effects of contaminants in ecosystems using single species investigations
Habilitation, Universität Bremen, Fachbereich Biologie und Chemie
206 pp. - Brack, W., Altenburger, R., (2002):
Effektorientierte Identifikation toxischer Verbindungen
Mitteilungen der Fachgruppe Umweltchemie und Ökotoxikologie / Gesellschaft Deutscher Chemiker 8 , 6 - 8 - Brack, W., Altenburger, R., Dorusch, F., Hubert, A., Möder, M., Morgenstern, P., Moschütz, S., Mothes, S., Schirmer, K., Wennrich, R., Wenzel, K.-D., Schüürmann, G., (2002):
Hochwasser 2002 - Chemische und toxische Belastung überschwemmter Gemeinden im Raum Bitterfeld
UWSF 14 (4), 213 - 220
Volltext (DOI) - Cleuvers, M., Altenburger, R., Ratte, H.T., (2002):
Combination effect of light and toxicity in algal tests
J. Environ. Qual. 31 (2), 539 - 547
Volltext (DOI) - Meene, R., Schüürmann, G., Altenburger, R., (2002):
pH-abhängige Algentoxizität von Phenolderivaten
Mitteilungen der Fachgruppe Umweltchemie und Ökotoxikologie / Gesellschaft Deutscher Chemiker 8 , 9 - 11 - Schirmer, K., Altenburger, R., Bopp, S.K., Weiß, H., (2002):
Toxicological monitoring for the assessment of natural attenuation as a remediation option
International conference on Risk Assessment of Large Contaminated Sites, Halle, Germany, 22.-23.2.2002 - Walter, H., Consolaro, F., Gramatica, P., Scholze, M., Altenburger, R., (2002):
Mixture toxicity of priority pollutants at no observed effect concentrations (NOECs)
Ecotoxicology 11 (5), 299 - 310
Volltext (DOI)
2001 (5)
- Faust, M., Altenburger, R., Backhaus, T., Blanck, H., Bödeker, W., Gramatica, P., Hamer, V., Scholze, M., Vighi, M., Grimme, L.H., (2001):
Predicting the joint algal toxicity of multi-component s-triazine mixtures at low-effect concentrations of individual toxicants
Aquat. Toxicol. 56 (1), 13 - 32
Volltext (DOI) - Knops, M., Altenburger, R., Segner, H., (2001):
Alterations of physiological energetics, growth and reproduction of Daphnia magna under toxicant stress
Aquat. Toxicol. 53 (2), 79 - 90
Volltext (DOI) - Küster, E., Dorusch, F., Weiß, H., Altenburger, R., (2001):
TRE-Toxicity-Reduction-Evaluation - Approaches for continuous effect monitoring of in situ groundwater remediation techniques
11th Annual Meeting of the Society of Environmental Toxicology and Chemistry (SETAC) Europe, Madrid, Spain, 6-10 May 2001
SETAC Europe, Brussels, - Scholze, M., Boedeker, W., Faust, M., Backhaus, T., Altenburger, R., Grimme, L.H., (2001):
A general best-fit method for concentration-response curves and the estimation of low-effect concentrations
Environ. Toxicol. Chem. 20 (2), 448 - 457
Volltext (DOI) - Segner, H., Altenburger, R., Jung, K., Schüürmann, G., (2001):
Ecotoxicity characterization of seepage waters from a Theisenschlamm pond discharging into riverine system
In: Daus, B., Weiß, H., (eds.)
Fine-grained residues from copper smelting and their environmental impacts
UFZ-Bericht 22/2001
UFZ Leipzig-Halle GmbH, Leipzig, p. 59 - 69
2000 (11)
- Altenburger, R., Backhaus, T., Boedeker, W., Faust, M., Scholze, M., Grimme, L.H., (2000):
Predictability of the toxicity of multiple chemical mixtures to Vibrio fischeri: Mixtures composed of similarly acting chemicals
Environ. Toxicol. Chem. 19 (9), 2341 - 2347
Volltext (DOI) - Altenburger, R., Backhaus, T., (2000):
Exposition und Toxizität - Der Faktor Zeit in Routinebiotests
In: Mücke, W., Link, M., (Hrsg.)
Biotests in der Praxis - Status und Perspektiven in Methodik und Anwendung
TU München, Institut für Toxikologie und Umwelthygiene; Dr. Bruno Lange GmbH Düsseldorf, S. 61 - 74 - Altenburger, R., Segner, H., (2000):
Anwendungen biologischer Testverfahren für ökotoxikologische Wirkungsanalysen
In: Fomin, A., Arndt, U., Elsner, D., Klumpp, A., (Hrsg.)
