Details zur Publikation
Kategorie Textpublikation
Referenztyp Zeitschriften
DOI 10.1007/s00284-005-0239-z
Volltext Shareable Link
Titel (primär) Biotransformation of 1-naphthol by a strictly aquatic fungus
Autor Augustin, T.; Schlosser, D. ORCID logo ; Baumbach, R.; Schmidt, J.; Grancharov, K.; Krauss, G.; Krauss, G.-J.
Quelle Current Microbiology
Erscheinungsjahr 2006
Department UMB
Band/Volume 52
Heft 3
Seite von 216
Seite bis 220
Sprache englisch
Abstract The aquatic hyphomycete Heliscus lugdunensis belongs to a group of exclusively aquatic mitosporic fungi with an only scarcely explored potential to oxidatively attack xenobiotic compounds, and was used to study the biotransformation of the environmental pollutant metabolite 1-naphthol. H. lugdunensis metabolized approximately 74% of 1-naphthol within 5 days. The identification and quantification of degradation products using gas chromatography-mass spectrometry, liquid chromatography-mass spectrometry, and high performance liquid chromatography revealed that approximately 12% of the parent compound was converted into 1-naphthylsulfate, 3% was transformed into 1-methoxy-naphthalene, and less than 1% was converted into 1,4-naphthoquinone. A further metabolite, most likely 4-hydroxy-1-naphthylsulfate, was also detected. In contrast to sulfate conjugate metabolites, no glucuronide and glucoside conjugates of 1-naphthol were found, and neither UDP-glucuronyltransferase nor UDP-glucosyltransferase present in H. lugdunensis showed activity towards 1-naphthol. These results support a role of fungi adapted to aquatic environments in affecting the environmental fate of pollutants in aquatic ecosystems.
dauerhafte UFZ-Verlinkung https://www.ufz.de/index.php?en=20939&ufzPublicationIdentifier=2460
Augustin, T., Schlosser, D., Baumbach, R., Schmidt, J., Grancharov, K., Krauss, G., Krauss, G.-J. (2006):
Biotransformation of 1-naphthol by a strictly aquatic fungus
Curr. Microbiol. 52 (3), 216 - 220 10.1007/s00284-005-0239-z