PD Dr. Werner Brack

PD Dr. Werner Brack
Foto: Sebastian Wiedling/UFZ

Address:
Permoserstr. 15
04318 Leipzig
Germany

Building: 6.0
Room: 328
Phone +49 341 235 1531

PD Dr. Werner Brack

Curriculum Vitae

since 2005

Head of the Department of Effect-Directed Analysis at the Helmholtz Centre for Environmental Research - UFZ

1997 - 2005

Scientist at the Department of Chemical Ecotoxicology at the Helmholtz Centre for Environmental Research - UFZ

1992 - 1996

PhD thesis at the University of Bayreuth, topic: "Ecotoxicological assessment of volatile components of landfill leachates"

1992

Diploma in Geo-Ecology at the University of Bayreuth

Key research areas

  • Effect-Directed Analysis: Toxicant identification in complex mixtures including water, sediments, tissue, blood and urine. This includes the development of new separation techniques, the application and evaluation of bioassays and a broad array of chemical analytical techniques.
  • Bioavailability of toxicants and its operationalization as a prioritisation criteria in effect-directed analysis, e.g. of contaminated sediments including extraction techniques, passive dosing and prediction models for chemicals uptake
  • Structure elucidation of unknown environmental compounds combining chemical analysis with the prediction chromatographic retention, mass spectrometric fragmentation, toxicity e.c.t.
  • Assessment and prioritisation of contamination in aquatic ecosystems and the establishment of cause-effect relationships between chemicals and observable effects, particularly in the context of water quality management and the implementation of the EU Water Framework Directive.

Boards and memberships

  • Member of the “Network of reference laboratories and related organizations for monitoring and bio-monitoring of emerging environmental pollutants” (NORMAN). Active role in WG on Substance Prioritization. Coordinator of WG on Effect-Directed Analysis
  • Member of Scientific Committee of the EU-Project GlobAqua on the analyze of the effects of multiple stressors on biodiversity and functioning of aquatic ecosystems
  • Member of the Advisory Board of the Centre for Future Chemical Risk Assessment and Management Strategies (FRAM) at the University of Gothenburg, Sweden
  • Member of the Society for Environmental Toxicology and Chemistry (SETAC) and the SETAC Sediment Advisory Board. Member of Scientific Board of SETAC Europe Conference 2015 in Barcelona

Current Projects

since 2017

NaToxAq (Natural Toxins and Drinking Water Quality – From Source to Tap). EU Horizon 2020 European Training Network ETN (No 722493)

since 2013

SOLUTIONS for present and future emerging pollutants in land and water resources management. European Collaborative Project. Coordinator. (FP7-603437)

Completed Projects

2012 - 2015

TOX-BOX (Gefährdungsbasiertes Risikomanagement für anthropogene Spurenstoffe zur Sicherung der Trinkwasserversorgung); BMBF

 2011 - 2015

EDA-EMERGE (Innovative biodiagnosis meets chemical structure elucidation – Novel tools in effect-directed analysis to support the identification and monitoring of emerging toxicants on a European scale) European Marie Curie Initial Training Network. Coordinator (PITN-GA-2011-290100)

2011 - 2014

Large-Volume Solid Phase Extraction (LVSPE) technique and sampling device for automated time- and volume-proportional sampling of water samples using solid-phase extraction, AiF KF2081009MK0

2011 - 2014

Concept development for non-target screening of human samples and identification of environmentally relevant compounds as a basis for the development of new human biomonitoring methods, Umweltbundesamt Z6-55 410-49/2

2007 - 2009

 LPDA (Low Pressure Dialytic Analysis)-instrument and technique for the clean-up of matrix-impacted extracts using semipermeable dialysis membranes. Cooperation project AiF 2007-2009

2006 - 2010

KEYBIOEFFECTS (Cause-Effect Relationships of Key Pollutants on the European Rivers Biodiversity); European Marie Curie Research Training Network (MRTN-CT-2006-035695)

2006 - 2009

RISKBASE (Risk-Based Management of European River Basins); European Coordination Action (GOCE 036938). Work package leader for  Risk Assessment

2005 - 2010

MODELKEY (Models for Assessing and Forecasting the Impact of Environmental Key Pollutants on Freshwater and Marine Ecosystems); European Integrated Project, Coordinator (511237 (GOCE)

Publications

Inhalt:

2017 (13)
2016 (9)
2015 (19)
2014 (11)
2013 (8)
2012 (11)
2011 (18)
2010 (12)
2009 (14)
2008 (8)
2007 (5)
2006 (5)
2005 (9)
2004 (2)
2003 (7)
2002 (4)
2000 (6)
1999 (3)
1998 (6)
1997 (1)

Weiterführende Recherchen können Sie in unserem Publikationsverzeichnis durchführen.

2017 (13)

  • Brack, W., Dulio, V., Ågerstrand, M., Allan, I., Altenburger, R., Brinkmann, M., Bunke, D., Burgess, R.M., Cousins, I., Escher, B.I., Hernández, F.J., Hewitt, L.M., Hilscherová, K., Hollender, J., Hollert, H., Kase, R., Klauer, B., Lindim, C., López Herráez, D., Miège, C., Munthe, J., O'Toole, S., Posthuma, L., Rüdel, H., Schäfer, R.B., Sengl, M., Smedes, F., van de Meent, D., van den Brink, P., van Gils, J., van Wezel, A.P., Dick Vethaak, A., Vermeirssen, E., von der Ohe, P.C., Vrana, B., (2017):
    Towards the review of the European Union Water Framework Directive: Recommendations for more efficient assessment and management of chemical contamination in European surface water resources
    Sci. Total Environ. 576 , 720 - 737
    Volltext (URL)
  • Escher, B.I., Hackermüller, J., Polte, T., Scholz, S., Aigner, A., Altenburger, R., Böhme, A., Bopp, S.K., Brack, W., Busch, W., Chadeau-Hyam, M., Covaci, A., Eisenträger, A., Galligan, J.J., Garcia-Reyero, N., Hartung, T., Hein, M., Herberth, G., Jahnke, A., Kleinjans, J., Klüver, N., Krauss, M., Lamoree, M., Lehmann, I., Luckenbach, T., Miller, G.W., Müller, A., Phillips, D.H., Reemtsma, T., Rolle-Kampczyk, U., Schüürmann, G., Schwikowski, B., Tan, Y.-M., Trump, S., Walter-Rohde, S., Wambaugh, J.F., (2017):
    From the exposome to mechanistic understanding of chemical-induced adverse effects
    Environ. Int. 99 , 97 - 106
    Volltext (URL)
  • Inostroza, P.A., Massei, R., Wild, J., Krauss, M., Brack, W., (2017):
    Chemical activity and distribution of emerging pollutants: insights from a multi-compartment analysis of a freshwater system
    Environ. Pollut. 231, Part 1 , 339 - 347
    Volltext (URL)
  • König, M., Escher, B.I., Neale, P.A., Krauss, M., Hilscherová, K., Novák, J., Teodorović, I., Schulze, T., Seidensticker, S., Hashmi, M.A.K., Ahlheim, J., Brack, W., (2017):
    Impact of untreated wastewater on a major European river evaluated with a combination of in vitro bioassays and chemical analysis
    Environ. Pollut. 220 (Part B), 1220 - 1230
    Volltext (URL)
  • Kurth, D., Krauss, M., Schulze, T., Brack, W., (2017):
    Measuring the internal concentration of volatile organic compounds in small organisms using micro-QuEChERS coupled to LVI–GC–MS/MS
    Anal. Bioanal. Chem. 409 (25), 6041 - 6052
    Volltext (URL)
  • Kurth, D., Lips, S., Massei, R., Krauss, M., Luckenbach, T., Schulze, T., Brack, W., (2017):
    The impact of chemosensitisation on bioaccumulation and sediment toxicity
    Chemosphere 186 , 652 - 659
    Volltext (URL)
  • Munthe, J., Brorström-Lundén, E., Rahmberg, M., Posthuma, L., Altenburger, R., Brack, W., Bunke, D., Engelen, G., Gawlik, B.M., van Gils, J., López Herráez, D., Rydberg, T., Slobodnik, J., van Wezel, A., (2017):
    An expanded conceptual framework for solution-focused management of chemical pollution in European waters
    Environmental Sciences Europe 29 , art. 13
    Volltext (URL)
  • Muz, M., Dann, J.P., Jäger, F., Brack, W., Krauss, M., (2017):
    Identification of mutagenic aromatic amines in river samples with industrial wastewater impact
    Environ. Sci. Technol. 51 (8), 4681 - 4688
    Volltext (URL)
  • Muz, M., Krauss, M., Kutsarova, S., Schulze, T., Brack, W., (2017):
    Mutagenicity in surface waters: synergistic effects of carboline alkaloids and aromatic amines
    Environ. Sci. Technol. 51 (3), 1830 - 1839
    Volltext (URL)
  • Muz, M., Ost, N., Kühne, R., Schüürmann, G., Brack, W., Krauss, M., (2017):
    Nontargeted detection and identification of (aromatic) amines in environmental samples based on diagnostic derivatization and LC-high resolution mass spectrometry
    Chemosphere 166 , 300 - 310
    Volltext (URL)
  • Schulze, T., Ahel, M., Ahlheim, J., Aït-Aïssa, S., Brion, F., Di Paolo, C., Froment, J., Hidasi, A.O., Hollender, J., Hollert, H., Hu, M., Kloß, A., Koprivica, S., Krauss, M., Muz, M., Oswald, P., Petre, M., Schollée, J.E., Seiler, T.-B., Shao, Y., Slobodnik, J., Sonavane, M., Suter, M.J.-F., Tollefsen, K.E., Tousova, Z., Walz, K.-H., Brack, W., (2017):
    Assessment of a novel device for onsite integrative large-volume solid phase extraction of water samples to enable a comprehensive chemical and effect-based analysis
    Sci. Total Environ. 581–582 , 350 - 358
    Volltext (URL)
  • Tousova, Z., Oswald, P., Slobodnik, J., Blaha, L., Muz, M., Hu, M., Brack, W., Krauss, M., Di Paolo, C., Tarcai, Z., Seiler, T.-B., Hollert, H., Koprivica, S., Ahel, M., Schollée, J.E., Hollender, J., Suter, M.J.-F., Hidasi, A.O., Schirmer, K., Sonavane, M., Ait-Aissa, S., Creusot, N., Brion, F., Froment, J., Almeida, A.C., Thomas, K., Tollefsen, K.E., Tufi, S., Ouyang, X., Leonards, P., Lamoree, M., Torrens, V.O., Kolkman, A., Schriks, M., Spirhanzlova, P., Tindall, A., Schulze, T., (2017):
    European demonstration program on the effect-based and chemical identification and monitoring of organic pollutants in European surface waters
    Sci. Total Environ. 601-602 , 1849 - 1868
    Volltext (URL)
  • Välitalo, P., Massei, R., Heiskanen, I., Behnisch, P., Brack, W., Tindall, A.J., Du Pasquier, D., Küster, E., Mikola, A., Schulze, T., Sillanpää, , (2017):
    Effect-based assessment of toxicity removal during wastewater treatment
    Water Res.
    Volltext (URL)
zum Inhalt