Bioindikation: Biologische Testverfahren. Beiträge und Diskussion - 2. Hohenheimer Workshop zur Bioindikation am Kraftwerk Altbach-Deizisau, 6.4.1998
Heimbach, Stuttgart, S. 23 - 31 - Backhaus, T., Altenburger, R., Boedeker, W., Faust, M., Scholze, M., Grimme, L.H., (2000):
Predictability of the toxicity of multiple chemical mixtures of dissimilarly acting chemicals to Vibrio fischeri
Environ. Toxicol. Chem. 19 (9), 2348 - 2356
Volltext (DOI) - Brack, W., Altenburger, R., (2000):
Identifikation giftiger Inhaltsstoffe - ein wichtiger Schritt zur Gefährdungsabschätzung und Sanierung
UFZ-Jahresbericht '98-'99
UFZ Leipzig-Halle GmbH, Leipzig, S. 26 - 34 - Brack, W., Altenburger, R., Ensenbach, U., Nehls, S., Segner, H., (2000):
Biotestorientierte Identifikation toxischer organischer Sedimentinhaltstoffe - Ein Beitrag zur Risikoanalyse komplexer Kontaminationen am Beispiel des Spittelwassers. Mitteilung Nr. 22. Sedimentbewertung in europäischen Flußgebieten. Beiträge zum internationalen Symposium vom 12.-14. April 1999
"Sedimentbewertung in europäischen Flußgebieten", Koblenz, 12.-14.4.1999
Bundesanstalt für Gewässerkunde, Koblenz, p. 135 - 141 - Brack, W., Altenburger, R., Ensenbach, U., Nehls, S., Segner, H., Schüürmann, G., (2000):
Wirkungsorientierte Identifikation toxischer organischer Inhaltsstoffe in Flußsedimenten
In: Friese, K., Witter, B., Miehlich, G., Rode, M., (Hrsg.)
Stoffhaushalt von Auenökosystemen. Böden und Hydrologie, Schadstoffe, Bewertungen
Springer, Berlin, Heidelberg, New York, S. 337 - 346
Volltext (DOI) - Faust, M., Altenburger, R., Backhaus, T., Boedeker, W., Scholze, M., Grimme, L.H., (2000):
Predictive assessment of the aquatic toxicity of multiple chemical mixtures
J. Environ. Qual. 29 (4), 1063 - 1068
Volltext (DOI) - Grimme, L.H., Altenburger, R., Backhaus, T., Faust, M., Bödeker, W., Scholze, M., (2000):
Kombinationswirkungen von Umweltchemikalien in der Ökotoxikologie. Konzepte für die Vorhersage und ihre experimentelle Prüfung
UWSF 12 , 226 - 234
Volltext (DOI) - Hafner, C., Jung, K., Gehre, M., Altenburger, R., Schüürmann, G., (2000):
Isotopenmassenspektrometrische 13C/15N-Traceruntersuchungen zur Wirkung von Chlororganika auf höhere Pflanzen am Beispiel von Pentachlorphenol
In: Fomin, A., Arndt, U., Elsner, D., Klumpp, A., (Hrsg.)
Bioindikation: Biologische Testverfahren. Beiträge und Diskussion - 2. Hohenheimer Workshop zur Bioindikation am Kraftwerk Altbach-Deizisau, 6.4.1998
Heimbach, Stuttgart, S. 199 - 204 - Schmitt, H., Altenburger, R., Jastorff, B., Schüürmann, G., (2000):
Quantitative structure-activity analysis of the algae toxicity of nitroaromatic compounds
Chem. Res. Toxicol. 13 (6), 441 - 450
Volltext (DOI)
1999 (5)
- Brack, W., Altenburger, R., Ensenbach, U., Möder, M., Segner, H., Schüürmann, G., (1999):
Bioassay-directed identification of organic toxicants in river sediment in the industrial region of Bitterfeld (Germany) - a contribution to hazard assessment
Arch. Environ. Contam. Toxicol 37 (2), 164 - 174
Volltext (DOI) - Brack, W., Altenburger, R., Ensenbach, U., Segner, H., Schüürmann, G., (1999):
Biotest-orientierte Identifikation toxischer Inhaltsstoffe in Sedimenten des Elbeeinzugsgebiets
In: Friese, K., Kirschner, K., Witter, B., (Hrsg.)
Stoffhaushalt von Auenökosystemen der Elbe und ihrer Nebenflüsse : Nähr- und Schadstoffe - Ökotoxikologie - Belastbarkeit von Flußauen. Workshop, 1. bis 3. Februar 1999 im UFZ-Umweltforschungszentrum Leipzig-Halle, Sektion Gewässerforschung Magdeburg
UFZ-Bericht 1/1999
UFZ Leipzig-Halle GmbH, Leipzig, S. 41 - 41 - Kortenkamp, A., Altenburger, R., (1999):
Approaches to assessing combination effects of oestrogenic environmental pollutants
Sci. Total Environ. 233 (1-3), 131 - 140
Volltext (DOI) - Praszczyk, B., Altenburger, R., Oehlmann, J., Markert, B., Schüürmann, G., (1999):
Brauchen wir einen Biotest mit höheren Pflanzen in der aquatischen Toxikologie?
In: Oehlmann, J., Markert, B., (Hrsg.)
