Research for the Environment

Dr. Tobias Schulze

Contact

Dr. Tobias Schulze
Research Scientist | Ecotoxicologist

Department Effect-Directed Analysis
Helmholtz Centre for
Environmental Research - UFZ
Permoserstraße 15
04318 Leipzig, Germany

phone +49 341 235 1083
fax +49 341 235 451083
tobias.schulze@ufz.de

Tobias Schulze

Research interests

  • Effect-directed analysis (EDA) of complex environmental samples
  • Nontarget screening of organic compounds in environmental samples using LC-MS/MS and GC-MS
  • Computer tools and statistical approaches for structure elucidation, toxicant identification and pattern recognition
  • Community driven mass spectra databases, open access data and data sharing
  • Sampling techniques and procedures for aquatic samples (water, sediments, suspended particulate matter, passive sampling)
  • Bioavailability of sediment-associated contaminants

Current projects

Finished projects

  • LPDA (Low Pressure Dialytic Analysis)-Laborgerät und –verfahren mit Hilfe spezieller semipermeabler Dialysemembranen zur Aufreinigung matrixbeeinflusster Substanzextrakte (AiF-FKZ KF0011005UL6)
  • MODELKEY Models for Assessing and Forecasting the Impact of Environmental Key Pollutants on Marine and Freshwater Ecosystems and Biodiversity (EU Contract-No. 511237 (GOCE))

Collaborations

Professional memberships

  • Society of Environmental Toxicology and Chemistry (SETAC)
  • Member of DIN working group “Sampling” of NA 119 Water Practice Standards Committee (German Institute for Standardisation)
  • Member of NORMAN working group 3 "Effect-directed analysis for hazardous pollutant identification"

Curriculum Vitae

Nov. 2010

since 2007

Scientist at the Department of Effect-Directed Analysis, Helmholtz Centre for Environmental Research - UFZ

2000 - 2006

Scientist at the Department of Earth Sciences, Free University Berlin

1993 - 1999

Diploma in geography, geology and chemistry at Free University Berlin with focus on environmental chemistry and hydrogeology

Key publications (see below for full list of publications)

  • Lübcke-von Varel, U., Bataineh, M., Löffler, I., Schulze, T., Flückiger-Isler, S., Neca, J., Machala, M., Brack, W., Lohrmann, S., (2012):
    Identification and quantitative confirmation of dinitropyrenes and 3-nitrobenzanthrone as major mutagens in contaminated sediments
    Environ. Int. 44 (September 2012), 31 - 39
    full text (url)
  • Schulze, T., Magerl, R., Streck, G., Brack, W., (2012):
    Use of factorial design for the multivariate optimization of polypropylene membranes for the cleanup of environmental samples using the accelerated membrane-assisted cleanup approach
    J. Chromatogr. A 1225 , 26 - 36
    full text (url)
  • Schymanski, E.L., Gallampois, C.M.J., Krauss, M., Meringer, M., Neumann, S., Schulze, T., Wolf, S., Brack, W., (2012):
    Consensus structure elucidation combining GC/EI-MS, structure generation and calculated properties
    Anal. Chem. 84 (7), 3287 - 3295
    full text (url)
  • Wölz, J., Grosshans, K., Streck, G., Schulze, T., Rastall, A., Erdinger, L., Brack, W., Fleig, M., Kühlers, D., Braunbeck, T., Hollert, H., (2011):
    Estrogen receptor mediated activity in bankside groundwater, with flood suspended particulate matter and floodplain soil – an approach combining tracer substance, bioassay and target analysis
    Chemosphere 85 (5), 717 - 723
    full text (url)
  • Schulze, T., Weiss, S., Schymanski, E., von der Ohe, P.C., Schmitt-Jansen, M., Altenburger, R., Streck, G., Brack, W., (2010):
    Identification of a phytotoxic photo-transformation product of diclofenac using effect-directed analysis
    Environ. Pollut. 158 (5), 1461 - 1466
    full text (url)
  • Brack, W., Bandow, N., Schwab, K., Schulze, T., Streck, G., (2009):
    Bioavailability in effect-directed analysis of organic toxicants in sediments
    Trac-Trends Anal. Chem. 28 (5), 543 - 549
    full text (url)
  • Kaisarevic, S., Lübcke-von Varel, U., Orcic, D., Streck, G., Schulze, T., Pogrmic, K., Teodorovic, I., Brack, W., Kovacevic, R., (2009):
    Effect-directed analysis of contaminated sediment from the wastewater canal in Pancevo industrial area, Serbia
    Chemosphere 77 (7), 907 - 913
    full text (url)
  • Brack, W., Schmitt-Jansen, M., Machala, M., Brix, R., Barcelo, D., Schymanski, E., Streck, G., Schulze, T., (2008):
    How to confirm identified toxicants in effect-directed analysis
    Anal. Bioanal. Chem. 390 (8), 1959 - 1973
    full text (url)
  • Seiler, T.-B., Schulze, T., Hollert, H., (2008):
    The risk of altering soil and sediment samples upon extract preparation for analytical and bio-analytical investigations - a review
    Anal. Bioanal. Chem. 390 (8), 1975 - 1985
    full text (url)
  • Streck, G., Schulze, T., Brack, W., (2008):
    Accelerated membrane-assisted clean-up as a tool for the clean-up of extracts from biological tissues
    J. Chromatogr. A 1196-1197 , 33 - 40
    full text (url)
  • Schulze, T., Ricking, M., Schöter-Kermani, C., Körner, A., Denner, H.D., Weinfurtner, K., Winkler, A., Pekdeger, A., (2007):
    The German Environmental Specimen Bank - Sampling, processing, and archiving sediment and suspended particulate matter
    J. Soils Sediments 7 (6), 361 - 367
    full text (url)