2016 (9)

  • Brack, W., Ait-Aissa, S., Burgess, R.M., Busch, W., Creusot, N., Di Paolo, C., Escher, B.I., Hewitt, L.M., Hilscherova, K., Hollender, J., Hollert, H., Jonker, W., Kool, J., Lamoree, M., Muschket, M., Neumann, S., Rostkowski, P., Ruttkies, C., Schollee, J., Schymanski, E.L., Schulze, T., Seiler, T.-B., Tindall, A.J., De Aragão Umbuzeiro, G., Vrana, B., Krauss, M., (2016):
    Effect-directed analysis supporting monitoring of aquatic environments — An in-depth overview
    Sci. Total Environ. 544 , 1073 - 1118
    Volltext (URL)
  • Deutschmann, B., Kolarevic, S., Brack, W., Kaisarevic, S., Kostic, J., Kracun-Kolarevic, M., Liska, I., Paunovic, M., Seiler, T.-B., Shao, Y., Sipos, S., Slobodnik, J., Teodorovic, I., Vukovic-Gacic, B., Hollert, H., (2016):
    Longitudinal profile of the genotoxic potential of the River Danube on erythrocytes of wild common bleak (Alburnus alburnus) assessed using the comet and micronucleus assay
    Sci. Total Environ. 573 , 1441 - 1449
    Volltext (URL)
  • Di Paolo, C., Kirchner, K., Balk, F.G.P., Muschket, M., Brack, W., Hollert, H., Seiler, T.-B., (2016):
    Downscaling procedures reduce chemical use in androgen receptor reporter gene assay
    Sci. Total Environ. 571 , 826 - 833
    Volltext (URL)
  • Di Paolo, C., Ottermanns, R., Keiter, S., Ait-Aissa, S., Bluhm, K., Brack, W., Breitholtz, M., Buchinger, S., Carere, M., Chalon, C., Cousin, X., Dulio, V., Escher, B.I., Hamers, T., Hilscherová, K., Jarque, S., Jonas, A., Maillot-Marechal, C., Marneffe, Y., Nguyen, M.T., Pandard, P., Schifferli, A., Schulze, T., Seidensticker, S., Seiler, T.-B., Tang, J., van der Oost, J., Vermeirssen, E., Zounková, R., Zwart, N., Hollert, H., (2016):
    Bioassay battery interlaboratory investigation of emerging contaminants in spiked water extracts – Towards the implementation of bioanalytical monitoring tools in water quality assessment and monitoring
    Water Res. 104 , 473 - 484
    Volltext (URL)
  • Hu, M., Krauss, M., Brack, W., Schulze, T., (2016):
    Optimization of LC-Orbitrap-HRMS acquisition and MZmine 2 data processing for nontarget screening of environmental samples using design of experiments
    Anal. Bioanal. Chem. 408 (28), 7905 - 7915
    Volltext (URL)
  • Inostroza, P.A., Vera-Escalona, I., Wicht, A.-J., Krauss, M., Brack, W., Norf, H., (2016):
    Anthropogenic stressors shape genetic structure: insights from a model freshwater population along a land use gradient
    Environ. Sci. Technol. 50 (20), 11346 - 11356
    Volltext (URL)
  • Inostroza, P.A., Wicht, A.-J., Huber, T., Nagy, C., Brack, W., Krauss, M., (2016):
    Body burden of pesticides and wastewater-derived pollutants on freshwater invertebrates: Method development and application in the Danube River
    Environ. Pollut. 214 , 77 - 85
    Volltext (URL)
  • Tuikka, A.I., Leppänen, M.T., Akkanen, J., Sormunen, A.J., Leonards, P.E.G., van Hattum, B., van Vliet, L.A., Brack, W., Smedes, F., Kukkonen, J.V.K., (2016):
    Predicting the bioaccumulation of polyaromatic hydrocarbons and polychlorinated biphenyls in benthic animals in sediments
    Sci. Total Environ. 563–564 , 396 - 404
    Volltext (URL)
  • Xiao, H., Krauss, M., Floehr, T., Yan, Y., Bahlmann, A., Eichbaum, K., Brinkmann, M., Zhang, X., Yuan, X., Brack, W., Hollert, H., (2016):
    Effect-directed analysis of aryl hydrocarbon receptor agonists in sediments from the Three Gorges Reservoir, China
    Environ. Sci. Technol. 50 (20), 11319 - 11328
    Volltext (URL)
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2015 (19)

