Research for the Environment

Dr. Tobias Schulze

Contact

Dr. Tobias Schulze
Research Scientist | Ecotoxicologist

Department Effect-Directed Analysis
Helmholtz Centre for
Environmental Research - UFZ
Permoserstraße 15
04318 Leipzig, Germany

phone +49 341 235 1083
fax +49 341 235 451083
tobias.schulze@ufz.de

Tobias Schulze

Research interests

  • Effect-directed analysis (EDA) of complex environmental samples
  • Nontarget screening of organic compounds in environmental samples using LC-MS/MS and GC-MS
  • Computer tools and statistical approaches for structure elucidation, toxicant identification and pattern recognition
  • Community driven mass spectra databases, open access data and data sharing
  • Sampling techniques and procedures for aquatic samples (water, sediments, suspended particulate matter, passive sampling)
  • Bioavailability of sediment-associated contaminants

Current projects

Finished projects

  • LPDA (Low Pressure Dialytic Analysis)-Laborgerät und –verfahren mit Hilfe spezieller semipermeabler Dialysemembranen zur Aufreinigung matrixbeeinflusster Substanzextrakte (AiF-FKZ KF0011005UL6)
  • MODELKEY Models for Assessing and Forecasting the Impact of Environmental Key Pollutants on Marine and Freshwater Ecosystems and Biodiversity (EU Contract-No. 511237 (GOCE))

Collaborations

Professional memberships

  • Society of Environmental Toxicology and Chemistry (SETAC)
  • Member of DIN working group “Sampling” of NA 119 Water Practice Standards Committee (German Institute for Standardisation)
  • Member of NORMAN working group 3 "Effect-directed analysis for hazardous pollutant identification"

Curriculum Vitae

12. - 21. August 2013

Guest core team member of the Joint Danube Survey 3

Nov. 2010

since 2007

Scientist at the Department of Effect-Directed Analysis, Helmholtz Centre for Environmental Research - UFZ

2000 - 2006

Scientist at the Department of Earth Sciences, Free University Berlin

1993 - 1999

Diploma in geography, geology and chemistry at Free University Berlin with focus on environmental chemistry and hydrogeology

Key publications (see below for full list of publications)

  • Hug, C., Ulrich, N., Schulze, T., Brack, W., Krauss, M., (2013):
    Identification of novel micropollutants in wastewater by a combination of suspect and nontarget screening
    Environ. Pollut. 184 , 25 - 32
    full text (url)
  • Lübcke-von Varel, U., Bataineh, M., Löffler, I., Schulze, T., Flückiger-Isler, S., Neca, J., Machala, M., Brack, W., Lohrmann, S., (2012):
    Identification and quantitative confirmation of dinitropyrenes and 3-nitrobenzanthrone as major mutagens in contaminated sediments
    Environ. Int. 44 (September 2012), 31 - 39
    full text (url)
  • Schulze, T., Magerl, R., Streck, G., Brack, W., (2012):
    Use of factorial design for the multivariate optimization of polypropylene membranes for the cleanup of environmental samples using the accelerated membrane-assisted cleanup approach
    J. Chromatogr. A 1225 , 26 - 36
    full text (url)
  • Schymanski, E.L., Gallampois, C.M.J., Krauss, M., Meringer, M., Neumann, S., Schulze, T., Wolf, S., Brack, W., (2012):
    Consensus structure elucidation combining GC/EI-MS, structure generation and calculated properties
    Anal. Chem. 84 (7), 3287 - 3295
    full text (url)
  • Schulze, T., Weiss, S., Schymanski, E., von der Ohe, P.C., Schmitt-Jansen, M., Altenburger, R., Streck, G., Brack, W., (2010):
    Identification of a phytotoxic photo-transformation product of diclofenac using effect-directed analysis
    Environ. Pollut. 158 (5), 1461 - 1466
    full text (url)
  • Brack, W., Bandow, N., Schwab, K., Schulze, T., Streck, G., (2009):
    Bioavailability in effect-directed analysis of organic toxicants in sediments
    Trac-Trends Anal. Chem. 28 (5), 543 - 549
    full text (url)
  • Kaisarevic, S., Lübcke-von Varel, U., Orcic, D., Streck, G., Schulze, T., Pogrmic, K., Teodorovic, I., Brack, W., Kovacevic, R., (2009):
    Effect-directed analysis of contaminated sediment from the wastewater canal in Pancevo industrial area, Serbia
    Chemosphere 77 (7), 907 - 913
    full text (url)
  • Brack, W., Schmitt-Jansen, M., Machala, M., Brix, R., Barceló, D., Schymanski, E., Streck, G., Schulze, T., (2008):
    How to confirm identified toxicants in effect-directed analysis
    Anal. Bioanal. Chem. 390 (8), 1959 - 1973
    full text (url)
  • Seiler, T.-B., Schulze, T., Hollert, H., (2008):
    The risk of altering soil and sediment samples upon extract preparation for analytical and bio-analytical investigations - a review
    Anal. Bioanal. Chem. 390 (8), 1975 - 1985
    full text (url)
  • Schulze, T., Ricking, M., Schöter-Kermani, C., Körner, A., Denner, H.D., Weinfurtner, K., Winkler, A., Pekdeger, A., (2007):
    The German Environmental Specimen Bank - Sampling, processing, and archiving sediment and suspended particulate matter
    J. Soils Sediments 7 (6), 361 - 367
    full text (url)

