Dr. Isabel Karkossa

(Née Kratochvil)

Postdoc in the group of Functional Genomics.

Contact

Department of Molecular Systems Biology (MOLSYB)
Helmholtz-Centre for Environmental Research - UFZ
Permoser Str. 15
04318 Leipzig

Tel: +49 341 235 1354
isabel.karkossa@ufz.de
ResearchGate
@IKarkossa

IK

Research

  • Investigating the modes of action of environmental contaminants in immune cells
  • Proteomics


Curriculum Vitae

2019 - today

Postdoc
Helmholtz-Centre for Environmental Research - UFZ, Leipzig, Germany
Proteomics for assessment of nanomaterial effects

2016 - 2019

PhD project
Helmholtz-Centre for Environmental Research - UFZ, Leipzig, Germany
Proteomics for assessment of nanomaterial effects

2015

Research project
Vanderbilt University, Nashville, TN, USA
Investigation of biomolecules using ion mobility mass spectrometry

2014 - 2016

Master of Science (Biochemistry)
Leipzig University, Leipzig, Germany
Investigation of interactions between PPARγ and phthalates using HDX-MS

2011 - 2014

Bachelor of Science (Biochemistry)
Martin-Luther-University Halle-Wittenberg, Halle (Saale), Germany
Evaluation of a cleavable cross-linker for peptide structure analysis


Publications

2024 (1)

2023 (11)

2022 (5)

2021 (11)

2020 (5)

2019 (4)

2018 (1)

  • Ihling, C., Falvo, F., Kratochvil, I., Sinz, A., & Schäfer, M. (2015). Dissociation behavior of a bifunctional tempo-active ester reagent for peptide structure analysis by free radical initiated peptide sequencing (FRIPS) mass spectrometry. J Mass Spectrom, 50(2), 396-406

Posters & Talks

Karkossa, I., Bannuscher, A., Hellack, B., Wohlleben, W., Laloy, J., Stan, M.S., Dinischiotu, A., Wiemann, M., Luch, L., Haase, A., von Bergen, M., Schubert, K. (2021). Omics reveal different oxidative stress levels induced by nanomaterials in vitro and in vivo. Poster presented at the Eurotox, virtual meeting.

Karkossa, I., Bannuscher, A., Hellack, B., Haase, A., Schubert, K., von Bergen, M. (2019). Weighted Gene Correlation Network Analysis of multi-omics data highlights effect-inducing properties and biomarker candidates: An application for nanomaterial grouping. Poster presented at the Young Scientists Fall Meeting of the German Society of Mass Spectrometry, Hünfeld, Germany.

Karkossa, I., Bannuscher, A., Hellack, B., von Bergen, M., Haase, A., Schubert, K. (2019). Nanomaterials affect oxidative phosphorylation and phagocytosis in alveolar macrophages. Poster presented at Joint Meeting of the German Society for Immunology and the Italian Society of Immunology, München, Germany.

Kratochvil, I., Bannuscher, A., Hellack, B., Haase A., Schubert, K., von Bergen, M. (2019). Multi-Omics to Develop Nanomaterial Grouping Strategies for Risk Assessment. Poster presented at Proteomic Forum, Potsdam, Germany.

Kratochvil, I., Bannuscher, A., Kettler, K., Haase A., von Bergen, M., Schubert, K. (2018). Weighted Gene Correlation Network Analysis to develop nanomaterial grouping strategies. Talk at 9th International Conference on Nanotoxicology, Neuss, Germany.

Kratochvil, I., Bannuscher, A., Kettler, K., Haase A., Schubert, K., von Bergen, M. (2018). Weighted Gene Correlation Network Analysis as Grouping Strategy for Nanomaterial Risk Assessment in Alveolar Macrophages. Poster presented at European Mass Spectrometry Conference, Saarbrücken, Germany.

Kratochvil, I., Bannuscher, A., Haase A., Schubert K., von Bergen, M. (2018). Weighted Gene Correlation Network Analysis as Grouping Strategy for Nanomaterial Risk Assessment. Poster presented at Research Festival, Leipzig, Germany.

Kratochvil, I., Hofmann, T., Schlichting R., Escher E., Kalkhof, S., von Bergen, M. (2017). MEHP and MEOHP but not DEHP bind and activate the peroxisome proliferator-activated receptor γ. Poster presented at meeting of German Society of Mass Spectrometry, Kiel, Germany.