  • Altenburger, R., Ait-Aissa, S., Antczak, P., Backhaus, T., Barceló, D., Seiler, T.-B., Brion, F., Busch, W., Chipman, K., López de Alda, M., De Aragão Umbuzeiro, G., Escher, B.I., Falciani, F., Faust, M., Focks, A., Hilscherova, K., Hollender, J., Hollert, H., Jäger, F., Jahnke, A., Kortenkamp, A., Krauss, M., Lemkine, G.F., Munthe, J., Neumann, S., Schymanski, E.L., Scrimshaw, M., Segner, H., Slobodnik, J., Smedes, F., Kughathas, S., Teodorovic, I., Tindall, A.J., Tollefsen, K.E., Walz, K.-H., Williams, T.D., van den Brink, P.J., van Gils, J., Vrana, B., Zhang, X., Brack, W., (2015):
    Future water quality monitoring — Adapting tools to deal with mixtures of pollutants in water resource management
    Sci. Total Environ. 512-513 , 540 - 551
    Volltext (URL)
  • Bahlmann, A., Lochen, T., Schulze, T., Kirschner, A., Brack, W., Schneider, R.J., Krauss, M., (2015):
    Chemical and immunochemical analysis of anthropogenic markers and contaminants
    In: Liška, I., Wagner, F., Sengl, M., Deutsch, K., Slobodník, J., (eds.)
    Joint Danube Survey 3 : a comprehensive analysis of Danube water quality
    International Commission for the Protection of the Danube River (ICPDR), Wien, p. 277 - 283
  • Brack, W., (2015):
    The Challenge: Prioritization of emerging pollutants
    Environ. Toxicol. Chem. 34 (10), 2181
    Volltext (URL)
  • Brack, W., Altenburger, R., Schüürmann, G., Krauss, M., López Herráez, D., van Gils, J., Slobodnik, J., Munthe, J., Gawlik, B.M., van Wezel, A., Schriks, M., Hollender, J., Tollefsen, K.E., Mekenyan, O., Dimitrov, S., Bunke, D., Cousins, I., Posthuma, L., van den Brink, P.J., López de Alda, M., Barceló, D., Faust, M., Kortenkamp, A., Scrimshaw, M., Ignatova, S.N., Engelen, G., Massmann, G., Lemkine, G., Teodorovic, I., Walz, K.-H., Dulio, V., Jonker, M.T.O., Jäger, F., Chipman, K., Falciani, F., Liska, I., Rooke, D., Zhang, X., Hollert, H., Vrana, B., Hilscherova, K., Kramer, K., Neumann, S., Hammerbacher, R., Backhaus, T., Mack, J., Segner, H., Escher, B., De Aragão Umbuzeiro, G., (2015):
    The SOLUTIONS project: challenges and responses for present and future emerging pollutants in land and water resources management
    Sci. Total Environ. 503-504 , 22 - 31
    Volltext (URL)
  • Di Paolo, C., Seiler, T.-B., Keiter, S., Hu, M., Muz, M., Brack, W., Hollert, H., (2015):
    The value of zebrafish as an integrative model in effect-directed analysis - a review
    Environmental Sciences Europe 27 , art. 8
    Volltext (URL)
  • Gallampois, C.M.J., Schymanski, E.L., Krauss, M., Ulrich, N., Bataineh, M., Brack, W., (2015):
    Multicriteria approach to select polyaromatic river mutagen candidates
    Environ. Sci. Technol. 49 (5), 2959 - 2968
    Volltext (URL)
  • Hug, C., Krauss, M., Nüsser, L., Hollert, H., Brack, W., (2015):
    Metabolic transformation as a diagnostic tool for the selection of candidate promutagens in effect-directed analysis
    Environ. Pollut. 196 , 114 - 124
    Volltext (URL)
  • Hug, C., Sievers, M., Ottermanns, R., Hollert, H., Brack, W., Krauss, M., (2015):
    Linking mutagenic activity to micropollutant concentrations in wastewater samples by partial least square regression and subsequent identification of variables
    Chemosphere 138 , 176 - 182
    Volltext (URL)
  • Hug, C., Zhang, X., Guan, M., Krauss, M., Bloch, R., Schulze, T., Reinecke, T., Hollert, H., Brack, W., (2015):
    Microbial reporter gene assay as a diagnostic and early warning tool for the detection and characterization of toxic pollution in surface waters
    Environ. Toxicol. Chem. 34 (11), 2523 - 2532
    Volltext (URL)
  • Kaisarevic, S., Dakic, V., Hrubik, J., Glisic, B., Lübcke-von Varel, U., Pogrmic-Majkic, K., Fa, S., Teodorovic, I., Brack, W., Kovacevic, R., (2015):
    Differential expression of CYP1A1 and CYP1A2 genes in H4IIE rat hepatoma cells exposed to TCDD and PAHs
    Environ. Toxicol. Pharmacol. 39 (1), 358 - 368
    Volltext (URL)
  • Kurth, D., Brack, W., Luckenbach, T., (2015):
    Is chemosensitisation by environmental pollutants ecotoxicologically relevant?
    Aquat. Toxicol. 167 , 134 - 140
    Volltext (URL)
  • Neale, P.A., Ait-Aissa, S., Brack, W., Creusot, N., Denison, M.S., Deutschmann, B., Hilscherová, K., Hollert, H., Krauss, M., Novák, J., Schulze, T., Seiler, T.-B., Serra, H., Shao, Y., Escher, B.I., (2015):
    Linking in vitro effects and detected organic micropollutants in surface water using mixture-toxicity modeling
    Environ. Sci. Technol. 49 (24), 14614 - 14624
    Volltext (URL)
  • Plassmann, M.M., Brack, W., Krauss, M., (2015):
    Extending analysis of environmental pollutants in human urine towards screening for suspected compounds
    J. Chromatogr. A 1394 , 18 - 25
    Volltext (URL)
  • Plassmann, M.M., Schmidt, M., Brack, W., Krauss, M., (2015):
    Detecting a wide range of environmental contaminants in human blood samples—combining QuEChERS with LC-MS and GC-MS methods
    Anal. Bioanal. Chem. 407 (23), 7047 - 7054
    Volltext (URL)
  • Reischer, G.H., Kirschner, A., Schnitzer, G., Savio, D., Mach, R.L., Bahlmann, A., Schulze, T., Brack, W., Farnleitner, A.H., (2015):
    Microbial faecal source tracking
    In: Liška, I., Wagner, F., Sengl, M., Deutsch, K., Slobodník, J., (eds.)
    Joint Danube Survey 3 : a comprehensive analysis of Danube water quality
    International Commission for the Protection of the Danube River (ICPDR), Wien, p. 162 - 168
  • Rotter, S., Gunold, R., Mothes, S., Paschke, A., Brack, W., Altenburger, R., Schmitt-Jansen, M., (2015):
    Pollution-induced community tolerance to diagnose hazardous chemicals in multiple contaminated aquatic systems
    Environ. Sci. Technol. 49 (16), 10048 - 10056
    Volltext (URL)
  • Schulte, L.M., Krauss, M., Lötters, S., Schulze, T., Brack, W., (2015):
    Decoding and discrimination of chemical cues and signals: Avoidance of predation and competition during parental care behavior in sympatric poison frogs
    PLOS One 10 (7), e0129929
    Volltext (URL)
  • Schulze, T., Krauss, M., Novak, J., Hilscherova, K., Ait-Aissa, S., Creusot, N., Macova, M., Neale, P., Escher, B.I., Gomes, T., Tollefsen, K.E., Tarcai, Z., Shao, Y., Deutschmann, B., Seiler, T.-B., Hollert, H., Tarabek, P., Tousova, Z., Slobodnik, J., Walz, K.-H., Brack, W., (2015):
    Large volume sampling and effect-based screening
    In: Liška, I., Wagner, F., Sengl, M., Deutsch, K., Slobodník, J., (eds.)
    Joint Danube Survey 3 : a comprehensive analysis of Danube water quality
    International Commission for the Protection of the Danube River (ICPDR), Wien, p. 284 - 295
  • Wernersson, A.-S., Carere, M., Maggi, C., Tusil, P., Soldan, P., James, A., Sanchez, W., Dulio, V., Broeg, K., Reifferscheid, G., Buchinger, S., Maas, H., Van Der Grinten, E., O’Toole, S., Ausili, A., Manfra, L., Marziali, L., Polesello, S., Lacchetti, I., Mancini, L., Lilja, K., Linderoth, M., Lundeberg, T., Fjällborg, B., Porsbring, T., Larsson, D.G.J., Bengtsson-Palme, J., Förlin, L., Kienle, C., Kunz, P., Vermeirssen, E., Werner, I., Robinson, C.D., Lyons, B., Katsiadaki, I., Whalley, C., den Haan, K., Messiaen, M., Clayton, H., Lettieri, T., Negrão Carvalho, R., Gawlik, B.M., Hollert, H., Di Paolo, C., Brack, W., Kammann, U., Kase, R., (2015):
    The European technical report on aquatic effect-based monitoring tools under the water framework directive
    Environmental Sciences Europe 27 , art. 7
    Volltext (URL)
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2014 (11)

  • Bahlmann, A., Brack, W., Schneider, R.J., Krauss, M., (2014):
    Carbamazepine and its metabolites in wastewater: Analytical pitfalls and occurrence in Germany and Portugal
    Water Res. 57 , 104 - 114
    Volltext (URL)
  • Brils, J., Barcelo, D., Blum, W., Brack, W., Harris, B., Müller-Grabherr, D., Négrel, P., Ragnarsdottir, V., Salomons, W., Slob, A., Track, T., Vegter, J., Vermaat, J.E., (2014):
    Introduction: The need for risk-informed river basin management
    In: Brils, J., Brack, W., Müller-Grabherr, D., Négrel, P., Vermaat, J.E., (eds.)
    Risk-informed management of European river basins
    Handbook of Environmental Chemistry Series 29
    Springer, Berlin, Heidelberg, p. 1 - 18
  • Brils, J., Brack, W., Müller-Grabherr, D., Négrel, P., Vermaat, J.E., (eds., 2014):
    Risk-informed management of European river basins
    Handbook of Environmental Chemistry Series 29
    Springer, Berlin, Heidelberg, 395 pp.
  • Brils, J., Harris, B., Barceló, D., Blum, W., Brack, W., Müller-Grabherr, D., Négrel, P., Ragnarsdottir, V., Salomons, W., Slob, A., Track, T., Vegter, J., Vermaat, J.E., (2014):
    Synthesis and recommendations towards risk-informed river basin management
    In: Brils, J., Brack, W., Müller-Grabherr, D., Négrel, P., Vermaat, J.E., (eds.)
    Risk-informed management of European river basins
    Handbook of Environmental Chemistry Series 29
    Springer, Berlin, Heidelberg, p. 367 - 390
  • Brinkmann, M., Maletz, S., Krauss, M., Bluhm, K., Schiwy, S., Kuckelkorn, J., Tiehm, A., Brack, W., Hollert, H., (2014):
    Heterocyclic aromatic hydrocarbons show estrogenic activity upon metabolization in a recombinant transactivation assay
    Environ. Sci. Technol. 48 (10), 5892 - 5901
    Volltext (URL)
  • Fetter, E., Krauss, M., Brion, F., Kah, O., Scholz, S., Brack, W., (2014):
    Effect-directed analysis for estrogenic compounds in a fluvial sediment sample using transgenic cyp19a1b-GFP zebrafish embryos
    Aquat. Toxicol. 154 , 221 - 229
    Volltext (URL)
  • Hug, C., Ulrich, N., Schulze, T., Brack, W., Krauss, M., (2014):
    Identification of novel micropollutants in wastewater by a combination of suspect and nontarget screening
    Environ. Pollut. 184 , 25 - 32
    Volltext (URL)
  • Malaj, E., von der Ohe, P.C., Grote, M., Kühne, R., Mondy, C.P., Usseglio-Polatera, P., Brack, W., Schäfer, R.B., (2014):
    Organic chemicals jeopardize the health of freshwater ecosystems on the continental scale
    Proc. Natl. Acad. Sci. U.S.A. 111 (26), 9549 - 9554
    Volltext (URL)
  • Ulrich, N., Mühlenberg, J., Schüürmann, G., Brack, W., (2014):
    Linear solvation energy relationships as classifier in non-target analysis – an approach for isocratic liquid chromatography
    J. Chromatogr. A 1324 , 96 - 103
    Volltext (URL)
  • von der Ohe, P.C., Apitz, S.E., Arbaciauskas, K., Beketov, M.A., Borchardt, D., de Zwart, D., Goedkoop, W., Hein, M., Hellsten, S., Hering, D., Kefford, B.J., Panov, V.E., Schäfer, R.B., Segner, H., van Gils, J., Vegter, J.J., Wetzel, M.A., Brack, W., (2014):
    Status and causal pathway assessments supporting river basin management
    In: Brils, J., Brack, W., Müller-Grabherr, D., Négrel, P., Vermaat, J.E., (eds.)
    Risk-informed management of European river basins
    Handbook of Environmental Chemistry Series 29
    Springer, Berlin, Heidelberg, p. 53 - 149
  • von der Ohe, P.C., de Zwart, D., Semenzin, E., Apitz, S.E., Gottardo, S., Harris, B., Hein, M., Marcomini, A., Posthuma, L., Schäfer, R.B., Segner, H., Brack, W., (2014):
    Monitoring programmes, multiple stress analysis and decision support for river basin management
    In: Brils, J., Brack, W., Müller-Grabherr, D., Négrel, P., Vermaat, J.E., (eds.)
    Risk-informed management of European river basins
    Handbook of Environmental Chemistry Series 29
    Springer, Berlin, Heidelberg, p. 151 - 182
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2013 (8)