Full list of publications

Index:

2013 (3)
2012 (7)
2011 (5)
2010 (2)
2009 (4)
2008 (4)
2007 (5)
2005 (2)
2003 (3)
2002 (1)

You could use our publication index for further requests.

2013 (3)

  • Brack, W., Govender, S., Schulze, T., Krauss, M., Hu, M., Muz, M., Hollender, J., Schirmer, K., Schollee, J., Hidasi, A., Slobodnik, J., Rabova, Z., Ait-Aissa, S., Sonavane, M., Carere, M., Lamoree, M., Leonards, P., Tufi, S., Ouyang, X., Schriks, M., Thomas, K., de Almeida, A.C., Froment, J., Hammers-Wirtz, M., Ahel, M., Koprivica, S., Hollert, H., Seiler, T.-B., Di Paolo, C., Tindall, A., Spirhanzlova, P., (2013):
    EDA-EMERGE: an FP7 initial training network to equip the next generation of young scientists with the skills to address the complexity of environmental contamination with emerging pollutants
    Environmental Sciences Europe 25 , art. 18
    full text (pdf)
  • Grummt, T., Kuckelkorn, J., Bahlmann, A. A., Baumstark-Khan, C., Brack, W., Braunbeck, T., Feles, S., Gartiser, S., Glatt, H., Heinze, R., Hellweg, C.E., Hollert, H., Junek, R., Knauer, M., Kneib-Kissinger, B., Kramer, M., Krauss, M., Küster, E., Maletz, S., Meinl, W., Noman, A., Prantl, E.-M., Rabbow, E., Redelstein, R., Rettberg, P., Schadenboeck, W., Schmidt, C., Schulze, T., Seiler, T.-B., Spitta, L., Stengel, D., Waldmann, P., Eckhardt, A., (2013):
    Tox-Box: securing drops of life - an enhanced health-related approach for risk assessment of drinking water in Germany. Tox-Box: die Tropfen des Lebens bewahren - gesundheitsbasierte Risikobewertung für Trinkwasser in Deutschland
    Environmental Sciences Europe 25 , art. 27
    full text (pdf)
  • Hug, C., Ulrich, N., Schulze, T., Brack, W., Krauss, M., (2013):
    Identification of novel micropollutants in wastewater by a combination of suspect and nontarget screening
    Environ. Pollut. 184 , 25 - 32
    full text (url)
to index

2012 (7)

