Dr. Arkadiusz Pierzchalski
Contact
Dr. Arkadiusz Pierzchalski
Scientist, Platform Coordinator of
Flow cytometry
Helmholtz Centre for
Environmental Research – UFZ
Department of Environmental Immunology
Permoserstr. 15
04318 Leipzig, Germany
Phone: +49 341 6025-1548
Email
Research Interests
- Cytometry technology development
- Influence of environmental factors on regulatory T cells and mucosal-associated invariant T cells function
- In-depth immune cells characterization with flow cytometry
Curriculum vitae / Scientific career
Since 2015
Scientist at the Helmholtz Centre for Environmental Research Leipzig - UFZ, Department Environmental Immunology
02/2014 - 12/2014
Scientist at the Clinics of University of Leipzig, “Pathogenesis of New Allergies”
04/2011 - 05/2013
Principal Investigator “Cytomics parameters for ex vivo expansion of regulatory Cells (Tregs) for immune tolerance ", Translational Centre for Regenerative Medicine (TRM), University of Leipzig
01/2009 - 03/2011
Scientist at the Translational Centre for Regenerative Medicine (TRM), University of Leipzig
04/2007 - 12/2008
Scientist at the Heart Centre at Medical University of Leipzig
10/2006 - 12/2006
Internship at the University of Stuttgart, Institute of Cell Biology and Immunology
08/2006 - 09/2006
Internship at the LIONEX GmbH, Braunschweig
02/2006 - 08/2007
Scientist at the Medical University of Gdañsk, Poland
2001 - 2005
PhD Student of Postgraduate School of Molecular Medicine in Warsaw
2000 - 2007
PhD Student at the Institute for Medical Biotechnology, Medical University Gdañsk,
PhD thesis: "Analysis of TNF receptor activation by soluble and membrane form of TNF in U937 cells"
1995 - 2000
Student at Intercollegiate Faculty of Biotechnology at University of Gdañsk (Danzig, Poland)
Diploma thesis: "Analysis of IL-1 and TNF-induced cell death of KB cells"
Awards and Scholarships
1999
Letter of Congratulations from a Dean of the Faculty of Biotechnology
1999 - 2000
Scholarship from the Major of Sopot
06/2000 - 09/2000
SOCRATES/ERASMUS Grant, Santiago de Compostela, Spain - Mechanisms of the cell cycle regulation
2003
Team reward by Rector of Medical Academy of Gdañsk for the work on TNF receptors
2006
Personal reward of Council of Faculty of Biotechnology for the success in education of biotechnology students
Publications
Index:
You could use our publication index for further requests.
2024 (3)
- Maddalon, A., Pierzchalski, A., Krause, J.L., Bauer, M., Finckh, S., Brack, W., Zenclussen, A.C., Marinovich, M., Corsini, E., Krauss, M., Herberth, G. (2024):
Impact of chemical mixtures from wastewater treatment plant effluents on human immune cell activation: An effect-based analysis
Sci. Total Environ. 906 , art. 167495 10.1016/j.scitotenv.2023.167495 - Pierzchalski, A., Zenclussen, A.C., Herberth, G. (2024):
A comprehensive battery of flow cytometric immunoassays for the in vitro testing of chemical effects in human blood cells
Front. Immunol. 14 , art. 1327960 10.3389/fimmu.2023.1327960 - Snapkow, I., Smith, N.M., Arnesdotter, E., Beekmann, K., Blanc, E.B., Braeuning, A., Corsini, E., Sollner Dolenc, M., Duivenvoorde, L.P.M., Eriksen, G.E., Franko, N., Galbiati, V., Gostner, J.M., Grova, N., Gutleb, A.C., Hargitai, R., Janssen, A.W.F., Krapf, S.A., Lindeman, B., Lumniczky, K., Maddalon, A., Mollerup, S., Parráková, L., Pierzchalski, A., Pieters, R.H.H., Silva, M.J., Solhaug, A., Staal, Y.C.M., Straumfors, A., Szatmári, T., Turner, J.D., Vandebriel, R.J., Zenclussen, A.C., Barouki, R. (2024):