  • Brack, W., (2013):
    Effect-directed analysis in ecotoxicology
    In: Férard, J.-F., Blaise, C., (eds.)
    Encyclopedia of Aquatic Ecotoxicology
    Springer, Dordrecht, p. 387 - 394
    Volltext (URL)
  • Brack, W., Govender, S., Schulze, T., Krauss, M., Hu, M., Muz, M., Hollender, J., Schirmer, K., Schollee, J., Hidasi, A., Slobodnik, J., Rabova, Z., Ait-Aissa, S., Sonavane, M., Carere, M., Lamoree, M., Leonards, P., Tufi, S., Ouyang, X., Schriks, M., Thomas, K., de Almeida, A.C., Froment, J., Hammers-Wirtz, M., Ahel, M., Koprivica, S., Hollert, H., Seiler, T.-B., Di Paolo, C., Tindall, A., Spirhanzlova, P., (2013):
    EDA-EMERGE: an FP7 initial training network to equip the next generation of young scientists with the skills to address the complexity of environmental contamination with emerging pollutants
    Environmental Sciences Europe 25 , art. 18
    Volltext (URL)
  • Burgess, R.M., Ho, K.T., Brack, W., Lamoree, M., (2013):
    Effects-directed analysis (EDA) and toxicity identification evaluation (TIE): Complementary but different approaches for diagnosing causes of environmental toxicity
    Environ. Toxicol. Chem. 32 (9), 1935 - 1945
    Volltext (URL)
  • Gallampois, C.M.J., Schymanski, E.L., Bataineh, M., Buchinger, S., Krauss, M., Reifferscheid, G., Brack, W., (2013):
    Integrated biological–chemical approach for the isolation and selection of polyaromatic mutagens in surface waters
    Anal. Bioanal. Chem. 405 (28), 9101 - 9112
    Volltext (URL)
  • Grummt, T., Kuckelkorn, J., Bahlmann, A., Baumstark-Khan, C., Brack, W., Braunbeck, T., Feles, S., Gartiser, S., Glatt, H., Heinze, R., Hellweg, C.E., Hollert, H., Junek, R., Knauer, M., Kneib-Kissinger, B., Kramer, M., Krauss, M., Küster, E., Maletz, S., Meinl, W., Noman, A., Prantl, E.-M., Rabbow, E., Redelstein, R., Rettberg, P., Schadenboeck, W., Schmidt, C., Schulze, T., Seiler, T.-B., Spitta, L., Stengel, D., Waldmann, P., Eckhardt, A., (2013):
    Tox-Box: securing drops of life - an enhanced health-related approach for risk assessment of drinking water in Germany. Tox-Box: die Tropfen des Lebens bewahren - gesundheitsbasierte Risikobewertung für Trinkwasser in Deutschland
    Environmental Sciences Europe 25 , art. 27
    Volltext (URL)
  • Kühne, R., Ebert, R.-U., von der Ohe, P.C., Ulrich, N., Brack, W., Schüürmann, G., (2013):
    Read-across prediction of the acute toxicity of organic compounds toward the water flea Daphnia magna
    Mol. Inf. 32 (1), 108 - 120
    Volltext (URL)
  • Nováková, K., Kohoutek, J., Adamovský, O., Brack, W., Krauss, M., Bláha, L., (2013):
    Novel metabolites in cyanobacterium Cylindrospermopsis raciborskii with potencies to inhibit gap junctional intercellular communication
    J. Hazard. Mater. 262 , 571 - 579
    Volltext (URL)
  • Ulrich, N., Schüürmann, G., Brack, W., (2013):
    Prediction of gas chromatographic retention indices as classifier in non-target analysis of environmental samples
    J. Chromatogr. A 1285 , 139 - 147
    Volltext (URL)
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2012 (11)

  • Brack, W., (2012):
    Emerging substances of toxicological concern in a world full of chemicals - the NORMAN way to find the needles in the haystack
    Norman Bulletin 2012/3
    NORMAN Network, p. 1 - 2
  • de Deckere, E., Brack, W., Van Ballaer, B., von der Ohe, P.C., (2012):
    Identifying key stressors in Danube, Elbe, Llobregat and Scheldt based on regular monitoring data
    River Systems 20 (1-2), 87 - 99
    Volltext (URL)
  • Higley, E., Grund, S., Jones, P.D., Schulze, T., Seiler, T.-B., Lübcke-von Varel, U., Brack, W., Wölz, J., Zielke, H., Giesy, J.P., Hollert, H., Hecker, M., (2012):
    Endocrine disrupting, mutagenic, and teratogenic effects of upper Danube River sediments using effect-directed analysis
    Environ. Toxicol. Chem. 31 (5), 1053 - 1062
    Volltext (URL)
  • Lübcke-von Varel, U., Bataineh, M., Löffler, I., Schulze, T., Flückiger-Isler, S., Neca, J., Machala, M., Brack, W., Lohrmann, S., (2012):
    Identification and quantitative confirmation of dinitropyrenes and 3-nitrobenzanthrone as major mutagens in contaminated sediments
    Environ. Int. 44 (September 2012), 31 - 39
    Volltext (URL)
  • Malaj, E., Grote, M., Schäfer, R.B., Brack, W., von der Ohe, P.C., (2012):
    Physiological sensitivity of freshwater macroinvertebrates to heavy metals
    Environ. Toxicol. Chem. 31 (8), 1754 - 1764
    Volltext (URL)
  • Schulze, T., Brack, W., Walz, K.-H., (2012):
    Verfahren und Vorrichtung zur Festphasenextraktion aus einer Flüssigkeit
    Europäisches Patentamt, München
  • Schulze, T., Magerl, R., Streck, G., Brack, W., (2012):
    Use of factorial design for the multivariate optimization of polypropylene membranes for the cleanup of environmental samples using the accelerated membrane-assisted cleanup approach
    J. Chromatogr. A 1225 , 26 - 36
    Volltext (URL)
  • Schulze, T., Schymanski, E., Stravs, M., Neumann, S., Krauss, M., Singer, H., Hug, C., Gallampois, C., Hollender, J., Slobodnik, J., Brack, W., (2012):
    NORMAN MassBank: Towards a community-driven, open-access accurate mass spectral database for the identification of emerging pollutants
    Norman Bulletin 2012/3
    NORMAN Network, p. 9 - 11
  • Schymanski, E.L., Gallampois, C.M.J., Krauss, M., Meringer, M., Neumann, S., Schulze, T., Wolf, S., Brack, W., (2012):
    Consensus structure elucidation combining GC/EI-MS, structure generation and calculated properties
    Anal. Chem. 84 (7), 3287 - 3295
    Volltext (URL)
  • Ulrich, N., Mühlenberg, J., Retzbach, H., Schüürmann, G., Brack, W., (2012):
    Linear solvation energy relationships as classifiers in non-target analysis – a gas chromatographic approach
    J. Chromatogr. A 1264 , 95 - 103
    Volltext (URL)
  • von der Ohe, P.C., Schmitt-Jansen, M., Slobodnik, J., Brack, W., (2012):
    Triclosan – the forgotten priority substance?
    Environ. Sci. Pollut. Res. 19 (2), 585 - 591
    Volltext (URL)
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2011 (18)