  • Higley, E., Grund, S., Jones, P.D., Schulze, T., Seiler, T.-B., Lübcke-von Varel, U., Brack, W., Wölz, J., Zielke, H., Giesy, J.P., Hollert, H., Hecker, M., (2012):
    Endocrine disrupting, mutagenic, and teratogenic effects of upper Danube River sediments using effect-directed analysis
    Environ. Toxicol. Chem. 31 (5), 1053 - 1062
    full text (url)
  • Lübcke-von Varel, U., Bataineh, M., Löffler, I., Schulze, T., Flückiger-Isler, S., Neca, J., Machala, M., Brack, W., Lohrmann, S., (2012):
    Identification and quantitative confirmation of dinitropyrenes and 3-nitrobenzanthrone as major mutagens in contaminated sediments
    Environ. Int. 44 (September 2012), 31 - 39
    full text (url)
  • Schulze, T., Brack, W., Walz, K.-H., (2012):
    Verfahren und Vorrichtung zur Festphasenextraktion aus einer Flüssigkeit
    Europäisches Patentamt, München
  • Schulze, T., Magerl, R., Streck, G., Brack, W., (2012):
    Use of factorial design for the multivariate optimization of polypropylene membranes for the cleanup of environmental samples using the accelerated membrane-assisted cleanup approach
    J. Chromatogr. A 1225 , 26 - 36
    full text (url)
  • Schulze, T., Schymanski, E., Stravs, M., Neumann, S., Krauss, M., Singer, H., Hug, C., Gallampois, C., Hollender, J., Slobodnik, J., Brack, W., (2012):
    NORMAN MassBank: Towards a community-driven, open-access accurate mass spectral database for the identification of emerging pollutants
    Norman Bulletin 2012/3
    NORMAN Network, p. 9 - 11
  • Schulze, T., Seiler, T.-B., Streck, G., Braunbeck, T., Hollert, H., (2012):
    Comparison of different exhaustive and biomimetic extraction techniques for chemical and biological analysis of polycyclic aromatic compounds in river sediments
    J. Soils Sediments 12 (9), 1419 - 1434
    full text (url)
  • Schymanski, E.L., Gallampois, C.M.J., Krauss, M., Meringer, M., Neumann, S., Schulze, T., Wolf, S., Brack, W., (2012):
    Consensus structure elucidation combining GC/EI-MS, structure generation and calculated properties
    Anal. Chem. 84 (7), 3287 - 3295
    full text (url)
to index

2011 (5)

  • dos Anjos, N.A., Schulze, T., Brack, W., Val, A.L., Schirmer, K., Scholz, S., (2011):
    Identification and evaluation of cyp1a transcript expression in fish as molecular biomarker for petroleum contamination in tropical fresh water ecosystems
    Aquat. Toxicol. 103 (1-2), 46 - 52
    full text (url)
  • Schulze, T., Streck, G., Paschke, A., (2011):
    Sampling and conservation
    In: Frimmel, F.H., (ed.)
    Treatise on Water Science Vol. 3: Aquatic Chemistry and Microbiology
    3
    Elsevier Science, Oxford, p. 131 - 152
    full text (url)
  • Schymanski, E., Schulze, T., Hermanns, J., Brack, W., (2011):
    Computer tools for structure elucidation in effect-directed analysis
    In: Brack, W., (ed.)
    Effect-directed analysis of complex environmental contamination
    Handbook of Environmental Chemistry Series 15
    Springer, Berlin, Heidelberg, p. 167 - 198
    full text (url)
  • Wölz, J., Grosshans, K., Streck, G., Schulze, T., Rastall, A., Erdinger, L., Brack, W., Fleig, M., Kühlers, D., Braunbeck, T., Hollert, H., (2011):
    Estrogen receptor mediated activity in bankside groundwater, with flood suspended particulate matter and floodplain soil – an approach combining tracer substance, bioassay and target analysis
    Chemosphere 85 (5), 717 - 723
    full text (url)
  • Wölz, J., Schulze, T., Lübcke-von Varel, U., Fleig, M., Reifferscheid, G., Brack, W., Kühlers, D., Braunbeck, T., Hollert, H., (2011):
    Investigation on soil contamination at recently inundated and non-inundated sites
    J. Soils Sediments 11 (1), 82 - 92
    full text (url)
to index

2010 (2)

