Endpoints in REACH
For the registration of chemicals within REACH, information regarding the following endpoints has to be submitted in the technical dossier.
For more details and dependence on the tonnage manufactured or imported see the following 
REACH overview.
Physicochemical information
7.1 State of the substance at 20 °C and 101,3 kPa
7.2 Melting/freezing point
7.3 Boiling point
7.4 Relative density
7.5 Vapour pressure
7.6 Surface tension
7.7 Water solubility
7.8 Partition coefficient n-octanol/water
7.9 Flash-point
7.10 Flammability
7.11 Explosive properties
7.12 Self-ignition temperature
7.13 Oxidising properties
7.14 Granulometry
7.15. Stability in organic solvents and identity of relevant degradation products
7.16. Dissociation constant
7.17. Viscosity
Toxicological information
8.1 Skin irritation or skin corrosion
8.1.1 In vivo skin irritation
8.2 Eye irritation
8.2.2 In vivo eye irritation
8.3 Skin sensitisation
8.4 Mutagenicity
8.4.1 In vitro gene mutation study in bacteria
8.4.2 In vitro cytogenicity study in mammalian cells or in vitro micronucleus study
8.4.3 In vitro gene mutation study in mammalian cells
8.5 Acute toxicity
8.5.1 By oral route
8.5.2. By inhalation
8.5.3. By dermal route
8.6. Repeated dose toxicity
8.6.1. Short-term repeated dose toxicity study (28 days)
8.6.2. Sub-chronic toxicity study (90-day)
8.6.3. Long-term repeated toxicity study (≥ 12 months)
8.6.4. Further repeated dose toxicity studies
8.7. Reproductive toxicity
8.7.1. Screening for reproductive/ developmental toxicity
8.7.2. Pre-natal developmental toxicity study
8.7.2. Developmental toxicity study
8.7.3. Two-generation reproductive toxicity study
8.8. Toxicokinetics
8.8.1. Assessment of the toxicokinetic behaviour of the substance to the extent that can be derived from the relevant available information
8.9. Carcenogenicity
8.9.1. Carcinogenicity study
Ecotoxicological information
9.1 Aquatic toxicity
9.1.1 Short-term toxicity testing on invertebrates (preferred species Daphnia)
9.1.2 Growth inhibition study aquatic plants (algae preferred)
9.1.3. Short-term toxicity testing on fish
9.1.4. Activated sludge respiration inhibition testing
9.1.5. Long-term toxicity testing on invertebrates (preferred species Daphnia)
9.1.6. Long-term toxicity testing on fish:
9.1.6.1. Fish early-life stage (FELS) toxicity test
9.1.6.2. Fish short-term toxicity test on embryo and sac-fry stages
9.1.6.3. Fish, juvenile growth test
9.2 Degradation
9.2.1 Biotic
9.2.1.1 Ready biodegradability
9.2.1.2. Simulation testing on ultimate degradation in surface water
9.2.1.3. Soil simulation testing (for substances with a high potential for adsorption to soil)
9.2.1.4. Sediment simulation testing (for substances with a high potential for adsorption to sediment)
9.2.2. Abiotic
9.2.2.1. Hydrolysis as a function of pH.
9.2.3. Identification of degradation products
9.3. Fate and behaviour in the environment
9.3.1. Adsorption/desorption screening
9.3.2. Bioaccumulation in aquatic species, preferably fish
9.3.3. Further information on adsorption/desorption
9.3.4. Further information on the environmental fate and behaviour of the substance and/or degradation products
9.4. Effects on terrestrial organisms
9.4.1. Short-term toxicity to invertebrates
9.4.2. Effects on soil micro-organisms
9.4.3. Short-term toxicity to plants
9.4.4. Long-term toxicity testing on invertebrates
9.4.6. Long-term toxicity testing on plants
9.5 Effects on sediment organisms
9.5.1. Long-term toxicity to sediment organisms
9.6. Toxicity to birds
9.6.1. Long-term or reproductive toxicity to birds