  • Bougeard, C., Gallampois, C., Brack, W., (2011):
    Passive dosing: an approach to control mutagen exposure in the Ames fluctuation test
    Chemosphere 83 (4), 409 - 414
    Volltext (URL)
  • Brack, W., (ed., 2011):
    Effect-directed analysis of complex environmental contamination
    Handbook of Environmental Chemistry Series 15
    Springer, Berlin, Heidelberg, 345 pp.
    Volltext (URL)
  • Brack, W., Burgess, R.M., (2011):
    Considerations for incorporating bioavailability in effect-directed analysis and toxicity identification evaluation
    In: Brack, W., (ed.)
    Effect-directed analysis of complex environmental contamination
    Handbook of Environmental Chemistry Series 15
    Springer, Berlin, Heidelberg, p. 41 - 68
    Volltext (URL)
  • Brack, W., (2011):
    Impact assessment of environmental key pollutants on aquatic ecosystems
    In: Quevauviller, P., Borchers, U., Thompson, C., Simonart, T., (eds.)
    The water framework directive: action programmes and adaptation to climate change
    Royal Society of Chemistry (RSC), Cambridge, p. 189 - 202
  • Brack, W., Ulrich, N., Bataineh, M., (2011):
    Separation techniques in effect-directed analysis
    In: Brack, W., (ed.)
    Effect-directed analysis of complex environmental contamination
    Handbook of Environmental Chemistry Series 15
    Springer, Berlin, Heidelberg, p. 83 - 118
    Volltext (URL)
  • Burgess, R.M., Ho, K.T., Biales, A.D., Brack, W., (2011):
    Recent developments in whole sediment toxicity identification evaluations: innovations in manipulations and endpoints
    In: Brack, W., (ed.)
    Effect-directed analysis of complex environmental contamination
    Handbook of Environmental Chemistry Series 15
    Springer, Berlin, Heidelberg, p. 19 - 40
    Volltext (URL)
  • dos Anjos, N.A., Schulze, T., Brack, W., Val, A.L., Schirmer, K., Scholz, S., (2011):
    Identification and evaluation of cyp1a transcript expression in fish as molecular biomarker for petroleum contamination in tropical fresh water ecosystems
    Aquat. Toxicol. 103 (1-2), 46 - 52
    Volltext (URL)
  • Grung, M., Naes, K., Fogelberg, O., Nilsen, A.J., Brack, W., Lübcke-von Varel, U., Thomas, K.V., (2011):
    Effects-directed analysis of sediments from polluted marine sites in Norway
    J. Toxicol. Env. Health Part A 74 (7 & 9), 439 - 454
    Volltext (URL)
  • Lübcke-von Varel, U., Machala, M., Ciganek, M., Neca, J., Pencikova, K., Palkova, L., Vondracek, J., Löffler, I., Streck, G., Reifferscheid, G., Flückiger-Isler, S., Weiss, J.M., Lamoree, M., Brack, W., (2011):
    Polar compounds dominate in vitro effects of sediment extracts
    Environ. Sci. Technol. 45 (6), 2384 - 2390
    Volltext (URL)
  • Schmitt, C., Streck, G., Lamoree, M., Leonards, P., Brack, W., de Deckere, E., (2011):
    Effect directed analysis of riverine sediments - the usefulness of Potamopyrgus antipodarum for in vivo effect confirmation of endocrine disruption
    Aquat. Toxicol. 101 (1), 237 - 243
    Volltext (URL)
  • Schymanski, E.L., Meringer, M., Brack, W., (2011):
    Automated strategies to identify compounds on the basis of GC/EI-MS and calculated properties
    Anal. Chem. 83 (3), 903 - 912
    Volltext (URL)
  • Schymanski, E., Schulze, T., Hermanns, J., Brack, W., (2011):
    Computer tools for structure elucidation in effect-directed analysis
    In: Brack, W., (ed.)
    Effect-directed analysis of complex environmental contamination
    Handbook of Environmental Chemistry Series 15
    Springer, Berlin, Heidelberg, p. 167 - 198
    Volltext (URL)
  • Tuikka, A., Schmitt, C., Höss, S., Bandow, N., von der Ohe, P.C., de Zwart, D., de Deckere, E., Streck, G., Mothes, S., van Hattum, B., Kocan, A., Brix, R., Brack, W., Barceló, D., Sormunen, A.J., Kukkonen, J.V.K., (2011):
    Toxicity assessment of sediments from three European river basins using a sediment contact test battery
    Ecotox. Environ. Safe. 74 (1), 123 - 131
    Volltext (URL)
  • Ulrich, N., Schüürmann, G., Brack, W., (2011):
    Linear solvation energy relationships as classifiers in non-target analysis - a capillary liquid chromatography approach
    J. Chromatogr. A 1218 (45), 8192 - 8196
    Volltext (URL)
  • von der Ohe, P.C., Dulio, V., Slobodnik, J., de Deckere, E., Kühne, R., Ebert, R.U., Ginebreda, A., De Cooman, W., Schüürmann, G., Brack, W., (2011):
    A new risk assessment approach for the prioritization of 500 classical and emerging organic microcontaminants as potential river basin specific pollutants under the European Water Framework Directive
    Sci. Total Environ. 409 (11), 2064 - 2077
    Volltext (URL)
  • Wölz, J., Grosshans, K., Streck, G., Schulze, T., Rastall, A., Erdinger, L., Brack, W., Fleig, M., Kühlers, D., Braunbeck, T., Hollert, H., (2011):
    Estrogen receptor mediated activity in bankside groundwater, with flood suspended particulate matter and floodplain soil – an approach combining tracer substance, bioassay and target analysis
    Chemosphere 85 (5), 717 - 723
    Volltext (URL)
  • Wölz, J., Schulze, T., Lübcke-von Varel, U., Fleig, M., Reifferscheid, G., Brack, W., Kühlers, D., Braunbeck, T., Hollert, H., (2011):
    Investigation on soil contamination at recently inundated and non-inundated sites
    J. Soils Sediments 11 (1), 82 - 92
    Volltext (URL)
  • Zielke, H., Seiler, T.-B., Niebergall, S., Leist, E., Brinkmann, M., Spira, D., Streck, G., Brack, W., Feiler, U., Braunbeck, T., Hollert, H., (2011):
    The impact of extraction methodologies on the toxicity of sediments in the zebrafish (Danio rerio) embryo test
    J. Soils Sediments 11 (2), 352 - 363
    Volltext (URL)
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2010 (12)

  • Altenburger, R., Berns, A.E., Bittens, M., Brack, W., Burauel, P., Centler, F., Daus, B., Goss, K.-U., Harms, H., Kopinke, F.-D., Kühnel, D., Liess, M., Mackenzie, K., Miltner, A., Thullner, M., Wennrich, R., Wick, L.Y., (2010):
    Chemicals in the environment (CITE). Report of the First Annual Conference of the Helmholtz research topic CITE
    UWSF 22 (4), 502 - 506
    Volltext (URL)
  • Bandow, N., Altenburger, R., Brack, W., (2010):
    Application of nd-SPME to determine freely dissolved concentrations in the presence of green algae and algae-water partition coefficients
    Chemosphere 79 (11), 1070 - 1076
    Volltext (URL)
  • Bataineh, M., Lübcke-von Varel, U., Hayen, H., Brack, W., (2010):
    HPLC/APCI-FTICR-MS as a tool for identification of partial polar mutagenic compounds in effect-directed analysis
    J. Am. Soc. Mass Spectrom. 21 (6), 1016 - 1027
    Volltext (URL)
  • Brack, W., Bakker, J.F., de Deckere, E., de Zwart, D., Hamers, T., Hein, M., Leonards, P., Lübcke-von Varel, U., Schmitt, C., Schmitt-Jansen, M., von der Ohe, P.C., (2010):
    MODELKEY. European rivers under toxic stress
    In: Settele, J., Penev, L., Georgiev, T., Grabaum, R., Grobelnik, V., Hammen, V., Klotz, S., Kotarac, M., Kühn, I., (eds.)
    Atlas of biodiversity risk
    Pensoft, Sofia, p. 116 - 118
    Volltext (URL)
  • Brills, J., Quevauviller, P., Slob, A., Blind, M., Davy, T., Carere, M., Amorsi, N., Brack, W., Borchers, U., Thompson, C., Villessot, D., (2010):
    The European Water Framework Directive beyond 2010: let actions speak louder than words
    J. Environ. Monit. 12 (12), 2204 - 2206
    Volltext (URL)
  • Hein, M., Rotter, S., Schmitt-Jansen, M., von der Ohe, P.C., Brack, W., de Deckere, E., Schmitt, C., de Zwart, D., Posthuma, L., Foekema, E.M., Muñoz, I., Sabater, S., Segner, H., Semenzin, E., Markomini, A., van Gils, J., van Hattum, B., van Vliet, L.A., (2010):
    MODELKEY. Key findings and recommendations for reaching the EU Water Framework Directive's quality objectives
    UWSF 22 (3), 217 - 228
    Volltext (URL)
  • Meinert, C., Brack, W., (2010):
    Optimisation of trapping parameters in preparative capillary gas chromatography for the application in effect-directed analysis
    Chemosphere 78 (3), 416 - 422
    Volltext (URL)
  • Meinert, C., Schymanski, E., Küster, E., Kühne, R., Schüürmann, G., Brack, W., (2010):
    Application of preparative capillary gas chromatography (pcGC), automated structure generation and mutagenicity prediction to improve effect-directed analysis of genotoxicants in a contaminated groundwater
    Environ. Sci. Pollut. Res. 17 (4), 885 - 897
    Volltext (URL)
  • Schmitt, C., Balaam, J., Leonards, P., Brix, R., Streck, G., Tuikka, A., Bervoets, L., Brack, W., van Hattum, B., Meire, P., de Deckere, E., (2010):
    Characterizing field sediments from three European river basins with special emphasis on endocrine effects - A recommendation for Potamopyrgus antipodarum as test organism
    Chemosphere 80 (1), 13 - 19
    Volltext (URL)
  • Schulze, T., Weiss, S., Schymanski, E., von der Ohe, P.C., Schmitt-Jansen, M., Altenburger, R., Streck, G., Brack, W., (2010):
    Identification of a phytotoxic photo-transformation product of diclofenac using effect-directed analysis
    Environ. Pollut. 158 (5), 1461 - 1466
    Volltext (URL)
  • Wölz, J., Brack, W., Moehlenkamp, C., Claus, E., Braunbeck, T., Hollert, H., (2010):
    Effect-directed analysis of Ah receptor-mediated activities caused by PAHs in suspended particulate matter sampled in flood events
    Sci. Total Environ. 408 (16), 3327 - 3333
    Volltext (URL)
  • Wölz, J., Fleig, M., Schulze, T., Maletz, S., Lübcke-von Varel, U., Reifferscheid, G., Kühlers, D., Braunbeck, T., Brack, W., Hollert, H., (2010):
    Impact of contaminants bound to suspended particulate matter in the context of flood events
    J. Soils Sediments 10 (6), 1174 - 1185
    Volltext (URL)
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2009 (14)