  • Schulze, T., Weiss, S., Schymanski, E., von der Ohe, P.C., Schmitt-Jansen, M., Altenburger, R., Streck, G., Brack, W., (2010):
    Identification of a phytotoxic photo-transformation product of diclofenac using effect-directed analysis
    Environ. Pollut. 158 (5), 1461 - 1466
    full text (url)
  • Wölz, J., Fleig, M., Schulze, T., Maletz, S., Lübcke-von Varel, U., Reifferscheid, G., Kühlers, D., Braunbeck, T., Brack, W., Hollert, H., (2010):
    Impact of contaminants bound to suspended particulate matter in the context of flood events
    J. Soils Sediments 10 (6), 1174 - 1185
    full text (url)
to index

2009 (4)

  • Brack, W., Bandow, N., Schwab, K., Schulze, T., Streck, G., (2009):
    Identifizierung toxischer Verbindungen in Sedimenten: Ansätze zur Integration von Wirkung und Bioverfügbarkeit
    UWSF-Z.Umweltchem.Ökotox. 21 (3), 240 - 244
    full text (url)
  • Brack, W., Bandow, N., Schwab, K., Schulze, T., Streck, G., (2009):
    Bioavailability in effect-directed analysis of organic toxicants in sediments
    Trac-Trends Anal. Chem. 28 (5), 543 - 549
    full text (url)
  • Hollert, H., Claus, E., Ahlf, W., Brack, W., Braunbeck, T., Hudjetz, S., Manz, W., Ratte, H.T., Reifferscheid, G., Schäffer, A., Schulze, T., Schwarzbauer, J., Heininger, P., (2009):
    Über die Notwendigkeit der wirkungsorientierten Analytik in einer umfassenden Wasserforschung
    UWSF-Z.Umweltchem.Ökotox. 21 (3), 235 - 237
    full text (url)
  • Kaisarevic, S., Lübcke-von Varel, U., Orcic, D., Streck, G., Schulze, T., Pogrmic, K., Teodorovic, I., Brack, W., Kovacevic, R., (2009):
    Effect-directed analysis of contaminated sediment from the wastewater canal in Pancevo industrial area, Serbia
    Chemosphere 77 (7), 907 - 913
    full text (url)
to index

2008 (4)

  • Brack, W., Schmitt-Jansen, M., Machala, M., Brix, R., Barceló, D., Schymanski, E., Streck, G., Schulze, T., (2008):
    How to confirm identified toxicants in effect-directed analysis
    Anal. Bioanal. Chem. 390 (8), 1959 - 1973
    full text (url)
  • Seiler, T.-B., Schulze, T., Hollert, H., (2008):
    The risk of altering soil and sediment samples upon extract preparation for analytical and bio-analytical investigations - a review
    Anal. Bioanal. Chem. 390 (8), 1975 - 1985
    full text (url)
  • Streck, G., Schulze, T., Brack, W., (2008):
    Accelerated membrane-assisted clean-up as a tool for the clean-up of extracts from biological tissues
    J. Chromatogr. A 1196-1197 , 33 - 40
    full text (url)
  • Streck, G., Schulze, T., Brack, W., (2008):
    Accelerated Membrane Assisted Clean-up: Eine leistungsfähige Methode zur Aufreinigung matrixbehafteter Extrakte
    LC-GC Ads März/April 2008 , 6 - 10
to index

2007 (5)