Full list of publications

Index:

2012 (7)
2011 (5)
2010 (2)
2009 (4)
2008 (4)
2007 (5)
2005 (2)
2003 (3)
2002 (1)

You could use our publication index for further requests.

2012 (7)

  • Higley, E., Grund, S., Jones, P.D., Schulze, T., Seiler, T.-B., Lübcke-von Varel, U., Brack, W., Wölz, J., Zielke, H., Giesy, J.P., Hollert, H., Hecker, M., (2012):
    Endocrine disrupting, mutagenic, and teratogenic effects of upper Danube River sediments using effect-directed analysis
    Environ. Toxicol. Chem. 31 (5), 1053 - 1062
    full text (url)
  • Lübcke-von Varel, U., Bataineh, M., Löffler, I., Schulze, T., Flückiger-Isler, S., Neca, J., Machala, M., Brack, W., Lohrmann, S., (2012):
    Identification and quantitative confirmation of dinitropyrenes and 3-nitrobenzanthrone as major mutagens in contaminated sediments
    Environ. Int. 44 (September 2012), 31 - 39
    full text (url)
  • Schulze, T., Brack, W., Walz, K.-H., (2012):
    Verfahren und Vorrichtung zur Festphasenextraktion aus einer Flüssigkeit
    Europäisches Patentamt, München
  • Schulze, T., Magerl, R., Streck, G., Brack, W., (2012):
    Use of factorial design for the multivariate optimization of polypropylene membranes for the cleanup of environmental samples using the accelerated membrane-assisted cleanup approach
    J. Chromatogr. A 1225 , 26 - 36
    full text (url)
  • Schulze, T., Schymanski, E., Stravs, M., Neumann, S., Krauss, M., Singer, H., Hug, C., Gallampois, C., Hollender, J., Slobodnik, J., Brack, W., (2012):
    NORMAN MassBank: Towards a community-driven, open-access accurate mass spectral database for the identification of emerging pollutants
    Norman Bulletin 2012/3
    NORMAN Network, p. 9 - 11
  • Schulze, T., Seiler, T.-B., Streck, G., Braunbeck, T., Hollert, H., (2012):
    Comparison of different exhaustive and biomimetic extraction techniques for chemical and biological analysis of polycyclic aromatic compounds in river sediments
    J. Soils Sediments 12 (9), 1419 - 1434
    full text (url)
  • Schymanski, E.L., Gallampois, C.M.J., Krauss, M., Meringer, M., Neumann, S., Schulze, T., Wolf, S., Brack, W., (2012):
    Consensus structure elucidation combining GC/EI-MS, structure generation and calculated properties
    Anal. Chem. 84 (7), 3287 - 3295
    full text (url)
to index

2011 (5)