  • Bandow, N., Altenburger, R., Lübcke-von Varel, U., Paschke, A., Streck, G., Brack, W., (2009):
    Partitioning-based dosing: an approach to include bioavailability in the effect-directed analysis of contaminated sediment samples
    Environ. Sci. Technol. 43 (10), 3891 - 3896
    Volltext (URL)
  • Bandow, N., Altenburger, R., Streck, G., Brack, W., (2009):
    Effect-directed analysis of contaminated sediments with partition-based dosing using green algae cell multiplication inhibition
    Environ. Sci. Technol. 43 (19), 7343 - 7349
    Volltext (URL)
  • Brack, W., Apitz, S.E., Borchardt, D., Brils, J., Cardoso, A.C., Foekema, E.M., van Gils, J., Jansen, S., Harris, B., Hein, M., Heise, S., Hellsten, S., de Maagd, P.G.-J., Müller, D., Panov, V.E., Posthuma, L., Quevauviller, P., Verdonschot, P.F.M., von der Ohe, P.C., (2009):
    Towards a holistic and risk-based management of European river basins
    Integr. Environ. Assess. Manag. 5 (1), 5 - 10
    Volltext (URL)
  • Brack, W., Bandow, N., Schwab, K., Schulze, T., Streck, G., (2009):
    Bioavailability in effect-directed analysis of organic toxicants in sediments
    Trac-Trends Anal. Chem. 28 (5), 543 - 549
    Volltext (URL)
  • Brack, W., Bandow, N., Schwab, K., Schulze, T., Streck, G., (2009):
    Identifizierung toxischer Verbindungen in Sedimenten: Ansätze zur Integration von Wirkung und Bioverfügbarkeit
    UWSF 21 (3), 240 - 244
    Volltext (URL)
  • Brack, W., Posthuma, L., Hein, M., von der Ohe, P.C., (2009):
    European river basins at risk
    Integr. Environ. Assess. Manag. 5 (1), 2 - 4
    Volltext (URL)
  • Gaspare, L., Machiwa, J.F., Mdachi, S.J.M., Streck, G., Brack, W., (2009):
    Polycyclic aromatic hydrocarbon (PAH) contamination of surface sediments and oysters from the inter-tidal areas of Dar es Salaam, Tanzania
    Environ. Pollut. 157 (1), 24 - 34
    Volltext (URL)
  • Hollert, H., Claus, E., Ahlf, W., Brack, W., Braunbeck, T., Hudjetz, S., Manz, W., Ratte, H.T., Reifferscheid, G., Schäffer, A., Schulze, T., Schwarzbauer, J., Heininger, P., (2009):
    Über die Notwendigkeit der wirkungsorientierten Analytik in einer umfassenden Wasserforschung
    UWSF 21 (3), 235 - 237
    Volltext (URL)
  • Kaisarevic, S., Lübcke-von Varel, U., Orcic, D., Streck, G., Schulze, T., Pogrmic, K., Teodorovic, I., Brack, W., Kovacevic, R., (2009):
    Effect-directed analysis of contaminated sediment from the wastewater canal in Pancevo industrial area, Serbia
    Chemosphere 77 (7), 907 - 913
    Volltext (URL)
  • Schwab, K., Altenburger, R., Lübcke-von Varel, U., Streck, G., Brack, W., (2009):
    Effect-directed analysis of sediment-associated algal toxicants at selected hot spots in the river Elbe basin with a special focus on bioaccessibility
    Environ. Toxicol. Chem. 28 (7), 1506 - 1517
    Volltext (URL)
  • Schymanski, E., Bataineh, M., Goss, K.U., Brack, W., (2009):
    Integrated analytical and computer tools for structure elucidation in effect-directed analysis
    Trac-Trends Anal. Chem. 28 (5), 550 - 561
    Volltext (URL)
  • Schymanski, E., Meringer, M., Brack, W., (2009):
    Matching structures to mass spectra using fragmentation patterns: are the results as good as they look?
    Anal. Chem. 81 (9), 3608 - 3617
    Volltext (URL)
  • von der Ohe, P.C., de Deckere, E., Prüß, A., Muñoz, I., Wolfram, G., Villagrasa, M., Ginebreda, A., Hein, M., Brack, W., (2009):
    Toward an integrated assessment of the ecological and chemical status of European river basins
    Integr. Environ. Assess. Manag. 5 (1), 50 - 61
    Volltext (URL)
  • Vykopalova, L., Pencikova, K., Ciganek, M., Neca, J., Vondracek, J., Brack, W., Luebcke-Von Varel, U., Streck, G., Machala, M., (2009):
    Identification and toxicological evaluation of musk fragrances and thiophenes in extracts of river sediment samples
    Toxicol. Lett. 189 (Suppl. 1), S198 - S199
    Volltext (URL)
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2008 (8)

  • Brack, W., Bláha, L., Giesy, J.P., Grote, M., Möder, M., Schrader, S., Hecker, M., (2008):
    Polychlorinated naphthalenes and other dioxin-like acting compounds in Elbe river sediments
    Environ. Toxicol. Chem. 27 (3), 519 - 528
    Volltext (URL)
  • Brack, W., Schmitt-Jansen, M., Machala, M., Brix, R., Barceló, D., Schymanski, E., Streck, G., Schulze, T., (2008):
    How to confirm identified toxicants in effect-directed analysis
    Anal. Bioanal. Chem. 390 (8), 1959 - 1973
    Volltext (URL)
  • Lübcke-von Varel, U., Streck, G., Brack, W., (2008):
    Automated fractionation procedure for polycyclic aromatic compounds in sediment extracts on three coupled normal-phase high-performance liquid chromatography columns
    J. Chromatogr. A 1185 (1), 31 - 42
    Volltext (URL)
  • Mages, M., Bandow, N., Küster, E., Brack, W., von Tümpling, W., (2008):
    Zinc and cadmium accumulation in single zebrafish (Danio rerio) embryos - A total reflection X-ray fluorescence spectrometry application
    Spectroc. Acta Pt. B-Atom. Spectr. 63 (12), 1443 - 1449
    Volltext (URL)
  • Schäfer, R.B., Mueller, R., Brack, W., Wenzel, K.-D., Streck, G., Ruck, W., Liess, M., (2008):
    Determination of 10 particle-associated multiclass polar and semi-polar pesticides from small streams using accelerated solvent extraction
    Chemosphere 70 (11), 1952 - 1960
    Volltext (URL)
  • Schymanski, E., Meinert, C., Meringer, M., Brack, W., (2008):
    The use of MS classifiers and structure generation to assist in the identification of unknowns in effect-directed analysis
    Anal. Chim. Acta 615 (2), 136 - 147
    Volltext (URL)
  • Streck, G., Schulze, T., Brack, W., (2008):
    Accelerated membrane-assisted clean-up as a tool for the clean-up of extracts from biological tissues
    J. Chromatogr. A 1196-1197 , 33 - 40
    Volltext (URL)
  • Streck, G., Schulze, T., Brack, W., (2008):
    Accelerated Membrane Assisted Clean-up: Eine leistungsfähige Methode zur Aufreinigung matrixbehafteter Extrakte
    LC-GC Ads März/April 2008 , 6 - 10
zum Inhalt

2007 (5)