New approach methodologies to enhance human health risk assessment of immunotoxic properties of chemicals - a PARC (Partnership for the Assessment of Risk from Chemicals) project
Front. Toxicol. 6 10.3389/ftox.2024.1339104
2023 (4)
- Krause, J.L., Pierzchalski, A., Chang, H.D., Zenclussen, A.C., Bauer, M., Herberth, G. (2023):
Bisphenols, but not phthalate esters, modulate gene expression in activated human MAIT cells in vitro
Toxicol. Rep. 10 , 348 - 356 10.1016/j.toxrep.2023.02.017 - Maddalon, A., Pierzchalski, A., Kretschmer, T., Bauer, M., Zenclussen, A.C., Marinovich, M., Corsini, E., Herberth, G. (2023):
Mixtures of per- and poly-fluoroalkyl substances (PFAS) reduce the in vitro activation of human T cells and basophils
Chemosphere 336 , art. 139204 10.1016/j.chemosphere.2023.139204 - Pfannes, R., Pierzchalski, A., Maddalon, A., Simion, A., Zouboulis, C.C., Behre, G., Zenclussen, A.C., Westphal, S., Fest, S., Herberth, G. (2023):
Characterization of post-vaccination SARS-CoV-2 T cell subtypes in patients with different hematologic malignancies and treatments
Front. Immunol. 14 , art. 1087996 10.3389/fimmu.2023.1087996 - Pierzchalski, A., Zenclussen, A.C., Herberth, G. (2023):
OMIP-94: Twenty-four-color (thirty-marker) panel for deep immunophenotyping of immune cells in human peripheral blood
Cytom. Part A 103 (9), 695 - 702 10.1002/cyto.a.24766
2022 (1)
- Krause, J.L., Engelmann, B., Nunes da Rocha, U., Pierzchalski, A., Chang, H.D., Zenclussen, A.C., von Bergen, M., Rolle-Kampczyk, U., Herberth, G. (2022):
MAIT cell activation is reduced by direct and microbiota-mediated exposure to bisphenols
Environ. Int. 158 , art. 106985 10.1016/j.envint.2021.106985
2020 (3)
- Krause, J.L., Schäpe, S.S., Schattenberg, F., Müller, S., Ackermann, G., Rolle-Kampczyk, U.E., Jehmlich, N., Pierzchalski, A., von Bergen, M., Herberth, G. (2020):
The activation of mucosal-associated invariant T (MAIT) cells is affected by microbial diversity and riboflavin utilization in vitro
Front. Microbiol. 11 , art. 755 10.3389/fmicb.2020.00755 - Mendler, A., Geier, F., Haange, S.-B., Pierzchalski, A., Krause, J.L., Nijenhuis, I., Froment, J., Jehmlich, N., Berger, U., Ackermann, G., Rolle-Kampczyk, U., von Bergen, M., Herberth, G. (2020):
Mucosal-associated invariant T-Cell (MAIT) activation is altered by chlorpyrifos- and glyphosate-treated commensal gut bacteria
J. Immunotoxicol. 17 (1), 10 - 20 10.1080/1547691X.2019.1706672 - Mendler, A., Pierzchalski, A., Bauer, M., Röder, S., Sattler, A., Standl, M., Borte, M., von Bergen, M., Rolle-Kampczyk, U., Herberth, G. (2020):
MAIT cell activation in adolescents is impacted by bile acid concentrations and body weight
Clin. Exp. Immunol. 200 (2), 199 - 213 10.1111/cei.13423
2019 (1)
- Bauer, M., Hackermüller, J., Schor, J., Schreiber, S., Fink, B., Pierzchalski, A., Herberth, G. (2019):
Specific induction of the unique GPR15 expression in heterogeneous blood lymphocytes by tobacco smoking
Biomarkers 24 (3), 217 - 224 10.1080/1354750X.2018.1539769
2017 (1)
- Herberth, G., Pierzchalski, A., Feltens, R., Bauer, M., Röder, S., Olek, S., Hinz, D., Borte, M., von Bergen, M., Lehmann, I. (2017):
Prenatal phthalate exposure associates with low regulatory T-cell numbers and atopic dermatitis in early childhood: Results from the LINA mother-child study. Letter to the editor
J. Allergy Clin. Immunol. 139 (4), 1376 - 1379.e8 10.1016/j.jaci.2016.09.034