  • Rüdel, H., Bester, K., Eisenträger, A., Franzaring, J., Haarich, M., Köhler, J., Körner, W., Oehlmann, J., Paschke, A., Ricking, M., Schröder, W., Schröter-Kermani, C., Schulze, T., Schwarzbauer, J., Theobald, N., von der Trenck, T., Wagner, G., Wiesmüller, G.A., (2007):
    Positionspapier zum stoffbezogenen Umweltmonitoring (Teil 2 von 2)
    Gesellschaft Deutscher Chemiker / Mitteilungen der Fachgruppe Umweltchemie und Ökotoxikologie 13 (3), 72 - 79
  • Rüdel, H., Bester, K., Eisenträger, A., Franzaring, J., Haarich, M., Köhler, J., Körner, W., Oehlmann, J., Paschke, A., Ricking, M., Schröder, W., Schröter-Kermani, C., Schulze, T., Schwarzbauer, J., Theobald, N., von der Trenck, T., Wagner, G., Wiesmüller, G.A., (2007):
    Positionspapier zum stoffbezogenen Umweltmonitoring (Teil 1 von 2)
    Gesellschaft Deutscher Chemiker / Mitteilungen der Fachgruppe Umweltchemie und Ökotoxikologie 13 (2), 34 - 41
  • Rüdel, H., Bester, K., Eisenträger, A., Franzaring, J., Haarich, M., Köhler, J., Körner, W., Oehlmann, J., Paschke, A., Ricking, M., Schröder, W., Schröter-Kermani, C., Schulze, T., Schwarzbauer, J., Theobald, N., von der Trenck, T., Wagner, G., Wiesmüller, G.A., (2007):
    Stoffbezogenes Umweltmonitoring
    In: Wichmann, H.-E., Schlipköter, H.W., Fülgraff, G., (Hrsg.)
    Handbuch der Umweltmedizin
    37. Erg.lfg. 10/07
    ecomed, Landsberg am Lech, S. IV-7.1
  • Schulze, T., Ricking, M., Pekdeger, A., Winkler, A., (2007):
    Validierung der SOPs ?Sediment und Schwebstoffe" unter Routinebedingungen - Abschlussbericht an das Umweltbundesamt (Dessau) (FKZ 301 02 018)
    Freie Universität Berlin, Berlin, 64 S.
  • Schulze, T., Ricking, M., Schöter-Kermani, C., Körner, A., Denner, H.D., Weinfurtner, K., Winkler, A., Pekdeger, A., (2007):
    The German Environmental Specimen Bank - Sampling, processing, and archiving sediment and suspended particulate matter
    J. Soils Sediments 7 (6), 361 - 367
    full text (url)
to index

2005 (2)

  • Hallare, A.V., Kosmehl, T., Schulze, T., Hollert, H., Köhler, H.-R., Triebskorn, R., (2005):
    Assessing contamination levels of Laguna Lake sediments (Philippines) using a contact assay with zebrafish (Danio rerio) embryos
    Sci. Total Environ. 347 (1-3), 254 - 271
    full text (url)
  • Schulze, T., Ricking, M., Pekdeger, A., Winkler, A., (2005):
    Entwicklung einer Verfahrensrichtlinie Sedimente und Schwebstoffe - Abschlussbericht an das Umweltbundesamt (Dessau) (FKZ 301 02 013)
    Freie Universität Berlin, Berlin, 128 S.
to index

2003 (3)

  • Hollert, H., Ulrich, M., Schulze, T., Terytze, K., Braunbeck, T., (2003):
    Ökotoxikologische Bewertung von Rheinsedimenten und Schwebstoffen in Überflutungsgebieten
    Universität Heidelberg, Institut für Zoologie, Heidelberg, 185 S.
  • Ricking, M., Schulze, T., (2003):
    Deep-freeze sampling methods for soft sediments
    In: Locat, J., Cloutier, R.G., Chaney, R., Demars, K., (eds.)
    Contaminated sediments: characterization, evaluation, mitigation/restoration, and management strategy performance
    ASTM Special Technical Publication 1442
    ASTM International, West Conshohocken, PA, p. 28 - 35
  • Schulze, T., Wetterauer, B., Schwarzbauer, J., Hollert, H., Braunbeck, T., Ricking, M., (2003):
    DDT und Metabolite in Sedimenten Berliner Gewässer - Vorkommen, Analytik und Schädigungspotenzial
    UWSF-Z.Umweltchem.Ökotox. 15 (2), 71 - 77
    full text (url)
to index

2002 (1)

  • Ulrich, M., Schulze, T., Leist, E., Glaß, B., Maier, M., Maier, D., Braunbeck, T., Hollert, H., (2002):
    Ökotoxikologische Untersuchung von Sedimenten und Schwebstoffen - Abschätzung des Gefährdungspotenzials für Trinkwasser und Korrelation verschiedener Expositionspfade (Acetonischer Extrakt, Natives Sediment) im Bakterienkontakttest und Fischeitest
    UWSF-Z.Umweltchem.Ökotox. 14 (3), 132 - 137
    full text (url)
to index