  • Bakker, J.F., Belzunce-Segarra, M.J., Castro, R., van de Heuvel-Greve, M., Klamer, H.J.C., Brack, W., Altenburger, R., Poulsen, V., Thomas, K.V., Leonards, P.E.G., (2007):
    Effect directed analysis and toxicity identification evaluation
    In: Barceló, D., Petrovic, M., (eds.)
    Sediment quality and impact assessment of pollutants
    Sustainable Management of Sediment Resources Vol. 1
    Elsevier, Amsterdam, p. 163 - 214
  • Brack, W., Klamer, H.J.C., López de Alda, M., Barceló, D., (2007):
    Effect-directed analysis of key toxicants in European river basins - a review
    Environ. Sci. Pollut. Res. 14 (1), 30 - 38
    Volltext (URL)
  • Meinert, C., Moeder, M., Brack, W., (2007):
    Fractionation of technical p-nonylphenol with preparative capillary gas chromatography
    Chemosphere 70 (2), 215 - 223
    Volltext (URL)
  • Schwab, K., Brack, W., (2007):
    Large volume TENAX® extraction of the bioaccessible fraction of sediment-associated organic compounds for a subsequent effect-directed analysis
    J. Soils Sediments 7 (3), 178 - 186
    Volltext (URL)
  • von der Ohe, P.C., Prüß, A., Schäfer, R.B., Liess, M., de Deckere, E., Brack, W., (2007):
    Water quality indices across Europe - a comparison of the good ecological status of five river basins
    J. Environ. Monit. 9 (9), 970 - 978
    Volltext (URL)
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2006 (5)

  • Altenburger, R., Brack, W., Greco, W.R., Grote, M., Jung, K., Ovari, A., Riedl, J., Schwab, K., Küster, E., (2006):
    On the mode of action of N-phenyl-2-naphthylamine in plants
    Environ. Sci. Technol. 40 (19), 6163 - 6169
    Volltext (URL)
  • Böhmler, G., Brack, W., Gareis, M., Goehrlich, R., (2006):
    Von der Wirkung zur Substanz: Wirkungsbezogene Analytik als neue Untersuchungsstrategie in der Lebensmittelkontrolle
    J. Verbr. Lebensm. 1 (4), 294 - 300
    Volltext (URL)
  • Brack, W., (2006):
    Wirkungsorientierte Analytik komplexer Mischungen. Erfahrungen aus der Umwelt- und Ökotoxikologie für die Lebensmitteluntersuchung
    J. Verbr. Lebensm. 1 (4), 301 - 309
    Volltext (URL)
  • Brack, W., (2006):
    MODELKEY: Entschlüsselung von Ursache-Wirkungs-Beziehungen für ein besseres Flussgebietsmanagement
    Forum der Geoökologie 17 (1), 37 - 39
  • Brack, W., (2006):
    MODELKEY: towards a better impact and cause analysis
    SETAC Globe 7 (2), 13
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2005 (9)

  • Brack, W., Bakker, J., de Deckere, E., Deerenberg, C., van Gils, J., Hein, M., Jurajda, P., Kooijman, B., Lamoree, M., Lek, S., López de Alda, M.J., Marcomini, A., Muñoz, I., Rattei, S., Segner, H., Thomas, K., von der Ohe, P.C., Westrich, B., de Zwart, D., Schmitt-Jansen, M., (2005):
    MODELKEY. Models for assessing and forecasting the impact of environmental key pollutants on freshwater and marine ecosystems and biodiversity
    Environ. Sci. Pollut. Res. 12 (5), 252 - 256
    Volltext (URL)
  • Brack, W., Schirmer, K., Erdinger, L., Hollert, H., (2005):
    Effect-directed analysis of mutagens and ethoxyresorufin-O-deethylase inducers in aquatic sediments
    Environ. Toxicol. Chem. 24 (10), 2445 - 2458
    Volltext (URL)
  • Grote, M., Altenburger, R., Brack, W., Moschütz, S., Mothes, S., Michael, C., Narten, G.-B., Paschke, A., Schirmer, K., Walter, H.A., Wennrich, R., Wenzel, K.-D., Schüürmann, G., (2005):
    Ecotoxicological profiling of transect river Elbe sediments
    Acta Hydrochim. Hydrobiol. 33 (5), 555 - 569
    Volltext (URL)
  • Grote, M., Brack, W., Altenburger, R., (2005):
    Identification of toxicants from marine sediment using effect-directed analysis
    Environ.Toxicol. 20 (5), 475 - 486
    Volltext (URL)
  • Grote, M., Brack, W., Walter, H.A., Altenburger, R., (2005):
    Light as a confounding factor for toxicity assessment of complex contaminated sediments
    Environ. Toxicol. Chem. 24 (12), 3143 - 3152
    Volltext (URL)
  • Grote, M., Brack, W., Walter, H.A., Altenburger, R., (2005):
    Confirmation of cause-effect relationships using effect-directed analysis for complex environmental samples
    Environ. Toxicol. Chem. 24 (6), 1420 - 1427
    Volltext (URL)
  • Hollert, H., Dürr, M., Holtey-Weber, R., Islinger, M., Brack, W., Färber, H., Erdinger, L., Braunbeck, T., (2005):
    Endocrine disruption of water and sediment extracts in a non-radioactive dot blot/RNAse protection-assay using isolated hepatocytes of rainbow trout. Deficiencies between bioanalytical effectiveness and chemically determined concentrations and how to explain them
    Environ. Sci. Pollut. Res. 12 (6), 347 - 360
    Volltext (URL)
  • Olajire, A.A., Altenburger, R., Küster, E., Brack, W., (2005):
    Chemical and ecotoxicological assessment of polycyclic aromatic hydrocarbon-contaminated sediments of the Niger Delta, Southern Nigeria
    Sci. Total Environ. 340 (1-3), 123 - 136
    Volltext (URL)
  • Olajire, A.A., Brack, W., (2005):
    Polycyclic aromatic hydrocarbons in Niger Delta soil: contamination sources and profiles
    Int. J. Environ. Sci. Technol. 2 (4), 343 - 352
    Volltext (URL)
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2004 (2)

  • Grote, M., Altenburger, R., Brack, W., Möckel, C., Moschütz, S., Mothes, S., Michael, C., Narten, G.-B., Paschke, A., Schirmer, K., Walter, H., Wennrich, R., Wenzel, K.-D., Schüürmann, G., (2004):
    Identifizierung und Analyse des ökotoxischen Potentials von Flusssedimenten als Folge der durch Hochwasser mobilisierten Kontamination
    In: Geller, W., Ockenfeld, K., Böhme, M., Knöchel, A., (Hrsg.)
    Schadstoffbelastung nach dem Elbe-Hochwasser 2002. Endbericht des Ad-hoc-Verbundprojekts
    UFZ Leipzig-Halle GmbH, Magdeburg, S. 314 - 329
  • Vondracek, J., Chramostová, K., Plísková, M., Bláha, L., Brack, W., Kozubík, A., Machala, M., (2004):
    Induction of aryl hydrocarbon receptor-mediated and estrogen receptor-mediated activities, and modulation of cell proliferation by dinaphthofurans
    Environ. Toxicol. Chem. 23 (9), 2214 - 2220
    Volltext (URL)
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2003 (7)

  • Altenburger, R., Brack, W., Grote, M., Moschütz, S., Paschke, A., Schirmer, K., Walter, H., Wenzel, K., Schüürmann, G., (2003):
    Identifizierung und Analyse des ökotoxikologischen Potentials von Flußsedimenten als Folge der durch Hochwasser mobilisierten Kontaminationen
    Schadstoffbelastung im Mulde- und Elbe-Einzugsgebiet nach dem Augusthochwasser 2002,
    Ergebnisse und Forschungsbedarf, Tagungsband. Statusseminar des BMBF-Ad-hoc-Verbundprojektes, Freiberg, 27.-29. August 2003

    UFZ Leipzig-Halle GmbH, Magdeburg, p. 9 - 12
  • Brack, W., (2003):
    Effect-directed analysis: a promising tool for the identification of organic toxicants in complex mixtures?
    Anal. Bioanal. Chem. 377 (3), 397 - 407
    Volltext (URL)
  • Brack, W., Altenburger, R., Küster, E., Meissner, B., Wenzel, K.-D., Schüürmann, G., (2003):
    Identification of toxic products of anthracene photomodification in simulated sunlight
    Environ. Toxicol. Chem. 22 (10), 2228 - 2237
    Volltext (URL)
  • Brack, W., Kind, T., Hollert, H., Schrader, S., Möder, M., (2003):
    Sequential fractionation procedure for the identification of potentially cytochrome P4501A-inducing compounds
    J. Chromatogr. A 986 (1), 55 - 66
    Volltext (URL)
  • Brack, W., Kind, T., Hollert, H., Schrader, S., Möder, M., (2003):
    Erratum to "Sequential fractionation procedure for the identification of potentially cytochrome P4501A-inducing compounds" (vol 986, pg 55, 2003)
    J. Chromatogr. A 993 (1-2), 223 - 223
    Volltext (URL)
  • Brack, W., Kind, T., Schrader, S., Möder, M., Schüürmann, G., (2003):
    Polychlorinated naphthalenes in sediments from the industrial region of Bitterfeld
    Environ. Pollut. 121 (1), 81 - 85
    Volltext (URL)
  • Brack, W., Schirmer, K., (2003):
    Effect-directed identification of oxygen and sulfur heterocycles as major polycyclic aromatic cytochrome P4501A-inducers in a contaminated sediment
    Environ. Sci. Technol. 37 (14), 3062 - 3070
    Volltext (URL)
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2002 (4)

