Sanja Koprivica

Current position:

PhD at Rudjer Boskovic Institute, Zagreb, Croatia



Sanja Koprivica

Current research

The specific topic of the PhD project is the development of novel isolation and fractionation procedures for comprehensive characterisation of contaminants using effect-directed analyses (EDA).
Combined extraction/fractionation protocols, involving different sorption/ion exchange mechanisms, were investigated with the aim to develop practical and highly efficient procedures, providing high yields for a wide variety of non-ionic and ionic organic compounds. The fractionation procedures were developed using a tiered approach, which allows development of a simple protocol suitable for the routine EDA screening as well as protocols for higher tier fractionation.
Chemical characterization of the fractionated extracts was performed in a comprehensive manner, using an integrated procedure, combining complementary features of high-resolution gas chromatography/mass spectrometry (GC/MS) and ultra-performance liquid chromatography /quadrupole-time-of- flight mass spectrometry (UPLC/QTOF) for the structural elucidation.
The developed procedure for ecotoxicological assessment of organic contaminants will be applied in detailed EDA studies that will be carried out at the selected locations in Croatia.


  • GC/MS
  • Preparative HPLC
  • Solid-phase extraction (SPE) of the complex mixtures involving different SPE materials (e.g. HLB, anionic and cationic exchangers)
  • Fractionation protocols combining different chromatographic systems (NP-LC, RP-LC, SE-LC)

Research interests

  • Development and application of integrated procedures for the isolation and identification of toxicants in complex environmental mixtures using effect-directed analysis (EDA).
  • Target and non-target screening of organic compounds in environmental samples using UPLC-MS/MS and GC-MS.

Curriculum vitae

Since 2012

PhD Student at the Faculty of Sciences, University of Zagreb, Croatia
2012- Marie Curie Fellow within EDA EMERGE FP7 project; Rudjer Boskovic Institute, Division for Marine and Environmental Research Zagreb, Croatia

2009 - 2012

Researcher on FP7 project “CEFSER- Reinforcing research potential in the Laboratory for Chemical Contaminants at the Faculty of Technology towards the establishment of the Center of Excellence in Food Safety and Emerging Risks”, Faculty of Technology, University of Novi Sad, Serbia


BSc (10 semesters, recognized as MSc), Faculty of Technology, University of Novi Sad, Serbia


Sanja Koprivica, Iva Mikac, Senka Terzic, Marijan Ahel, Comparison of two simplified fractionation protocols for the assessment of organic contaminants in aqueous samples using effect-directed analysis, Poster presentation at the SETAC Europe 24th Annual Meeting, May 2014, Basel, Switzerland.

Sanja Koprivica, Ivona Krizman, Iva Mikac, Ivan Senta, Senka Terzić, Marijan Ahel, Evaluation Of An Integrated Protocol For Non-Target Analysis Of Hydrophobic And Polar Contaminants In Aqueous Samples Using Gas Chromatography/Mass Spectrometry And Liquid Chromatography/Time-Of-Flight Mass Spectrometry. Poster presentation at 19th International Symposium on Separation Sciences, New Achievements in Chromatography, September 2013, Poreč, Croatia.


Werner Brack, Selvan Govender, Tobias Schulze, Martin Krauss, Meng Hu, Melis Muz, Juliane Hollender, Kristin Schirmer, Jennifer Schollee, Anita Hidasi, Jaroslav Slobodnik, Zuzana Rabova, Selim Ait-Aissa, Manoj Sonavane, Mario Carere, Marja Lamoree, Pim Leonards, Sara Tufi, Xiyu Ouyang, Merijn Schriks, Kevin Thomas, Ana Catarina de Almeida, Jean Froment, Monika Hammers-Wirtz, Marijan Ahel, Sanja Koprivica, Henner Hollert, Thomas-Benjamin Seiler, Carolina Di Paolo, Andrew Tindall and Petra Spirhanzlova, 2013. EDA-EMERGE: an FP7 initial training network to equip the next generation of young scientists with the skills to address the complexity of environmental contamination with emerging pollutants. Environmental Sciences Europe 25, 18 (DOI: 10.1186/10.1186/2190-4715-25-18)

Biljana Skrbic, Sanja Koprivica, Michal Godula, Validation of a method for determination of mycotoxins subjected to the EU regulations in spices: The UHPLC-HESI-MS/MS analysis of the crude extracts, Food Control, 31 (2013) 461-466.


EDA-EMERGE Newsletter



Marie Curie ITN EU-FP7 project