  • dos Anjos, N.A., Schulze, T., Brack, W., Val, A.L., Schirmer, K., Scholz, S., (2011):
    Identification and evaluation of cyp1a transcript expression in fish as molecular biomarker for petroleum contamination in tropical fresh water ecosystems
    Aquat.Toxicol. 103 (1-2), 46 - 52
    full text (url)
  • Schulze, T., Streck, G., Paschke, A., (2011):
    Sampling and conservation
    In: Frimmel, F.H., (ed.)
    Treatise on Water Science Vol. 3: Aquatic Chemistry and Microbiology
    3
    Elsevier Science, Oxford, p. 131 - 152
    full text (url)
  • Schymanski, E., Schulze, T., Hermanns, J., Brack, W., (2011):
    Computer tools for structure elucidation in effect-directed analysis
    In: Brack, W., (ed.)
    Effect-directed analysis of complex environmental contamination
    Handbook of Environmental Chemistry Series 15
    Springer, Berlin, Heidelberg, p. 167 - 198
    full text (url)
  • Wölz, J., Grosshans, K., Streck, G., Schulze, T., Rastall, A., Erdinger, L., Brack, W., Fleig, M., Kühlers, D., Braunbeck, T., Hollert, H., (2011):
    Estrogen receptor mediated activity in bankside groundwater, with flood suspended particulate matter and floodplain soil – an approach combining tracer substance, bioassay and target analysis
    Chemosphere 85 (5), 717 - 723
    full text (url)
  • Wölz, J., Schulze, T., Lübcke-von Varel, U., Fleig, M., Reifferscheid, G., Brack, W., Kühlers, D., Braunbeck, T., Hollert, H., (2011):
    Investigation on soil contamination at recently inundated and non-inundated sites
    J. Soils Sediments 11 (1), 82 - 92
    full text (url)
to index

2010 (2)

  • Schulze, T., Weiss, S., Schymanski, E., von der Ohe, P.C., Schmitt-Jansen, M., Altenburger, R., Streck, G., Brack, W., (2010):
    Identification of a phytotoxic photo-transformation product of diclofenac using effect-directed analysis
    Environ. Pollut. 158 (5), 1461 - 1466
    full text (url)
  • Wölz, J., Fleig, M., Schulze, T., Maletz, S., Lübcke-von Varel, U., Reifferscheid, G., Kühlers, D., Braunbeck, T., Brack, W., Hollert, H., (2010):
    Impact of contaminants bound to suspended particulate matter in the context of flood events
    J. Soils Sediments 10 (6), 1174 - 1185
    full text (url)
to index

2009 (4)

  • Brack, W., Bandow, N., Schwab, K., Schulze, T., Streck, G., (2009):
    Identifizierung toxischer Verbindungen in Sedimenten: Ansätze zur Integration von Wirkung und Bioverfügbarkeit
    UWSF-Z.Umweltchem.Ökotox. 21 (3), 240 - 244
    full text (url)
  • Brack, W., Bandow, N., Schwab, K., Schulze, T., Streck, G., (2009):
    Bioavailability in effect-directed analysis of organic toxicants in sediments
    Trac-Trends Anal. Chem. 28 (5), 543 - 549
    full text (url)
  • Hollert, H., Claus, E., Ahlf, W., Brack, W., Braunbeck, T., Hudjetz, S., Manz, W., Ratte, H.T., Reifferscheid, G., Schäffer, A., Schulze, T., Schwarzbauer, J., Heininger, P., (2009):
    Über die Notwendigkeit der wirkungsorientierten Analytik in einer umfassenden Wasserforschung
    UWSF-Z.Umweltchem.Ökotox. 21 (3), 235 - 237
    full text (url)
  • Kaisarevic, S., Lübcke-von Varel, U., Orcic, D., Streck, G., Schulze, T., Pogrmic, K., Teodorovic, I., Brack, W., Kovacevic, R., (2009):
    Effect-directed analysis of contaminated sediment from the wastewater canal in Pancevo industrial area, Serbia
    Chemosphere 77 (7), 907 - 913
    full text (url)
to index

2008 (4)

  • Brack, W., Schmitt-Jansen, M., Machala, M., Brix, R., Barcelo, D., Schymanski, E., Streck, G., Schulze, T., (2008):
    How to confirm identified toxicants in effect-directed analysis
    Anal. Bioanal. Chem. 390 (8), 1959 - 1973
    full text (url)
  • Seiler, T.-B., Schulze, T., Hollert, H., (2008):
    The risk of altering soil and sediment samples upon extract preparation for analytical and bio-analytical investigations - a review
    Anal. Bioanal. Chem. 390 (8), 1975 - 1985
    full text (url)
  • Streck, G., Schulze, T., Brack, W., (2008):
    Accelerated membrane-assisted clean-up as a tool for the clean-up of extracts from biological tissues
    J. Chromatogr. A 1196-1197 , 33 - 40
    full text (url)
  • Streck, G., Schulze, T., Brack, W., (2008):
    Accelerated Membrane Assisted Clean-up: Eine leistungsfähige Methode zur Aufreinigung matrixbehafteter Extrakte
    LC-GC Ads März/April 2008 , 6 - 10
to index

2007 (5)