Ökotoxikologie: Ökosystemare Ansätze und Methoden
ecomed, Landsberg am Lech, S. 151 - 163 - Schüürmann, G., Altenburger, R., Segner, H., Lenoir, D., Metzger, J.O., Schrenk, D., (1999):
Umweltchemie 1998
Nachr. Chem., Tech. Lab. 47 (3), 291 - 302
Volltext (DOI)
1998 (5)
- Brack, W., Altenburger, R., Ensenbach, U., Nehls, S., Segner, H., Schüürmann, G., (1998):
Identifikation ökotoxikologisch wirksamer Substanzen in Sedimenten des Spittelwassers
In: Geller, W., Punčochář, P., Bornhöft, D., Bouček, J., Feldmann, H., Guhr, H., Mohaupt, V., Simon, M., Smrtˇák, J., Spoustová, J., Uhlmann, O., (Hrsg.)
Gewässerschutz im Einzugsgebiet der Elbe. 8. Magdeburger Gewässerschutzseminar, Oktober 1998, Karlsbad (Tschechien)
B.G. Teubner, Stuttgart, Leipzig, S. 149 - 150
Volltext (DOI) - Ensenbach, U., Altenburger, R., Behrens, A., Brack, W., Knops, M., Navas, J.M., Nehls, S., Schrag, B., Segner, H., Sturm, A., Walter, H., Schüürmann, G., (1998):
Ökotoxikologische Analyse komplexer Stoffgemische
Tagungsbericht 1997 der Deutschen Gesellschaft für Limnologie (DGL) und der deutschen und österreichischen Sektion der Societas Internationalis Limnologiae (SIL). Band II, Frankfurt am Main, 22. - 26.9.1997
Deutsche Gesellschaft für Limnologie, Krefeld, p. 882 - 885 - Ensenbach, U., Altenburger, R., Brack, W., Paschke, A., Popp, P., Segner, H., Wennrich, R., Schüürmann, G., (1998):
Ökotoxikologische Charakterisierung von Sedimenten der Saale
In: Geller, W., Punčochář, P., Bornhöft, D., Bouček, J., Feldmann, H., Guhr, H., Mohaupt, V., Simon, M., Smrtˇák, J., Spoustová, J., Uhlmann, O., (Hrsg.)
Gewässerschutz im Einzugsgebiet der Elbe. 8. Magdeburger Gewässerschutzseminar, Oktober 1998, Karlsbad (Tschechien)
B.G. Teubner, Stuttgart, Leipzig, S. 151 - 152
Volltext (DOI) - Grimme, L.H., Altenburger, R., Backhaus, T., Bödeker, W., Faust, M., Scholze, M., (1998):
Vorhersagbarkeit und Beurteilung der aquatischen Toxizität von Stoffgemischen: Multiple Kombinationen von unähnlich wirkenden Substanzen in niedrigen Konzentrationen
UFZ-Bericht 25/1998
UFZ Leipzig-Halle GmbH, Leipzig, 319 S. - Kortenkamp, A., Altenburger, R., (1998):
Synergisms with mixtures of xenoestrogens: A reevaluation using the method of isoboles
Sci. Total Environ. 221 (1), 59 - 73
Volltext (DOI)
1997 (5)
- Altenburger, R., Ensenbach, U., Jung, K., Knops, M., Popp, P., Segner, H., Weiß, H., Schüürmann, G., (1997):
Ecotoxicity identification for the hazard characterization of groundwater contamination: a fingerprint approach for a contaminated site at Bitterfeld
In: Alef, K., Brandt, J., Fiedler, H., Hauthal, W., Hutzinger, O., Mackay, D., Matthies, M., Morgan, K., Newland, L., Robitaille, H., Schlummer, M., Schüürmann, G., Voigt, K., (eds.)
Information and Communication in Environmental and Health Issues. ECO-INFORMA '97, 6.-9.10.1997, Neuherberg
Eco-Informa Vol. 12
Eco-Informa Press, Bayreuth, p. 452 - 457 - Altenburger, R., Ensenbach, U., Jung, K., Knops, M., Segner, H., (1997):
Ökotoxikologische Untersuchungen an Grundwasserproben
In: Weiß, H., Teutsch, G., Daus, B., (Hrsg.)
Sanierungsforschung in regional kontaminierten Aquiferen (SAFIRA): Bericht zur Machbarkeitsstudie für den Modellstandort Bitterfeld
UFZ-Bericht 27/1997
UFZ Leipzig-Halle GmbH, Leipzig, S. 94 - 98 - Altenburger, R., Schüürmann, G., (1997):
Instrumentarien zur Bewertung möglicher Kombinationswirkungen von Schadstoffen auf die menschliche Gesundheit
Integrierte Bewertung radiologischer und chemisch-toxischer Kontaminanten: Workshop am 24.11.1997
Sächsisches Staatsministerium für Umwelt und Landesentwicklung, Dresden, p. 27 - 35 - Backhaus, T., Froehner, K., Altenburger, R., Grimme, L.H., (1997):
Toxicity testing with Vibrio fischeri: A comparison between the long term (24 h) and the short term (30 min) bioassay
Chemosphere 35 (12), 2925 - 2938
Volltext (DOI) - Leibfritz, D., Altenburger, R., (1997):
Cell suspensions
In: Grant, D.M., Harris, R.K., (eds.)
Encyclopedia of nuclear magnetic resonance. Vol. 2
Wiley, New York, p. 1197 - 1209