  • Brack, W., Altenburger, R., (2002):
    Effektorientierte Identifikation toxischer Verbindungen
    Mitteilungen der Fachgruppe Umweltchemie und Ökotoxikologie / Gesellschaft Deutscher Chemiker 8 , 6 - 8
  • Brack, W., Altenburger, R., Dorusch, F., Hubert, A., Möder, M., Morgenstern, P., Moschütz, S., Mothes, S., Schirmer, K., Wennrich, R., Wenzel, K.-D., Schüürmann, G., (2002):
    Hochwasser 2002 - Chemische und toxische Belastung überschwemmter Gemeinden im Raum Bitterfeld
    UWSF 14 (4), 213 - 220
    Volltext (URL)
  • Brack, W., Schirmer, K., Kind, T., Schrader, S., Schüürmann, G., (2002):
    Effect-directed fractionation and identification of cytochrome P4501A-inducing halogenated aromatic hydrocarbons in a contaminated sediment
    Environ. Toxicol. Chem. 21 (12), 2654 - 2662
    Volltext (URL)
  • Hollert, H., Dürr, M., Olsmann, H., Halldin, K., van Bavel, B., Brack, W., Tysklind, M., Engwall, M., Braunbeck, T., (2002):
    Biological and chemical determination of dioxin-like compounds in sediments by means of a sediment triad approach in the catchment area of the river Neckar
    Ecotoxicology 11 (5), 323 - 336
    Volltext (URL)
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2000 (6)

  • Brack, W., Altenburger, R., (2000):
    Identifikation giftiger Inhaltsstoffe - ein wichtiger Schritt zur Gefährdungsabschätzung und Sanierung
    UFZ-Jahresbericht '98-'99
    UFZ Leipzig-Halle GmbH, Leipzig, S. 26 - 34
    Volltext (PDF)
  • Brack, W., Altenburger, R., Ensenbach, U., Nehls, S., Segner, H., (2000):
    Biotestorientierte Identifikation toxischer organischer Sedimentinhaltstoffe - Ein Beitrag zur Risikoanalyse komplexer Kontaminationen am Beispiel des Spittelwassers. Mitteilung Nr. 22. Sedimentbewertung in europäischen Flußgebieten. Beiträge zum internationalen Symposium vom 12.-14. April 1999
    "Sedimentbewertung in europäischen Flußgebieten", Koblenz, 12.-14.4.1999
    Bundesanstalt für Gewässerkunde, Koblenz, p. 135 - 141
  • Brack, W., Altenburger, R., Ensenbach, U., Nehls, S., Segner, H., Schüürmann, G., (2000):
    Wirkungsorientierte Identifikation toxischer organischer Inhaltsstoffe in Flußsedimenten
    In: Friese, K., Witter, B., Miehlich, G., Rode, M., (Hrsg.)
    Stoffhaushalt von Auenökosystemen. Böden und Hydrologie, Schadstoffe, Bewertungen
    Springer, Berlin, Heidelberg, New York, S. 337 - 346
    Volltext (URL)
  • Brack, W., Paschke, A., Segner, H., Schüürmann, G., Wennrich, R., (2000):
    Urease inhibition: a tool for toxicity identification in sediment elutriates
    Chemosphere 40 (8), 829 - 834
    Volltext (URL)
  • Brack, W., Segner, H., Möder, M., Schüürmann, G., (2000):
    Fixed-effect level toxicity equivalents - A suitable parameter for assessing ethoxyresorufin-o-dethylase induction potency in complex environmental samples
    Environ. Toxicol. Chem. 19 (10), 2493 - 2501
    Volltext (URL)
  • Friese, K., Witter, B., Brack, W., Büttner, O., Krüger, F., Kunert, M., Rupp, H., Miehlich, G., Gröngröft, G., Schwartz, R., van der Veen, A., Zachmann, D.R., (2000):
    Distribution and fate of organic and inorganic contaminants in a river floodplain - results of a case study on the River Elbe, Germany
    In: Wise, D.L., Trantolo, D., Cichon, E.J., Inyang, H.I., Stottmeister, U., (eds.)
    Remediation engineering of contaminated soils
    Environmental Science and Pollution Control 23
    Marcel Dekker, New York, p. 373 - 426
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1999 (3)

  • Brack, W., Altenburger, R., Ensenbach, U., Möder, M., Segner, H., Schüürmann, G., (1999):
    Bioassay-directed identification of organic toxicants in river sediment in the industrial region of Bitterfeld (Germany) - a contribution to hazard assessment
    Arch. Environ. Contam. Toxicol 37 (2), 164 - 174
    Volltext (URL)
  • Brack, W., (1999):
    Sequentielle Teststrategie zur Identifikation toxischer organischer Substanzen in Porengewässern und Sedimentextraten. DVWK-Methodenstudie
    In: Kern, U., Westrich, B., (Hrsg.)
    Methoden zur Erkundung, Untersuchung und Bewertung von Sedimentablagerungen und Schwebstoffen in Gewässern
    DVWK-Schriften Band 128
    Wirtschafts- und Verlagsgesellschaft Gas und Wasser, Bonn, S. 282 - 289
  • Friese, K., Krüger, F., Brack, W., Lohse, M., Miehlich, G., Schwartz, R., Witter, B., Khalamtzeva, P., Yashin, V., (1999):
    Hochwassergebundener Schadstoffeintrag in Auen der Elbe und der Oka: Aktueller Stand des russisch-deutschen Kooperationsprojektes
    Russisch-Deutsches Seminar "Ökomonitoring großer Gewässer und Umwelttechnologien zur Vermeidung von Schadstoffeinträgen", 9./10.2.1999, Haus der Wissenschaft und Kultur der Russischen Förderation, Berlin
    p. 27 - 30
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1998 (6)

  • Brack, W., Altenburger, R., Ensenbach, U., Nehls, S., Segner, H., Schüürmann, G., (1998):
    Identifikation ökotoxikologisch wirksamer Substanzen in Sedimenten des Spittelwassers
    In: Geller, W., Punčochář, P., Bornhöft, D., Bouček, J., Feldmann, H., Guhr, H., Mohaupt, V., Simon, M., Smrtˇák, J., Spoustová, J., Uhlmann, O., (Hrsg.)
    Gewässerschutz im Einzugsgebiet der Elbe. 8. Magdeburger Gewässerschutzseminar, Oktober 1998, Karlsbad (Tschechien)
    B.G. Teubner, Stuttgart, Leipzig, S. 149 - 150
    Volltext (URL)
  • Brack, W., Frank, H., (1998):
    Chlorophyll a fluorescence: A tool for the investigation of toxic effects in the photosynthetic apparatus
    Ecotox. Environ. Safe. 40 (1-2), 34 - 41
    Volltext (URL)
  • Brack, W., Rottler, H., Frank, H., (1998):
    Volatile fractions of landfill leachates and their effect on Chlamydomonas reinhardtii: In vivo chlorophyll a fluorescence
    Environ. Toxicol. Chem. 17 (10), 1982 - 1991
    Volltext (URL)
  • Ensenbach, U., Altenburger, R., Behrens, A., Brack, W., Knops, M., Navas, J.M., Nehls, S., Schrag, B., Segner, H., Sturm, A., Walter, H., Schüürmann, G., (1998):
    Ökotoxikologische Analyse komplexer Stoffgemische
    Tagungsbericht 1997 der Deutschen Gesellschaft für Limnologie (DGL) und der deutschen und österreichischen Sektion der Societas Internationalis Limnologiae (SIL). Band II, Frankfurt am Main, 22. - 26.9.1997
    Deutsche Gesellschaft für Limnologie, Krefeld, p. 882 - 885
  • Ensenbach, U., Altenburger, R., Brack, W., Paschke, A., Popp, P., Segner, H., Wennrich, R., Schüürmann, G., (1998):
    Ökotoxikologische Charakterisierung von Sedimenten der Saale
    In: Geller, W., Punčochář, P., Bornhöft, D., Bouček, J., Feldmann, H., Guhr, H., Mohaupt, V., Simon, M., Smrtˇák, J., Spoustová, J., Uhlmann, O., (Hrsg.)
    Gewässerschutz im Einzugsgebiet der Elbe. 8. Magdeburger Gewässerschutzseminar, Oktober 1998, Karlsbad (Tschechien)
    B.G. Teubner, Stuttgart, Leipzig, S. 151 - 152
    Volltext (URL)
  • Friese, K., Brack, W., Krüger, F., Lohse, M., Miehlich, G., Rupp, H., Schwartz, R., Witter, B., Khalamtzeva, I., Pylenok, P., Sergueev, S., Iashin, V., (1998):
    Hochwassergebundener Schadstoffeintrag in Auen der Elbe und der Oka: Aktueller Stand eines BMBF- und UFZ-geförderten russisch-deutschen Kooperationsprojektes
    In: Geller, W., Punčochář, P., Bornhöft, D., Bouček, J., Feldmann, H., Guhr, H., Mohaupt, V., Simon, M., Smrtˇák, J., Spoustová, J., Uhlmann, O., (Hrsg.)
    Gewässerschutz im Einzugsgebiet der Elbe. 8. Magdeburger Gewässerschutzseminar, Oktober 1998, Karlsbad (Tschechien)
    B.G. Teubner, Stuttgart, Leipzig, S. 58 - 61
    Volltext (URL)
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1997 (1)

  • Brack, W., Frank, H., (1997):
    A bioassay-directed method for the separation of volatile compounds from landfill leachates
    Chemosphere 34 (4), 849 - 854
    Volltext (URL)
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