  • Rüdel, H., Bester, K., Eisenträger, A., Franzaring, J., Haarich, M., Köhler, J., Körner, W., Oehlmann, H., Paschke, A., Ricking, M., Schröder, W., Schröter-Kermani, C., Schulze, T., Schwarzbauer, J., Theobald, N., von der Trenck, T., Wagner, G., Wiesmüller, G.A., (2007):
    Stoffbezogenes Umweltmonitoring
    In: Wichmann, H.E., Schlipköter, H.W., Fülgraff, G., (Hrsg.)
    Handbuch der Umweltmedizin
    37. Erg.lfg. 10/07
    ecomed, Landsberg, S. IV-7.1
  • Rüdel, H., Bester, K., Eisenträger, A., Franzaring, J., Haarich, M., Köhler, J., Körner, W., Oehlmann, J., Paschke, A., Ricking, M., Schröder, W., Schröter-Kermani, C., Schulze, T., Schwarzbauer, J., Theobald, N., von der Trenck, T., Wagner, G., Wiesmüller, G.A., (2007):
    Positionspapier zum stoffbezogenen Umweltmonitoring (Teil 1 von 2)
    Gesellschaft Deutscher Chemiker / Mitteilungen der Fachgruppe Umweltchemie und Ökotoxikologie 13 (2), 34 - 41
  • Rüdel, H., Bester, K., Eisenträger, A., Franzaring, J., Haarich, M., Köhler, J., Körner, W., Oehlmann, J., Paschke, A., Ricking, M., Schröder, W., Schröter-Kermani, C., Schulze, T., Schwarzbauer, J., Theobald, N., von der Trenck, T., Wagner, G., Wiesmüller, G.A., (2007):
    Positionspapier zum stoffbezogenen Umweltmonitoring (Teil 2 von 2)
    Gesellschaft Deutscher Chemiker / Mitteilungen der Fachgruppe Umweltchemie und Ökotoxikologie 13 (3), 72 - 79
  • Schulze, T., Ricking, M., Pekdeger, A., Winkler, A., (2007):
    Validierung der SOPs ?Sediment und Schwebstoffe" unter Routinebedingungen - Abschlussbericht an das Umweltbundesamt (Dessau) (FKZ 301 02 018)
    Freie Universität Berlin, Berlin, 64 S.
  • Schulze, T., Ricking, M., Schöter-Kermani, C., Körner, A., Denner, H.D., Weinfurtner, K., Winkler, A., Pekdeger, A., (2007):
    The German Environmental Specimen Bank - Sampling, processing, and archiving sediment and suspended particulate matter
    J. Soils Sediments 7 (6), 361 - 367
    full text (url)
to index

2005 (2)

  • Hallare, A.V., Kosmehl, T., Schulze, T., Hollert, H., Köhler, H.R., Triebskorn, R., (2005):
    Assessing contamination levels of Laguna Lake sediments (Philippines) using a contact assay with zebrafish (Danio rerio) embryos
    Sci. Total Environ. 347 (1-3), 254 - 271
    full text (url)
  • Schulze, T., Ricking, M., Pekdeger, A., Winkler, A., (2005):
    Entwicklung einer Verfahrensrichtlinie Sedimente und Schwebstoffe - Abschlussbericht an das Umweltbundesamt (Dessau) (FKZ 301 02 013)
    Freie Universität Berlin, Berlin, 128 S.
to index

2003 (3)

  • Hollert, H., Ulrich, M., Schulze, T., Terytze, K., Braunbeck, T., (2003):
    Ökotoxikologische Bewertung von Rheinsedimenten und Schwebstoffen in Überflutungsgebieten
    Universität Heidelberg Institut für Zoologie, Heidelberg, 185 S.
  • Ricking, M., Schulze, T., (2003):
    Deep-freeze sampling methods for soft sediments
    In: Locat, J., Cloutier, R.G., Chaney, R., Demars, K., (eds.)
    Contaminated sediments: characterization, evaluation, mitigation/restoration, and management strategy performance
    ASTM Special Technical Publication 1442
    ASTM International, West Conshohocken, PA, p. 28 - 35
  • Schulze, T., Wetterauer, B., Schwarzbauer, J., Hollert, H., Braunbeck, T., Ricking, M., (2003):
    DDT und Metabolite in Sedimenten Berliner Gewässer - Vorkommen, Analytik und Schädigungspotenzial
    UWSF-Z.Umweltchem.Ökotox. 15 (2), 71 - 77
    full text (url)
to index

2002 (1)

  • Ulrich, M., Schulze, T., Leist, E., Glaß, B., Maier, M., Maier, D., Braunbeck, T., Hollert, H., (2002):
    Ökotoxikologische Untersuchung von Sedimenten und Schwebstoffen - Abschätzung des Gefährdungspotenzials für Trinkwasser und Korrelation verschiedener Expositionspfade (Acetonischer Extrakt, Natives Sediment) im Bakterienkontakttest und Fischeitest
    UWSF-Z.Umweltchem.Ökotox. 14 (3), 132 - 137
    full text (url)
to index

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