Prof. Dr. Jörg Hackermüller

Head of Department Computational Biology and Chemistry (COMPBC)


Helmholtz Centre for Environmental Research - UFZ
Permoserstr. 15
04318 Leipzig, Germany

Phone: +49 341 235 1561


Social network


Research interests

  • Bioinformatic method development for omics data analysis and integration
  • Non-coding RNAs in disease and toxicity, drug discovery, and as biomarkers
  • Using omics data in chemical risk assessment and for understanding mechanisms of toxicity
  • Environmental epigenetics, gene – environment interactions
  • Developing artificial intelligence approaches for toxicological problems
  • Investigating the potential of single-cell omics in toxicology and environmental health
  • RNA-based mechanisms

CV

Professional experience

Since 2024 Head of Department, Department Computational Biology and Chemistry, Helmholtz Centre for Environmental Research – UFZ
Since 2021 Professor of Computational Biology at the Faculty of Mathematics and Computer Science at Leipzig University
2021 - 2023 Head of Department, Department Computational Biology, Helmholtz Centre for Environmental Research – UFZ
2011 - 2021 Head of Group, Helmholtz-University Young Investigators Group Bioinformatics & Transcriptomics
Helmholtz Centre for Environmental Research – UFZ and University of Leipzig, Faculty for Mathematics and Informatics
2010 Junior Faculty, University of Leipzig, Faculty for Mathematics and Informatics
2007 - 2014 Head of Group, RNomics Group
Fraunhofer Institute for Cell Therapy and Immunology IZI
(Since 2010 as secondary employment)
2005 - 2007 Post Doctoral Scientist, RNomics Group
Fraunhofer Institute for Cell Therapy and Immunology IZI 
2005 Post Doctoral Scientist, Innovative Screening Technologies Unit
Novartis Institutes for Biomedical Research
2002 - 2005 PhD Student, In Silico Sciences Unit
Novartis Institutes for Biomedical Research
Education  
2005 PhD (Dr. rer. nat.) in Chemistry
University Vienna
2001 Diploma in Chemistry (Biochemistry, Theoretical Chemistry)
University Vienna


Publications


Recent preprints

Lisa Maria Steinheuer, Sebastian Canzler, Jörg Hackermüller. Benchmarking scRNA-seq imputation tools with respect to network inference highlights deficits in performance at high levels of sparsity.
bioRxiv 2021.04.02.438193; doi: https://doi.org/10.1101/2021.04.02.438193


Sebastian Canzler, Jörg Hackermüller. multiGSEA: A GSEA-based pathway enrichment analysis for multi-omics data. bioRxiv 2020.07.17.208215; doi: https://doi.org/10.1101/2020.07.17.208215

Sebastian Canzler, Jörg Hackermüller, Jana Schor. MOD-Finder: Identify multi-omics data sets related to defined chemical exposure. 2019. arXiv:1907.06346